Organic Synthesis with Carbohydrates

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Publisher : John Wiley & Sons
ISBN 13 : 0470760052
Total Pages : 348 pages
Book Rating : 4.4/5 (77 download)

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Book Synopsis Organic Synthesis with Carbohydrates by : Geert-Jan Boons

Download or read book Organic Synthesis with Carbohydrates written by Geert-Jan Boons and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrates offer a ready source of enantiomerically pure starting materials. They have been used for the imaginative synthesis of a wide range of compounds, and have been found to be effective chiral auxiliaries which enable the introduction of a range of functionalities in a highly enantioselective manner. In a subject dominated by volumes at research and professional level, this book provides a broad understanding of the use of carbohydrates in organic synthesis, at postgraduate student level. Emphasis is placed on retrosynthetic analysis, with discussion of why a particular synthetic route has been chosen, and mechanistic explanations are provided for key and novel reactions. Wherever possible, the authors highlight points of general significance to organic synthesis. Selected experimental conditions and reaction details are incorporated to ensure that information can be utilised in research. The book is extensively referenced and so provides a convenient point of entry to the primary literature.

Modern Methods in Carbohydrate Synthesis

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Author :
Publisher : CRC Press
ISBN 13 : 1000159485
Total Pages : 580 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Modern Methods in Carbohydrate Synthesis by : Shaheer H. Khan

Download or read book Modern Methods in Carbohydrate Synthesis written by Shaheer H. Khan and published by CRC Press. This book was released on 2020-08-26 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Methods in Carbohydrate Synthesis presents in one volume a sequence of chapters leading from classical methods through to today's newest state-of -the-art technology for oligosaccharide synthesis. It places particular emphasis on the most recent breakthroughs in the field, including emerging technologies for both oligosaccharide and glycoconjugate synthesis. Chapters describing the synthesis of increasingly important glycosidic linkage analogs, as well as the oligosaccharides containing derivatives and analogs of natural sugars are included. While chemical-synthetic methods constitute the major part of the book, completing the volume is a section on the rapidly expanding and important field of enzymatic synthesis, also covering combined chemical and enzymatic synthesis. Chapters are written by leading experts in the field. Wherever possible, methods of synthesis are provided in sufficient detail to allow the reader to implement the techniques described. More than 1700 references are provided in the 21 chapters comprising the book. This volume should provide a wealth of information to a large number of synthetic organic chemists, medicinal chemists, protein chemists, biochemists, glycobiologists and cell biologists, including students in these fields.

Carbohydrate Synthesis

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Author :
Publisher : American Chemical Society
ISBN 13 : 084129996X
Total Pages : 247 pages
Book Rating : 4.8/5 (412 download)

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Book Synopsis Carbohydrate Synthesis by : Clay S. Bennett

Download or read book Carbohydrate Synthesis written by Clay S. Bennett and published by American Chemical Society. This book was released on 2023-12-18 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approaching carbohydrate chemistry for the first time can be daunting as basic information is often buried in texts intended for advanced practitioners in the field. This brief primer attempts to bridge that gap. Chapter 1 introduces the basics of carbohydrate structure. Chapter 2 introduces the various roles carbohydrates play in biology. Chapter 3 discusses the glycosylation reaction used to assemble oligosaccharides along with a survey of commonly used glycosyl donors. Chapter 4 discusses commonly used protecting groups. Chapter 5 covers advances in automating the carbohydrate synthesis. Chapter 6 introduces the role of enzymes in the synthesis of homogeneous carbohydrates and glycoproteins. The authors hope this primer will introduce the uninitiated to the challenges and beauty of carbohydrate synthesis and inspire them to bring a new perspective and new advances to the field. Only by doing so will we, as a community of synthetic chemists, be able to tame one of the last and arguably most complex areas of chemical space to create new advances in human health.

Modern Synthetic Methods in Carbohydrate Chemistry

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527332847
Total Pages : 419 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Modern Synthetic Methods in Carbohydrate Chemistry by : Daniel B. Werz

Download or read book Modern Synthetic Methods in Carbohydrate Chemistry written by Daniel B. Werz and published by John Wiley & Sons. This book was released on 2013-12-23 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fields of glycochemistry and glycoscience are rich and varied and where much can be learned from Nature. As Nature is not always able to produce carbohydrates in quantities useful for not only in research but also as therapeutic agents, new ways need to be found to optimize the yield. This book presents an overview of the latest developments in the field of carbohydrates, ranging from de-novo approaches via cyclodextrin chemistry to the synthesis of such highly complex glycoconjugates as glycosphingolipids and GPI anchors. The main emphasis remains on the synthetic aspects making the book an excellent source of information for those already involved in carbohydrate chemistry, as well as for those organic chemists who are beginners in this field. Equally of interest to synthetic chemists, as well as medicinal chemists and biochemists.

Glycochemical Synthesis

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Publisher : John Wiley & Sons
ISBN 13 : 1118299841
Total Pages : 574 pages
Book Rating : 4.1/5 (182 download)

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Book Synopsis Glycochemical Synthesis by : Shang-Cheng Hung

Download or read book Glycochemical Synthesis written by Shang-Cheng Hung and published by John Wiley & Sons. This book was released on 2016-10-10 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive and concise review on principles, strategies, and crucial advances in glycochemistry. It focuses on synthesis and practical applications and emphasizes state-of-the-art approaches to the assembly and design of sugars. • Provides detailed discussion on specific topics like oligosaccharide assembly and design of sugars, techniques in glycoconjugate preparation, multivalency, and carbohydrate-based drug design • Uses notable examples, like solution-based one-pot methods and automated methods for sugar assembly, to illustrate important concepts and advances in a rapidly emerging field • Discusses practical applications of carbohydrates, like medicine, therapeutics, drug and vaccine development

Carbohydrates

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Author :
Publisher : Academic Press
ISBN 13 : 008052852X
Total Pages : 453 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Carbohydrates by : Helen Osborn

Download or read book Carbohydrates written by Helen Osborn and published by Academic Press. This book was released on 2003-04-22 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a vast and often bewildering array of synthetic methods and reagents available to organic chemists today. The Best Synthetic Methods series allows the practising synthetic chemist to choose between all the alternatives and assess their real advantages and limitations. Each chapter in Carbohydrates details a particular theme associated with carbohydrate synthesis. A brief review of the subject area is provided, but the emphasis in all cases is on describing efficient practical methods to effect the transformations described. In order for the roles of carbohydrates to be thoroughly analysed and assessed, glycobiologists require access to defined target carbohydrates in useful quantities. Thus carbohydrates and glycoconjugates are now recognized as important targets for total synthesis programmes and it is essential to develop efficient regio- and stereoselective methods for the synthesis of carbohydrates. Whilst carbohydrates can sometimes be isolated from natural sources, synthetic strategies often offer the advantage of allowing access to larger quantities of material as well as entry to analogues of the natural carbohydrates. The latest volume in the long standing Best Synthetic Methods series Clear chapter by chapter breakdown of carbohydrate synthesis themes with examples of good practical methods for common carbohydrate syntheses

Synthesis of Carbohydrates Through Biotechnology

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Author :
Publisher :
ISBN 13 :
Total Pages : 214 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Synthesis of Carbohydrates Through Biotechnology by : Peng George Wang

Download or read book Synthesis of Carbohydrates Through Biotechnology written by Peng George Wang and published by . This book was released on 2004 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Carbohydrates Through Biotechnology describes rapid developing and cutting-edge new technologies in glycoscience. These new approaches combine advantages of molecular biology, genetic engineering and chemistry, and provide access to synthetic carbohydrates.

Protecting-Group-Free Organic Synthesis

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1119295203
Total Pages : 283 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Protecting-Group-Free Organic Synthesis by : Rodney A. Fernandes

Download or read book Protecting-Group-Free Organic Synthesis written by Rodney A. Fernandes and published by John Wiley & Sons. This book was released on 2018-08-20 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a comprehensive account of established protecting-group-free synthetic routes to molecules of medium to high complexity This book supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an “ideal synthesis” and back the global need of practicing green chemistry. The only resource of its kind to focus entirely on protecting-group-free synthesis, it is edited by a leading practitioner in the field, and features enlightening contributions by top experts and researchers from across the globe. The introductory chapter includes a concise review of historical developments, and discusses the concepts, need for, and future prospects of protecting-group-free synthesis. Following this, the book presents information on protecting-group-free synthesis of complex natural products and analogues, heterocycles, drugs, and related pharmaceuticals. Later chapters discuss practicing protecting-group-free synthesis using carbohydrates and of glycosyl derivatives, glycol-polymers and glyco-conjugates. The book concludes with a chapter on latent functionality as a tactic toward formal protecting-group-free synthesis. A comprehensive account of established protecting-group-free (PGF) synthetic routes to molecules of medium to high complexity Benefits total synthesis, methodology development and drug synthesis researchers Supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an “ideal synthesis” and support the global need of practicing green chemistry Covers a topic that is gaining importance because it renders syntheses more economical Protecting-Group-Free Organic Synthesis: Improving Economy and Efficiency is an important book for academic researchers in synthetic organic chemistry, green chemistry, medicinal and pharmaceutical chemistry, biochemistry, and drug discovery.

The Organic Chemistry of Sugars

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Author :
Publisher : CRC Press
ISBN 13 : 1420027956
Total Pages : 904 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis The Organic Chemistry of Sugars by : Daniel E. Levy

Download or read book The Organic Chemistry of Sugars written by Daniel E. Levy and published by CRC Press. This book was released on 2005-09-21 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intrigued as much by its complex nature as by its outsider status in traditional organic chemistry, the editors of The Organic Chemistry of Sugars compile a groundbreaking resource in carbohydrate chemistry that illustrates the ease at which sugars can be manipulated in a variety of organic reactions. Each chapter contains numerous examples demonst

Carbohydrates

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Publisher : Springer Science & Business Media
ISBN 13 : 0387922652
Total Pages : 547 pages
Book Rating : 4.3/5 (879 download)

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Book Synopsis Carbohydrates by : Momcilo Miljkovic

Download or read book Carbohydrates written by Momcilo Miljkovic and published by Springer Science & Business Media. This book was released on 2009-09-18 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: All essential areas of basic synthetic carbohydrate chemistry are covered and appropriately described. In addition, this book explains the basic reaction mechanisms while taking into account modern concepts such as stereoelectronic principles.

Carbohydrate Chemistry

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Author :
Publisher : CRC Press
ISBN 13 : 1351646613
Total Pages : 439 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Carbohydrate Chemistry by : Christian Vogel

Download or read book Carbohydrate Chemistry written by Christian Vogel and published by CRC Press. This book was released on 2017-09-18 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volumes in the Proven Synthetic Methods Series address the concerns many chemists have regarding irreproducibility of synthetic protocols, lack of identification and characterization data for new compounds, and inflated yields reported in chemical communications—trends that have recently become a serious problem. Featuring contributions from world-renowned experts and overseen by a highly respected series editor, Carbohydrate Chemistry: Proven Synthetic Methods, Volume 4 compiles reliable synthetic methods and protocols for the preparation of intermediates for carbohydrate synthesis or other uses in the glycosciences. Exploring carbohydrate chemistry from both the academic and industrial points of view, this unique resource brings together useful information into one convenient reference. The series is unique among other synthetic literature in the carbohydrate field in that, to ensure reproducibility, an independent checker has verified the experimental parts involved by repeating the protocols or using the methods. The book includes new or more detailed versions of previously published protocols as well as those published in not readily available journals. The essential characteristics of the protocols presented are reliability, updated characterization data for newly synthesized substances and the expectation of wide utility in the carbohydrate field. The protocols presented will be of wide use to a broad range of readers in the carbohydrate field and the life sciences, including undergraduates taking carbohydrate workshops.

Enzymes in Carbohydrate Synthesis

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Author :
Publisher :
ISBN 13 :
Total Pages : 152 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Enzymes in Carbohydrate Synthesis by : Mark D. Bednarski

Download or read book Enzymes in Carbohydrate Synthesis written by Mark D. Bednarski and published by . This book was released on 1991 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Not only assessing the past, present, and future uses of enzymes to synthesize carbohydrates, this volume also illustrates the significance of carbohydrate chemistry and describes how the combination and use of modern enzyme chemistry can advance exploration in the field. Details research at the interface of chemistry and biology for carbohydrate chemistry by demonstrating how to integrate chemical reactions and biological techniques that can be used to synthesize complex bioactive monosaccharides, oligosaccarides, and glycoconjugates. Of particular interest are chapters by George Whitesides and Chi-Huey Wong covering the use of enzymes in monosaccharide synthesis, and Hindsgaul, Thiem, Nilsson, and Whitesides describing the use of activated sugar nucleosides and glycosyltransferases in the synthesis of oligosaccharides and polysaccharides.

Recent Trends in Carbohydrate Chemistry

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Author :
Publisher : Elsevier
ISBN 13 : 0128174676
Total Pages : 492 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Recent Trends in Carbohydrate Chemistry by : Amélia Pilar Rauter

Download or read book Recent Trends in Carbohydrate Chemistry written by Amélia Pilar Rauter and published by Elsevier. This book was released on 2020-05-13 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate chemistry provides access to carbohydrate-based natural products and synthetic molecules as useful biologically active structures relevant to many health care and disease-related biological processes. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates covers green and sustainable reactions, organometallic carbohydrate chemistry, synthesis of glycomimetics, multicomponent reactions, and chemical transformations leading to molecular diversity based on carbohydrates. These include inhibitors of glycogen phosphorylase, which are relevant in controlling type 2 diabetes and sugar sulfates. Polysaccharides, which are commonly modified chemically, are also examined with contributions covering polysaccharide synthesis and modification of polysaccharides to obtain new structures and properties. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates is ideal for researchers working as synthetic organic chemists, and for those interested in biomolecular chemistry, green chemistry, organometallic chemistry, and material chemistry in academia as well as in industry Demonstrates the importance of carbohydrate chemistry as green and sustainable chemistry Details monosaccharide syntheses and transformations toward biologically active small molecular entities Provides the most recent findings on polysaccharide synthesis and bioapplications

Carbohydrates

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Publisher : John Wiley & Sons
ISBN 13 : 3527654569
Total Pages : 386 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Carbohydrates by : Mike Martin Kwabena Boysen

Download or read book Carbohydrates written by Mike Martin Kwabena Boysen and published by John Wiley & Sons. This book was released on 2012-11-26 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Closing a gap in the literature, this comprehensive book presents the utility of carbohydrate derivatives as chiral auxiliaries, reagents, complex ligands and organocatalysts, together with details of their preparation, as well as their successful application in stereoselective synthesis. Divided into four parts: * Carbohydrate Auxiliaries * Carbohydrate Reagents * Carbohydrate Ligands * Carbohydrate Organocatalysts It is an indispensable source for every organic chemist.

Carbohydrate Chemistry: Chemical and Biological Approaches Volume 44

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1788013689
Total Pages : 307 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Carbohydrate Chemistry: Chemical and Biological Approaches Volume 44 by : Amelia Pilar Rauter

Download or read book Carbohydrate Chemistry: Chemical and Biological Approaches Volume 44 written by Amelia Pilar Rauter and published by Royal Society of Chemistry. This book was released on 2020-10-06 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrate Chemistry is an invaluable volume demonstrating the interdisciplinary nature of modern carbohydrate research and containing analysed, evaluated and distilled information on the latest research in the area.

Modern Methods in Carbohydrate Synthesis

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Author :
Publisher :
ISBN 13 : 9783178657856
Total Pages : 558 pages
Book Rating : 4.6/5 (578 download)

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Book Synopsis Modern Methods in Carbohydrate Synthesis by : Shaheer H. Khan

Download or read book Modern Methods in Carbohydrate Synthesis written by Shaheer H. Khan and published by . This book was released on 1996 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Carbohydrate Chemistry

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Author :
Publisher : CRC Press
ISBN 13 : 1498726925
Total Pages : 369 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Carbohydrate Chemistry by : Christian Vogel

Download or read book Carbohydrate Chemistry written by Christian Vogel and published by CRC Press. This book was released on 2017-09-18 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volumes in the Proven Synthetic Methods Series address the concerns many chemists have regarding irreproducibility of synthetic protocols, lack of identification and characterization data for new compounds, and inflated yields reported in chemical communications—trends that have recently become a serious problem. Featuring contributions from world-renowned experts and overseen by a highly respected series editor, Carbohydrate Chemistry: Proven Synthetic Methods, Volume 4 compiles reliable synthetic methods and protocols for the preparation of intermediates for carbohydrate synthesis or other uses in the glycosciences. Exploring carbohydrate chemistry from both the academic and industrial points of view, this unique resource brings together useful information into one convenient reference. The series is unique among other synthetic literature in the carbohydrate field in that, to ensure reproducibility, an independent checker has verified the experimental parts involved by repeating the protocols or using the methods. The book includes new or more detailed versions of previously published protocols as well as those published in not readily available journals. The essential characteristics of the protocols presented are reliability, updated characterization data for newly synthesized substances and the expectation of wide utility in the carbohydrate field. The protocols presented will be of wide use to a broad range of readers in the carbohydrate field and the life sciences, including undergraduates taking carbohydrate workshops.