Drug Delivery Systems

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Author :
Publisher : World Scientific
ISBN 13 : 9813201061
Total Pages : 391 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis Drug Delivery Systems by : Pieter Stroeve

Download or read book Drug Delivery Systems written by Pieter Stroeve and published by World Scientific. This book was released on 2017-11-27 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the alarming increase in cancer diagnoses and genetic illnesses, traditional drug agents and their delivery media need to be re-evaluated to address a quickly evolving field. With newer smart materials for the controlled release of macromolecules, peptides, genetic material, etc. further complications arise, such as material performance, synthesis, functionalization and targeting, biological identity, and biocompatibility.The book provides a comprehensive overview of the recent developments on 'smart' targeting and drug delivery systems with a variety of carriers like nanoparticles, membranes, and hydrogels. It contains detailed descriptions on the recent trends in this field in the ongoing battle with catastrophic diseases like cancer. This field of research has been in its infancy and continues to face growth, and with it, further challenges and difficulties along the way toward maturity, which are accurately introduced in this book.

Surface Modification of Nanoparticles for Targeted Drug Delivery

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Author :
Publisher : Springer
ISBN 13 : 3030061159
Total Pages : 503 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Surface Modification of Nanoparticles for Targeted Drug Delivery by : Yashwant V Pathak

Download or read book Surface Modification of Nanoparticles for Targeted Drug Delivery written by Yashwant V Pathak and published by Springer. This book was released on 2019-03-11 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

Surfactant Replacement Therapy

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Author :
Publisher : Alan R. Liss
ISBN 13 :
Total Pages : 344 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Surfactant Replacement Therapy by : Donald L. Shapiro

Download or read book Surfactant Replacement Therapy written by Donald L. Shapiro and published by Alan R. Liss. This book was released on 1989 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genotoxic Impurities

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Publisher : John Wiley & Sons
ISBN 13 : 0470934751
Total Pages : 455 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Genotoxic Impurities by : Andrew Teasdale

Download or read book Genotoxic Impurities written by Andrew Teasdale and published by John Wiley & Sons. This book was released on 2011-03-29 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines genotoxic impurities and their impact on the pharmaceutical industry. Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately control genotoxic impurities, thus aiding the reader to develop effective control measures. An opening section covers the development of guidelines and the threshold of toxicological concern (TTC) and is followed by a section on safety aspects, including safety tests in vivo and vitro, and data interpretation. The second section addresses the risk posed by genotoxic impurities from outside sources and from mutagens within DNA. In the final section, the book deals with the quality perspective of genotoxic impurities focused on two critical aspects, the first being the analysis and the second how to practically evaluate the impurities.

Liberation by Oppression

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Publisher : Transaction Publishers
ISBN 13 : 0765805405
Total Pages : 254 pages
Book Rating : 4.7/5 (658 download)

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Book Synopsis Liberation by Oppression by : Thomas Szasz

Download or read book Liberation by Oppression written by Thomas Szasz and published by Transaction Publishers. This book was released on 2003-08-30 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The book is readable and challenging; readers will never see psychiatry in the same way again." -- Choice Reviews Originally called mad-doctoring, psychiatry began in the seventeenth century with the establishing of madhouses and the legal empowering of doctors to incarcerate persons denominated as insane. Until the end of the nineteenth century, every relationship between psychiatrist and patient was based on domination and coercion, as between master and slave. Psychiatry, its emblem the state mental hospital, was a part of the public sphere, the sphere of coercion. The advent of private psychotherapy, at the end of the nineteenth century, split psychiatry in two: some patients continued to be the involuntary inmates of state hospitals; others became the voluntary patients of privately practicing psychotherapists. Psychotherapy was officially defined as a type of medical treatment, but actually was a secular-medical version of the cure of souls. Relationships between therapist and patient, Thomas Szasz argues, was based on cooperation and contract, as is relationships between employer and employee, or, between clergyman and parishioner. Psychotherapy, its emblem the therapist's office, was a part of the private sphere, the contract. Through most of the twentieth century, psychiatry was a house divided-half-slave, and half-free. During the past few decades, psychiatry became united again: all relations between psychiatrists and patients, regardless of the nature of the interaction between them, are now based on actual or potential coercion. This situation is the result of two major "reforms" that deprive therapist and patient alike of the freedom to contract with one another: Therapists now have a double duty: they must protect all mental patients-involuntary and voluntary, hospitalized or outpatient, incompetent or competent-from themselves. They must also protect the public from all patients. Persons designated as mental patients may be exempted from responsibility for the deleterious consequences of their own behavior if it is attributed to mental illness. The radical differences between the coercive character of mental hospital practices in the public sphere, and the consensual character of psychotherapeutic practices in the private sphere, are thus destroyed. At the same time, as the scope of psychiatric coercion expands from the mental hospital to the psychiatrist's office, its reach extends into every part of society, from early childhood to old age. Thomas Szasz is professor of psychiatry emeritus at the State University of New York Health Science Center in Syracuse, New York and Adjunct Scholar at the Cato Institute, Washington, DC. He is the author of over two dozen books in fifteen languages, including The Myth of Mental Illness and most recently, Pharmacracy: Medicine and Politics in America. "The book is readable and challenging; readers will never see psychiatry in the same way again."--Choice "Szasz now appears to have been transformed into an ally rather than an enemy of the National Health Service general adult psychiatrist. Szasz's project has always been to argue passionately for a boundry of demarcation around the responsibility and power of psychiatry....But what saves this book from being just another mugging of psychiatry is that Szasz does raise a fundamental question at the core of our discipline. If we restricted our attention only to those clients who wanted to see a psychiatrist, and disengaged from all those who really didn't, how different might our professional practice and experience be?"--The British Journal of Psychiatry

Colorimetric and Fluorimetric Analysis of Organic Compounds and Drugs

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Publisher :
ISBN 13 :
Total Pages : 706 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Colorimetric and Fluorimetric Analysis of Organic Compounds and Drugs by : Maurice Pesez

Download or read book Colorimetric and Fluorimetric Analysis of Organic Compounds and Drugs written by Maurice Pesez and published by . This book was released on 1974 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Minimal Cell

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Publisher : Springer Science & Business Media
ISBN 13 : 9048199441
Total Pages : 296 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis The Minimal Cell by : Pier Luigi Luisi

Download or read book The Minimal Cell written by Pier Luigi Luisi and published by Springer Science & Business Media. This book was released on 2010-11-01 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last ten years there has been a considerable increase of interest on the notion of the minimal cell. With this term we usually mean a cell-like structure containing the minimal and sufficient number of components to be defined as alive, or at least capable of displaying some of the fundamental functions of a living cell. In fact, when we look at extant living cells we realize that thousands of molecules are organized spatially and functionally in order to realize what we call cellular life. This fact elicits the question whether such huge complexity is a necessary condition for life, or a simpler molecular system can also be defined as alive. Obviously, the concept of minimal cell encompasses entire families of cells, from totally synthetic cells, to semi-synthetic ones, to primitive cell models, to simple biomimetic cellular systems. Typically, in the experimental approach to the construction of minimal the main ingredient is the compartment. Lipid vesicles (liposomes) are used to host simple and complex molecular transformations, from single or multiple enzymic reactions, to polymerase chain reactions, to gene expression. Today this research is seen as part of the broader scenario of synthetic biology but it is rooted in origins of life studies, because the construction of a minimal cell might provide biophysical insights into the origins of primitive cells, and the emergence of life on earth. The volume provides an overview of physical, biochemical and functional studies on minimal cells, with emphasis to experimental approaches. 15 International experts report on their innovative contributions to the construction of minimal cells.

Lung Surfactants

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Publisher : CRC Press
ISBN 13 : 9780824704018
Total Pages : 476 pages
Book Rating : 4.7/5 (4 download)

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Book Synopsis Lung Surfactants by : Robert H. Notter

Download or read book Lung Surfactants written by Robert H. Notter and published by CRC Press. This book was released on 2000-07-18 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrating basic and clinical research on the biophysical and physiological functions of pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on surfactant-related lung disease. Manage neonatal respiratory distress syndrome (RDS), acute respiratory distress syndrome (ARDS), and acute lung injury more effectively!

Controlled Pulmonary Drug Delivery

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Publisher : Springer Science & Business Media
ISBN 13 : 1441997458
Total Pages : 560 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Controlled Pulmonary Drug Delivery by : Hugh D.C. Smyth

Download or read book Controlled Pulmonary Drug Delivery written by Hugh D.C. Smyth and published by Springer Science & Business Media. This book was released on 2011-06-24 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pace of new research and level of innovation repeatedly introduced into the field of drug delivery to the lung is surprising given its state of maturity since the introduction of the pressurized metered dose inhaler over a half a century ago. It is clear that our understanding of pulmonary drug delivery has now evolved to the point that inhalation aerosols can be controlled both spatially and temporally to optimize their biological effects. These abilities include controlling lung deposition, by adopting formulation strategies or device technologies, and controlling drug uptake and release through sophisticated particle technologies. The large number of contributions to the scientific literature and variety of excellent texts published in recent years is evidence for the continued interest in pulmonary drug delivery research. This reference text endeavors to bring together the fundamental theory and practice of controlled drug delivery to the airways that is unavailable elsewhere. Collating and synthesizing the material in this rapidly evolving field presented a challenge and ultimately a sense of achievement that is hopefully reflected in the content of the volume.

Running from the Devil

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Publisher : Blake Publishing
ISBN 13 : 9781844544134
Total Pages : 0 pages
Book Rating : 4.5/5 (441 download)

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Book Synopsis Running from the Devil by : Sara Davies

Download or read book Running from the Devil written by Sara Davies and published by Blake Publishing. This book was released on 2007 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Sara was only five years old, her violent father began to sexually abuse her. She suffered in silence for many years, as her father took advantage of her innocence and her mother turned a blind eye to the horrors that were taking place in her own home. Despite the horrors that Sara has endured, she has survived.

Nanotechnology for Nucleic Acid Delivery

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Publisher : Humana Press
ISBN 13 : 9781627031394
Total Pages : 0 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Nanotechnology for Nucleic Acid Delivery by : Manfred Ogris

Download or read book Nanotechnology for Nucleic Acid Delivery written by Manfred Ogris and published by Humana Press. This book was released on 2012-10-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology and nucleic acid based therapies are two emerging fields in science whose combination has the potential to improve quality of life for patients suffering from various diseases that can so far only be treated in an unsatisfactory way. Nucleic acids offer the potential for highly selective treatment of such diseases or the highly specific modulation of gene expression with RNA interference. A key issue for successful nucleic acid therapies is the availability of a suitable delivery system. Here, the field of nanotechnology offers a multitude of possibilities to develop nanosized delivery vectors tailor-made for various local and systemic approaches. In Nanotechnology for Nucleic Acid Delivery: Methods and Protocols, experts in the field cover the area of nanoparticulate delivery of nucleic acids in terms of biosafety, particle synthesis as well as its application in cell culture. Written in the successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Nanotechnology for Nucleic Acid Delivery: Methods and Protocols seeks to serve both professionals and novices with its well-honed methodologies.

Drug Delivery to the Central Nervous System

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Publisher : Humana Press
ISBN 13 : 9781607615286
Total Pages : 0 pages
Book Rating : 4.6/5 (152 download)

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Book Synopsis Drug Delivery to the Central Nervous System by : Kewal K. Jain

Download or read book Drug Delivery to the Central Nervous System written by Kewal K. Jain and published by Humana Press. This book was released on 2009-12-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Playing an important role in the treatment of neurological disorders, the delivery of drugs to central nervous system (CNS), both administered directly and administered systematically for targeted action, encounters a major challenge in the form of the blood-brain barrier (BBB), which limits the access of drugs to the brain substance. In Drug Delivery to the Central Nervous System, experts in the field present essential methods used to deliver therapeutics across the BBB, both in experimental animals and in humans. In addition to those methods, several overviews of innovative methods and their applications are presented in order to give a glimpse of the future of this research. As a volume in the successful Neuromethods series, this book presents its protocols with the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and cutting-edge, Drug Delivery to the Central Nervous System serves as an ideal guide to scientists continuing to pursue knowledge of the delicate interactions between pharmaceuticals and the brain.