Cholinesterases

Download Cholinesterases full books in PDF, epub, and Kindle. Read online Cholinesterases ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Cholinesterases and Anticholinesterase Agents

Author : George B. Koelle
Publisher : Springer Science & Business Media
ISBN 13 : 3642998755
Total Pages : 1228 pages
Book Rating : 4.6/5 (429 download)

DOWNLOAD NOW!

Book Synopsis Cholinesterases and Anticholinesterase Agents by : George B. Koelle

Download or read book Cholinesterases and Anticholinesterase Agents written by George B. Koelle and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 1228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the anticholinesterase (anti-ChE) agents have only limited applica tions in therapy, and from the viewpoint of practical significance they are more appropriately classified as toxic compounds or insecticides than as drugs, in their capacity of pharmacological tools they have few equals. The concept of neuro humoral transmission was originally established largely from experiments in which physostigmine, or eserine, was employed to protect acetylcholine (ACh), the trans mitter of the cholinergic nerves, from rapid hydrolytic destruction by acetyl cholinesterase (AChE) and other cholinesterases (ChE's). Since then, a great num ber of additional reversible and irreversible anti-ChE agents also have been indis pensable in studies of synaptic and neuroeffector transmission, and of other physiological processes. At the same time, there is practically no other class of compounds for which a mechanism of pharmacological action can be described in such concrete biochemical and physiological terms. Consequently, it is not sur prising that a huge literature has developed on these several closely interdependent topics. The assembling anrl proper correlation of this material for the present volume has taken the collaborative efforts of over two dozen . investigators. It iR believed that their contributions to this end will prove invaluable to future in vestigators in providing a ready, inclusive source of established information, in defining areas where further studies are indicated, and in preventing unnecessary duplication of past work. How well these aims have been accomplished will be for time and the reader to judge.

Cholinesterases and Cholinesterase Inhibitors

Author : Ezio Giacobini
Publisher : CRC Press
ISBN 13 : 9781853179105
Total Pages : 280 pages
Book Rating : 4.1/5 (791 download)

DOWNLOAD NOW!

Book Synopsis Cholinesterases and Cholinesterase Inhibitors by : Ezio Giacobini

Download or read book Cholinesterases and Cholinesterase Inhibitors written by Ezio Giacobini and published by CRC Press. This book was released on 2000-04-03 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the collaboration of the most distinguished scholars in this field Professor Giacobini has put together a publication which will convey present knowledge in the field of molecular biology and genetics, biochemistry, cell biology, pharmacology and toxicology as well of clinical applications (particularly in the field of Alzheimer's disease therapy) of cholinesterase inhibitors. In a concise but precise manner it condenses our present knowledge of these enzymes and their inhibitors and helps those who want to understand them as well as to utilize them for therapeutic purposes.

Enzymes of the Cholinesterase Family

Author : A.S. Balasubramanian
Publisher : Springer Science & Business Media
ISBN 13 : 1489910514
Total Pages : 524 pages
Book Rating : 4.4/5 (899 download)

DOWNLOAD NOW!

Book Synopsis Enzymes of the Cholinesterase Family by : A.S. Balasubramanian

Download or read book Enzymes of the Cholinesterase Family written by A.S. Balasubramanian and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fifth International Meeting on Cholinesterases convened in Madras, India, in September of 1994. The long and rich history and culture of India provided an excellent setting for the meeting. More than 120 delegates from Asia, Australia, Europe and North America heard 54 oral presentations and viewed 54 posters on current research on enzymes of the cholinesterase family. The aim of this book is to compile the presentations of the Fifth International Meeting on Cholinesterases into a volume that describes recent investigations on the structure and catalytic function of acetylcholinesterase (AChE), butyrylcholinesterase (BuChE) and related enzymes, as well as studies on the molecular and cellular biology of these enzymes and the genes which encode them. Cholinesterases enjoy a long and storied history in diverse areas. In basic biochemical research, AChE is one of the best studied, though yet enigmatic, of enzymes. The efficient catalytic function of this enzyme presents the biochemist with a fundamental challenge in understanding the relationship between structure and function. AChE and BuChE belong to a family of proteins, the alB hydrolase fold family, whose constituents evolutionarily diverged from a common ancestor. Proteins in this family have a wide range of physiological functions. In commerce, AChE is a prime target for agricultural insect control, and for the development of therapeutic agents for Alzheimer's disease.

The Biology of Cholinesterases

Author : Ann Silver
Publisher : North-Holland
ISBN 13 :
Total Pages : 620 pages
Book Rating : 4.X/5 (1 download)

DOWNLOAD NOW!

Book Synopsis The Biology of Cholinesterases by : Ann Silver

Download or read book The Biology of Cholinesterases written by Ann Silver and published by North-Holland. This book was released on 1974 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Structure and Function of Cholinesterases and Related Proteins

Author : Bhupendra P. Doctor
Publisher : Springer Science & Business Media
ISBN 13 : 1489915400
Total Pages : 627 pages
Book Rating : 4.4/5 (899 download)

DOWNLOAD NOW!

Book Synopsis Structure and Function of Cholinesterases and Related Proteins by : Bhupendra P. Doctor

Download or read book Structure and Function of Cholinesterases and Related Proteins written by Bhupendra P. Doctor and published by Springer Science & Business Media. This book was released on 2013-11-27 with total page 627 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Sixth International Meeting on Cholinesterases and Related Proteins, Choli nesterases '98, was organized by Palmer Taylor and his associates at the University of California-San Diego and convened in La Jolla, California, USA, in March of 1998. This was the first conference of the series to be held in the United States, let alone on the Pa cific Rim. Nearly 200 delegates from twenty countries-from Asia, Australia, Europe, and North and South America-heard 75 oral presentations and viewed 90 posters on current research on cholinesterases and related proteins. The meeting framework was structured to include two days of plenary sessions, followed by two days of concurrent sessions and workshops in specific areas. Communication at the concurrent sessions was facilitated by the conference settings of the Martin Johnson House, on a scenic bluff overlooking the blue Pacific Ocean, and the San Diego Supercomputer Center, which enabled projection and rotation of protein structures in three dimensions for a large audience. This book is the compilation of the presentations at the Sixth International Meeting on Cholinesterases and Related Proteins into a volume that describes recent investigations on the structure, catalytic and non-catalytic functions of acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and related proteins, as well as studies on the molecular and cellular biology of these enzymes and the genes that encode them.

Cholinesterases

Author : M. A. Gerebtzoff
Publisher : Elsevier
ISBN 13 : 148322127X
Total Pages : 205 pages
Book Rating : 4.4/5 (832 download)

DOWNLOAD NOW!

Book Synopsis Cholinesterases by : M. A. Gerebtzoff

Download or read book Cholinesterases written by M. A. Gerebtzoff and published by Elsevier. This book was released on 2013-10-22 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Trends in Physiological Sciences, Volume 3: Cholinesterases: A Histochemical Contribution to the Solution of Some Functional Problems covers the histochemical aspects of humoral and tissue cholinesterases, both inside and outside of the nervous system. This volume is composed of three part encompassing 14 chapters. The first part describes the link between cholinesterases and serum and between acetylcholinesterase and erythrocytes. This part also deals with the histochemical measurement of acetylcholinesterase activity in the erythrocytes or platelets of some mammalian species, with an emphasis on delineating the possible role of this enzyme in maintaining the integrity of these cells. The remaining two parts discuss the convergence of morphological, physiological, and biochemical research on tissue cholinesterases. These parts also describe the general features of the localization of cholinesterases at nerve-endings in tissues and organs. Histochemical investigations of tissular cholinesterases outside the nervous system, such as in smooth muscle fibers, are also presented. This book will be of value to physiologists, enzyme scientists and researchers, cell biologists, and histochemists.

Cholinesterases: Advances in Research and Application: 2011 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464925550
Total Pages : 182 pages
Book Rating : 4.4/5 (649 download)

DOWNLOAD NOW!

Book Synopsis Cholinesterases: Advances in Research and Application: 2011 Edition by :

Download or read book Cholinesterases: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cholinesterases: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cholinesterases. The editors have built Cholinesterases: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cholinesterases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cholinesterases: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Studies on the Storage Stability of Human Blood Cholinesterases, I

Author : Charles R. Crane
Publisher :
ISBN 13 :
Total Pages : 20 pages
Book Rating : 4.:/5 (89 download)

DOWNLOAD NOW!

Book Synopsis Studies on the Storage Stability of Human Blood Cholinesterases, I by : Charles R. Crane

Download or read book Studies on the Storage Stability of Human Blood Cholinesterases, I written by Charles R. Crane and published by . This book was released on 1970 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Human Cholinesterases and Anticholinesterases

Author : Hermona Soreq
Publisher : Academic Press
ISBN 13 : 0323155731
Total Pages : 331 pages
Book Rating : 4.3/5 (231 download)

DOWNLOAD NOW!

Book Synopsis Human Cholinesterases and Anticholinesterases by : Hermona Soreq

Download or read book Human Cholinesterases and Anticholinesterases written by Hermona Soreq and published by Academic Press. This book was released on 2012-12-02 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Cholinesterases and Anticholinesterases summarizes the many fundamental concepts of human cholinesterases (ChEs) and their inhibitors. This book is divided into three chapters that represent human cholinesterase research studies from different points of view. Chapter 1 deals with the biochemical and biological background of human ChEs. This chapter also examines the molecular polymorphism, genomic origin, genetic variants, and biological roles of these enzymes. Chapter 2 provides the molecular characterization of human ChE genes and their multileveled regulation, with a special emphasis on butyrylcholinesterase. Chapter 3 discusses the scientific, ecological, and clinical implications of the studies presented in the previous chapters. Protein scientists, engineers, and researchers will find this work invaluable.

Comparative Enzymology of Cholinesterases

Author : Serge N. Moralev
Publisher : Internat'l University Line
ISBN 13 : 9780972077422
Total Pages : 522 pages
Book Rating : 4.0/5 (774 download)

DOWNLOAD NOW!

Book Synopsis Comparative Enzymology of Cholinesterases by : Serge N. Moralev

Download or read book Comparative Enzymology of Cholinesterases written by Serge N. Moralev and published by Internat'l University Line. This book was released on 2007 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cholinesterases

Author : Jean Massoulié
Publisher :
ISBN 13 :
Total Pages : 440 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Cholinesterases by : Jean Massoulié

Download or read book Cholinesterases written by Jean Massoulié and published by . This book was released on 1991 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting the proceedings of the Third International Meeting on Cholinesterases, this volume provides a wealth of new information on current cholinesterase research and explores a number of avenues for future research. Important advances resulting from new concepts and methodologies such as monoclonal antibodies and molecular genetics, are covered. Among the topics covered in its 49 full papers and 140 poster papers are polymorphism and structure, cellular biology, gene structure and expression, agents, and noncholinergic roles of cholinesterases.

Cholinesterases—Advances in Research and Application: 2013 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481686585
Total Pages : 233 pages
Book Rating : 4.4/5 (816 download)

DOWNLOAD NOW!

Book Synopsis Cholinesterases—Advances in Research and Application: 2013 Edition by :

Download or read book Cholinesterases—Advances in Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cholinesterases—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Butyrylcholinesterase. The editors have built Cholinesterases—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Butyrylcholinesterase in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cholinesterases—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Acetylcholinesterase: Old Questions and New Developments

Author : Karl Tsim
Publisher : Frontiers E-books
ISBN 13 : 2889190986
Total Pages : 120 pages
Book Rating : 4.8/5 (891 download)

DOWNLOAD NOW!

Book Synopsis Acetylcholinesterase: Old Questions and New Developments by : Karl Tsim

Download or read book Acetylcholinesterase: Old Questions and New Developments written by Karl Tsim and published by Frontiers E-books. This book was released on with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acetylcholinesterase (AChE) is a primary regulator of cholinergic signaling within and out of the central nervous system. It has been studied extensively for several decades, yet many basic questions about its regulation, composition and functions remain open. Thus, neither the full impact of AChE’s activities on neuronal development, maintenance and functioning nor the reasons for why and how different AChE molecular forms are being synthesized and degraded are fully known yet, although recent evidence suggests the involvement of micro-RNA regulators in both of these aspects. The identification of the anchoring proteins, PRiMA and ColQ, stimulates studies on AChE’s assembly and its specific localization in the brain and muscle. Additionally, non-cholinergic function(s) of AChE has been proposed as relevant both for neuronal differentiation and cognitive functioning, whereas transgenic engineering, recombinant production and structure-function analyses of this enzyme’s variants with various inhibitors paved new avenues for the development of novel Alzheimer’s disease therapeutics, agricultural pesticides and prophylactics in anticipation of warfare agent exposure. The aims of this Research Topic is to provide a forum for experts in the field to critically discuss recent developments in AChE studies, initiate global critiques of the current views for resolving the fundamental questions in AChE research and promote the development of novel versions and uses of AChE-targeted agents. Topics of interest include but are not limited to: (i) post-transcriptional regulation of AChE; (ii) the non-cholinergic functions of AChE; and (iii) anti-AChE inhibitors and diseases.

Behavioral Pharmacology of the Cholinergic System

Author : Mohammed Shoaib
Publisher : Springer Nature
ISBN 13 : 3030560139
Total Pages : 245 pages
Book Rating : 4.0/5 (35 download)

DOWNLOAD NOW!

Book Synopsis Behavioral Pharmacology of the Cholinergic System by : Mohammed Shoaib

Download or read book Behavioral Pharmacology of the Cholinergic System written by Mohammed Shoaib and published by Springer Nature. This book was released on 2020-08-29 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: The molecular genetics of the cholinergic system including both muscarinic and nicotinic acetylcholine receptors, cholinesterases, acetylcholine synthesis and release have provided significant insights into potential targeting for pharmacological intervention. Cholinergic drugs are being used or evaluated for the treatment of diseases. Thus, this volume aims to broaden our understanding of the current state of cholinergic mechanisms to enable implementation of novel approaches for the development of more effective treatments.

Multidisciplinary Approaches to Cholinesterase Functions

Author : Avigdor Shafferman
Publisher : Springer Science & Business Media
ISBN 13 : 1461530466
Total Pages : 295 pages
Book Rating : 4.4/5 (615 download)

DOWNLOAD NOW!

Book Synopsis Multidisciplinary Approaches to Cholinesterase Functions by : Avigdor Shafferman

Download or read book Multidisciplinary Approaches to Cholinesterase Functions written by Avigdor Shafferman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cognitive Enhancing Drugs

Author : Jerry J. Buccafusco
Publisher : Birkhäuser
ISBN 13 : 3034878672
Total Pages : 213 pages
Book Rating : 4.0/5 (348 download)

DOWNLOAD NOW!

Book Synopsis Cognitive Enhancing Drugs by : Jerry J. Buccafusco

Download or read book Cognitive Enhancing Drugs written by Jerry J. Buccafusco and published by Birkhäuser. This book was released on 2012-12-06 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decade research into the pharmacology of cognition, particularly regarding learning and memory, has supported the concept that many potential neural targets exist for the development of cognitive-enhancing drugs. Whereas the main impetus for this research has been the ever growing population of individuals with dementing disorders such as Alzheimer`s disease, attention is also being focused on issues relating to cognitive impairment associated with "normal" aging. This book is useful as a source of information for making informed decisions regarding the relative utility and attributes of the various neural targets that have been studied to date.

Toxicology of Organophosphate and Carbamate Compounds

Author : Ramesh C Gupta
Publisher : Academic Press
ISBN 13 : 0080543103
Total Pages : 781 pages
Book Rating : 4.0/5 (85 download)

DOWNLOAD NOW!

Book Synopsis Toxicology of Organophosphate and Carbamate Compounds by : Ramesh C Gupta

Download or read book Toxicology of Organophosphate and Carbamate Compounds written by Ramesh C Gupta and published by Academic Press. This book was released on 2011-04-28 with total page 781 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. Describes everything you need to know about Organophosphates and Carbamates Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis Provides in vitro and in vivo models for neurotoxicity testing Integrates knowledge of studies in lab animals and humans Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues Describes management of Anticholinesterase poisoning in humans