Colorectal Cancer Liver Metastases

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Colorectal Cancer Liver Metastases

Author : Mauro Monteiro Correia
Publisher : Springer Nature
ISBN 13 : 3030254860
Total Pages : 597 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Colorectal Cancer Liver Metastases by : Mauro Monteiro Correia

Download or read book Colorectal Cancer Liver Metastases written by Mauro Monteiro Correia and published by Springer Nature. This book was released on 2019-12-28 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are better understood and more therapeutic and surgical options are developed. Consequently, all professionals involved with the diagnosis, treatment and follow up of CLM should be kept up to date with the latest advances on the field, to provide high standard medical care to their patients. This book is designed to present the state-of-the-art in CLM management and, in doing so, to review the current evidence on CLM, discussing all important topics in the field. Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.). Although comprehensive on the coverage and selection of topics, each chapter is concise and objective, dissecting topics in a practical and direct format. Evidences and recommendations are included. Chapters display a brief introduction of the common knowledge, go straight to the detailed revision of the most recent years of the literature, and end with practical closing observations. This book is a tool for professionals (general and cancer surgeons, HPB surgeons, clinical oncologists, gastroenterologists and medical residents) and interns who search for a qualified and reader friendly revision on topics concerning Colorectal Cancer Liver Metastases.

Colorectal Cancer Liver Metastases

Author : Mauro Monteiro Correia
Publisher : Springer
ISBN 13 : 9783030254889
Total Pages : 0 pages
Book Rating : 4.2/5 (548 download)

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Book Synopsis Colorectal Cancer Liver Metastases by : Mauro Monteiro Correia

Download or read book Colorectal Cancer Liver Metastases written by Mauro Monteiro Correia and published by Springer. This book was released on 2020-12-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are better understood and more therapeutic and surgical options are developed. Consequently, all professionals involved with the diagnosis, treatment and follow up of CLM should be kept up to date with the latest advances on the field, to provide high standard medical care to their patients. This book is designed to present the state-of-the-art in CLM management and, in doing so, to review the current evidence on CLM, discussing all important topics in the field. Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.). Although comprehensive on the coverage and selection of topics, each chapter is concise and objective, dissecting topics in a practical and direct format. Evidences and recommendations are included. Chapters display a brief introduction of the common knowledge, go straight to the detailed revision of the most recent years of the literature, and end with practical closing observations. This book is a tool for professionals (general and cancer surgeons, HPB surgeons, clinical oncologists, gastroenterologists and medical residents) and interns who search for a qualified and reader friendly revision on topics concerning Colorectal Cancer Liver Metastases.

Multidisciplinary Management of Liver Metastases in Colorectal Cancer

Author : Xinyu Qin
Publisher : Springer
ISBN 13 : 9401777551
Total Pages : 282 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Multidisciplinary Management of Liver Metastases in Colorectal Cancer by : Xinyu Qin

Download or read book Multidisciplinary Management of Liver Metastases in Colorectal Cancer written by Xinyu Qin and published by Springer. This book was released on 2016-12-12 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on early diagnosis and multidisciplinary treatment, which is the key to preventing the occurrence of the liver metastases in colorectal cancer, and to increasing the resection rate of the liver metastasis foci and the 5-year survival after surgery. This book is divided into five parts: the introduction, basics, diagnosis, treatment and prevention. It has 20 chapters in total, covering the latest advances in colorectal cancer liver metastases epidemiology, pathogenesis, molecular diagnostics, marker screening, imaging technology, surgery, chemotherapy and prevention, etc. It provides professionals with up-to-date and comprehensive information on colorectal liver metastases. This book is relevant for senior surgeons and physicians working in oncology, general surgery, chemotherapy, digestive medicine, liver medicine and hepatic surgery.

Perioperative Chemotherapy

Author : U. Metzger
Publisher : Springer Science & Business Media
ISBN 13 : 3642824323
Total Pages : 170 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Perioperative Chemotherapy by : U. Metzger

Download or read book Perioperative Chemotherapy written by U. Metzger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.

Holland-Frei Cancer Medicine

Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2004 pages
Book Rating : 4.1/5 (19 download)

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Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Colorectal Liver Metastasis

Author : Jean-Nicolas Vauthey
Publisher : Springer Nature
ISBN 13 : 3031093232
Total Pages : 552 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Colorectal Liver Metastasis by : Jean-Nicolas Vauthey

Download or read book Colorectal Liver Metastasis written by Jean-Nicolas Vauthey and published by Springer Nature. This book was released on 2022-11-24 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a practically applicable guide to the management of liver metastases in cases of colorectal cancer. It features detailed reviews of the latest diagnostic and therapeutic options. Instruction on how to appropriately apply surgical techniques including two stage hepatectomy as well as both laprascopic and open resection in a variety of scenarios is covered. The use of systemic therapies involving oxaliplatin, immunotherapy and infusional therapy are also described along with a range of surveillance strategies. Vauthey and Adam Colorectal Liver Metastasis comprehensively covers the latest advances in how to successfully diagnose and treat colorectal liver metastases and is an indispensable resource for all trainee and practicing medical professionals who encounter these patients within their clinical practice.

Metastasis of Colorectal Cancer

Author : Nicole Beauchemin
Publisher : Springer
ISBN 13 : 9789400732933
Total Pages : 416 pages
Book Rating : 4.7/5 (329 download)

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Book Synopsis Metastasis of Colorectal Cancer by : Nicole Beauchemin

Download or read book Metastasis of Colorectal Cancer written by Nicole Beauchemin and published by Springer. This book was released on 2012-10-13 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer is the third most common cancer worldwide, and in many parts of the western world, it is the second leading cause of cancer-related deaths. This book covers colon cancer metastasis from the most fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, cell adhesion, natures of liver metastasis, angiogenesis and lymphangiogenesis, inflammatory response, prognostic markers, sentinel node and staging, and finally diagnosis and treatment. Each chapter has been contributed by leaders in the field. A key feature is that it connects with a large readership including students, fundamentalists and clinicians. Another specific feature of the book is that the chapters are written in a didactic and illustrative fashion. These characteristics coupled with the choice of the topics and authors, makes this book a reference in the field. It represents an essential acquisition for medical libraries, clinicians as well as medical and graduate students.

Surgical Treatment of Colorectal Liver Metastases

Author : Lorenzo Capussotti
Publisher : Springer Science & Business Media
ISBN 13 : 8847018099
Total Pages : 192 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Surgical Treatment of Colorectal Liver Metastases by : Lorenzo Capussotti

Download or read book Surgical Treatment of Colorectal Liver Metastases written by Lorenzo Capussotti and published by Springer Science & Business Media. This book was released on 2011-01-27 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surgery is the gold standard treatment of colorectal liver metastases. Patients management had a dramatic evolution during the past years: more accurate diagnostic tools and more effective chemotherapy regimens have been introduced and surgical indications have been widely broadened. A multidisciplinary treatment is now mandatory, involving oncologists, radiologists an gastroenterologists. However, many topics are still debated. In the present book all aspects of surgical treatment of colorectal liver metastases are analyzed based on a systematic, updated analysis of the literature. Aim of this book is to provide surgeons, oncologists and radiologists a clear overview of the state-of-the-art of treatment of colorectal liver metastases.

Colon Polyps and Colorectal Cancer

Author : Omer Engin
Publisher : Springer Nature
ISBN 13 : 3030572730
Total Pages : 724 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Colon Polyps and Colorectal Cancer by : Omer Engin

Download or read book Colon Polyps and Colorectal Cancer written by Omer Engin and published by Springer Nature. This book was released on 2020-10-29 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thoroughly revised and extended second edition of the book clearly explains the nature of colon polyps and their relationship to colorectal cancer in light of new developments. It discusses in detail new topics, including polyp development, risk factors and prevention measures, and also describes surgical, medical oncology and radiotherapy treatments of colon cancer. In cases of advanced colon cancer, it clearly demonstrates how to perform surgical interventions in the presence of urinary tract metastases and gynecologic organ metastases. The book also includes chapters on medical treatment and radiotherapy in distant metastases of colorectal cancer. Further, it presents resection of liver metastases and transplantation options. Carefully examining the risk factors, and the treatment of colon cancer from the early to the advanced stages, the book is invaluable not only for medical specialists and students, but also for general readers and patients.

Liver Metastasis

Author : Cornelis Van de Velde
Publisher : Springer Science & Business Media
ISBN 13 : 9400960514
Total Pages : 398 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Liver Metastasis by : Cornelis Van de Velde

Download or read book Liver Metastasis written by Cornelis Van de Velde and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: B. CADY Hepatic met,,'~tasl~S present one of the major therapeutic challenges of cancer patien: management, for it is the destruction of vital organ function that makes cancer fatal, not local tumor growth. The process of tumor cell dislodgement from the primary cancer, their spread through the lymphatic and hematogenous channels, their lodgement in distant sites, and their subsequent progressive growth tax our comprehension a'ld i. -ustrate our therapies. The proceedings of this International Con,t ss on Hepatic Metastasis address these aspects of metastases to t:'. >2 _ . ver, and predominatly focus on metastatic colon cancer because of t ~. s frequency, its prominent hepatic only pattern of spread, and enticing preliminary data about prevention and control of small sub . '(ts of the afflicted population. Predictably, the "false technologies" of Dr. Lewis Thomas that involve surgical, radiotherapeutic and chemo therapeutic attack on these metastases after elaborate diagnostic studies take precedence because of the clinical imperatives of sick patients. This is displayed in the preponderance of papers and in terest in various diagnostic scanning techniques by means of radio isotopes, radiographically useful dyes, biochemical markers, interest in developing accurate staging systems to categorize patients for therapeutic comparisons, and interest in elaborate, and expensive, technology to increase the effectiveness of chemotherap~utic agents that are of limited benefit with simple intravenous administration. Behind this clinical enthusiasm, however, lies the research to develop the "true technology," in Thomas' words, that will prevent such clinical catastrophies as hepatic metastases.

Surgical Oncology Manual

Author : Frances C. Wright
Publisher : Springer Nature
ISBN 13 : 3030483630
Total Pages : 526 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Surgical Oncology Manual by : Frances C. Wright

Download or read book Surgical Oncology Manual written by Frances C. Wright and published by Springer Nature. This book was released on 2020-08-27 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition manual provides a comprehensive, insightful, evidenced-based review of general surgical oncology and serves as a valuable resource for general surgeons in training, practicing general surgeons, and surgical oncologists. The volume describes a multidisciplinary approach that integrates clinical, radiologic, and pathologic data in formulating practical clinical management, and offers a practical approach to the most common situations when treating cancer patients. Each chapter focuses on an individual malignancy and describes the presentation of the malignancy, integrated management based on stage, landmark trials, and suggestions for who to discuss at multidisciplinary cancer conferences. Multiple tables in each chapter provide a concise yet comprehensive summary of the current status of the field. Clinical “pearls” or tips and tricks from high volume surgeons at the University of Toronto are also discussed. The third edition of the Surgical Oncology Manual will serve as a critical resource for general surgeons in training and practicing surgeons dealing with this challenging field.

Extreme Hepatic Surgery and Other Strategies

Author : Eduardo de Santibañes
Publisher : Springer
ISBN 13 : 3319138960
Total Pages : 383 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Extreme Hepatic Surgery and Other Strategies by : Eduardo de Santibañes

Download or read book Extreme Hepatic Surgery and Other Strategies written by Eduardo de Santibañes and published by Springer. This book was released on 2017-07-26 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the diagnoses; staging and management of patients with colorectal liver metastases initially considered unresectable and portrays the different strategies to increase resectability along with their tactics and tricks. Colorectal carcinoma is the third most commonly diagnosed cancer in the world and according to recent cancer statistics around 1.23 million patients are diagnosed each year. Of these patients, approximately 50% will develop liver metastases during the course of their disease and around 15-25% are found to have stage IV disease at diagnosis. Liver resection has been recognized as the treatment of choice for these patients, offering overall 5-year survival rates of up to 50-60% and the only hope for cure. However, at diagnosis only 10-20% of these patients are possibly amenable to surgical resection with curative intent. The possibility to achieve an R0 resection is many times limited by the amount and quality of the future liver remnant (FLR), being posthepatectomy liver failure (PHLF) the most feared and severe complication after major liver resections. With the years, diverse strategies have been developed with the intention to increase resectability by increasing the future liver remnant and/or reducing tumor size, e.g. ALPPS. Along with these techniques, associated surgeries are developed including multivisceral resections, which broadens even more the resectability for patients.

Liver Metastases

Author : Jean-Nicolas` Vauthey
Publisher : Springer Science & Business Media
ISBN 13 : 1846289475
Total Pages : 191 pages
Book Rating : 4.8/5 (462 download)

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Book Synopsis Liver Metastases by : Jean-Nicolas` Vauthey

Download or read book Liver Metastases written by Jean-Nicolas` Vauthey and published by Springer Science & Business Media. This book was released on 2009-03-02 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the contemporary multidisciplinary management of liver metastases. Throughout the text, experience from the paradigms of colorectal cancer metastases treatment strategies are used to point to new directions in the management of liver metastases from other cancers. The book will be invaluable for surgeons in general surgery, hepatobiliary surgery, upper GI surgery, colorectal surgery, medical and clinical oncologists with an interest in liver tumours, and radiologists with an interest in liver disease.

Laser-induced Interstitial Thermotherapy

Author : Gerhard J. Müller
Publisher : SPIE Press
ISBN 13 : 9780819418593
Total Pages : 572 pages
Book Rating : 4.4/5 (185 download)

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Book Synopsis Laser-induced Interstitial Thermotherapy by : Gerhard J. Müller

Download or read book Laser-induced Interstitial Thermotherapy written by Gerhard J. Müller and published by SPIE Press. This book was released on 1995 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Liver Metastases

Author : R.A. Audisio
Publisher : Springer Science & Business Media
ISBN 13 : 1447115066
Total Pages : 337 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Liver Metastases by : R.A. Audisio

Download or read book Liver Metastases written by R.A. Audisio and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver Metastasis: Biology, Diagnosis and Treatment offers a comprehensive overview of liver metastasis by providing a collection of pivotal contributions from an international faculty. A wide range of topics are presented, with each contributor focusing on his own area of expertise to provide the latest techniques as well as valuable insights based on a wealth of experience. Epidemiological and biological aspects are discussed, diagnostic and staging problems are reported, and all treatment modalities are analysed including gene therapy, immunotherapy and palliative care. The standard approaches to diagnosis and therapy are examined whilst new and future trends are reported on and explored. Of interest to both specialists and postgraduates in the fields of oncology and gastroenterology this book will also be of interest to researchers in internal medicine.

Tumor Progression and Therapeutic Resistance

Author : Wafik S. El-Deiry
Publisher :
ISBN 13 :
Total Pages : 222 pages
Book Rating : 4.X/5 (3 download)

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Book Synopsis Tumor Progression and Therapeutic Resistance by : Wafik S. El-Deiry

Download or read book Tumor Progression and Therapeutic Resistance written by Wafik S. El-Deiry and published by . This book was released on 2005 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the entire breadth of translational cancer research and brings together members of academia and industry in the expectation of accelerating interactions and progress in the field. A variety of key topics are presented, beginning with discovery of molecular targets and pathways (oncogene, cell survival, tumor suppression, cell death), host-neoplasm interactions (cell adhesion, matrix proteases), early detection, monitoring progression, understanding tumor progression and metastasis, immune surveillance, in vivo molecular imaging, animal models, drug discovery including chemistry, high-throughput assays, mechanism determination, target validation, therapeutic window and some progress in clinical trials for more advanced agents and targets.

Image-Guided Interventions in Oncology

Author : Christos Georgiades
Publisher : Springer Nature
ISBN 13 : 3030487679
Total Pages : 397 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Image-Guided Interventions in Oncology by : Christos Georgiades

Download or read book Image-Guided Interventions in Oncology written by Christos Georgiades and published by Springer Nature. This book was released on 2020-07-28 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an up-to-date and comprehensive primer on image-guided interventions for cancer. Image-guided interventional oncology is gaining popularity as it is a minimally invasive and more precisely targeted approach that both proves more effective and results in fewer side effects. This book’s aim is to provide a clinical guide to interventional oncology for the entire oncology team. Chapters are approached with the same interdisciplinary perspective that is used in the care itself, with each chapter written by an interventional radiologist with contributions from medical, surgical and/or radiation oncologists. Chapters cover the major cancers that can benefit from interventional oncology treatment (including lung, liver, kidney, and bone), as well as some of the physics and physiology behind these interventional modalities. This is an ideal guide for interventional radiologists, medical oncologists, surgical oncologists, radiation oncologists, as well as relevant trainees.