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Blood Viscosity
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Book Synopsis Blood Viscosity by : Gregory D. Sloop
Download or read book Blood Viscosity written by Gregory D. Sloop and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The impact of blood viscosity on health and disease has been neglected, even though viscosity is a fundamental property of any fluid. It is inversely proportional to flow, so increased blood viscosity predisposes to thrombosis. Blood viscosity is directly related to systemic vascular resistance, and so blood viscosity affects blood pressure. Blood viscosity is inversely proportional to perfusion, and increased viscosity adversely affects the performance of all organs. By viewing them through the perspective of viscosity, this book provides fresh insight into atherosclerotic cardiovascular disease, hypertension, metabolic syndrome, sepsis, hemolytic anemias, anemia of chronic disease, and aging.
Book Synopsis Blood Viscosity by : Gregory D. Sloop
Download or read book Blood Viscosity written by Gregory D. Sloop and published by . This book was released on 2017 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: The impact of blood viscosity on health and disease has been neglected, even though viscosity is a fundamental property of any fluid. It is inversely proportional to flow, so increased blood viscosity predisposes to thrombosis. Blood viscosity is directly related to systemic vascular resistance, and so blood viscosity affects blood pressure. Blood viscosity is inversely proportional to perfusion, and increased viscosity adversely affects the performance of all organs. By viewing them through the perspective of viscosity, this book provides fresh insight into atherosclerotic cardiovascular disease, hypertension, metabolic syndrome, sepsis, hemolytic anemias, anemia of chronic disease, and aging.
Download or read book Blood Viscosity written by L. Dintenfass and published by Springer Science & Business Media. This book was released on 1985-03-31 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Clinical Aspects of Blood Viscosity and Cell Deformability by : G. D. O. Lowe
Download or read book Clinical Aspects of Blood Viscosity and Cell Deformability written by G. D. O. Lowe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: After many years of relative neglect, the importance of study of factors governing blood flow has at last achieved recognition; in this volume are documented many of the techniques, and the basic scientific and clinical observations, which have helped to open up understanding of this highly important aspect of human physiology and pathology in recent years. The text is logically divided into five sections beginning with blood cell deformability, then moving on to theoretical consideration of blood rheology, followed by accounts of the interrelationships between rheology, blood flow and vascular occlusion. The final two sections deal with blood rheology in clinical practice and therapeutic aspects of the study of blood flow. As regards blood cell deformability (Section A), the basic problem is set out by Kiesewetter and colleagues in the first paragraph of chapter 1 (p. 3), in which they point out that whereas human erythrocytes at rest have a diameter of approxi mately 7. 5 /-tm, nutritive capillaries have diameters ranging from 3-5 /-tm, and chapters in section A give an account of the ways in which the red cell can undergo deformation to permit capillary perfusion and the maintenance of the microcirculation.
Download or read book Clinical Hemorheology written by S. Chien and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: The task the editors have set themselves is to survey the field of clinical hemorheology from basic principles to up-to-date research. It is only in a new science like this that it is possible to span the whole field in a book of this size. Hemorheology, as a new approach to the study and management of a wide range of circulatory diseases, is now beginning to appear with increasing frequency in general as well as specialized medical journals. Hemorheology is also just beginning to creep into the undergraduate medical curriculum. Therefore, the majority of graduate doctors are unequipped to assess the place of hemorheology in the overall framework of circulatory physiology and pathology or to assess its relevance to their everyday practice. It is hoped that this book will fill this gap. The approach of the book is interdisciplinary. The first part deals with basic principles of blood flow, circulation and hemorheology. It has been written with the general doctor in mind, who has no special knowledge of hemodynamics and rheological concepts, terminology or methodology. To maintain the emphasis on practical clinical applications, all the chapters in the second part of the book have been written by clinical specialists practicing in the individual areas of disease. The book is so designed that clinicians may be able to read the relevant chapters in the second part of the book in isolation, using the basic science aspects contained in the first part of the book as reference chapters.
Book Synopsis Clinical Blood Rheology by : Gordon D.O. Lowe
Download or read book Clinical Blood Rheology written by Gordon D.O. Lowe and published by CRC Press. This book was released on 2019-06-04 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published in 1988: Study of blood flow properties (rheology) has attracted growing interest from clinicians in recent years. A United Kingdom meeting and a European meeting in 1979 resulted in previous publications summarizing the literature up to that time.
Book Synopsis Transfusion Medicine and Hemostasis by : Beth H. Shaz
Download or read book Transfusion Medicine and Hemostasis written by Beth H. Shaz and published by Newnes. This book was released on 2013-05-13 with total page 1015 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Transfusion Medicine and Hemostasis continues to be the only "pocket-size" quick reference for pathology residents and transfusion medicine fellows. It covers all topics in blood banking, transfusion medicine, and clinical and laboratory based coagulation. Short, focused chapters, organized by multiple hierarchical headings, are supplemented with up to 10 suggested reading citations. This single reference covers essentially all the topics required to meet the goals and objectives of a major program in transfusion medicine and clinical coagulation. New chapters in the coagulation testing section reflect the development of new tests available and their incorporation into clinical practice. Coverage includes essential updates on the importance of new cellular therapies, peripheral blood and bone marrow hematopoietic progenitor cells, as well as cord blood banking and regenerative medicine. The authors also examine advances in the understanding of molecular testing and pathogen reduction in two separate quality control chapters (one for blood centers and one for hospitals). Updated content covers new coagulation tests, cellular therapies, and quality control issues Easy to use, with focused, well-defined chapters in a standardized format throughout Offers quick "cross-reference" lists at the end of each chapter Includes lists of common abbreviations and indexes that cross reference diagnostic, clinical and therapeutic commonalities
Book Synopsis Regulation of Tissue Oxygenation, Second Edition by : Roland N. Pittman
Download or read book Regulation of Tissue Oxygenation, Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Book Synopsis Cardiovascular Physiology Concepts by : Richard E. Klabunde
Download or read book Cardiovascular Physiology Concepts written by Richard E. Klabunde and published by Lippincott Williams & Wilkins. This book was released on 2020-12-01 with total page 689 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praised for its concise coverage, this highly accessible monograph lays a foundation for understanding the underlying concepts of normal cardiovascular function and offers a welcome alternative to a more mechanistically oriented approach or an encyclopedic physiology text. Clear explanations, ample illustrations and engaging clinical cases and problems provide the perfect guidance for self-directed learning and prepare you to excel in clinical practice.
Book Synopsis Anatomy and Physiology by : J. Gordon Betts
Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Cerebral Circulation by : Marilyn J. Cipolla
Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
Book Synopsis Blood Viscosity and Shock by : H. Goslinga
Download or read book Blood Viscosity and Shock written by H. Goslinga and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hemodynamic significance of the flow properties of blood was put into perspective only during the past decade. Advances in modern technologies today allow the quantitative analy sis of the fluidity of blood and its components under conditions approximating the flow in vivo, particularly those in the microcirculation. The hematocrit is the most important of the determinants of blood fluidity (reciprocal value of blood viscosity); acute increases in the hematocrit exert deleterious effects on circulation and oxygen transport owing to impaired fluidity of blood. High viscosity of plasma due to hyper- or dysproteinemias initiates the microcirculatory dysfunctions in hyperviscosity syndromes. Furthermore, the fluidity or deformability of red cells might be critically diminished and therefore cause redistribution of blood elements and adversely affect the resistance to flow within the microvessels. In low flow states blood fluidity most likely becomes the key determinant for microvessel perfu sion, overriding the neural and local metabolic control mechanisms operative at physiological conditions to adjust blood supply to tissue demand. Microcirculatory disturbances are there fore encountered whenever driving pressures are reduced, as in shock or hypotension, and distal to stenoses of macrovessels, but also in hemoconcentration due to plasma volume con traction, polycythemia, leukemia, and dysproteinemia. Based on experimental studies exploring the possibilities and limitations, with regard to improving the fluidity of blood by reducing the hematocrit, the concept of intentional hemo dilution has been introduced to clinical medicine.
Book Synopsis What is the Clinical Implication of Whole Blood Viscosity in (Cardio)Vascular Medicine? by : Dr.Hakim Saboowala.
Download or read book What is the Clinical Implication of Whole Blood Viscosity in (Cardio)Vascular Medicine? written by Dr.Hakim Saboowala. and published by Dr.Hakim Saboowala. This book was released on 2019-10-09 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whole blood is a non-Newtonian fluid (A non-Newtonian fluid is a fluid that does not follow Newton's law of viscosity, i.e. constant viscosity independent of stress.), which means that its viscosity depends on shear rate. [Shear Rate: Shear rate is the rate of change of velocity at which one layer of fluid passes over an adjacent layer e.g. consider that a fluid is placed between two parallel plates that are 1.0 cm apart, the upper plate moving at a velocity of 1.0 cm/sec and the lower plate fixed.] At low shear, blood cells aggregate, which induces a sharp increase in viscosity, whereas at higher shear blood cells disaggregate, deform and align in the direction of flow. Other important determinants of blood viscosity are: · The Haematocrit, · The presence of Macromolecules in the medium, · Temperature and, · The deformability of Red blood cells (at high shear). At the sites of severe atherosclerotic obstructions or at vasospastic locations, when change of vessel diameter is limited, blood viscosity contributes to stenotic resistance thereby jeopardizing tissue perfusion. However, blood viscosity plays its most important role in the microcirculation where it contributes significantly to peripheral resistance and may cause sludging in the postcapillary venules. Apart from the direct haemodynamic significance, an increase in blood viscosity at low shear by red blood cell aggregation is also associated with increased thrombotic risk, as has been demonstrated in atrial fibrillation. Furthermore, as increased red blood cell aggregation is a reflection of inflammation, hyperviscosity has been shown to be a marker of inflammatory activity. Thus, because of its potential role in haemodynamics, thrombosis and inflammation, it has been attempted in this Booklet to emphasize the determination of the whole blood viscosity as it could provide useful information for diagnostics and therapy of(cardio)vascular disease. ……Dr.H.K.Saboowala.
Book Synopsis High Resolution Imaging in Microscopy and Ophthalmology by : Josef F. Bille
Download or read book High Resolution Imaging in Microscopy and Ophthalmology written by Josef F. Bille and published by Springer. This book was released on 2019-08-13 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.
Book Synopsis The Impact of Food Bioactives on Health by : Kitty Verhoeckx
Download or read book The Impact of Food Bioactives on Health written by Kitty Verhoeckx and published by Springer. This book was released on 2015-04-29 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Infogest” (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture that will last for 4 years from April 4, 2011. Infogest aims at building an open international network of institutes undertaking multidisciplinary basic research on food digestion gathering scientists from different origins (food scientists, gut physiologists, nutritionists...). The network gathers 70 partners from academia, corresponding to a total of 29 countries. The three main scientific goals are: Identify the beneficial food components released in the gut during digestion; Support the effect of beneficial food components on human health; Promote harmonization of currently used digestion models Infogest meetings highlighted the need for a publication that would provide researchers with an insight into the advantages and disadvantages associated with the use of respective in vitro and ex vivo assays to evaluate the effects of foods and food bioactives on health. Such assays are particularly important in situations where a large number of foods/bioactives need to be screened rapidly and in a cost effective manner in order to ultimately identify lead foods/bioactives that can be the subject of in vivo assays. The book is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest and highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated and, as noted above, highlight the strengths and weaknesses of the various assays. It is also an important resource for undergraduate students in the ‘food and health’ arena.
Book Synopsis Blood Microrheology: Viscosity Factors in Blood Flow, Ischaemia, and Thrombosis by : Leopold Dintenfass
Download or read book Blood Microrheology: Viscosity Factors in Blood Flow, Ischaemia, and Thrombosis written by Leopold Dintenfass and published by Butterworths. This book was released on 1971 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Red Blood Cell Aggregation by : Oguz Baskurt
Download or read book Red Blood Cell Aggregation written by Oguz Baskurt and published by CRC Press. This book was released on 2011-09-28 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Red blood cells in humans—and most other mammals—have a tendency to form aggregates with a characteristic face-to-face morphology, similar to a stack of coins. Known as rouleaux, these aggregates are a normally occurring phenomenon and have a major impact on blood rheology. What is the underlying mechanism that produces this pattern? Does this really happen in blood circulation? And do these rouleaux formations have a useful function? The first book to offer a comprehensive review of the subject, Red Blood Cell Aggregation tackles these and other questions related to red blood cell (RBC) aggregates. The book covers basic, clinical, and physiological aspects of this important biophysical phenomenon and integrates these areas with concepts in bioengineering. It brings together state-of-the-art research on the determinants, mechanisms, and measurement and effects of RBC aggregation as well as on variations and comparative aspects. After an introductory overview, the book outlines factors and conditions that affect RBC aggregation. It presents the two hypotheses—the bridging model and the depletion model—that provide potential mechanisms for the adhesive forces that lead to the regular packing of the cells in rouleaux formations. The book also reviews the methods used to quantify RBC aggregation in vitro, focusing on their importance in clinical practice. Chapters discuss the effect of RBC aggregation on the in vitro rheology of blood as well as on tube flow. The book also looks at what happens in the circulation when red blood cells aggregate and examines variations due to physiological and pathophysiological challenges. The concluding chapter explores the formation of red blood cell aggregates in other mammals. Written by leading researchers in the field, this is an invaluable resource for basic science, medical, and clinical researchers; graduate students; and clinicians interested in mammalian red blood cells.
