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Cancer Virus Hunters
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Book Synopsis Cancer Virus Hunters by : Gregory J. Morgan
Download or read book Cancer Virus Hunters written by Gregory J. Morgan and published by JHU Press. This book was released on 2022-08-02 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traces the history of the study of tumor viruses and its role in driving breakthroughs in cancer research. Worldwide, approximately one-fifth of human cancers are caused by tumor viruses, with hepatitis B virus and HPV being the leading culprits. While the explosive growth in molecular biology in the late twentieth century is well known, the role that the study of tumor viruses has played in driving many of the greatest breakthroughs is not. Without the insights gained by studying tumor viruses, many significant theoretical advancements over the last four decades in cellular and molecular biology would not have been made. More practically, the study of tumor viruses has saved thousands, if not millions, of lives. In Cancer Virus Hunters, Gregory J. Morgan traces the high points in the development of tumor virology, from Peyton Rous's pioneering work on chicken tumors in 1909 to the successful development of an HPV vaccine for cervical cancer in 2006. Morgan offers a novel approach to understanding the interconnectedness of a long series of biomedical breakthroughs, including those that led to seven Nobel prizes. Among other advances, Morgan describes and contextualizes the science that prompted the discoveries of reverse transcriptase, RNA splicing, the tumor suppressor p53, the vaccine for hepatitis B, and the HIV test. He also explores how "cancer virus hunters" have demonstrated the virtue of beginning with a simple system, even when investigating a complex disease like cancer. Based on extensive archival research and over fifty interviews with experts, Cancer Virus Hunters is a tour de force summarizing a century of research to show how discoveries made with tumor viruses came to dominate the contemporary understanding of cancer. By showcasing the scientists themselves, the book makes for an unusually accessible journey through the history of science. It will be of interest to biomedical professionals—especially in oncology, hepatology, and infectious disease—in addition to historians of science and anyone interested in cancer research.
Book Synopsis A Contagious Cause by : Robin Wolfe Scheffler
Download or read book A Contagious Cause written by Robin Wolfe Scheffler and published by University of Chicago Press. This book was released on 2019-06-15 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Is cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer “germ,” inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent. ? A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government’s campaign merged the worlds of molecular biology, public health, and military planning in the name of translating laboratory discoveries into useful medical therapies. However, its expansion into biomedical research sparked fierce conflict. Many biologists dismissed the suggestion that research should be planned and the idea of curing cancer by a vaccine or any other means as unrealistic, if not dangerous. Although the American hunt was ultimately fruitless, this effort nonetheless profoundly shaped our understanding of life at its most fundamental levels. A Contagious Cause links laboratory and legislature as has rarely been done before, creating a new chapter in the histories of science and American politics.
Book Synopsis Cancer Virus Hunters by : Gregory J. Morgan
Download or read book Cancer Virus Hunters written by Gregory J. Morgan and published by JHU Press. This book was released on 2022-08-02 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The author tells a history of the study of cancer-causing viruses from the early twentieth century to the development of an HPV vaccine for cervical cancer in 2006. He profiles the "cancer virus hunters" who made breakthroughs in tumor virology"--
Download or read book Virus Hunters written by Greer Williams and published by . This book was released on 1959 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Viruses, Genes, and Cancer by : Eric Hunter
Download or read book Viruses, Genes, and Cancer written by Eric Hunter and published by Springer. This book was released on 2017-08-25 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes – such as oncogenes, proto-oncogenes, or tumor suppressor genes – in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. Gathering contributions written by leading scientists in their respective fields, the volume offers a valuable resource for researchers and clinicians alike.
Download or read book Virus Hunter written by Rick Emmer and published by Infobase Publishing. This book was released on 2006 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the history of deadly viruses, their effects on people, and the research of scientists to discover and develop treatments against them.
Book Synopsis Viruses and Human Cancer by : S. David Hudnall
Download or read book Viruses and Human Cancer written by S. David Hudnall and published by Springer. This book was released on 2014-06-21 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viruses and Human Cancer provides a comprehensive review of the seven currently known human tumor viruses and their associated cancers with an emphasis on epidemiology, clinicopathologic features, and pathogenesis. Chapters are written by internationally recognized experts and all are generously illustrated with tables, diagrams and photographic images. Viruses and Human Cancer is designed to serve as a concise review of the field of human tumor virology for pathologists, oncologists and infectious disease specialists. It will also be of great value to practicing physicians, residents and clinical fellows in these specialties.
Book Synopsis DNA Tumor Viruses by : Blossom Damania
Download or read book DNA Tumor Viruses written by Blossom Damania and published by Springer Science & Business Media. This book was released on 2008-12-19 with total page 805 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. This book represents a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover individual viruses that are also covered in this book, there is no single book that covers this topic comprehensively. This book is the first current, comprehensive review of its kind in the market.
Book Synopsis Cancer Associated Viruses by : Erle S. Robertson
Download or read book Cancer Associated Viruses written by Erle S. Robertson and published by Springer Science & Business Media. This book was released on 2012-02-14 with total page 869 pages. Available in PDF, EPUB and Kindle. Book excerpt: The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to the success of the human papilloma virus vaccine against invasive cervical carcinomas and followed by the awarding of the noble prize in medicine in 2008 to Dr. Harald zurHausen who identified the link between papilloma virus and cervical cancers. Over the last few years there have been some volumes addressing different aspects of viruses and cancers and to some extent focusing on the DNA viruses, more specifically the human DNA viruses. This proposed volume will attempt to review and address the major gaps in current knowledge in DNA viruses as well as RNA viruses bringing a historical perspective of where studies began to a more recent molecular approach and vaccine successes in tumor viruses. We will also cover other known oncogenic viruses associated cancers in other mammals in addition to humans.
Book Synopsis Cancer Associated Viruses by : Erle Robertson
Download or read book Cancer Associated Viruses written by Erle Robertson and published by Springer. This book was released on 2016-05-01 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume offers a comprehensive review of tumor virology. It examines the many aspects of cancer-related viruses and how they contribute to cell proliferation, the genes that are responsible for driving these cancers, and their mechanisms of transmission."
Book Synopsis Human Cancer Viruses by : John Nicholas
Download or read book Human Cancer Viruses written by John Nicholas and published by Karger Medical and Scientific Publishers. This book was released on 2008-01-01 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first identification of a tumor-causing virus, Rous sarcoma virus, occurred almost 100 years ago, but it was not until the 1970s that the genetic basis for oncogenesis by this and other acutely transforming retroviruses was appreciated. Since then, numerous viral oncogenes and their corresponding cellular proto-oncogene counterparts have been identified, and these studies have contributed much to our understanding of crucially important aspects of cell biology and transformation.This book provides an up-to-date overview of the 6 major viruses that cause human cancers - HPV, HBV, HCV, EBV, KSHV and HTLV-1 - with respect to their molecular biology and epidemiology and to clinical aspects of disease, therapy and prevention. Contributed by over a dozen internationally renowned scientists, the chapters are comprehensively written and illustrated. The book is suitable for advanced students, postdoctoral researchers, scientists and clinicians who wish to understand the mechanisms leading to cellular transformation and oncogenesis by these viruses as a basis for the development of specific therapeutic and antiviral treatments.
Book Synopsis The Virus Cancer Program by : National Cancer Institute (U.S.). Viral Oncology Program
Download or read book The Virus Cancer Program written by National Cancer Institute (U.S.). Viral Oncology Program and published by . This book was released on 1977 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Human Tumor Viruses by : Dennis J. McCance
Download or read book Human Tumor Viruses written by Dennis J. McCance and published by . This book was released on 1998 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: This valuable new book describes the molecular biology and pathogenesis of certain viruses linked with human cancers. It provides an up–to–date account of the progress in our knowledge of the virus/host interactions which lead to cancer, as well as insights on the complexity of virus/host interactions in general, most of which have yet to be delineated. The volume also offers an historical perspective of cancer viruses as well as an examination of the geographical distribution and prevalence of cancers. Human Tumor Viruses is essential reading for researchers and graduate students in virology, cell biology, pathology, and oncology and for anyone engaged in cancer research.
Download or read book Virus Hunting written by Robert C. Gallo and published by Basic Books. This book was released on 1993-08-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The renowned AIDS researcher Robert Gallo tells his story of scientific breakthrough in a riveting portrait of the people, the politics, and the pace of modern scientific discovery.
Book Synopsis The Virus Cancer Program by : National Cancer Institute (U.S.). Viral Oncology Program
Download or read book The Virus Cancer Program written by National Cancer Institute (U.S.). Viral Oncology Program and published by . This book was released on 1976 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Life Scientific: Virus Hunters by : Anna Buckley
Download or read book The Life Scientific: Virus Hunters written by Anna Buckley and published by Weidenfeld & Nicolson. This book was released on 2021-01-07 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: BBC Radio 4's celebrated THE LIFE SCIENTIFIC has featured some of the world's most renowned experts in the field of deadly viruses. The interviews make sobering reading, a reminder of all the deadly viruses that have threatened global health, and why for the scientists working on the front line in the war against viruses, the arrival of Covid-19 came as no surprise. Among the contributors to this all-too-timely book are: Jeremy Farrar, before he became Director of the Wellcome Trust, worked in an Infectious Diseases Hospital in Vietnam. He was on the frontline tackling SARS and nine months later a highly pathogenic strain of bird flu, H5N1. Peter Piot was at the forefront of the Ebola epidemic in West Africa. He was the first to identify HIV in Africa. It took him fifteen years to persuade the world that it was also a heterosexual disease. Later as Executive Director of UN AIDS he fought for years to get the UN to take the threat of HIV seriously. Jonathan Ball studies how viruses operate at the molecular level, hoping to find their Achilles' heel and so develop effective vaccines. During the West Africa Ebola epidemic, he studied how the genome of the Ebola virus evolved as it spread from Guinea to Liberia and Sierra Leone. He has shown that as this virus (which more happily lives in bats) infects more humans, it becomes ever more infectious. Wendy Barclay seeks to understand how viruses are able to jump from animals to humans and why some viruses are so much more dangerous to humans than others. Most Londoners had no idea they were infected during the Swine Flu pandemic of 2009. The Bird Flu epidemic in Asia claimed thousands of lives Kate Jones is a bat specialist who works on how ecological changes and human behaviour accelerate the spread of animal viruses into humans. Bats have been infected with coronaviruses for more than 10,000 years.
Download or read book The Virus Hunters written by Jane Qiu and published by . This book was released on 2023-03-30 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
