Cerebral Blood Flow Measurements With Arterial Spin Labelling In A Tri Ethnic Population Cohort Associations Of Cardiovascular Risk Factors And Mr Imaging Markers Of Brain Ageing

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Cerebral Blood Flow Measurements with Arterial Spin Labelling in a Tri-ethnic Population Cohort

Author : Lorna A. Smith
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (116 download)

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Book Synopsis Cerebral Blood Flow Measurements with Arterial Spin Labelling in a Tri-ethnic Population Cohort by : Lorna A. Smith

Download or read book Cerebral Blood Flow Measurements with Arterial Spin Labelling in a Tri-ethnic Population Cohort written by Lorna A. Smith and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Differences in cerebral blood flow (CBF) have been identified between older individuals in good cognitive health and those experiencing cognitive decline and dementia. Previous studies have shown that the aetiology of dementia includes a substantial vascular component and there is evidence that CBF decline in old age may be linked to cardiovascular disease. Although the incidence, prevalence and impact of vascular risk varies by ethnicity and gender, many previous studies have focused on participants of white European origin or have pooled ethnically diverse samples, while differences between sexes have been under-investigated. This thesis used arterial spin labelling (ASL) to measure cortical CBF in an elderly tri-ethnic population cohort and examined its relationship with vascular risk and the brain ageing markers of cortical volume and white matter hyperintensity (WMH) volume from magnetic resonance imaging (MRI). Chapter 4 showed that use of the currently recommended mean haematocrit (Hct) value in equations that calculate CBF from ASL underestimated CBF in women and non-European ethnicities. The alternative method of substituting individually measured Hct into the equation was implemented in the following chapters. Results from Chapter 5 indicated that increased vascular risk factors were associated with lower CBF, but these relationships varied by ethnicity and sex. Ethnicity and sex also modified the strength of associations of increased vascular risk with decreased cortical tissue volume and increased volume of WMHs examined in Chapter 6. However, there was no evidence of any association of CBF with the MRI markers of brain ageing.

Measurement of Cerebral Blood Flow Using Arterial Spin Labeling Method Across Lifespan

Author : Ciwen Wang
Publisher :
ISBN 13 :
Total Pages : 74 pages
Book Rating : 4.:/5 (936 download)

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Book Synopsis Measurement of Cerebral Blood Flow Using Arterial Spin Labeling Method Across Lifespan by : Ciwen Wang

Download or read book Measurement of Cerebral Blood Flow Using Arterial Spin Labeling Method Across Lifespan written by Ciwen Wang and published by . This book was released on 2015 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arterial Spin Labeling (ASL) is one family of perfusion-weighted contrast imaging techniques of Magnetic Resonance Imaging (MRI) that measures cerebral blood flow by labeling spins in arterial blood with inversion and then waiting for a certain period of time for the labeled arterial blood to enter the imaging plane, and then acquiring MR image at the image plane. In compare with PET, ASL is a noninvasive new technology. But as a new technology, it is not very commonly used because of the relatively low signal to noise ratio, less robust mechanism, and more important, there is no standard for clinical applications. One goal of this study is to find out the optimal imaging processing way and parameters for ASL processing. The other goal is to find the relationship between CBF and age. There are 173 subjects, with 107 female subjects and 66 male subjects. Pseudo-continuous ASL (PCASL) was used as labeling sequence and multi-slice single shot 2D Echo-planar imaging (EPI) was used as MR image acquisition sequence. 40 pairs of control-labeled images were taken in order to increase signal to noise ratio. An MPRAGE T1 image was taken for each subject as brain structure reference. Label duration = 1650ms; post label delay = 1525ms; TR = 4260ms or 4210.8ms; TE=14ms. EPI factor = 35ms. Voxel size = 3x3x5 mm; FOV = 240x240x145 mm; slice number = 29. FSL which is a MRI image processing tool developed by Oxford was used in imaging processing. dcm2nii was used for DICOM to NIFTY conversion. MCFLIRT was used for motion correction. Trilinear interpolation was used in MCFLIRT. In spatial smoothing, a 3D Gaussian kernel with FWHM = 6mm was used. In M0 magnetization baseline calculation, the average magnetization of the whole brain of mean control image was used, so that the T1 recovery time was assumed to be the time from labeling to image acquisition of the middle slice (15th slice). The longitudinal relaxation time of blood was used as T1 value of the tissue. In Cerebral Blood Flow (CBF) calculation, also the longitudinal relaxation time of blood was used as T1 value of the tissue. A threshold of 0-300 was used on the CBF map. Voxels below 0 was assigned 0, and above 300 was assigned 300. CBF map was first co-registered on the T1 structural image of the same subject, and then, with the help of the high resolution T1, CBF map was normalized on MNI152 template. Relative CBF map was calculated by dividing the value of each voxel by the mean value of the whole brain CBF. The voxelwise analysis results (p

Textbook of Stroke Medicine

Author : Michael Brainin
Publisher : Cambridge University Press
ISBN 13 : 1107047498
Total Pages : 425 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Textbook of Stroke Medicine by : Michael Brainin

Download or read book Textbook of Stroke Medicine written by Michael Brainin and published by Cambridge University Press. This book was released on 2014-09-11 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised throughout, the new edition of this concise textbook is aimed at doctors preparing to specialize in stroke care.

Neuroimaging in Developmental Clinical Neuroscience

Author : Judith M. Rumsey
Publisher : Cambridge University Press
ISBN 13 : 1139476750
Total Pages : 473 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Neuroimaging in Developmental Clinical Neuroscience by : Judith M. Rumsey

Download or read book Neuroimaging in Developmental Clinical Neuroscience written by Judith M. Rumsey and published by Cambridge University Press. This book was released on 2009-02-19 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroimaging offers tremendous opportunities for gaining insights into normative development and a wide array of developmental neuropsychiatric disorders. Focusing on ontogeny, this text covers basic processes involved in both healthy and atypical maturation, and also addresses the range of neuroimaging techniques most widely used for studying children. This book will enable you to understand normative structural and functional brain maturation and the mechanisms underlying basic developmental processes; become familiar with current knowledge and hypotheses concerning the neural bases of developmental neuropsychiatric disorders; and learn about neuroimaging techniques, including their unique strengths and limitations. Coverage includes normal developmental processes, atypical processing in developmental neuropsychiatric disorders, ethical issues, neuroimaging techniques and their integration with psychopharmacologic and molecular genetic research approaches, and future directions. This comprehensive volume is an essential resource for neurologists, neuropsychologists, psychiatrists, pediatricians, and radiologists concerned with normal development and developmental neuropsychiatric disorders.

An Essay on the Shaking Palsy

Author : James Parkinson
Publisher :
ISBN 13 :
Total Pages : 86 pages
Book Rating : 4.A/5 ( download)

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Book Synopsis An Essay on the Shaking Palsy by : James Parkinson

Download or read book An Essay on the Shaking Palsy written by James Parkinson and published by . This book was released on 1817 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Developmental Neuroimaging

Author : Robert W. Thatcher
Publisher : Academic Press
ISBN 13 :
Total Pages : 358 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Developmental Neuroimaging by : Robert W. Thatcher

Download or read book Developmental Neuroimaging written by Robert W. Thatcher and published by Academic Press. This book was released on 1996-10-14 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examines the subject of neuroimaging of the human brain. This volume is divided into four sections: imaging of structural development; imaging of perceptual and cognitive development; imaging of abnormal development; and imaging of brain-behaviour relationships.

Textbook of Neurointensive Care

Author : A Joseph Layon
Publisher : Springer Science & Business Media
ISBN 13 : 1447152263
Total Pages : 982 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Textbook of Neurointensive Care by : A Joseph Layon

Download or read book Textbook of Neurointensive Care written by A Joseph Layon and published by Springer Science & Business Media. This book was released on 2013-08-15 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated and refined new edition is the only book to provide a comprehensive approach to the intensive care of neurologically injured patients from the emergency room and ICU through the operating room and post-surgical period. It reviews neuroanatomy, neuroradiology, and neurophysiology, examines the neurological problems most frequently seen in intensive care, and describes the various types of neurosurgery. General issues are discussed, such as cardiac care, fluids and electrolytes, nutrition, and monitoring as well as more specific conditions and complications including elevated intracranial pressure, seizures, and altered mental states.

The 71F Advantage

Author : National Defense University Press
Publisher : NDU Press
ISBN 13 : 1907521658
Total Pages : 529 pages
Book Rating : 4.9/5 (75 download)

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Book Synopsis The 71F Advantage by : National Defense University Press

Download or read book The 71F Advantage written by National Defense University Press and published by NDU Press. This book was released on 2010-09 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes a foreword by Major General David A. Rubenstein. From the editor: "71F, or "71 Foxtrot," is the AOC (area of concentration) code assigned by the U.S. Army to the specialty of Research Psychology. Qualifying as an Army research psychologist requires, first of all, a Ph.D. from a research (not clinical) intensive graduate psychology program. Due to their advanced education, research psychologists receive a direct commission as Army officers in the Medical Service Corps at the rank of captain. In terms of numbers, the 71F AOC is a small one, with only 25 to 30 officers serving in any given year. However, the 71F impact is much bigger than this small cadre suggests. Army research psychologists apply their extensive training and expertise in the science of psychology and social behavior toward understanding, preserving, and enhancing the health, well being, morale, and performance of Soldiers and military families. As is clear throughout the pages of this book, they do this in many ways and in many areas, but always with a scientific approach. This is the 71F advantage: applying the science of psychology to understand the human dimension, and developing programs, policies, and products to benefit the person in military operations. This book grew out of the April 2008 biennial conference of U.S. Army Research Psychologists, held in Bethesda, Maryland. This meeting was to be my last as Consultant to the Surgeon General for Research Psychology, and I thought it would be a good idea to publish proceedings, which had not been done before. As Consultant, I'd often wished for such a document to help explain to people what it is that Army Research Psychologists "do for a living." In addition to our core group of 71Fs, at the Bethesda 2008 meeting we had several brand-new members, and a number of distinguished retirees, the "grey-beards" of the 71F clan. Together with longtime 71F colleagues Ross Pastel and Mark Vaitkus, I also saw an unusual opportunity to capture some of the history of the Army Research Psychology specialty while providing a representative sample of current 71F research and activities. It seemed to us especially important to do this at a time when the operational demands on the Army and the total force were reaching unprecedented levels, with no sign of easing, and with the Army in turn relying more heavily on research psychology to inform its programs for protecting the health, well being, and performance of Soldiers and their families."

Pain Imaging

Author : Maria Assunta Cova
Publisher : Springer
ISBN 13 : 3319998226
Total Pages : 498 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis Pain Imaging by : Maria Assunta Cova

Download or read book Pain Imaging written by Maria Assunta Cova and published by Springer. This book was released on 2019-03-06 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses all pain imaging aspects related to both the central nervous system and the body (thorax, abdomen and pelvis), thus updating the international literature on the topic. By adopting a clinical-radiological approach and offering a comprehensive differential diagnosis for a number of painful syndromes (many of which can mimic one other), the work aims to support and enhance the diagnostic management of these patients, suggesting the most appropriate diagnostic algorithm. The book is divided into separate sections for each anatomical macro-area, and the chapters cover the respective topics from both clinical and radiological perspectives. Further, the book includes extensive electronic supplementary material. As such, it offers an invaluable tool for radiologists, neuroradiologists and clinicians working in internal medicine, surgery and neurology, and could also be used in residency programs for these groups.

Magnetic Resonance Imaging

Author : Robert W. Brown
Publisher : John Wiley & Sons
ISBN 13 : 0471720852
Total Pages : 976 pages
Book Rating : 4.4/5 (717 download)

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Book Synopsis Magnetic Resonance Imaging by : Robert W. Brown

Download or read book Magnetic Resonance Imaging written by Robert W. Brown and published by John Wiley & Sons. This book was released on 2014-06-23 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition explores contemporary MRI principles and practices Thoroughly revised, updated and expanded, the second edition of Magnetic Resonance Imaging: Physical Principles and Sequence Design remains the preeminent text in its field. Using consistent nomenclature and mathematical notations throughout all the chapters, this new edition carefully explains the physical principles of magnetic resonance imaging design and implementation. In addition, detailed figures and MR images enable readers to better grasp core concepts, methods, and applications. Magnetic Resonance Imaging, Second Edition begins with an introduction to fundamental principles, with coverage of magnetization, relaxation, quantum mechanics, signal detection and acquisition, Fourier imaging, image reconstruction, contrast, signal, and noise. The second part of the text explores MRI methods and applications, including fast imaging, water-fat separation, steady state gradient echo imaging, echo planar imaging, diffusion-weighted imaging, and induced magnetism. Lastly, the text discusses important hardware issues and parallel imaging. Readers familiar with the first edition will find much new material, including: New chapter dedicated to parallel imaging New sections examining off-resonance excitation principles, contrast optimization in fast steady-state incoherent imaging, and efficient lower-dimension analogues for discrete Fourier transforms in echo planar imaging applications Enhanced sections pertaining to Fourier transforms, filter effects on image resolution, and Bloch equation solutions when both rf pulse and slice select gradient fields are present Valuable improvements throughout with respect to equations, formulas, and text New and updated problems to test further the readers' grasp of core concepts Three appendices at the end of the text offer review material for basic electromagnetism and statistics as well as a list of acquisition parameters for the images in the book. Acclaimed by both students and instructors, the second edition of Magnetic Resonance Imaging offers the most comprehensive and approachable introduction to the physics and the applications of magnetic resonance imaging.

Posterior Circulation Disease

Author : Louis Caplan
Publisher : Wiley-Blackwell
ISBN 13 : 9780865422988
Total Pages : 728 pages
Book Rating : 4.4/5 (229 download)

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Book Synopsis Posterior Circulation Disease by : Louis Caplan

Download or read book Posterior Circulation Disease written by Louis Caplan and published by Wiley-Blackwell. This book was released on 1996-08-13 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: Posterior Circulation Disease is an authoritative, comprehensive, scholarly reference on vertebrobasilar disease. The book presents detailed descriptions of the anatomy and clinical correlations of the different stroke syndromes. The book begins with introductory chapters on anatomy and pathology, including a chapter devoted to evaluation. Later chapters discussing hemorrhage, aneurysm, and occlusion are divided according to location. Diagnosis, treatment and the general principles of imaging are also included to reflect the changing technology, (MRI, MRA) and transcranial Doppler. Posterior disease , (syncope and dizziness) is also fully discussed. The text emphasizes the clinical aspects of the disease and its management and includes discussions on the most advanced technology such as ultrasound, CT, angiography, PET and MRI.

Critical Findings in Neuroradiology

Author : Renato Hoffmann Nunes
Publisher : Springer
ISBN 13 : 3319279874
Total Pages : 516 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Critical Findings in Neuroradiology by : Renato Hoffmann Nunes

Download or read book Critical Findings in Neuroradiology written by Renato Hoffmann Nunes and published by Springer. This book was released on 2016-04-29 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides clear guidance as to which neuroradiological findings in ill or injured patients should be immediately communicated by radiologists and trainees to the emergency room and referring physicians in order to facilitate key decisions and eliminate preventable errors. It offers a practical and illustrative approach that identifies what to look for and how to report it and describes the required follow-up and the most common differential diagnoses of the main critical findings in neuroradiology. The book is distinctive in being written from a “critical findings perspective”, which makes its content more practical and memorable than that of a standard Emergency Neuroradiology textbook. It also illustrates the value of developing algorithmic approaches to report and communicate critical findings based on lists. While the book will appeal to a broad and variable audience, it is especially addressed to radiology training programs and will be a “must read” for residents and fellows in training.

Acute Perinatal Asphyxia in Term Infants

Author : Linda L. Wright
Publisher : DIANE Publishing
ISBN 13 : 9780788145445
Total Pages : 220 pages
Book Rating : 4.1/5 (454 download)

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Book Synopsis Acute Perinatal Asphyxia in Term Infants by : Linda L. Wright

Download or read book Acute Perinatal Asphyxia in Term Infants written by Linda L. Wright and published by DIANE Publishing. This book was released on 1997-07 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews the current knowledge of the definition & diagnosis of acute perinatal asphyxia in term infants in order to develop operational & specific criteria to be tested in new studies. Summarized information currently available on this topic. Contents: scientific basis of brain injury in acute perinatal asphyxia; clinical assessment -- obstetrics; clinical assessment -- neonatal; interventions (conventional management; neuronal rescue & neuronal prohylaxis; glutamate antagonists, calcium channel blockers & Allopurinol); clinical studies of long-term outcome; clinical research. Charts & tables.

Basketball Sports Medicine and Science

Author : Lior Laver
Publisher : Springer Nature
ISBN 13 : 3662610701
Total Pages : 1018 pages
Book Rating : 4.6/5 (626 download)

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Book Synopsis Basketball Sports Medicine and Science by : Lior Laver

Download or read book Basketball Sports Medicine and Science written by Lior Laver and published by Springer Nature. This book was released on 2020-10-05 with total page 1018 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as a comprehensive educational resource not only for basketball medical caregivers and scientists but for all basketball personnel. Written by a multidisciplinary team of leading experts in their fields, it provides information and guidance on injury prevention, injury management, and rehabilitation for physicians, physical therapists, athletic trainers, rehabilitation specialists, conditioning trainers, and coaches. All commonly encountered injuries and a variety of situations and scenarios specific to basketball are covered with the aid of more than 200 color photos and illustrations. Basketball Sports Medicine and Science is published in collaboration with ESSKA and will represent a superb, comprehensive educational resource. It is further hoped that the book will serve as a link between the different disciplines and modalities involved in basketball care, creating a common language and improving communication within the team staff and environment.

Drug Delivery to the Central Nervous System

Author : Kewal K. Jain
Publisher : Humana Press
ISBN 13 : 9781607615286
Total Pages : 0 pages
Book Rating : 4.6/5 (152 download)

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Book Synopsis Drug Delivery to the Central Nervous System by : Kewal K. Jain

Download or read book Drug Delivery to the Central Nervous System written by Kewal K. Jain and published by Humana Press. This book was released on 2009-12-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Playing an important role in the treatment of neurological disorders, the delivery of drugs to central nervous system (CNS), both administered directly and administered systematically for targeted action, encounters a major challenge in the form of the blood-brain barrier (BBB), which limits the access of drugs to the brain substance. In Drug Delivery to the Central Nervous System, experts in the field present essential methods used to deliver therapeutics across the BBB, both in experimental animals and in humans. In addition to those methods, several overviews of innovative methods and their applications are presented in order to give a glimpse of the future of this research. As a volume in the successful Neuromethods series, this book presents its protocols with the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and cutting-edge, Drug Delivery to the Central Nervous System serves as an ideal guide to scientists continuing to pursue knowledge of the delicate interactions between pharmaceuticals and the brain.

Stroke Nursing

Author : Jane Williams
Publisher : John Wiley & Sons
ISBN 13 : 1119111455
Total Pages : 407 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Stroke Nursing by : Jane Williams

Download or read book Stroke Nursing written by Jane Williams and published by John Wiley & Sons. This book was released on 2019-05-06 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke Nursing is the leading guide for optimal stroke care, facilitating the provision of evidence-based practice across the stroke journey, and covering the sixteen elements of care outlined in the UK's Stroke-Specific Education Framework (SSEF). Drawing from years of clinical and research experience, the authors provide practical guidance on the essential areas of stroke nursing, including stroke classification, stabilisation, thrombolysis and thrombectomy, rehabilitation and recovery, nutrition and oral care, palliative and long-term care, physical impairment management, and more. Now in its second edition, this indispensable guide helps practitioners expand their knowledge, skills and competence in all areas of stroke nursing services. Adopts a practical and evidence-based approach to stroke management, exploring UK and international perspectives Authored by expert clinicians and leaders in the field of nursing practice, research and education Includes updated case studies and practice examples, expanded coverage of clinical application in practice, and new discussions of the knowledge and skills required by nurses Stroke Nursing is essential reading for students of nursing and neuroscience, and is the definitive reference for practicing nurses and healthcare professionals caring for stroke patients.

Functional Neuroradiology

Author : Scott H. Faro
Publisher : Springer Science & Business Media
ISBN 13 : 1441903453
Total Pages : 1015 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Functional Neuroradiology by : Scott H. Faro

Download or read book Functional Neuroradiology written by Scott H. Faro and published by Springer Science & Business Media. This book was released on 2011-09-08 with total page 1015 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Neuroradiology: Principles and Clinical Applications, is a follow-up to Faro and Mohamed’s groundbreaking work, Functional (BOLD)MRI: Basic Principles and Clinical Applications. This new 49 chapter textbook is comprehensive and offers a complete introduction to the state-of-the-art functional imaging in Neuroradiology, including the physical principles and clinical applications of Diffusion, Perfusion, Permeability, MR spectroscopy, Positron Emission Tomography, BOLD fMRI and Diffusion Tensor Imaging. With chapters written by internationally distinguished neuroradiologists, neurologists, psychiatrists, cognitive neuroscientists, and physicists, Functional Neuroradiology is divided into 9 major sections, including: Physical principles of all key functional techniques, Lesion characterization using Diffusion, Perfusion, Permeability, MR spectroscopy, and Positron Emission Tomography, an overview of BOLD fMRI physical principles and key concepts, including scanning methodologies, experimental research design, data analysis, and functional connectivity, Eloquent Cortex and White matter localization using BOLD fMRI and Diffusion Tensor Imaging, Clinical applications of BOLD fMRI in Neurosurgery, Neurology, Psychiatry, Neuropsychology, and Neuropharmacology, Multi-modality functional Neuroradiology, Beyond Proton Imaging, Functional spine and CSF imaging, a full-color Neuroanatomical Brain atlas of eloquent cortex and key white matter tracts and BOLD fMRI paradigms. By offering readers a complete overview of functional imaging modalities and techniques currently used in patient diagnosis and management, as well as emerging technology, Functional Neuroradiology is a vital information source for physicians and cognitive neuroscientists involved in daily practice and research.