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Author : Frank Wehner
Publisher :
ISBN 13 : 9783928861373
Total Pages : 277 pages
Book Rating : 4.8/5 (613 download)
Download or read book Cell Biology and Molecular Basis of Liver Transport written by Frank Wehner and published by . This book was released on 1995 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cell Biology and Molecular Basis of Liver Transport written by and published by . This book was released on 1995 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Ernst Petzinger
Publisher :
ISBN 13 :
Total Pages : 14 pages
Book Rating : 4.:/5 (917 download)
Download or read book Cell biology and molecular basis of liver transport written by Ernst Petzinger and published by . This book was released on 1995 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Irwin M. Arias
Publisher : John Wiley & Sons
ISBN 13 : 1119436826
Total Pages : 1156 pages
Book Rating : 4.1/5 (194 download)
Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.
Author : Albert V. LeBouton
Publisher : CRC Press
ISBN 13 : 9780849388910
Total Pages : 582 pages
Book Rating : 4.3/5 (889 download)
Download or read book Molecular & Cell Biology of the Liver written by Albert V. LeBouton and published by CRC Press. This book was released on 1993-06-24 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular and Cell Biology of the Liver features the latest research findings regarding liver structure and function. A unique feature of the book is the brief science reviews that are included in each chapter which provide essential background information to allow readers to better grasp the subject matter within a chapter. The book covers liver biology from the molecular level to groups of liver cells and explains how groups of hepatocytes interact in similar microenvironments. Other important cell types found in the liver are also examined. Illustrations ranging from electron micrographs to fully rendered drawings act as visual aids to help readers understand complex structural-functional interactions. Molecular and Cell Biology of the Liver will benefit hepatologists, gastroenterologists, cell biologists, anatomists, toxicologists, and other researchers interested in liver structure and function.
Author : J. F. Woessner
Publisher : Elsevier
ISBN 13 : 1483220664
Total Pages : 343 pages
Book Rating : 4.4/5 (832 download)
Download or read book The Molecular Basis of Biological Transport written by J. F. Woessner and published by Elsevier. This book was released on 2013-10-22 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Miami Winter Symposia, Volume 3: The Molecular Basis of Biological Transport covers the proceedings of the symposium held in Miami on January 10-11, 1972. The book discusses the life of Feodor Lynen and his lecture on carbon dioxide fixation; the biochemical significance of the anion transporting systems of mitochondria, especially that of amino acid systems; and the possible functional roles of transport through membrane junctions. The text also describes the role of chlorotetracycline as a fluorescent chelate probe for monitoring Ca++ and Mg++ binding to biological membranes; and the effects of carcinogens and steroid hormones on the structural apparatus involved in protein synthesis and export. The nature and regulation of hexose uptake by Escherichia coli; the role of bacterial phosphotransferase system in sugar transport; and energy coupling to lactose transport in Escherichia coli are also considered. The book further tackles citrate transport by Bacillus subtilis; leucine transport in Escherichia coli; and the transport mechanism in isolated bacterial cytoplasmic membrane vesicles. Biochemists, microbiologists, pharmacologists, physiologists, and people involved in enzyme and metabolic research will find the book invaluable.
Author : Satdarshan P. S. Monga
Publisher : Springer Science & Business Media
ISBN 13 : 9781441971074
Total Pages : 919 pages
Book Rating : 4.9/5 (71 download)
Download or read book Molecular Pathology of Liver Diseases written by Satdarshan P. S. Monga and published by Springer Science & Business Media. This book was released on 2010-12-14 with total page 919 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular and Molecular Pathology of the Liver is extensive, complex and ranges from the understanding the basic molecular mechanisms that dictate everything from liver homeostasis to liver disease. Molecular Pathology of the liver is complicated due to some of the important functions inherent and unique to the Liver, including its innate ability to regenerate and the multitude of functions it plays for the wellbeing of an organism. With all this in mind, Molecular Pathology of Liver Diseases is organized in different sections, which will coherently and cohesively present the molecular basis of hepatic physiology and pathology. The first two sections are key to understanding the liver anatomy and physiology at a cellular level and go on to define the molecular mechanics in various liver cell types. These sections also cover the existing paradigms in liver development, regeneration and growth. The next section is key to understanding the Molecular Pathology unique to liver diseases and associated phenotypes. The final sections are geared towards the existing knowledge of the molecular basis of many common and uncommon liver diseases in both neoplastic and non-neoplastic areas including pathologies associated with intra-hepatic and extra-hepatic biliary tree. Thus, this textbook is a one-stop reference for comprehending the molecular mechanisms of hepatic pathobiology. It is clearly unique in its format, readability and information and thus will be an asset to many in the field of Pathology and other disciplines.
Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : John L. Gollan
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (596 download)
Download or read book The Molecular Basis of Hepatic Transport written by John L. Gollan and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Irwin M. Arias
Publisher : John Wiley & Sons
ISBN 13 : 1119436826
Total Pages : 1156 pages
Book Rating : 4.1/5 (194 download)
Download or read book The Liver written by Irwin M. Arias and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.
Author : S. Gupta
Publisher : Springer Science & Business Media
ISBN 13 : 9780792387763
Total Pages : 386 pages
Book Rating : 4.3/5 (877 download)
Download or read book Hepatocyte Transplantation written by S. Gupta and published by Springer Science & Business Media. This book was released on 2002-09-30 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years there has been an increasing need for transplantation, but the number of donor livers available has increased only slightly, despite intensive public relations activities. New concepts in the field of transplantation, for instance the transplantation of living donor organs or the splitting of organs, are urgently required, to safeguard the treatment of patients with severe liver disease. The development and clinical application of cell therapy for patients with liver disease could soon present a significant enhancement of the therapeutic options. The aim of such cell therapy is to repair or improve the biological function of the chronically and acutely damaged liver. Even though systematic trials are not available, individual case reports and small series already show promising clinical results. Present concepts of cell therapy for liver diseases based on the use of primary hepatocytes have recently been considerably extended through new data on the biology of stem cells. The adult haematopoetic stem cell as a pool for hepatocyte grafts - what would be the perspectives for the clinical application? This book is the proceedings of the Falk Symposium No. 126 on `Hepatocyte Transplantation' (Progress in Gastroenterology and Hepatology Part III) held in Hannover, Germany, October 2-3, 2001, and is a forum for basic research, but also for questions concerning clinical applications in the field of hepatocyte transplantation.
Author : Irwin M. Arias
Publisher : Lippincott Raven
ISBN 13 :
Total Pages : 1112 pages
Book Rating : 4.3/5 (91 download)
Download or read book The Liver written by Irwin M. Arias and published by Lippincott Raven. This book was released on 2001 with total page 1112 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first major text to link the discoveries of basic biology to the understanding and clinical management of liver diseases, The Liver: Biology and Pathobiology has long been a classic in gastroenterology and hepatology. Now, this landmark work has been thoroughly revised and updated to reflect recent groundbreaking achievements in the laboratory and clinic. More than 100 world-renowned investigators provide a definitive account of current concepts on the structure and function of the liver and the mechanisms underlying liver diseases. This edition has been pared down to a smaller, more user-friendly size and focused more sharply on the most important advances. A Brandon-Hill recommended title.
Author : Shay Soker
Publisher : Humana Press
ISBN 13 : 3319605119
Total Pages : 225 pages
Book Rating : 4.3/5 (196 download)
Download or read book Tumor Organoids written by Shay Soker and published by Humana Press. This book was released on 2017-10-20 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer cell biology research in general, and anti-cancer drug development specifically, still relies on standard cell culture techniques that place the cells in an unnatural environment. As a consequence, growing tumor cells in plastic dishes places a selective pressure that substantially alters their original molecular and phenotypic properties.The emerging field of regenerative medicine has developed bioengineered tissue platforms that can better mimic the structure and cellular heterogeneity of in vivo tissue, and are suitable for tumor bioengineering research. Microengineering technologies have resulted in advanced methods for creating and culturing 3-D human tissue. By encapsulating the respective cell type or combining several cell types to form tissues, these model organs can be viable for longer periods of time and are cultured to develop functional properties similar to native tissues. This approach recapitulates the dynamic role of cell–cell, cell–ECM, and mechanical interactions inside the tumor. Further incorporation of cells representative of the tumor stroma, such as endothelial cells (EC) and tumor fibroblasts, can mimic the in vivo tumor microenvironment. Collectively, bioengineered tumors create an important resource for the in vitro study of tumor growth in 3D including tumor biomechanics and the effects of anti-cancer drugs on 3D tumor tissue. These technologies have the potential to overcome current limitations to genetic and histological tumor classification and development of personalized therapies.
Author : Jong Hoon Park
Publisher : Springer
ISBN 13 : 9811020418
Total Pages : 128 pages
Book Rating : 4.8/5 (11 download)
Download or read book Cystogenesis written by Jong Hoon Park and published by Springer. This book was released on 2016-10-12 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.
Author : Samantha Fowler
Publisher :
ISBN 13 : 9789888407453
Total Pages : 618 pages
Book Rating : 4.4/5 (74 download)
Download or read book Concepts of Biology written by Samantha Fowler and published by . This book was released on 2018-01-07 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.
Author : Sebastian Mueller
Publisher : Springer Nature
ISBN 13 : 3030405427
Total Pages : 711 pages
Book Rating : 4.0/5 (34 download)
Download or read book Liver Elastography written by Sebastian Mueller and published by Springer Nature. This book was released on 2020-06-02 with total page 711 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive book on the new elastographic techniques discussing the early assessment of liver fibrosis. The book covers all aspects of measuring liver stiffness starting from the methodology, the molecular basis of liver stiffness elevation up to current clinical algorithms and interpretation. Future directions and novel implications that go beyond diagnosis but are relevant for understanding of liver cirrhosis per se are also discussed in detail. Liver Elastography, is an essential companion for hepatologists and gastroenterologists that provides an overview of its basic principles and gives a detailed account of how to use elastrography in clinical practice.
Author : Aparajita Dey
Publisher : Springer Science & Business Media
ISBN 13 : 9400758812
Total Pages : 269 pages
Book Rating : 4.4/5 (7 download)
Download or read book Cytochrome P450 2E1: Its Role in Disease and Drug Metabolism written by Aparajita Dey and published by Springer Science & Business Media. This book was released on 2013-02-12 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book deals with various clinical aspects of cytochrome P450 2E1 (CYP2E1) which is a potent source for oxidative stress. Oxidative stress is critical for pathogenesis of diseases and CYP2E1 is a major contributor for oxidative stress. Several clinical disorders are associated with changes in regulation of CYP2E1 and the consequent abnormalities which include alcoholic liver disease, alcoholic pancreatitis, carcinogenesis, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, obesity, hepatitis C virus infection, reproductive organ toxicity, hepatocellular and cholestatic liver cirrhosis, inhibition of bone repair, cross-tolerance in smokers and people treated with nicotine, disorders of central nervous system, changes in metabolism of protoxicants in the circulatory system and susceptibility to human papillomavirus infection. Hence, CYP2E1 emerges as a new and potent player in aggravating injury and furthering disease complications.
