Commercializing The Stem Cell Sciences

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Commercializing the Stem Cell Sciences

Author : Olivia Harvey
Publisher : Elsevier
ISBN 13 : 190881814X
Total Pages : 213 pages
Book Rating : 4.9/5 (88 download)

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Book Synopsis Commercializing the Stem Cell Sciences by : Olivia Harvey

Download or read book Commercializing the Stem Cell Sciences written by Olivia Harvey and published by Elsevier. This book was released on 2012-10-16 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Promising new developments in biomedical technology such as stem cell science are widely endorsed by governments keen to reduce spiralling healthcare costs, clinicians focused on patient care, and patients demanding revolutionary new treatments. Commercializing the stem cell sciences offers a comparative analysis of the commercial methods adopted in the global stem cell industries. It seeks to establish whether there is an optimum commercial model and to examine what emerging companies can learn from their predecessors. Following an introduction to stem cell sciences and the problems involved in their commercialization, the book begins with a discussion of stem cell treatments from a global perspective, and the role of innovation in the commercialization of biotechnology in general. In the second half of the book, chapters focus on the different strategies that can be employed and their relative risks and values, before a conclusion that looks at potential new developments in the field. - In-depth discussion of case studies of products undergoing development - Focus on commercial optimization of stem cell treatments - Analysis in a global context and covering a diverse range of countries

Stem Cell Manufacturing

Author : Joaquim M.S. Cabral
Publisher : Elsevier
ISBN 13 : 0444632662
Total Pages : 342 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Stem Cell Manufacturing by : Joaquim M.S. Cabral

Download or read book Stem Cell Manufacturing written by Joaquim M.S. Cabral and published by Elsevier. This book was released on 2016-07-24 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product. The advent of stem cell research unveiled the therapeutic potential of stem cells and their derivatives and increased the awareness of the public and scientific community for the topic. The successful manufacturing of stem cells and their derivatives is expected to have a positive impact in the society since it will contribute to widen the offer of therapeutic solutions to the patients. Fully defined cellular products can be used to restore the structure and function of damaged tissues and organs and to develop stem cell-based cellular therapies for the treatment of cancer and hematological disorders, autoimmune and other inflammatory diseases and genetic disorders. - Presents the first 'Flowchart' of stem cell manufacturing enabling easy understanding of the various processes in a sequential and coherent manner - Covers all bioprocess technologies required for the transfer of the bench findings to the clinic including the process components: cell signals, bioreactors, modeling, automation, safety, etc. - Presents comprehensive coverage of a true multidisciplinary topic by bringing together specialists in their particular area - Provides the basics of the processes and identifies the issues to be resolved for large scale cell culture by the bioengineer - Addresses the critical need in bioprocessing for the successful delivery of stem cell technology to the market place by involving professional engineers in sections of the book

Stem Cells

Author : Christine L. Mummery
Publisher : Academic Press
ISBN 13 : 0124115675
Total Pages : 446 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Stem Cells by : Christine L. Mummery

Download or read book Stem Cells written by Christine L. Mummery and published by Academic Press. This book was released on 2014-05-23 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies. - Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy - Includes extensive coverage of adult and embryonic stem cells both historically and in contemporary practice - Richly illustrated to assist in understanding how research is done and the current hurdles to clinical practice

Stem Cell Biology and Tissue Engineering in Dental Sciences

Author : Ajaykumar Vishwakarma
Publisher : Academic Press
ISBN 13 : 0123977789
Total Pages : 933 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Stem Cell Biology and Tissue Engineering in Dental Sciences by : Ajaykumar Vishwakarma

Download or read book Stem Cell Biology and Tissue Engineering in Dental Sciences written by Ajaykumar Vishwakarma and published by Academic Press. This book was released on 2014-11-05 with total page 933 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences. It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs. Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues. This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration. - Diligently covers all the aspects related to stem cell biology and tissue engineering in dental sciences: basic science, research, clinical application and commercialization - Provides detailed descriptions of new, modern technologies, fabrication techniques employed in the fields of stem cells, biomaterials and tissue engineering research including details of latest advances in nanotechnology - Includes a description of stem cell biology with details focused on oral and craniofacial stem cells and their potential research application throughout medicine - Print book is available and black and white, and the ebook is in full color

Stem Cell Research

Author : Joseph Panno
Publisher : Infobase Publishing
ISBN 13 : 0816067333
Total Pages : 193 pages
Book Rating : 4.8/5 (16 download)

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Book Synopsis Stem Cell Research by : Joseph Panno

Download or read book Stem Cell Research written by Joseph Panno and published by Infobase Publishing. This book was released on 2014-05-14 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout its development in the past few years, controversy and debate have surrounded stem cell research.

Stem Cell Therapies

Author : Adam C. Berger
Publisher : National Academy Press
ISBN 13 : 9780309303002
Total Pages : 108 pages
Book Rating : 4.3/5 (3 download)

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Book Synopsis Stem Cell Therapies by : Adam C. Berger

Download or read book Stem Cell Therapies written by Adam C. Berger and published by National Academy Press. This book was released on 2014-06-18 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells offer tremendous promise for advancing health and medicine. Whether being used to replace damaged cells and organs or else by supporting the body's intrinsic repair mechanisms, stem cells hold the potential to treat such debilitating conditions as Parkinson's disease, diabetes, and spinal cord injury. Clinical trials of stem cell treatments are under way in countries around the world, but the evidence base to support the medical use of stem cells remains limited. Despite this paucity of clinical evidence, consumer demand for treatments using stem cells has risen, driven in part by a lack of available treatment options for debilitating diseases as well as direct-to-consumer advertising and public portrayals of stem cell-based treatments. Clinics that offer stem cell therapies for a wide range of diseases and conditions have been established throughout the world, both in newly industrialized countries such as China, India, and Mexico and in developed countries such as the United States and various European nations. Though these therapies are often promoted as being established and effective, they generally have not received stringent regulatory oversight and have not been tested with rigorous trials designed to determine their safety and likely benefits. In the absence of substantiated claims, the potential for harm to patients - as well as to the field of stem cell research in general - may outweigh the potential benefits. To explore these issues, the Institute of Medicine, the National Academy of Sciences, and the International Society for Stem Cell Research held a workshop in November 2013. "Stem Cell Therapies" summarizes the workshop. Researchers, clinicians, patients, policy makers, and others from North America, Europe, and Asia met to examine the global pattern of treatments and products being offered, the range of patient experiences, and options to maximize the well-being of patients, either by protecting them from treatments that are dangerous or ineffective or by steering them toward treatments that are effective. This report discusses the current environment in which patients are receiving unregulated stem cell offerings, focusing on the treatments being offered and their risks and benefits. The report considers the evidence base for clinical application of stem cell technologies and ways to assure the quality of stem cell offerings.

Stem Cell Drugs - A New Generation of Biopharmaceuticals

Author : Phuc Van Pham
Publisher : Springer
ISBN 13 : 3319993283
Total Pages : 162 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Stem Cell Drugs - A New Generation of Biopharmaceuticals by : Phuc Van Pham

Download or read book Stem Cell Drugs - A New Generation of Biopharmaceuticals written by Phuc Van Pham and published by Springer. This book was released on 2018-10-25 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable resource discusses the current revolution in stem cell-based drugs and their potential use in clinical applications. Each chapter is contributed by a pre-eminent scientist in the field. An introductory section presents current stem cell drugs and stem cell-based products and a discussion of production, quality control, mechanisms, and efficacy. Following sections include discussions on stem cell-derived microvesicles based products, and derived exosomes based products. Stem Cell Drugs - A New Generation of Biopharmaceuticals and the other books in the Stem Cells in Clinical Applications series are invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering. This groundbreaking volume is also essential reading for those researching or studying drug development or pharmaceutical science.

Advances in Application of Stem Cells: From Bench to Clinics

Author : Firdos Alam Khan
Publisher : Springer Nature
ISBN 13 : 3030781011
Total Pages : 320 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Advances in Application of Stem Cells: From Bench to Clinics by : Firdos Alam Khan

Download or read book Advances in Application of Stem Cells: From Bench to Clinics written by Firdos Alam Khan and published by Springer Nature. This book was released on 2021-09-14 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of stem cell biology is expanding with a continued surge of new information related to its applications. Over past few years, stem cells have been extensively used in cell therapy, tissue engineering, in vitro drug testing among others. At the moment there is no single book available which comprehensively describes the significance of various application of stem cells derived from embryonic and adult sources from lab to clinics. In this edited volume, we discuss basics and advanced topics of stem cells to help researchers, students and professional find the most important information in a single source of updated information about stem cells and relevant applications. This book is divided in 12 chapters and covers topics such as in vitro cell culture, 3D cell culture, cell therapy, tissue engineering, cell factory, cell functionality, in vitro drug testing, organ development, autologous transplantation, allogeneic transplantation, adult stem cells, multipotent stem cells, induced pluripotent stem cells, a pluripotent and embryonic stem cells.

Perinatal Stem Cells

Author : Anthony Atala
Publisher : Academic Press
ISBN 13 : 0128120630
Total Pages : 438 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Perinatal Stem Cells by : Anthony Atala

Download or read book Perinatal Stem Cells written by Anthony Atala and published by Academic Press. This book was released on 2018-06-14 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton's jelly. It's compiled by leading experts in the field, offering readers detailed insights into sources of perinatal stem cells and their potential for disease treatment. Therapeutic applications of perinatal stem cells include the treatment of in utero and pregnancy related diseases, cardiac disease, liver disease, pulmonary disease, inflammatory diseases, for hematopoietic regeneration, and for neural protection after stroke or traumatic brain injury. In addition, the rapid advance in clinical translation and commercialization of perinatal stem cell therapies is highlighted in a section on Clinical and Industry Perspective which provides insight into the new opportunities and challenges involved in this novel and exciting industry. - Explores current clinical and pre-clinical application of stem cells derived from perinatal sources - Offers detailed insight into sources of perinatal stem cells and their potential for disease treatment - Discusses progress in the manufacturing, banking and clinical translation of perinatal stem cells - Edited by a world-renowned team to present a complete story of the development and promise of perinatal stem cells

Science and the University

Author : Paula E. Stephan
Publisher : Univ of Wisconsin Press
ISBN 13 : 0299224805
Total Pages : 318 pages
Book Rating : 4.2/5 (992 download)

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Book Synopsis Science and the University by : Paula E. Stephan

Download or read book Science and the University written by Paula E. Stephan and published by Univ of Wisconsin Press. This book was released on 2007-09-13 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Science and the University investigates the tremendous changes that have taken place in university research over the past several decades, gauging the current state of research in higher education and examining issues and challenges crucial to its future. Scientific research increasingly dominates the aims and agendas of many American universities, and this proliferation—and changes in the way research is conducted—has given rise to important questions about the interrelations of higher education, funding for scientific research, and government policy. The cost of doing science, the commercialization of university research, the changing composition and number of Ph.D. students, the effect of scientific research on other university programs—these are just a few of the many issues explored in this volume from the vantage points of scholars in such diverse fields as economics, biochemistry, genetics, and labor studies.

Life as Surplus

Author : Melinda E. Cooper
Publisher : University of Washington Press
ISBN 13 : 0295990317
Total Pages : 233 pages
Book Rating : 4.2/5 (959 download)

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Book Synopsis Life as Surplus by : Melinda E. Cooper

Download or read book Life as Surplus written by Melinda E. Cooper and published by University of Washington Press. This book was released on 2011-02-01 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on the period between the 1970s and the present, Life as Surplus is a pointed and important study of the relationship between politics, economics, science, and cultural values in the United States today. Melinda Cooper demonstrates that the history of biotechnology cannot be understood without taking into account the simultaneous rise of neoliberalism as a political force and an economic policy. From the development of recombinant DNA technology in the 1970s to the second Bush administration's policies on stem cell research, Cooper connects the utopian polemic of free-market capitalism with growing internal contradictions of the commercialized life sciences. The biotech revolution relocated economic production at the genetic, microbial, and cellular level. Taking as her point of departure the assumption that life has been drawn into the circuits of value creation, Cooper underscores the relations between scientific, economic, political, and social practices. In penetrating analyses of Reagan-era science policy, the militarization of the life sciences, HIV politics, pharmaceutical imperialism, tissue engineering, stem cell science, and the pro-life movement, the author examines the speculative impulses that have animated the growth of the bioeconomy. At the very core of the new post-industrial economy is the transformation of biological life into surplus value. Life as Surplus offers a clear assessment of both the transformative, therapeutic dimensions of the contemporary life sciences and the violence, obligation, and debt servitude crystallizing around the emerging bioeconomy.

The Global Politics of Human Embryonic Stem Cell Science

Author : H. Gottweis
Publisher : Springer
ISBN 13 : 0230594360
Total Pages : 235 pages
Book Rating : 4.2/5 (35 download)

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Book Synopsis The Global Politics of Human Embryonic Stem Cell Science by : H. Gottweis

Download or read book The Global Politics of Human Embryonic Stem Cell Science written by H. Gottweis and published by Springer. This book was released on 2009-01-15 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on a wide range of interviews and primary and secondary sources, this book investigates the dynamic interactions between national regulatory formation and the global biopolitics of regenerative medicine and human embryonic stem cell science.

Building on Canada's Strengths in Regenerative Medicine

Author : Workshop Steering Committee
Publisher : Council of Canadian Academies
ISBN 13 : 1926522230
Total Pages : 60 pages
Book Rating : 4.9/5 (265 download)

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Book Synopsis Building on Canada's Strengths in Regenerative Medicine by : Workshop Steering Committee

Download or read book Building on Canada's Strengths in Regenerative Medicine written by Workshop Steering Committee and published by Council of Canadian Academies. This book was released on 2017 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: K2P 2K3 Notice: The project that is the subject of this report was undertaken with the approval of the Board of Governors of the Council of Canadian Academies (CCA). [...] Any opinions, findings, or conclusions expressed in this publication are those of the authors, the Steering Committee of the Workshop on the Opportunities and Challenges for Regenerative Medicine in Canada and do not necessarily represent the views of their organizations of affiliation or employment, or the sponsoring organization, Innovation, Science and Economic Development Canada. [...] The Council of Canadian Academies iii the Council of Canadian academies Science Advice in the Public Interest The Council of Canadian Academies (CCA) is an The Canadian Academy of Engineering (CAE) independent, not-for-profit organization that supports The CAE is the national institution through which Canada's independent, science-based, authoritative expert assessments most distinguished and expe [...] My personal thanks also to the other members of the Steering Committee who donated their time and Recognition of the importance and potential of regenerative expertise to plan the workshop and ensure this summary medicine led to the workshop summarized in this report. [...] The role of the report review monitor is to ensure that the Steering Committee give full and fair consideration to the submissions of the report reviewers.

The Delivery of Regenerative Medicines and Their Impact on Healthcare

Author : Catherine Prescott
Publisher : CRC Press
ISBN 13 : 1040197760
Total Pages : 355 pages
Book Rating : 4.0/5 (41 download)

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Book Synopsis The Delivery of Regenerative Medicines and Their Impact on Healthcare by : Catherine Prescott

Download or read book The Delivery of Regenerative Medicines and Their Impact on Healthcare written by Catherine Prescott and published by CRC Press. This book was released on 2016-04-19 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now that prohibitions against stem cell research are relaxing, it is time for the field to move forward with the advances that promise to eliminate so much human suffering. However, it would be naive to ignore the fact that regenerative medicines pose a whole new set of challenges to an industry sector that for decades has geared itself to the deve

The SAGE Encyclopedia of Stem Cell Research

Author : Eric E. Bouhassira
Publisher : SAGE Publications
ISBN 13 : 1483347672
Total Pages : 1517 pages
Book Rating : 4.4/5 (833 download)

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Book Synopsis The SAGE Encyclopedia of Stem Cell Research by : Eric E. Bouhassira

Download or read book The SAGE Encyclopedia of Stem Cell Research written by Eric E. Bouhassira and published by SAGE Publications. This book was released on 2015-06-15 with total page 1517 pages. Available in PDF, EPUB and Kindle. Book excerpt: The SAGE Encyclopedia of Stem Cell Research, Second Edition is filled with new procedures and exciting medical breakthroughs, including executive orders from the Obama administration reversing barriers to research imposed under the Bush administration, court rulings impacting NIH funding of research based on human embryonic stem cells, edicts by the Papacy and other religious leaders, and the first success in cloning human stem cells. Stem cell biology is clearly fueling excitement and potential in traditional areas of developmental biology and in the field of regenerative medicine, where they are believed to hold much promise in addressing any number of intractable medical conditions. This updated second edition encyclopedia will expand on information that was given in the first edition and present more than 270 new and updated articles that explore major topics in ways accessible to nonscientists, thus bringing readers up-to-date with where stem cell biology stands today, including new and evolving ethical, religious, legal, social, and political perspectives. This second edition reference work will serve as a universal resource for all public and academic libraries. It is an excellent foundation for anyone who is interested in the subject area of stem cell biology. Key Features: Reader’s Guide, Further Readings, Cross References, Chronology, Resource Guide, Index A Glossary will elucidate stem cell terminology for the nonscientist Statistics and selected reprints of major journal articles that pertain to milestones achieved in stem cell research Documents from Congressional Hearings on stem cells and cloning Reports to the President’s Council on Bioethics, and more

Stem Cells: New Frontiers In Science And Ethics

Author : John Harris
Publisher : World Scientific
ISBN 13 : 9814458082
Total Pages : 297 pages
Book Rating : 4.8/5 (144 download)

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Book Synopsis Stem Cells: New Frontiers In Science And Ethics by : John Harris

Download or read book Stem Cells: New Frontiers In Science And Ethics written by John Harris and published by World Scientific. This book was released on 2012-03-27 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fast-moving and ever-changing, stem cell science and research presents ongoing ethical and legal challenges in many countries. Each development and innovation throws up new challenges. This is the case even where new developments initially seem to solve old dilemmas. Sometimes it becomes evident that new science does not in fact solve old problems and, for that reason, the ethical issues remain. In recognition of this, this book presents innovative and creative analyses of a range of ethical and legal challenges raised by stem cell research and its potential and actual application.The editors of this collection have brought together experts from ethics and law to bring fresh perspectives on the use of and research on stem cells. The chapters in this collection range across a number of different issues in the debate on stem cells, from the ethical dilemmas of conducting stem cell research to those of the clinical application of stem cell technology. Each chapter gives an in-depth and comprehensive analysis of the ethical or legal issues at stake. The early chapters give engaging new expositions on the permissibility of using embryos in stem cell research, in particular challenging our views about how we view and ‘construct’ the embryo in debates regarding stem cells. Later chapters move on to actual and potential clinical uses of stem cells and present novel arguments about these.

Human Stem Cell Manual

Author : Suzanne Peterson
Publisher : Academic Press
ISBN 13 : 0123854741
Total Pages : 652 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Human Stem Cell Manual by : Suzanne Peterson

Download or read book Human Stem Cell Manual written by Suzanne Peterson and published by Academic Press. This book was released on 2012-10-22 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual is a comprehensive compilation of "methods that work" for deriving, characterizing, and differentiating hPSCs, written by the researchers who developed and tested the methods and use them every day in their laboratories. The manual is much more than a collection of recipes; it is intended to spark the interest of scientists in areas of stem cell biology that they may not have considered to be important to their work. The second edition of the Human Stem Cell Manual is an extraordinary laboratory guide for both experienced stem cell researchers and those just beginning to use stem cells in their work. - Offers a comprehensive guide for medical and biology researchers who want to use stem cells for basic research, disease modeling, drug development, and cell therapy applications - Provides a cohesive global view of the current state of stem cell research, with chapters written by pioneering stem cell researchers in Asia, Europe, and North America - Includes new chapters devoted to recently developed methods, such as iPSC technology, written by the scientists who made these breakthroughs