The Brain-behavior Continuum

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Author :
Publisher : World Scientific
ISBN 13 : 981434060X
Total Pages : 370 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis The Brain-behavior Continuum by : Jose Luis Perez Velazquez

Download or read book The Brain-behavior Continuum written by Jose Luis Perez Velazquez and published by World Scientific. This book was released on 2011 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive overview of the main current concepts in brain cognitive activities at the global, collective (or network) level, with a focus on transitions between normal neurophysiology and brain pathological states. It provides a unique approach of linking molecular and cellular aspects of normal and pathological brain functioning with their corresponding network, collective and dynamical manifestations that are subsequently extended to behavioural manifestations of healthy and diseased brains. This book introduces a high-level perspective, searching for simplification amongst the structural and functional complexity of nervous systems by consideration of the distributed interactions that underlie the collective behaviour of the system. The authors hope that this approach could promote a global comprehensive understanding of high-level laws behind the elementary biological processes in the neuroscientific community, while, perhaps, introducing elements of biological complexities to the mathematical/computational readership. The title of the book refers to the main point of the monograph: that there is a smooth continuum between distinct brain activities resulting in different behaviours, and that, due to the plastic nature of the brain, the behaviour can also alter the brain function, thus rendering artificial the boundaries between the brain and its behaviour.

Brain-behavior Continuum, The: The Subtle Transition Between Sanity And Insanity

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Author :
Publisher : World Scientific Publishing Company
ISBN 13 : 9813108134
Total Pages : 372 pages
Book Rating : 4.8/5 (131 download)

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Book Synopsis Brain-behavior Continuum, The: The Subtle Transition Between Sanity And Insanity by : Perez-velazquez Jose Luis

Download or read book Brain-behavior Continuum, The: The Subtle Transition Between Sanity And Insanity written by Perez-velazquez Jose Luis and published by World Scientific Publishing Company. This book was released on 2011-06-10 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive overview of the main current concepts in brain cognitive activities at the global, collective (or network) level, with a focus on transitions between normal neurophysiology and brain pathological states. It provides a unique approach of linking molecular and cellular aspects of normal and pathological brain functioning with their corresponding network, collective and dynamical manifestations that are subsequently extended to behavioral manifestations of healthy and diseased brains. This book introduces a high-level perspective, searching for simplification amongst the structural and functional complexity of nervous systems by consideration of the distributed interactions that underlie the collective behavior of the system. The authors hope that this approach could promote a global comprehensive understanding of high-level laws behind the elementary biological processes in the neuroscientific community, while, perhaps, introducing elements of biological complexities to the mathematical/computational readership. The title of the book refers to the main point of the monograph: that there is a smooth continuum between distinct brain activities resulting in different behaviors, and that, due to the plastic nature of the brain, the behavior can also alter the brain function, thus rendering artificial the boundaries between the brain and its behavior.

Criticality as a signature of healthy neural systems: multi-scale experimental and computational studies

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889195031
Total Pages : 140 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Criticality as a signature of healthy neural systems: multi-scale experimental and computational studies by : Paolo Massobrio

Download or read book Criticality as a signature of healthy neural systems: multi-scale experimental and computational studies written by Paolo Massobrio and published by Frontiers Media SA. This book was released on 2015-05-08 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 2003, when spontaneous activity in cortical slices was first found to follow scale-free statistical distributions in size and duration, increasing experimental evidences and theoretical models have been reported in the literature supporting the emergence of evidence of scale invariance in the cortex. Although strongly debated, such results refer to many different in vitro and in vivo preparations (awake monkeys, anesthetized rats and cats, in vitro slices and dissociated cultures), suggesting that power law distributions and scale free correlations are a very general and robust feature of cortical activity that has been conserved across species as specific substrate for information storage, transmission and processing. Equally important is that the features reminiscent of scale invariance and criticality are observed at scale spanning from the level of interacting arrays of neurons all the way up to correlations across the entire brain. Thus, if we accept that the brain operates near a critical point, little is known about the causes and/or consequences of a loss of criticality and its relation with brain diseases (e.g. epilepsy). The study of how pathogenetical mechanisms are related to the critical/non-critical behavior of neuronal networks would likely provide new insights into the cellular and synaptic determinants of the emergence of critical-like dynamics and structures in neural systems. At the same time, the relation between the impaired behavior and the disruption of criticality would help clarify its role in normal brain function. The main objective of this Research Topic is to investigate the emergence/disruption of the emergent critical-like states in healthy/impaired neural systems.

Being and becoming

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Author :
Publisher : Springer Nature
ISBN 13 : 3030782646
Total Pages : 217 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Being and becoming by : Jose Luis Perez Velazquez

Download or read book Being and becoming written by Jose Luis Perez Velazquez and published by Springer Nature. This book was released on 2021-08-25 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many people spend considerable time seeking a sense of purpose in life and, concomitant with that, a sense of personal identity. This book demystifies this search, revealing why this search is a fallacy. The purpose is to inform readers about results in neuroscience and biophysics that may guide us to some liberation needed in the current age of great complexity in life with a diverse burden of chores; a deliverance from some afflictions that prevent individuals from achieving the true purpose of our lives. Among these afflictions we find two primordial concerns: the belief and subsequent attachment to a self, and the conviction that life must have a deep purpose in which we are major players. While this is a scientific text, it can easily be read by a lay audience, written with minimal technical jargon and with references to scientific papers enough to satisfy the curious. We have tried to extract the essence of scientific observations such that we can glimpse at those aforementioned concerns about the self and life, observations which help us comprehend what we are and what we become, the being and becoming of our own selves and natural phenomena around us. Jose Luis Perez Velazquez received a PhD in Molecular Physiology & Biophysics. His research seeks principles of biological organisation. He worked at the Hospital for Sick Children in Toronto and was Professor at the University of Toronto. Currently he is a Research Scholar at the Ronin Institute and lives in the natural paradise of Asturias, in Northern Spain. Vera Nenadovic is a nurse practitioner, neuroscientist and entrepreneur. She has 30 years of experience in healthcare from First Nations communities to intensive care units. Her research focuses on predicting brain injury outcomes. She is a clinician and researcher at Holland Bloorview Kids Rehab Hospital. Her startup company BrainsView is commercializing software that analyzes brainwaves to monitor brain function and recovery after head injury. She is married and lives in Toronto, with her husband and Rottweiler.

Information-based methods for neuroimaging: analyzing structure, function and dynamics

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889195023
Total Pages : 192 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Information-based methods for neuroimaging: analyzing structure, function and dynamics by : Jesus M. Cortés

Download or read book Information-based methods for neuroimaging: analyzing structure, function and dynamics written by Jesus M. Cortés and published by Frontiers Media SA. This book was released on 2015-05-07 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this Research Topic is to discuss the state of the art on the use of Information-based methods in the analysis of neuroimaging data. Information-based methods, typically built as extensions of the Shannon Entropy, are at the basis of model-free approaches which, being based on probability distributions rather than on specific expectations, can account for all possible non-linearities present in the data in a model-independent fashion. Mutual Information-like methods can also be applied on interacting dynamical variables described by time-series, thus addressing the uncertainty reduction (or information) in one variable by conditioning on another set of variables. In the last years, different Information-based methods have been shown to be flexible and powerful tools to analyze neuroimaging data, with a wide range of different methodologies, including formulations-based on bivariate vs multivariate representations, frequency vs time domains, etc. Apart from methodological issues, the information bit as a common unit represents a convenient way to open the road for comparison and integration between different measurements of neuroimaging data in three complementary contexts: Structural Connectivity, Dynamical (Functional and Effective) Connectivity, and Modelling of brain activity. Applications are ubiquitous, starting from resting state in healthy subjects to modulations of consciousness and other aspects of pathophysiology. Mutual Information-based methods have provided new insights about common-principles in brain organization, showing the existence of an active default network when the brain is at rest. It is not clear, however, how this default network is generated, the different modules are intra-interacting, or disappearing in the presence of stimulation. Some of these open-questions at the functional level might find their mechanisms on their structural correlates. A key question is the link between structure and function and the use of structural priors for the understanding of the functional connectivity measures. As effective connectivity is concerned, recently a common framework has been proposed for Transfer Entropy and Granger Causality, a well-established methodology originally based on autoregressive models. This framework can open the way to new theories and applications. This Research Topic brings together contributions from researchers from different backgrounds which are either developing new approaches, or applying existing methodologies to new data, and we hope it will set the basis for discussing the development and validation of new Information-based methodologies for the understanding of brain structure, function, and dynamics.

Gap Junctions in the Brain

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Publisher : Academic Press
ISBN 13 : 012415901X
Total Pages : 318 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Gap Junctions in the Brain by : Ekrem Dere

Download or read book Gap Junctions in the Brain written by Ekrem Dere and published by Academic Press. This book was released on 2012-08-30 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: In addition to chemical links across synapses, neurons can also form direct connections via electrical gap junctions. These channels play a key role in brain development and intercellular communication. Dere (pathophysiology of cerebral aging, U. Pierre et Marie Curie, Paris; AP-HP Hôpital Charles Foix, Centre de Recherche et Développement, Ivry-sur-Seine, France) introduces types of gap junctions, their structural aspects, expression patterns of connexins (transmembrane proteins), and gap junction-related diseases due to mutations in connexin genes. International researchers working in this emerging field discuss specific connexin genes and their mechanisms of action and function in the developing neocortx, behavior, and neurological and neuropsychiatric diseases. The text includes color and b&w illustrations including schematic representations and models. Academic Press is an imprint of Elsevier. Annotation ©2013 Book News, Inc., Portland, OR (booknews.com).

Neurobiology of Disease

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Publisher : Oxford University Press
ISBN 13 : 0199937834
Total Pages : 1435 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Neurobiology of Disease by : Michael V. Johnston

Download or read book Neurobiology of Disease written by Michael V. Johnston and published by Oxford University Press. This book was released on 2016 with total page 1435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preceded by Neurobiology of disease / edited by Sid Gilman. 2007.

The Origin of Consciousness in the Breakdown of the Bicameral Mind

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Publisher : Houghton Mifflin Harcourt
ISBN 13 : 0547527543
Total Pages : 580 pages
Book Rating : 4.5/5 (475 download)

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Book Synopsis The Origin of Consciousness in the Breakdown of the Bicameral Mind by : Julian Jaynes

Download or read book The Origin of Consciousness in the Breakdown of the Bicameral Mind written by Julian Jaynes and published by Houghton Mifflin Harcourt. This book was released on 2000-08-15 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: National Book Award Finalist: “This man’s ideas may be the most influential, not to say controversial, of the second half of the twentieth century.”—Columbus Dispatch At the heart of this classic, seminal book is Julian Jaynes's still-controversial thesis that human consciousness did not begin far back in animal evolution but instead is a learned process that came about only three thousand years ago and is still developing. The implications of this revolutionary scientific paradigm extend into virtually every aspect of our psychology, our history and culture, our religion—and indeed our future. “Don’t be put off by the academic title of Julian Jaynes’s The Origin of Consciousness in the Breakdown of the Bicameral Mind. Its prose is always lucid and often lyrical…he unfolds his case with the utmost intellectual rigor.”—The New York Times “When Julian Jaynes . . . speculates that until late in the twentieth millennium BC men had no consciousness but were automatically obeying the voices of the gods, we are astounded but compelled to follow this remarkable thesis.”—John Updike, The New Yorker “He is as startling as Freud was in The Interpretation of Dreams, and Jaynes is equally as adept at forcing a new view of known human behavior.”—American Journal of Psychiatry

EBOOK: A Sociology of Mental Health and Illness

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Author :
Publisher : McGraw-Hill Education (UK)
ISBN 13 : 0335262775
Total Pages : 290 pages
Book Rating : 4.3/5 (352 download)

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Book Synopsis EBOOK: A Sociology of Mental Health and Illness by : Anne Rogers

Download or read book EBOOK: A Sociology of Mental Health and Illness written by Anne Rogers and published by McGraw-Hill Education (UK). This book was released on 2014-05-16 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: How do we understand mental health problems in their social context? A former BMA Medical Book of the Year award winner, this book provides a sociological analysis of major areas of mental health and illness. The book considers contemporary and historical aspects of sociology, social psychiatry, policy and therapeutic law to help students develop an in-depth and critical approach to this complex subject.New developments for the fifth edition include: Brand new chapter on prisons, criminal justice and mental health Expanded coverage of stigma, class and social networks Updated material on the Mental Capacity Act, Mental Health Act and the Deprivation of Liberty A classic in its field, this well established textbook offers a rich and well-crafted overview of mental health and illness unrivalled by competitors and is essential reading for students and professionals studying a range of medical sociology and health-related courses. It is also highly suitable for trainee mental health workers in the fields of social work, nursing, clinical psychology and psychiatry. "Rogers and Pilgrim go from strength to strength! This fifth edition of their classic text is not only a sociology but also a psychology, a philosophy, a history and a polity. It combines rigorous scholarship with radical argument to produce incisive perspectives on the major contemporary questions concerning mental health and illness. The authors admirably balance judicious presentation of the range of available understandings with clear articulation of their own positions on key issues. This book is essential reading for everyone involved in mental health work." Christopher Dowrick, Professor of Primary Medical Care, University of Liverpool, UK "Pilgrim and Rogers have for the last twenty years given us the key text in the sociology of mental health and illness. Each edition has captured the multi-layered and ever changing landscape of theory and practice around psychiatry and mental health, providing an essential tool for teachers and researchers, and much loved by students for the dexterity in combining scope and accessibility. This latest volume, with its focus on community mental health, user movements criminal justice and the need for inter-agency working, alongside the more classical sociological critiques around social theories and social inequalities, demonstrates more than ever that sociological perspectives are crucial in the understanding and explanation of mental and emotional healthcare and practice, hence its audience extends across the related disciplines to everyone who is involved in this highly controversial and socially relevant arena." Gillian Bendelow, School of Law Politics and Sociology, University of Sussex, UK "From the classic bedrock studies to contemporary sociological perspectives on the current controversy over which scientific organizations will define diagnosis, Rogers and Pilgrim provide a comprehensive, readable and elegant overview of how social factors shape the onset and response to mental health and mental illness. Their sociological vision embraces historical, professional and socio-cultural context and processes as they shape the lives of those in the community and those who provide care; the organizations mandated to deliver services and those that have ended up becoming unsuitable substitutes; and the successful and unsuccessful efforts to improve the lives through science, challenge and law." Bernice Pescosolido, Distinguished Professor of Sociology, Indiana University, USA

Varcarolis' Foundations of Psychiatric Mental Health Nursing

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1455753580
Total Pages : 739 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Varcarolis' Foundations of Psychiatric Mental Health Nursing by : Margaret Jordan Halter

Download or read book Varcarolis' Foundations of Psychiatric Mental Health Nursing written by Margaret Jordan Halter and published by Elsevier Health Sciences. This book was released on 2014 with total page 739 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rev. ed. of: Foundations of psychiatric mental health nursing / [edited by] Elizabeth M. Varcarolis, Margaret Jordan Halter. 6th ed. c2010.

How to Change Your Mind

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Author :
Publisher : Penguin
ISBN 13 : 0735224153
Total Pages : 481 pages
Book Rating : 4.7/5 (352 download)

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Book Synopsis How to Change Your Mind by : Michael Pollan

Download or read book How to Change Your Mind written by Michael Pollan and published by Penguin. This book was released on 2019-05-14 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now on Netflix as a 4-part documentary series! “Pollan keeps you turning the pages . . . cleareyed and assured.” —New York Times A #1 New York Times Bestseller, New York Times Book Review 10 Best Books of 2018, and New York Times Notable Book A brilliant and brave investigation into the medical and scientific revolution taking place around psychedelic drugs--and the spellbinding story of his own life-changing psychedelic experiences When Michael Pollan set out to research how LSD and psilocybin (the active ingredient in magic mushrooms) are being used to provide relief to people suffering from difficult-to-treat conditions such as depression, addiction and anxiety, he did not intend to write what is undoubtedly his most personal book. But upon discovering how these remarkable substances are improving the lives not only of the mentally ill but also of healthy people coming to grips with the challenges of everyday life, he decided to explore the landscape of the mind in the first person as well as the third. Thus began a singular adventure into various altered states of consciousness, along with a dive deep into both the latest brain science and the thriving underground community of psychedelic therapists. Pollan sifts the historical record to separate the truth about these mysterious drugs from the myths that have surrounded them since the 1960s, when a handful of psychedelic evangelists inadvertently catalyzed a powerful backlash against what was then a promising field of research. A unique and elegant blend of science, memoir, travel writing, history, and medicine, How to Change Your Mind is a triumph of participatory journalism. By turns dazzling and edifying, it is the gripping account of a journey to an exciting and unexpected new frontier in our understanding of the mind, the self, and our place in the world. The true subject of Pollan's "mental travelogue" is not just psychedelic drugs but also the eternal puzzle of human consciousness and how, in a world that offers us both suffering and joy, we can do our best to be fully present and find meaning in our lives.

The Letters of Virginia Woolf

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Author :
Publisher :
ISBN 13 :
Total Pages : 638 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis The Letters of Virginia Woolf by : Virginia Woolf

Download or read book The Letters of Virginia Woolf written by Virginia Woolf and published by . This book was released on 1975 with total page 638 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Rethinking Madness

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Publisher : eBook Partnership
ISBN 13 : 0984986715
Total Pages : 295 pages
Book Rating : 4.9/5 (849 download)

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Book Synopsis Rethinking Madness by : Paris Williams

Download or read book Rethinking Madness written by Paris Williams and published by eBook Partnership. This book was released on 2014-06-19 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the research continues to accumulate, we find that the mainstream understanding of schizophrenia and the other related psychotic disorders has lost virtually all credibility. We've learned that full recovery is not only possible, but may actually be the most common outcome given the right conditions. Furthermore, Dr. Paris Williams' own groundbreaking research, as mentioned in the New York Times, has shown that recovery often entails a profound positive transformation. In Rethinking Madness, Dr. Williams takes the reader step by step on a highly engaging journey of discovery, exploring how the mainstream understanding of schizophrenia has become so profoundly misguided, while crafting a much more accurate and hopeful vision. As this vision unfolds, we discover a deeper sense of appreciation for the profound wisdom and resilience that lies within all of our beings, even those we may think of as being deeply disturbed, while also coming to the unsettling realization of just how thin the boundary is between so called madness and so called sanity.

Textbook of Epilepsy Surgery

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Publisher : CRC Press
ISBN 13 : 0203091701
Total Pages : 1624 pages
Book Rating : 4.2/5 (3 download)

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Book Synopsis Textbook of Epilepsy Surgery by : Hans O. Luders

Download or read book Textbook of Epilepsy Surgery written by Hans O. Luders and published by CRC Press. This book was released on 2008-07-11 with total page 1624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook of Epilepsy Surgery covers all of the latest advances in the surgical management of epilepsy. The book provides a thorough understanding of epileptogenic mechanisms in etiologically different types of epilepsy and explains neuronavigation systems. It discusses new neuroimaging techniques, new surgical strategies, and more aggressive surgic

The Making of Modern Psychiatry

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Publisher : Logos Verlag Berlin GmbH
ISBN 13 : 3832547185
Total Pages : 232 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis The Making of Modern Psychiatry by : Ronald Chase

Download or read book The Making of Modern Psychiatry written by Ronald Chase and published by Logos Verlag Berlin GmbH. This book was released on 2018 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of psychiatry changed dramatically in the latter half of the nineteenth century, largely by embracing science. The transformation was most evident in Germany, where many psychiatrists began to work concurrently in the clinic and the laboratory. Some researchers sought to discover brain correlates of mental illness, while others looked to experimental psychology for insights into mental dynamics. Featured here, are the lives and works of Emil Kraepelin - often considered the founder of modern scientific psychiatry, his teacher Bernhard Gudden, and his anatomist colleague Franz Nissl. The book describes scientific findings together with the methods used; it explains why diagnoses were then (and are still now) so difficult to make; it also explores mind-brain controversies. The Making of Modern Psychiatry will inform and delight mental health professionals as well as all persons curious about the origins of modern psychiatry. ``Ronald Chase has provided fascinating information about the 19th century scientists' thinking on behavioral disorders: how to identify them, how to treat them, how to understand them ... He is a terrific writer and has compiled very interesting stories that bring to life the thinking of the time and the condition of serious mental illnesses in their first stages of understanding ... The author weaves the work of the 20th to 21st centuries nicely into his story ... gives optimism for a brain-based understanding in the future.'' Carol Tamminga, M.D. Professor and Chair, Department of Psychiatry, University of Texas Southwestern Medical Center

The Divided Self

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Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (681 download)

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Book Synopsis The Divided Self by : Ronald David Laing

Download or read book The Divided Self written by Ronald David Laing and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Cognitive-Theoretic Model of the Universe: A New Kind of Reality Theory

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Author :
Publisher : Mega Foundation Press
ISBN 13 : 0971916225
Total Pages : 94 pages
Book Rating : 4.9/5 (719 download)

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Book Synopsis The Cognitive-Theoretic Model of the Universe: A New Kind of Reality Theory by : Christopher Michael Langan

Download or read book The Cognitive-Theoretic Model of the Universe: A New Kind of Reality Theory written by Christopher Michael Langan and published by Mega Foundation Press. This book was released on 2002-06-01 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paperback version of the 2002 paper published in the journal Progress in Information, Complexity, and Design (PCID). ABSTRACT Inasmuch as science is observational or perceptual in nature, the goal of providing a scientific model and mechanism for the evolution of complex systems ultimately requires a supporting theory of reality of which perception itself is the model (or theory-to-universe mapping). Where information is the abstract currency of perception, such a theory must incorporate the theory of information while extending the information concept to incorporate reflexive self-processing in order to achieve an intrinsic (self-contained) description of reality. This extension is associated with a limiting formulation of model theory identifying mental and physical reality, resulting in a reflexively self-generating, self-modeling theory of reality identical to its universe on the syntactic level. By the nature of its derivation, this theory, the Cognitive Theoretic Model of the Universe or CTMU, can be regarded as a supertautological reality-theoretic extension of logic. Uniting the theory of reality with an advanced form of computational language theory, the CTMU describes reality as a Self Configuring Self-Processing Language or SCSPL, a reflexive intrinsic language characterized not only by self-reference and recursive self-definition, but full self-configuration and self-execution (reflexive read-write functionality). SCSPL reality embodies a dual-aspect monism consisting of infocognition, self-transducing information residing in self-recognizing SCSPL elements called syntactic operators. The CTMU identifies itself with the structure of these operators and thus with the distributive syntax of its self-modeling SCSPL universe, including the reflexive grammar by which the universe refines itself from unbound telesis or UBT, a primordial realm of infocognitive potential free of informational constraint. Under the guidance of a limiting (intrinsic) form of anthropic principle called the Telic Principle, SCSPL evolves by telic recursion, jointly configuring syntax and state while maximizing a generalized self-selection parameter and adjusting on the fly to freely-changing internal conditions. SCSPL relates space, time and object by means of conspansive duality and conspansion, an SCSPL-grammatical process featuring an alternation between dual phases of existence associated with design and actualization and related to the familiar wave-particle duality of quantum mechanics. By distributing the design phase of reality over the actualization phase, conspansive spacetime also provides a distributed mechanism for Intelligent Design, adjoining to the restrictive principle of natural selection a basic means of generating information and complexity. Addressing physical evolution on not only the biological but cosmic level, the CTMU addresses the most evident deficiencies and paradoxes associated with conventional discrete and continuum models of reality, including temporal directionality and accelerating cosmic expansion, while preserving virtually all of the major benefits of current scientific and mathematical paradigms.