Biomedical Product Development Bench To Bedside

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Biomedical Product Development: Bench to Bedside

Author : Babak Arjmand
Publisher : Springer Nature
ISBN 13 : 3030356264
Total Pages : 164 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Biomedical Product Development: Bench to Bedside by : Babak Arjmand

Download or read book Biomedical Product Development: Bench to Bedside written by Babak Arjmand and published by Springer Nature. This book was released on 2020-02-05 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers all the steps in manufacturing a biomedical product from bench to bedside. It specifically focuses on quality assurance and management and explains the different good practice principles in the various phases of product development as well as how to fulfill them: Good laboratory practice, good manufacturing practice and good clinical practice. It provides readers with the know-how to design biomedical experiments to ensure quality and integrity, to plan and conduct standard preclinical studies and to assure the quality of the final manufactured biomedical products. Importantly, it also addresses ethical concerns and considerations. The book discusses the guidelines and ethical considerations for preclinical and clinical studies, to allow readers to identify safety concerns regarding biomedical products and to improve pre-clinical studies for the development of better products. This textbook is a valuable guide for biomedical students (B.Sc., M.S., and Ph.D. students) in the field of molecular medicine, medical biotechnology, stem cell research and related areas, as well as for professionals such as quality control staff, tissue bankers, policy-makers and health professionals.

Cell Biology and Translational Medicine, Volume 16

Author : Kursad Turksen
Publisher : Springer Nature
ISBN 13 : 3031106385
Total Pages : 197 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis Cell Biology and Translational Medicine, Volume 16 by : Kursad Turksen

Download or read book Cell Biology and Translational Medicine, Volume 16 written by Kursad Turksen and published by Springer Nature. This book was released on 2022-07-28 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 16th volume of a continuing series. Chapter "Epithelial Stem Cells: Making, Shaping and Breaking the Niche" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Ophthalmic Product Development

Author : Seshadri Neervannan
Publisher : Springer
ISBN 13 : 9783030763695
Total Pages : 0 pages
Book Rating : 4.7/5 (636 download)

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Book Synopsis Ophthalmic Product Development by : Seshadri Neervannan

Download or read book Ophthalmic Product Development written by Seshadri Neervannan and published by Springer. This book was released on 2023-02-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive textbook addressing the unique aspects of drug development for ophthalmic use. Beginning with a perspective on anatomy and physiology of the eye, the book provides a critical appraisal of principles that underlie ocular drug product development. The coverage encompasses topical and intraocular formulations, small molecules and biologics (including protein and gene therapies), conventional formulations (including solutions, suspensions, and emulsions), novel formulations (including nanoparticles, microparticles, and hydrogels), devices, and specialty products. Critical elements such as pharmacokinetics, influence of formulation technologies and ingredients, as well as impact of disease conditions on products development are addressed. Products intended for both the front and the back of the eye are discussed with an eye towards future advances.

Cell Biology and Translational Medicine, Volume 17

Author : Kursad Turksen
Publisher : Springer Nature
ISBN 13 : 3031205146
Total Pages : 249 pages
Book Rating : 4.0/5 (312 download)

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Book Synopsis Cell Biology and Translational Medicine, Volume 17 by : Kursad Turksen

Download or read book Cell Biology and Translational Medicine, Volume 17 written by Kursad Turksen and published by Springer Nature. This book was released on 2022-11-01 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 17th volume of a continuing series.

Biofertilizers

Author : Inamuddin
Publisher : John Wiley & Sons
ISBN 13 : 1119724678
Total Pages : 690 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Biofertilizers by : Inamuddin

Download or read book Biofertilizers written by Inamuddin and published by John Wiley & Sons. This book was released on 2021-08-03 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: Great attention has been paid to reduce the use of conventional chemical fertilizers harming living beings through food chain supplements from the soil environment. Therefore, it is necessary to develop alternative sustainable fertilizers to enhance soil sustainability and agriculture productivity. Biofertilizers are the substance that contains microorganisms (bacteria, algae, and fungi) living or latent cells that can enrich the soil quality with nitrogen, phosphorous, potassium, organic matter, etc. They are a cost-effective, biodegradable, and renewable source of plant nutrients/supplements to improve the soil-health properties. Biofertilizers emerge as an attractive alternative to chemical fertilizers, and as a promising cost-effective technology for eco-friendly agriculture and a sustainable environment that holds microorganisms which enhance the soil nutrients' solubility leading a raise in its fertility, stimulates crop growth and healthy food safety. This book provides in-depth knowledge about history and fundamentals to advances biofertilizers, including latest reviews, challenges, and future perspectives. It covers fabrication approaches, and various types of biofertilizers and their applications in agriculture, environment, forestry and industrial sectors. Also, organic farming, quality control, quality assurance, food safety and case-studies of biofertilizers are briefly discussed. Biofertilizers' physical properties, affecting factors, impact, and industry profiles in the market are well addressed. This book is an essential guide for farmers, agrochemists, environmental engineers, scientists, students, and faculty who would like to understand the science behind the sustainable fertilizers, soil chemistry and agroecology.

Biomedical Applications of Electrospinning and Electrospraying

Author : Naresh Kasoju
Publisher : Woodhead Publishing
ISBN 13 : 0128224908
Total Pages : 484 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Biomedical Applications of Electrospinning and Electrospraying by : Naresh Kasoju

Download or read book Biomedical Applications of Electrospinning and Electrospraying written by Naresh Kasoju and published by Woodhead Publishing. This book was released on 2021-05-05 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomedical Applications of Electrospinning and Electrospraying describes the principles and laboratory set up for electrospinning and electrospraying, addressing a range of biomedical applications. Sections cover novel combinational approaches, such as electrospinning/spraying and 3D printing. Electrospinning has evolved from being a technique to prepare random networks of textile fibers to a technique to fabricate highly ordered patterns of biomedical materials of defined scale. The technological advancements in recent years with regard to the way the jet is facilitated, how the jet path is controlled, and how the fibers are collected have provided invaluable insights into controlled fabrication of a material of choice. Additionally, the electrospray technique has also evolved from being a technique to prepare food formulations to a technique to prepare cell encapsulated beads for transplantation in clinics. Several innovations in this line, such as those leading to core-shell materials have tremendously changed the way the technique is used. Thus, a combinational approach using electrospinning, electrospraying and 3D printing has emerged. Introduces electrospinning and electrospraying concepts and describes state-of-the-art methodologies Provides comprehensive coverage of electrospun/spray materials in drug delivery, tissue engineering and biosensor applications Presents details of instrumentation involved, along with novel devices for bench to bedside translation, Covers novel combinational approaches using electrospinning, electrospraying and 3D printingIntroduces electrospinning and electrospraying concepts and describes state-of-the-art methodologies Provides comprehensive coverage of electrospun/spray materials in drug delivery, tissue engineering and biosensor applications Presents details of instrumentation involved, along with novel devices for bench to bedside translation Covers novel combinational approaches using electrospinning, electrospraying and 3D printing

Bioactive Components

Author : Monika Thakur
Publisher : Springer Nature
ISBN 13 : 9811923663
Total Pages : 609 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Bioactive Components by : Monika Thakur

Download or read book Bioactive Components written by Monika Thakur and published by Springer Nature. This book was released on 2022-12-01 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book compiles updated information about the role and health benefits of various bioactives in food. Different chapters are contributed by academicians, food scientists, technologists, and medical practitioners. The book addresses both theoretical and applied aspects of bioactive components and provides exhaustive knowledge about bioactive components. It comprises 27 chapters organized into 4 major sections covering topics in food science and technology, functional foods, and nutraceuticals. It provides perspectives for innovation, sources, applications, and sustainability in bioactive component research. The first section starts with introduction of bioactive components consisting of seven different chapters primarily focusing on the bioactive components and their sources with respective health benefits. The second section, comprising five different chapters, deals with different technological trends, regulations, and safety aspects of bioactive components. With eight chapters, the third section covers the role of bioactive components in human health and the role of functional foods in combating various health-related issues. The fourth section reviews functional foods through six chapters that cover the use of bioactive components in various food products. The book will prove useful to advanced food technology graduate and undergraduate students and research scholars, practicing food technologists in food and related industries, entrepreneurs, food-pharma researchers, and other scientists seeking information about smart and sustainable processes as well as information needed to design and develop these processes.

Development of FDA-Regulated Medical Products

Author : Elaine Whitmore
Publisher : Quality Press
ISBN 13 : 0873892216
Total Pages : 257 pages
Book Rating : 4.8/5 (738 download)

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Book Synopsis Development of FDA-Regulated Medical Products by : Elaine Whitmore

Download or read book Development of FDA-Regulated Medical Products written by Elaine Whitmore and published by Quality Press. This book was released on 2012-02-15 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translating promising discoveries and innovations into useful, marketable medical products demands a robust process to guide nascent products through a tangle of scientific, clinical, regulatory, economic, social, and legal challenges. There are so many human and environmental elements involved in shepherding medical advances from lab to launch that the field of medical product development has been referred to as an ecosystem. The purpose of this book is to help provide a shared foundation from which cross-functional participants in that ecosystem can negotiate the product development labyrinth and accomplish the goal of providing both groundbreaking and iterative new medical products. The book is intended for anyone in industry, the public sector, or academia—regardless of functional specialty, workplace, or seniority—who is interested in medical product development. The years since the publication of the previous edition of this book have seen profound changes in the actions and attitudes of patients, insurers, manufacturers, and the Food and Drug Administration regarding the streamlining of medical product development and approval. What those years have not seen is a concomitant increase in innovative treatments with profound benefits to patients. Despite enormous investments in research by both private and public sources and a surge in scientific and technological advances, new medical products barely trickle into the marketplace. For a variety of reasons, applied sciences necessary for medical product development are not keeping pace with the tremendous advances in basic sciences. Not surprisingly, industry and academia are under substantial pressure to transform discoveries and innovations from the laboratory into safe and effective medical products to benefit patients and improve health. This evolution—from bench to bedside—has become known as translational research and development, and this approach is what this book illuminates. "I have been working in medical device design and design assurance for over 10 years...Elaine Whitmore really gets this right...The point is that quality regulations are not going to go away, and those responsible for healthcare product development will have to lead the charge to keep up the momentum in their organizations. I am going to have to buy several copies of this for my clients!" Joseph P. Sener, P.E.

Using Animal Models in Biomedical Research

Author : Pierce K. H. Chow
Publisher : World Scientific
ISBN 13 : 9812706631
Total Pages : 309 pages
Book Rating : 4.8/5 (127 download)

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Book Synopsis Using Animal Models in Biomedical Research by : Pierce K. H. Chow

Download or read book Using Animal Models in Biomedical Research written by Pierce K. H. Chow and published by World Scientific. This book was released on 2008 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal models play crucial roles in the continuum of experimental activities that make up biomedical research. This book fills this gap in knowledge and provides material not easily sourced by the average biomedical researcher, such as current information biosafety, animal protocal design and histological-pathological support.

Design of Biomedical Devices and Systems, 4th edition

Author : Paul H. King
Publisher : CRC Press
ISBN 13 : 0429786050
Total Pages : 725 pages
Book Rating : 4.4/5 (297 download)

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Book Synopsis Design of Biomedical Devices and Systems, 4th edition by : Paul H. King

Download or read book Design of Biomedical Devices and Systems, 4th edition written by Paul H. King and published by CRC Press. This book was released on 2018-10-03 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fourth edition is a substantial revision of a highly regarded text, intended for senior design capstone courses within departments of biomedical engineering, bioengineering, biological engineering and medical engineering, worldwide. Each chapter has been thoroughly updated and revised to reflect the latest developments. New material has been added on entrepreneurship, bioengineering design, clinical trials and CRISPR. Based upon feedback from prior users and reviews, additional and new examples and applications, such as 3D printing have been added to the text. Additional clinical applications were added to enhance the overall relevance of the material presented. Relevant FDA regulations and how they impact the designer’s work have been updated. Features Provides updated material as needed to each chapter Incorporates new examples and applications within each chapter Discusses new material related to entrepreneurship, clinical trials and CRISPR Relates critical new information pertaining to FDA regulations. Presents new material on "discovery" of projects "worth pursuing" and design for health care for low-resource environments Presents multiple case examples of entrepreneurship in this field Addresses multiple safety and ethical concerns for the design of medical devices and processes

Empathy

Author : Jean Decety
Publisher : MIT Press
ISBN 13 : 026252595X
Total Pages : 335 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Empathy by : Jean Decety

Download or read book Empathy written by Jean Decety and published by MIT Press. This book was released on 2014-01-10 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent work on empathy theory, research, and applications, by scholars from disciplines ranging from neuroscience to psychoanalysis. There are many reasons for scholars to investigate empathy. Empathy plays a crucial role in human social interaction at all stages of life; it is thought to help motivate positive social behavior, inhibit aggression, and provide the affective and motivational bases for moral development; it is a necessary component of psychotherapy and patient-physician interactions. This volume covers a wide range of topics in empathy theory, research, and applications, helping to integrate perspectives as varied as anthropology and neuroscience. The contributors discuss the evolution of empathy within the mammalian brain and the development of empathy in infants and children; the relationships among empathy, social behavior, compassion, and altruism; the neural underpinnings of empathy; cognitive versus emotional empathy in clinical practice; and the cost of empathy. Taken together, the contributions significantly broaden the interdisciplinary scope of empathy studies, reporting on current knowledge of the evolutionary, social, developmental, cognitive, and neurobiological aspects of empathy and linking this capacity to human communication, including in clinical practice and medical education.

Stem Cells and Lineage Commitment

Author : Kursad Turksen
Publisher : Springer Nature
ISBN 13 : 1071635379
Total Pages : 228 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Stem Cells and Lineage Commitment by : Kursad Turksen

Download or read book Stem Cells and Lineage Commitment written by Kursad Turksen and published by Springer Nature. This book was released on 2023-12-09 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume explores a variety of techniques used to study lineage commitment in stem cells. Further elucidation of the process that stem cells undergo on their way to becoming more specified cell types is vital for a more complete understanding of cell biology and overall physiology. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Stem Cells and Lineage Commitment: Methods and Protocols serves as an ideal guide for experts and novices in the field of stem cell biology.

Real-World Evidence in Medical Product Development

Author : Weili He
Publisher : Springer Nature
ISBN 13 : 3031263286
Total Pages : 431 pages
Book Rating : 4.0/5 (312 download)

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Book Synopsis Real-World Evidence in Medical Product Development by : Weili He

Download or read book Real-World Evidence in Medical Product Development written by Weili He and published by Springer Nature. This book was released on 2023-05-11 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides state-of-art statistical methodologies, practical considerations from regulators and sponsors, logistics, and real use cases for practitioners for the uptake of RWE/D. Randomized clinical trials have been the gold standard for the evaluation of efficacy and safety of medical products. However, the cost, duration, practicality, and limited generalizability have incentivized many to look for alternative ways to optimize drug development. This book provides a comprehensive list of topics together to include all aspects with the uptake of RWE/D, including, but not limited to, applications in regulatory and non-regulatory settings, causal inference methodologies, organization and infrastructure considerations, logistic challenges, and practical use cases.

Principles of Translational Science in Medicine

Author : Martin Wehling
Publisher : Academic Press
ISBN 13 : 0128007214
Total Pages : 364 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Principles of Translational Science in Medicine by : Martin Wehling

Download or read book Principles of Translational Science in Medicine written by Martin Wehling and published by Academic Press. This book was released on 2015-04-02 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine. Provides an in-depth description of novel tools for the assessment of translatability of trials to balance risk and improve projects at any given stage of product development New chapters deal with translational issues in the fastest growing population (the elderly), case studies, translatability assessment tools, and advances in nanotherapies Details IPR issues of translation, especially for public-private-partnerships Contains contributions from world leaders in translational medicine, including the former NIH director and authorities from various European regulatory institutions

Contemporary Accounts in Drug Discovery and Development

Author : Xianhai Huang
Publisher : John Wiley & Sons
ISBN 13 : 1119627818
Total Pages : 484 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Contemporary Accounts in Drug Discovery and Development by : Xianhai Huang

Download or read book Contemporary Accounts in Drug Discovery and Development written by Xianhai Huang and published by John Wiley & Sons. This book was released on 2022-03-11 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: CONTEMPORARY ACCOUNTS IN DRUG DISCOVERY AND DEVELOPMENT A useful guide for medicinal chemists and pharmaceutical scientists Drug discovery is a lengthy and complex process that typically involves identifying an unmet medical need, determining a biological target, chemical library screening to identify a lead, chemical optimization, preclinical studies and clinical trials. This process often takes many years to complete, and relies on practitioners’ knowledge of chemistry and biology, but also—and perhaps more importantly—on experience. Improving the success rate in discovery and development through a thorough knowledge of drug discovery principles and advances in technology is critical for advancement in the field. Contemporary Accounts in Drug Discovery and Development provides drug discovery scientists with the knowledge they need to quickly gain mastery of the drug discovery process. A thorough accounting is given for each drug covered within the book, as the authors provide pharmacology, drug metabolism, biology, drug development, and clinical studies for every case, with modern drug discovery principles and technologies incorporated throughout. Contemporary Accounts in Drug Discovery and Development readers will also find Case histories used as an engaging way of learning about the drug discovery/development process Detailed biological rational and background information, drug design principles, SAR development, ADMET considerations, and clinical studies The full history of individual marketed small molecule drugs Coverage of drug candidates that have passed Phase I clinical trials with different modalities, such as antibody drug conjugates (ADC), proteolysis-targeting chimera (PROTAC), and peptide drugs The application of new technologies in drug discovery such as DNA-encoded libraries (DEL), positron emission tomography (PET), and physics-based computational modeling employing free energy perturbation (FEP) Contemporary Accounts in Drug Discovery and Development is a helpful tool for medicinal chemists, organic chemists, pharmacologists, and other scientists in drug research and process development. It may be considered essential reading for graduate courses in drug discovery, medicinal chemistry, drug synthesis, pharmaceutical science, and pharmacology. It is also a useful resource for pharmaceutical industry labs, as well as for libraries.

Cancer Biomarkers in Body Fluids

Author : Gabriel D. Dakubo
Publisher : Springer
ISBN 13 : 331901580X
Total Pages : 299 pages
Book Rating : 4.3/5 (19 download)

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Book Synopsis Cancer Biomarkers in Body Fluids by : Gabriel D. Dakubo

Download or read book Cancer Biomarkers in Body Fluids written by Gabriel D. Dakubo and published by Springer. This book was released on 2016-09-01 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: The molecular and genetic signatures of cancer are represented in the peripheral circulation and other body fluids, giving rise to the “liquid biopsy” concept. This new paradigm of molecular profiling of cancer cells offers several advantages over traditional tissue biopsy. It is convenient, noninvasive, conforms to current clinical practice, enables real time disease monitoring and the study of tumor evolution, can easily be sampled multiple times, and this sample is more representative of the heterogeneous cancer cells than biopsy sampling. Indeed, all aspects of cancer molecular genetic information, stemming from DNA (both nuclear and mitochondria), RNA (coding and noncoding), peptides and proteins, metabolites and lipids are present in body fluids as free, cell surface bound or enclosed in membrane vesicles, and are being harnessed for disease management. Additionally, circulating tumor, and tumor stem cells provide prognostic information, and also enable the study of the intricate molecular processes associated with metastasis and drug resistance. This treatise deals with the general principles of the molecular pathology of cancer, and its associated imprints in circulation. The transitional process from discovery, prototype development, translational research, to product development can be complex and costly. The critical path to biomarker development and qualification for successful use in drug development is detailed herein as well. This book is of interest to Cancer Researchers, Oncologists, Clinicians, Surgeons, Medical Students, Nurses, Diagnostic Laboratories, and Pharmaceutical Industries.

Planning for a Career in Biomedical and Life Sciences

Author : Avrum I. Gotlieb
Publisher : Academic Press
ISBN 13 : 0128149795
Total Pages : 184 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Planning for a Career in Biomedical and Life Sciences by : Avrum I. Gotlieb

Download or read book Planning for a Career in Biomedical and Life Sciences written by Avrum I. Gotlieb and published by Academic Press. This book was released on 2018-05-31 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Planning for a Career in Biomedical and Life Sciences:Learn to Navigate a Tough Research Culture by Harnessing the Power of Career Building, Second Edition, presents useful information, insights and tips to those pursuing a career in the biomedical and life sciences. The book focuses on making educated choices during schooling, training, and the job search in both the academic and non-academic sectors. The book's premise lies in the notion that if users understand the full path of a career in either the biomedical or life science fields, they can proactively plan their career, recognize any opportunities that present themselves, and be well prepared to address important aspects of their own professional development. Topics include choosing a training path, selecting the best supervisor/mentor, and negotiating a job offer. Updates to this edition include an outline of core competencies to achieve success, how to build soft skills and tailor them to specific job opportunities, and how to increase collaborations across disciplines. Additionally, coverage on issues around diversity, health, wellness and work/life balance are expanded. This book is a valuable resource for undergraduate, graduate, medical and postdoctoral students in the biomedical and life sciences, as well as academic faculty and advisors. Revised and updated to address dealing with student failure and rejection and developing resilience Provides strategies on evaluating biomedical and life sciences education and professional development opportunities in a thorough and systematic fashion Discusses possible pitfalls and offers insight into how to navigate successfully at various points of a scientist’s career Offers valuable advice on how to make the best choices for yourself at any stage in your career and how to choose supervisors and mentors who will support your career goals