California Cures How The California Stem Cell Program Is Fighting Your Incurable Disease

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California Cures!: How The California Stem Cell Program Is Fighting Your Incurable Disease!

Author : Don C Reed
Publisher : World Scientific
ISBN 13 : 9813231386
Total Pages : 353 pages
Book Rating : 4.8/5 (132 download)

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Book Synopsis California Cures!: How The California Stem Cell Program Is Fighting Your Incurable Disease! by : Don C Reed

Download or read book California Cures!: How The California Stem Cell Program Is Fighting Your Incurable Disease! written by Don C Reed and published by World Scientific. This book was released on 2018-03-19 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'An engrossing read that is hard to put down and packed with insights blend history and the latest research with broader examination of stem cell potentials to change not only health conditions, but society as a whole. No collection covering stem cell advancements should be without this hard-hitting examination that uses California's results as a foundation for considering stem cell's special promises and powerful obstacles to success.'Midwestern Book ReviewThirteen years ago, America faced an epidemic of chronic disease: cancer, paralysis, blindness, arthritis, Alzheimer's disease, diabetes and more.But California voters said 'YES!' to a $3 billion stem cell research program: the awkwardly-named California Institute for Regenerative Medicine (CIRM). Born into battle, the scrappy little state agency was immediately blocked by three years of anti-science lawsuits — but it defeated them all. And then?A quiet triumph. With a focused intensity like the Manhattan Project (but for peaceful purposes, not to build a bomb), scientists funded by CIRM took on the challenges: disease and disability called chronic: incurable.In a series of connected stories, accurate though written to entertain, 'California Cures' relates a war: science against disease, with lives on the line. Think what it means for a paralyzed young man to recover the use of his hands, or for a formerly-blind mother to see her teenaged children — for the first time!Do you know the 'bubble-baby' syndrome? Infants without a proper immune system typically die young; a common cold can kill. But for eighteen babies in a stem cell clinical trial, a different future: they were cured of their disease.No one can predict the pace of science, nor say when cures will come; but California is bringing the fight. The reader will meet the scientists involved, the women and men behind the microscope, and share their struggle.Above all, 'California Cures' is a call for action. Washington may argue about the expense of health care (and who will get it), but California works to bring down the mountain of medical debt: stem cell therapies to ease suffering, and save lives.Will California build on success — and invest $5 billion more in stem cell research?'We have the momentum', says author Don C Reed, 'We dare not stop short. Chronic disease threatens everyone — we are fighting for your family, and mine!'

Science, Politics, Stem Cells And Genes: California's War On Chronic Disease

Author : Don C Reed
Publisher : World Scientific
ISBN 13 : 9811261431
Total Pages : 336 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Science, Politics, Stem Cells And Genes: California's War On Chronic Disease by : Don C Reed

Download or read book Science, Politics, Stem Cells And Genes: California's War On Chronic Disease written by Don C Reed and published by World Scientific. This book was released on 2023-02-13 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Is there a way to fight back against 'incurable' disease? California thought so — and put its money where its mind was — three billion dollars' worth! And when that was gone, how about five and a half billion dollars more — to build and expand the California Institute for Regenerative Medicine?For some, science excites; it is the great adventure, to challenge the impossible: like a real-life battle with a giant squid, or the proposed disassembly of the Eiffel Tower, or ejecting from a jet in the sky, from a height greater than Mount Everest.For others, regenerative medicine is a mystery — could the urge to do murder have a genetic cause — which might be reduced?And for everyone, there is the fight to protect our loved ones' lives— 133 million of us, suffering from chronic disease — from America alone, a colossal cost of $3 trillion dollars last year.An epic battle, 'Science, Politics, Stem Cells and Genes: CALIFORNIA'S WAR ON CHRONIC DISEASE' takes the reader behind the scenes.An award-winning teacher, Reed shares science in stories — including the systematic assault on Alzheimer's disease, cancer, autism, epilepsy, liver failure, schizophrenia, obesity, stroke, sickle cell, arthritis, blindness, paralysis, kidney failure, ALS, aging, and much, much more.Readers can expect a greater understanding of the intricate adventure of stem cell research, as well as the political wrestling it took to make progress possible — that California's effort may benefit the world.From early research to clinical trials, America should take pride in the accomplishments of the California Institute for Regenerative Medicine.Read on.

Revolutionary Therapies: How The California Stem Cell Program Saved Lives, Eased Suffering - And Changed The Face Of Medicine Forever

Author : Don C Reed
Publisher : World Scientific
ISBN 13 : 9811213305
Total Pages : 369 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Revolutionary Therapies: How The California Stem Cell Program Saved Lives, Eased Suffering - And Changed The Face Of Medicine Forever by : Don C Reed

Download or read book Revolutionary Therapies: How The California Stem Cell Program Saved Lives, Eased Suffering - And Changed The Face Of Medicine Forever written by Don C Reed and published by World Scientific. This book was released on 2020-03-04 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: For author Don C Reed, father of a paralyzed son, the California Institute for Regenerative Medicine (CIRM) is the greatest medical advance since penicillin.REVOLUTIONARY THERAPIES is Reed's third book about the $3 billion stem cell program.Voted into law in November 2004, CIRM is now running out of money.Should its funding be renewed? Thereby hangs a tale, or rather several dozen of them, for each of the book's 71 short chapters is framed by a yarn or vignette.The factual background is accurate, vetted by the scientists, but Reed's goal is clearly both entertainment and education.A favorite example is a little girl named Evie, imprisoned in a plastic bubble: her body's immune system did not work, and she would die outside. She joined a CIRM clinical trial ... Imagine how Evie's parents felt — when she got well.Some stories are comical, like 'How Stem Cell Research Saved My Car'; others surprising, like the comparison between politics and the giant crocodile Gustave; others are tragic or inspiring: but all point to this: More than 100 million Americans suffer chronic disease, causing mountains of medical debt — and the only way to reduce that expense ($3 trillion last year) — is cure.Related Link(s)

The California Institute for Regenerative Medicine

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309265932
Total Pages : 177 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis The California Institute for Regenerative Medicine by : Institute of Medicine

Download or read book The California Institute for Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2013-02-27 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: The California Institute for Regenerative Medicine (CIRM) was created in 2005 by The California Stem Cell Research and Cures Act (Proposition 71) to distribute $3 billion in state funds for stem cell research. The passage of Proposition 71 by the voters of California occurred at a time when federal funding for research involving human embryonic stem cells was uncertain, given the ethical questions raised by such research. During its initial period of operations, CIRM has successfully and thoughtfully provided more than $1.3 billion in awards to 59 California institutions, consistent with its stated mission. As it transitions to a broadened portfolio of grants to stimulate progress toward its translational goals, the Institute should obtain cohesive, longitudinal, and integrated advice; restructure its grant application review process; and enhance industry epresentation in aspects of its operations. CIRM's unique governance structure, while seful in its initial stages, might diminish its effectiveness moving forward. The California Institute for Regenerative Medicine: Science, Governance, and the Pursuit of Cures recommends specific steps to enhance CIRM's organization and management, as well as its scientific policies and processes, as it transitions to the critical next stages of its research and development program.

Stem Cells: From Hype To Hope

Author : Khawaja Husnain Haider
Publisher : World Scientific
ISBN 13 : 981120554X
Total Pages : 281 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Stem Cells: From Hype To Hope by : Khawaja Husnain Haider

Download or read book Stem Cells: From Hype To Hope written by Khawaja Husnain Haider and published by World Scientific. This book was released on 2020-03-19 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last two decades, stem cells have progressed from merely a concept to a vibrant field of regenerative medicine which is aimed at addressing the root cause of the problem rather than conventional methods of intervention that mostly provide symptomatic relief.Stem cell therapy either alone or in combination with the other established treatment strategies is a hope for patients who suffer from the 'incurable' diseases such as Alzheimer, diabetes, myocardial infarction etc. Besides aspirations in the clinical perspective, stem cells provide excellent in vitro disease models for drug development.Given the significance of the field, the proposed book will be a compilation of the bench experience of experts from various research labs involved in the cutting edge area of stem cell research.

Stem Cell Battles: Proposition 71 And Beyond - How Ordinary People Can Fight Back Against The Crushing Burden Of Chronic Disease - With A Posthumous Foreword By Christopher Reeve

Download Stem Cell Battles: Proposition 71 And Beyond - How Ordinary People Can Fight Back Against The Crushing Burden Of Chronic Disease - With A Posthumous Foreword By Christopher Reeve PDF Online Free

Author : Don C Reed
Publisher : World Scientific
ISBN 13 : 9814618292
Total Pages : 440 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Stem Cell Battles: Proposition 71 And Beyond - How Ordinary People Can Fight Back Against The Crushing Burden Of Chronic Disease - With A Posthumous Foreword By Christopher Reeve by : Don C Reed

Download or read book Stem Cell Battles: Proposition 71 And Beyond - How Ordinary People Can Fight Back Against The Crushing Burden Of Chronic Disease - With A Posthumous Foreword By Christopher Reeve written by Don C Reed and published by World Scientific. This book was released on 2015-10-06 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a one-of-a-kind book: combining easy-to-understand science, in-the-trenches political warfare, and inspirational stories. It aims to give hope to individuals and families who suffer from chronic disease or disability; to point out how ordinary people can make an extraordinary difference in the battle to ease suffering and save lives through supporting medical research; to share in “people talk” some of the amazing progress already achieved in the new field of stem cell research; to show how even such a magnificent success as the California stem cell program is under constant attack from ideological groups; to offer medical research as a force for international cooperation; to suggest how cure research lessens the need for the mountainous costs of endless care.Unparalleled background: the author has been involved in virtually every important stem cell battle (state, national, and international) since embryonic stem cell research began. The author works closely with Robert N. Klein, sponsor of the California stem cell program, the largest source of such stem cell research funding in the world. In addition, the author is an award-winning teacher as well as writer, and seeks to entertain as well as educate. His book is not only substantive, but also fun.The book would be a treasured gift: for anyone suffering an “incurable” illness or who is a caregiver for a loved one; for a college student considering a rewarding career in biomedicine; for scientists who want to protect and enhance their research funding; and for anyone who wants to see government respond to the needs of its citizenry. Chronic disease and disability are a prison: cure is the triumphant escape — wheelchairs should be for temporary occupancy only.

Exploring Novel Clinical Trial Designs for Gene-Based Therapies

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309672988
Total Pages : 127 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Exploring Novel Clinical Trial Designs for Gene-Based Therapies by : National Academies of Sciences, Engineering, and Medicine

Download or read book Exploring Novel Clinical Trial Designs for Gene-Based Therapies written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-08-27 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognizing the potential design complexities and ethical issues associated with clinical trials for gene therapies, the Forum on Regenerative Medicine of the National Academies of Sciences, Engineering, and Medicine held a 1-day workshop in Washington, DC, on November 13, 2019. Speakers at the workshop discussed patient recruitment and selection for gene-based clinical trials, explored how the safety of new therapies is assessed, reviewed the challenges involving dose escalation, and spoke about ethical issues such as informed consent and the role of clinicians in recommending trials as options to their patients. The workshop also included discussions of topics related to gene therapies in the context of other available and potentially curative treatments, such as bone marrow transplantation for hemoglobinopathies. This publication summarizes the presentation and discussion of the workshop.

Bugs as Drugs

Author : Robert A. Britton
Publisher : John Wiley & Sons
ISBN 13 : 1555819702
Total Pages : 514 pages
Book Rating : 4.5/5 (558 download)

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Book Synopsis Bugs as Drugs by : Robert A. Britton

Download or read book Bugs as Drugs written by Robert A. Britton and published by John Wiley & Sons. This book was released on 2020-07-02 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examining the enormous potential of microbiome manipulation to improve health Associations between the composition of the intestinal microbiome and many human diseases, including inflammatory bowel disease, cardiovascular disease, metabolic disorders, and cancer, have been elegantly described in the past decade. Now, whole-genome sequencing, bioinformatics, and precision gene-editing techniques are being combined with centuries-old therapies, such as fecal microbiota transplantation, to translate current research into new diagnostics and therapeutics to treat complex diseases. Bugs as Drugs provides a much-needed overview of microbes in therapies and will serve as an excellent resource for scientists and clinicians as they carry out research and clinical studies on investigating the roles the microbiota plays in health and disease. In Bugs as Drugs, editors Robert A. Britton and Patrice D. Cani have assembled a fascinating collection of reviews that chart the history, current efforts, and future prospects of using microorganisms to fight disease and improve health. Sections cover traditional uses of probiotics, next-generation microbial therapeutics, controlling infectious diseases, and indirect strategies for manipulating the host microbiome. Topics presented include: How well-established probiotics support and improve host health by improving the composition of the intestinal microbiota of the host and by modulating the host immune response. The use of gene editing and recombinant DNA techniques to create tailored probiotics and to characterize next-generation beneficial microbes. For example, engineering that improves the anti-inflammatory profile of probiotics can reduce the number of colonic polyps formed, and lactobacilli can be transformed into targeted delivery systems carrying therapeutic proteins or bioengineered bacteriophage. The association of specific microbiota composition with colorectal cancer, liver diseases, osteoporosis, and inflammatory bowel disease. The gut microbiota has been proposed to serve as an organ involved in regulation of inflammation, immune function, and energy homeostasis. Fecal microbiota transplantation as a promising treatment for numerous diseases beyond C. difficile infection. Practical considerations for using fecal microbiota transplantation are provided, while it is acknowledged that more high-quality evidence is needed to ascertain the importance of strain specificity in positive treatment outcomes. Because systems biology approaches and synthetic engineering of microbes are now high-throughput and cost-effective, a much wider range of therapeutic possibilities can be explored and vetted.

The Role of NIH in Drug Development Innovation and Its Impact on Patient Access

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309498511
Total Pages : 103 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis The Role of NIH in Drug Development Innovation and Its Impact on Patient Access by : National Academies of Sciences, Engineering, and Medicine

Download or read book The Role of NIH in Drug Development Innovation and Its Impact on Patient Access written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-01-27 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: To explore the role of the National Institutes of Health (NIH) in innovative drug development and its impact on patient access, the Board on Health Care Services and the Board on Health Sciences Policy of the National Academies jointly hosted a public workshop on July 24â€"25, 2019, in Washington, DC. Workshop speakers and participants discussed the ways in which federal investments in biomedical research are translated into innovative therapies and considered approaches to ensure that the public has affordable access to the resulting new drugs. This publication summarizes the presentations and discussions from the workshop.

Relieving Pain in America

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030921484X
Total Pages : 383 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Relieving Pain in America by : Institute of Medicine

Download or read book Relieving Pain in America written by Institute of Medicine and published by National Academies Press. This book was released on 2011-10-26 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic pain costs the nation up to $635 billion each year in medical treatment and lost productivity. The 2010 Patient Protection and Affordable Care Act required the Department of Health and Human Services (HHS) to enlist the Institute of Medicine (IOM) in examining pain as a public health problem. In this report, the IOM offers a blueprint for action in transforming prevention, care, education, and research, with the goal of providing relief for people with pain in America. To reach the vast multitude of people with various types of pain, the nation must adopt a population-level prevention and management strategy. The IOM recommends that HHS develop a comprehensive plan with specific goals, actions, and timeframes. Better data are needed to help shape efforts, especially on the groups of people currently underdiagnosed and undertreated, and the IOM encourages federal and state agencies and private organizations to accelerate the collection of data on pain incidence, prevalence, and treatments. Because pain varies from patient to patient, healthcare providers should increasingly aim at tailoring pain care to each person's experience, and self-management of pain should be promoted. In addition, because there are major gaps in knowledge about pain across health care and society alike, the IOM recommends that federal agencies and other stakeholders redesign education programs to bridge these gaps. Pain is a major driver for visits to physicians, a major reason for taking medications, a major cause of disability, and a key factor in quality of life and productivity. Given the burden of pain in human lives, dollars, and social consequences, relieving pain should be a national priority.

Encyclopedia of Stem Cell Research

Author :
Publisher : SAGE
ISBN 13 : 141295908X
Total Pages : 953 pages
Book Rating : 4.4/5 (129 download)

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Book Synopsis Encyclopedia of Stem Cell Research by :

Download or read book Encyclopedia of Stem Cell Research written by and published by SAGE. This book was released on 2008 with total page 953 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Provides an understanding of the basic concepts in stem cell biology and addresses the politics, ethics, and challenges currently facing the field"--From publisher description.

Flesh Made New

Author : John Rasko
Publisher : HarperCollins Australia
ISBN 13 : 1460711467
Total Pages : 285 pages
Book Rating : 4.4/5 (67 download)

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Book Synopsis Flesh Made New by : John Rasko

Download or read book Flesh Made New written by John Rasko and published by HarperCollins Australia. This book was released on 2021-02-01 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: The dazzling promise of stem cell medicine: does it work and will it save us? Two experts look at the hype For decades, we've been anticipating the dawn of regenerative medicine. Again and again, we've been promised that stem cells will soon cure just about every ill imaginable. If not tomorrow, then the next day, or the day after that, and so on. We're still waiting. This book is an antidote to hype and a salve to soothe the itch for stem-cell salvation. In it, Professor John Rasko, a leading physician-scientist, and writer-historian Carl Power take us on a wild historical tour of this scandal-prone field. They expose all the dirty little secrets that the hype merchants prefer to ignore - the blunders and setbacks, confusions and delusions, tricks and lies. You'll meet Alexis Carrel, who discovered how to cultivate cells in a test tube: celebrity surgeon, scientific genius and suspected Nazi sympathiser, he opened the field of modern cell science with an experiment so bogus it blocked the way forward for the next 50 years. You'll meet Don Thomas, who developed bone marrow transplantation - the first successful stem-cell therapy - but only after a miserable decade in which most of his patients died. Alongside true stem-cell pioneers, you'll meet charlatans who cooked their data and claimed fake cures - sometimes with fatal consequences. Is there any good news? Which of the many promises of stem-cell research have been kept? And what of the future? Rasko and Power insist that we can only know where we're going if we have a sense of where we've been. Their study tears down the hype surrounding stem cells in order to reveal what's still worth hoping for. PRAISE 'If you love some scandal with your science - or some science with your scandal - this is THE book for you. Brilliant stuff' Adam Spencer, University of Sydney 'Science, skulduggery and snake oil salesmen ... it is a revolution in medicine but who knew the story of stem cell science was such a ripping yarn!' Fran Kelly, ABC Radio National Breakfast 'Science isn't magic: it's a human enterprise. This enthralling book tells of high achievement and astonishing blunders in a vital field of research' Robyn Williams, science journalist and broadcaster 'A masterpiece in myth-busting which helps separate fact from fiction in the world of regenerative medicine. It shines a light on some episodes in medical history many would rather forget but also shows a way forward for stem cell research breakthroughs grounded in solid science' Sophie Scott, national medical reporter, ABC 'The stem cell revolution: myths, mistakes but mighty medical masterpiece' Sir Gustav Nossal, AC CBE FRS FAA, Australian of the Year 2000 'A compelling (and compulsory) read for anyone entranced by the latest media-promoted breakthroughs in medical research, or planning translation of new biomedical research into clinical practice' Ian Frazer, AC, FRCPE, FRCPA, FAA, FTSE Australian of the Year 2006, Australian Living Treasure 2012 'Is it really stem cells' turn to revolutionise health care? When you come across a train wreck, keep reading! You'll discover that stem cells reveal medicine in its most provocative and challenging light' Antony Basten AO FAA FTSE 'Flesh Made New is a revelation for the general reader about what lies beneath the surface of exciting scientific advances ... The book shows the value of patience and trust in robust evidence-based scientific research, and where things go off the rail, for whistleblowers and experts like the authors of this book' Lucy Turnbull AO, businesswoman, urbanist and philanthropist

Life Force

Author : Tony Robbins
Publisher : Simon and Schuster
ISBN 13 : 1982121734
Total Pages : 720 pages
Book Rating : 4.9/5 (821 download)

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Book Synopsis Life Force by : Tony Robbins

Download or read book Life Force written by Tony Robbins and published by Simon and Schuster. This book was released on 2022-02-08 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: INSTANT #1 NEW YORK TIMES BESTSELLER Transform your life or the life of someone you love with Life Force—the newest breakthroughs in health technology to help maximize your energy and strength, prevent disease, and extend your health span—from Tony Robbins, author of the #1 New York Times bestseller Money: Master the Game. What if there were scientific solutions that could wipe out your deepest fears of falling ill, receiving a life-threatening diagnosis, or feeling the effects of aging? What if you had access to the same cutting-edge tools and technology used by peak performers and the world’s greatest athletes? In a world full of fear and uncertainty about our health, it can be difficult to know where to turn for actionable advice you can trust. Today, leading scientists and doctors in the field of regenerative medicine are developing diagnostic tools and safe and effective therapies that can free you from fear. In this book, Tony Robbins, the world’s #1 life and business strategist who has coached more than fifty million people, brings you more than 100 of the world’s top medical minds and the latest research, inspiring comeback stories, and amazing advancements in precision medicine that you can apply today to help extend the length and quality of your life. This book is the result of Robbins going on his own life-changing journey. After being told that his health challenges were irreversible, he experienced firsthand how new regenerative technology not only helped him heal but made him stronger than ever before. Life Force will show you how you can wake up every day with increased energy, a more bulletproof immune system, and the know-how to help turn back your biological clock. This is a book for everyone, from peak performance athletes, to the average person who wants to increase their energy and strength, to those looking for healing. Life Force provides answers that can transform and even save your life, or that of someone you love.

Healing the Brain

Author : Curt Freed, M.D.
Publisher : Times Books
ISBN 13 : 9780805070910
Total Pages : 288 pages
Book Rating : 4.0/5 (79 download)

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Book Synopsis Healing the Brain by : Curt Freed, M.D.

Download or read book Healing the Brain written by Curt Freed, M.D. and published by Times Books. This book was released on 2002-06-12 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: In May 1995, neurologist Curt Freed began one of the most dramatic experiments in the history of medicine: the attempt to treat sufferers of Parkinson's disease by grafting human stem cells into their brains. Of the forty patients who volunteered for Freed's new treatment, half underwent authentic surgery. The other half, who had received placebo surgery, felt their last hope dissolve into bitter frustration. But the hardest road lay ahead for those who had been given the highly experimental procedure. Healing the Brain captures the emotional events that unfolded in the months afterward as Freed, his researchers, and their courageous, desperate patients awaited the outcome and witnessed a moral debate unfolding across the nation over embryonic stem-cell medicine. Would the brain regenerate itself or reject the new cells? This pioneering team was willing to take perilous risks to find out. Healing the Brain is a moving, fascinating narrative about discovery and disillusionment, conflict and compassion, suffering and -- for some -- amazing success.

Allogeneic Stem Cell Transplantation

Author : Hillard M. Lazarus
Publisher : Springer Science & Business Media
ISBN 13 : 1597454788
Total Pages : 885 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis Allogeneic Stem Cell Transplantation by : Hillard M. Lazarus

Download or read book Allogeneic Stem Cell Transplantation written by Hillard M. Lazarus and published by Springer Science & Business Media. This book was released on 2010-03-02 with total page 885 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.

Regenerative Medicine and Stem Cell Biology

Author : Nagwa El-Badri
Publisher : Springer Nature
ISBN 13 : 3030553590
Total Pages : 374 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Regenerative Medicine and Stem Cell Biology by : Nagwa El-Badri

Download or read book Regenerative Medicine and Stem Cell Biology written by Nagwa El-Badri and published by Springer Nature. This book was released on 2020-11-27 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers the basic aspects of stem cell research and applications in regenerative medicine. Each chapter includes a didactic component and a practical section. The book offers readers insights into: How to identify the basic concepts of stem cell biology and the molecular regulation of pluripotency and stem cell development. How to produce induced pluripotent stem cells (iPSCs) and the basics of transfection. The biology of adult stem cells, with particular emphasis on mesenchymal stromal cells and hematopoietic stem cells, and the basic mechanisms that regulate them. How cancer stem cells arise and metastasize, and their properties. How to develop the skills needed to isolate, differentiate and characterize adult stem The clinical significance of stem cell research and the potential problems that need to be overcome. Evaluating the use of stem cells for tissue engineering and therapies (the amniotic membrane) The applications of bio-nanotechnology in stem cell research. How epigenetic mechanisms, including various DNA modifications and histone dynamics, are involved in regulating the potentiality and differentiation of stem cells. The scientific methods, ethical considerations and implications of stem cell research.

The Emperor of All Maladies

Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
ISBN 13 : 1439170916
Total Pages : 624 pages
Book Rating : 4.4/5 (391 download)

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Book Synopsis The Emperor of All Maladies by : Siddhartha Mukherjee

Download or read book The Emperor of All Maladies written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2011-08-09 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.