Advances In Application Of Stem Cells From Bench To Clinics

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Advances in Application of Stem Cells: From Bench to Clinics

Author : Firdos Alam Khan
Publisher :
ISBN 13 : 9783030781026
Total Pages : 0 pages
Book Rating : 4.7/5 (81 download)

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Book Synopsis Advances in Application of Stem Cells: From Bench to Clinics by : Firdos Alam Khan

Download or read book Advances in Application of Stem Cells: From Bench to Clinics written by Firdos Alam Khan and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of stem cell biology is expanding with a continued surge of new information related to its applications. Over past few years, stem cells have been extensively used in cell therapy, tissue engineering, in vitro drug testing among others. At the moment there is no single book available which comprehensively describes the significance of various application of stem cells derived from embryonic and adult sources from lab to clinics. In this edited volume, we discuss basics and advanced topics of stem cells to help researchers, students and professional find the most important information in a single source of updated information about stem cells and relevant applications. This book is divided in 12 chapters and covers topics such as in vitro cell culture, 3D cell culture, cell therapy, tissue engineering, cell factory, cell functionality, in vitro drug testing, organ development, autologous transplantation, allogeneic transplantation, adult stem cells, multipotent stem cells, induced pluripotent stem cells, a pluripotent and embryonic stem cells.

Advances in Application of Stem Cells: From Bench to Clinics

Author : Firdos Alam Khan
Publisher : Springer Nature
ISBN 13 : 3030781011
Total Pages : 320 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Advances in Application of Stem Cells: From Bench to Clinics by : Firdos Alam Khan

Download or read book Advances in Application of Stem Cells: From Bench to Clinics written by Firdos Alam Khan and published by Springer Nature. This book was released on 2021-09-14 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of stem cell biology is expanding with a continued surge of new information related to its applications. Over past few years, stem cells have been extensively used in cell therapy, tissue engineering, in vitro drug testing among others. At the moment there is no single book available which comprehensively describes the significance of various application of stem cells derived from embryonic and adult sources from lab to clinics. In this edited volume, we discuss basics and advanced topics of stem cells to help researchers, students and professional find the most important information in a single source of updated information about stem cells and relevant applications. This book is divided in 12 chapters and covers topics such as in vitro cell culture, 3D cell culture, cell therapy, tissue engineering, cell factory, cell functionality, in vitro drug testing, organ development, autologous transplantation, allogeneic transplantation, adult stem cells, multipotent stem cells, induced pluripotent stem cells, a pluripotent and embryonic stem cells.

Stem Cells

Author : Ariff Bongso
Publisher : World Scientific
ISBN 13 : 9814289388
Total Pages : 721 pages
Book Rating : 4.8/5 (142 download)

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Book Synopsis Stem Cells by : Ariff Bongso

Download or read book Stem Cells written by Ariff Bongso and published by World Scientific. This book was released on 2011 with total page 721 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cell biology has drawn tremendous interest in recent years as it promises cures for a variety of incurable diseases. This book deals with the basic and clinical aspects of stem cell research and involves work on the full spectrum of stem cells isolated today. It also covers the conversion of stem cell types into a variety of useful tissues which may be used in the future for transplantation therapy. It is thus aimed at undergraduates, postgraduates, scientists, embryologists, doctors, tissue engineers and anyone who wishes to gain some insight into stem cell biology. This book is important as it is comprehensive and covers all aspects of stem cell biology, from basic research to clinical applications. It will have 33 chapters written by renowned stem cell scientists worldwide. It will be up-to-date and all the chapters include self-explanatory figures, color photographs, graphics and tables. It will be easy to read and give the reader a complete understanding and state of the art of the exciting science and its applications.

Stem Cell Manufacturing

Author : Joaquim M. S. Cabral
Publisher : Elsevier
ISBN 13 : 0444632662
Total Pages : 340 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Stem Cell Manufacturing by : Joaquim M. S. Cabral

Download or read book Stem Cell Manufacturing written by Joaquim M. S. Cabral and published by Elsevier. This book was released on 2016-07-24 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product. The advent of stem cell research unveiled the therapeutic potential of stem cells and their derivatives and increased the awareness of the public and scientific community for the topic. The successful manufacturing of stem cells and their derivatives is expected to have a positive impact in the society since it will contribute to widen the offer of therapeutic solutions to the patients. Fully defined cellular products can be used to restore the structure and function of damaged tissues and organs and to develop stem cell-based cellular therapies for the treatment of cancer and hematological disorders, autoimmune and other inflammatory diseases and genetic disorders. Presents the first ‘Flowchart‘ of stem cell manufacturing enabling easy understanding of the various processes in a sequential and coherent manner Covers all bioprocess technologies required for the transfer of the bench findings to the clinic including the process components: cell signals, bioreactors, modeling, automation, safety, etc. Presents comprehensive coverage of a true multidisciplinary topic by bringing together specialists in their particular area Provides the basics of the processes and identifies the issues to be resolved for large scale cell culture by the bioengineer Addresses the critical need in bioprocessing for the successful delivery of stem cell technology to the market place by involving professional engineers in sections of the book

Advances in Stem Cell Therapy

Author : Nagwa El-Badri
Publisher : Humana Press
ISBN 13 : 3319291491
Total Pages : 310 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Advances in Stem Cell Therapy by : Nagwa El-Badri

Download or read book Advances in Stem Cell Therapy written by Nagwa El-Badri and published by Humana Press. This book was released on 2016-11-18 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book reviews the main approaches for generation of differentiated cells from various types of stem cells, including embryonic, placental and cord blood stem cells through marrow, adipose tissue and dental pulp. The book starts with an overview of experimental protocols applied to generate insulin secreting cells, neural cells, heart cells, and other tissue specific cells ex vivo and in experimental animals. This is followed by exhaustive review of clinical trials in these pathologies. It continues with a comparison of the merits of successful transplantation in humans versus animal experimentation, and highlights the most promising clinical applications in the field. Special chapters are devoted to the topic of tissue engineering and modern synthetic and biological scaffolds. It is essential reading for scientists and researchers in tissue engineering and stem cell research as well as clinicians who are involved in developing or testing stem cell therapies.

A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics

Author : Xiao-Dong Chen
Publisher : Academic Press
ISBN 13 : 0128119217
Total Pages : 544 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics by : Xiao-Dong Chen

Download or read book A Roadmap to Nonhematopoietic Stem Cell-Based Therapeutics written by Xiao-Dong Chen and published by Academic Press. This book was released on 2018-08-31 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Roadmap to Non-hematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic is a resource that provides an overview of the principles of stem cell therapy, the promises and challenges of using stem cells for treating various clinical conditions, and future perspectives. The overall goal is to facilitate the translation of basic research on stem cells to clinical applications. The properties of stem cells from various sources are reviewed and the advantages and disadvantages of each for clinical use are discussed. Modifying stem cell properties through preconditioning strategies using physical, chemical, genetic, and molecular manipulation to improve cell survival, increase cell differentiation potential, enhance production of paracrine factors, and facilitate homing to the site of injury or disease upon transplantation are reviewed. Various routes of stem cell administration and dosing, and the duration of effects, are explored. Individual chapters are written by experts in the field and focus on the use of stem cells in treating various degenerative diseases, autoimmune diseases, wound healing, cardiovascular disease, spinal cord injury, oral and dental diseases, and skeletal disorders. Finally, experts in the regulatory arena discuss mechanisms used in different countries for approving the use of stem cells to treat diseases and many common issues that are typically encountered while seeking approval for this class of therapeutic agent. Offers advanced students, as well as new researchers, an overview of the principles of stem cell therapy Discusses a wide array of pressing clinical issues with stem cell-based therapies so that new ideas in the laboratory can be efficiently translated to the clinic through better designed clinical trials Helps clarify current regulatory mechanisms so that the safe use of stem cells for treating a variety of diseases can move forward Fosters cross-disciplinary dialogue between research scientists and physicians to accelerate the safe implementation of efficacious cell therapies

Advances in Tissue Engineering

Author : Julia M. Polak
Publisher : World Scientific
ISBN 13 : 1848161824
Total Pages : 947 pages
Book Rating : 4.8/5 (481 download)

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Book Synopsis Advances in Tissue Engineering by : Julia M. Polak

Download or read book Advances in Tissue Engineering written by Julia M. Polak and published by World Scientific. This book was released on 2008 with total page 947 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Tissue Engineering is a unique volume and the first of its kind to bring together leading names in the field of tissue engineering and stem cell research. A relatively young science, tissue engineering can be seen in both scientific and sociological contexts and successes in the field are now leading to clinical reality. This book attempts to define the path from basic science to practical application. A contribution from the UK Stem Cell Bank and opinions of venture capitalists offer a variety of viewpoints, and exciting new areas of stem cell biology are highlighted. With over fifty stellar contributors, this book presents the most up-to-date information in this very topical and exciting field.

Pluripotent Stem Cells

Author : Minoru Tomizawa
Publisher : BoD – Books on Demand
ISBN 13 : 9535124714
Total Pages : 534 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Pluripotent Stem Cells by : Minoru Tomizawa

Download or read book Pluripotent Stem Cells written by Minoru Tomizawa and published by BoD – Books on Demand. This book was released on 2016-07-20 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pluripotent stem cells have distinct characteristics: self-renewal and the potential to differentiate into various somatic cells. In recent years, substantial advances have been made from basic science to clinical applications. The vast amount knowledge available makes obtaining concise yet sufficient information difficult, hence the purpose of this book. In this book, embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells are discussed. The book is divided into five sections: pluripotency, culture methods, toxicology, disease models, and regenerative medicine. The topics covered range from new concepts to current technologies. Readers are expected to gain useful information from expert contributors.

Stem Cells—Advances in Research and Application: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481692534
Total Pages : 896 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Stem Cells—Advances in Research and Application: 2013 Edition by :

Download or read book Stem Cells—Advances in Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem Cells—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Adult Stem Cells. The editors have built Stem Cells—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Adult Stem Cells in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Stem Cells—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Human Embryonic Stem Cells

Author : Arlene Chiu
Publisher : Springer Science & Business Media
ISBN 13 : 1592594239
Total Pages : 455 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Human Embryonic Stem Cells by : Arlene Chiu

Download or read book Human Embryonic Stem Cells written by Arlene Chiu and published by Springer Science & Business Media. This book was released on 2003-08-01 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.

Mesenchymal Stem Cell Therapy

Author : Lucas G. Chase
Publisher : Springer Science & Business Media
ISBN 13 : 1627032002
Total Pages : 458 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Mesenchymal Stem Cell Therapy by : Lucas G. Chase

Download or read book Mesenchymal Stem Cell Therapy written by Lucas G. Chase and published by Springer Science & Business Media. This book was released on 2012-12-12 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, significant efforts have been made to develop stem cell-based therapies for difficult to treat diseases. Multipotent mesenchymal stromal cells, also referred to as mesenchymal stem cells (MSCs), appear to hold great promise in regards to a regenerative cell-based therapy for the treatment of these diseases. Currently, more than 200 clinical trials are underway worldwide exploring the use of MSCs for the treatment of a wide range of disorders including bone, cartilage and tendon damage, myocardial infarction, graft-versus-host disease, Crohn’s disease, diabetes, multiple sclerosis, critical limb ischemia and many others. MSCs were first identified by Friendenstein and colleagues as an adherent stromal cell population within the bone marrow with the ability to form clonogenic colonies in vitro. In regards to the basic biology associated with MSCs, there has been tremendous progress towards understanding this cell population’s phenotype and function from a range of tissue sources. Despite enormous progress and an overall increased understanding of MSCs at the molecular and cellular level, several critical questions remain to be answered in regards to the use of these cells in therapeutic applications. Clinically, both autologous and allogenic approaches for the transplantation of MSCs are being explored. Several of the processing steps needed for the clinical application of MSCs, including isolation from various tissues, scalable in vitro expansion, cell banking, dose preparation, quality control parameters, delivery methods and numerous others are being extensively studied. Despite a significant number of ongoing clinical trials, none of the current therapeutic approaches have, at this point, become a standard of care treatment. Although exceptionally promising, the clinical translation of MSC-based therapies is still a work in progress. The extensive number of ongoing clinical trials is expected to provide a clearer path forward for the realization and implementation of MSCs in regenerative medicine. Towards this end, reviews of current clinical trial results and discussions of relevant topics association with the clinical application of MSCs are compiled in this book from some of the leading researchers in this exciting and rapidly advancing field. Although not absolutely all-inclusive, we hope the chapters within this book can promote and enable a better understanding of the translation of MSCs from bench-to-bedside and inspire researchers to further explore this promising and quickly evolving field.

Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench-to-Bedside

Author : Kuldip S. Sidhu
Publisher : Bentham Science Publishers
ISBN 13 : 1608052893
Total Pages : 250 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench-to-Bedside by : Kuldip S. Sidhu

Download or read book Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench-to-Bedside written by Kuldip S. Sidhu and published by Bentham Science Publishers. This book was released on 2012 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Pluripotent stem cells have garnered tremendous interest in recent years, which is primarily driven by the hope of finding a cure for several debilitating human diseases. Cell transplantation (regeneratve medicine) offers considerable therapeutic potentia"

Stem Cells

Author : Mariusz Z. Ratajczak
Publisher : Springer Nature
ISBN 13 : 3030312062
Total Pages : 410 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Stem Cells by : Mariusz Z. Ratajczak

Download or read book Stem Cells written by Mariusz Z. Ratajczak and published by Springer Nature. This book was released on 2020-01-02 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since different types of stem cells for therapeutic applications have recently been proposed, this timely volume explores various sources of stem cells for tissue and organ regeneration and discusses their advantages and limitations. Also discussed are pros and cons for using embryonic stem cells, induced pluripotent stem cells, and adult stem cells isolated from postnatal tissues. Different types of adult stem cells for therapeutic applications are also reviewed, including hematopoietic stem cells, epidermal stem cells, endothelial progenitors, neural stem cells, mesenchymal stem cells, and very small embryonic-like stem cells. This book also addresses paracrine effects of stem cells in regenerative medicine that are mediated by extracellular microvesicles and soluble secretome. Finally, potential applications of stem cells in cardiology, gastroenterology, neurology, immunotherapy, and aging are presented. This is an ideal book for students and researchers working in the stem cell research field.

Engineering and Application of Pluripotent Stem Cells

Author : Ulrich Martin
Publisher : Springer
ISBN 13 : 9783030088170
Total Pages : 228 pages
Book Rating : 4.0/5 (881 download)

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Book Synopsis Engineering and Application of Pluripotent Stem Cells by : Ulrich Martin

Download or read book Engineering and Application of Pluripotent Stem Cells written by Ulrich Martin and published by Springer. This book was released on 2019-01-03 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the latest biotechnological advances with pluripotent stem cells, exploring their application in tissue engineering and medicinal chemistry. Chapters from expert contributors cover topics such as the production of transgene-free induced pluripotent stem cells (iPSCs), expansion, controlled differentiation and programming of pluripotent stem cells, and their genetic instability. Particular attention is given to the application of the pluripotent stem cells for vascularision of engineered tissue and for drug screening. This book will appeal to researchers working in regenerative medicine and drug discovery, and to bioengineers and professionals interested in stem cell research.

Stem Cell And Tissue Engineering

Author : Dr.Sumira Malik
Publisher : Sankalp Publication
ISBN 13 : 9390468760
Total Pages : 74 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Stem Cell And Tissue Engineering by : Dr.Sumira Malik

Download or read book Stem Cell And Tissue Engineering written by Dr.Sumira Malik and published by Sankalp Publication. This book was released on with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book requires the basic knowledge of human physiology, cell biology, Molecular Biology, Animal biotechnology and Biochemistry. The goal of this book is to provide students, teachers and researchers the essence of the key concepts and deep knowledge of stem cells basics, stem cell technology and their application in field of regenerative medicine applying these thematic studies of stem cell technology and tissue engineering. Stem cell technology and it’s application in Tissue engineering is an interdisciplinary field of biomedical research compiling Biosciences, material sciences and Bioengineering to progress the treatment of damaged, degenerated and diseased tissue through maintenance, repair, and replacement methodology. This ever-emerging area of research applies in numerous medical and interdisciplinary streams of stem cell biology, tissue regeneration, regenerative medicine and Bioengineering. These stem cell biology techniques and tissue engineering strategies are now being progressively more evaluated and progressed as potential treatments of neuro degeneration disorders, regenerative medicine, artificial organ development, organ bioengineering, and transplant medicine. The book seeks to put an end to many queries and doubts about an understanding of the clinical need for stem cell therapy and tissue engineering in regenerative medicine, knowledge of stem cell sources and their isolation, characterization, principle of tissue engineering using basic elements and concept of tissue engineering. Further, the need for biomaterials, their design, fabrication and used of the biomaterials for in vitro, in vivo and clinical application are also covered. This book discusses the emergence of stem cell technology, tissue engineering and our current understanding of the Biotechnology and Biological sciences discipline

Guidelines for Human Embryonic Stem Cell Research

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309096537
Total Pages : 224 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Guidelines for Human Embryonic Stem Cell Research by : National Research Council

Download or read book Guidelines for Human Embryonic Stem Cell Research written by National Research Council and published by National Academies Press. This book was released on 2005-09-15 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1998, the volume of research being conducted using human embryonic stem (hES) cells has expanded primarily using private funds because of restrictions on the use of federal funds for such research. Given limited federal involvement, privately funded hES cell research has thus far been carried out under a patchwork of existing regulations, many of which were not designed with this research specifically in mind. In addition, hES cell research touches on many ethical, legal, scientific, and policy issues that are of concern to the public. This report provides guidelines for the conduct of hES cell research to address both ethical and scientific concerns. The guidelines are intended to enhance the integrity of privately funded hES cell research by encouraging responsible practices in the conduct of that research.

Tissue Engineering

Author : Clemens Van Blitterswijk
Publisher : Academic Press
ISBN 13 : 0124202101
Total Pages : 896 pages
Book Rating : 4.1/5 (242 download)

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Book Synopsis Tissue Engineering by : Clemens Van Blitterswijk

Download or read book Tissue Engineering written by Clemens Van Blitterswijk and published by Academic Press. This book was released on 2014-12-10 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides a broad perspective on tissue engineering for students coming to the subject for the first time. In addition to the key topics covered in the previous edition, this update also includes new material on the regulatory authorities, commercial considerations as well as new chapters on microfabrication, materiomics and cell/biomaterial interface. Effectively reviews major foundational topics in tissue engineering in a clear and accessible fashion Includes state of the art experiments presented in break-out boxes, chapter objectives, chapter summaries, and multiple choice questions to aid learning New edition contains material on regulatory authorities and commercial considerations in tissue engineering