Biomarkers Of Radiation In The Environment

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Biomarkers of Radiation in the Environment

Author : Michael D. Wood
Publisher : Springer Nature
ISBN 13 : 9402421017
Total Pages : 333 pages
Book Rating : 4.4/5 (24 download)

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Book Synopsis Biomarkers of Radiation in the Environment by : Michael D. Wood

Download or read book Biomarkers of Radiation in the Environment written by Michael D. Wood and published by Springer Nature. This book was released on 2022-04-04 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: This proceedings volume results from the NATO Advanced Research Workshop on 'Biomarkers of Radiation in the Environment: Robust Tools for Risk Assessment (BRITE)’. The BRITE workshop discussed insights from cancer research, epigenetics, non-human and human risk assessment, since many of the state-of-the-art biomarkers being developed for humans deserve consideration for environmental applications and vice versa. Sessions were very wide-ranging covering methods, mechanisms, cross disciplinary application and regulation. The chapters in this book have been grouped into five major themes that were covered by the BRITE workshop: · Techniques for biomarker development · Low-dose effect mechanisms · Biomarkers for risk evaluation · Biomarkers in wildlife · Biomarker use and responses Each chapter has been written independently and reflects the views of the chapter author(s). Therefore, the readers can form their own balanced view of the different perspectives on biomarkers of radiation in the environment. Given the breadth of topics covered and the state-of-the-art perspectives shared by leading experts in their respective fields, this book should form a valuable resource for anyone with an interest in how biomarkers can be used to improve our understanding of radiation in the environment and its potential impacts.

Biological Dosimetry

Author : W. G. Eisert
Publisher : Springer Science & Business Media
ISBN 13 : 3642693342
Total Pages : 343 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Biological Dosimetry by : W. G. Eisert

Download or read book Biological Dosimetry written by W. G. Eisert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: In October 1982, a small international symposium was held at the Gesellschaft fUr Strahlen- und Umweltforschung mbH (GSF) in Munich as a satellite meeting of the IX International Conference on Analytical Cytology. The symposium focussed on cytometric approaches to biological dosimetry, and was, to the best of our knowledge, the first meeting on this subject ever held. There was strong encouragement from the 75 attendees and from others to publish a proceedings of the symposium. Hence this book, containing 30 of the 36 presentations, has been assembled. Dosimetry, the accurate and systematic determination of doses, usually refers to grams of substance administered or rads of ionization or some such measure of exposure of a patient, a victim or an experimental system. The term also can be used to describe the quantity of an ultimate, active agent as delivered to the appropriate target material within a biological system. Thus, for mutagens, one can speak of DNA dosimetry, meaning the number of adducts produced in the DNA of target cells such as bone-mar row stem cells or spermatogonia.

Biomarkers and Occupational Health

Author : Mary Janet Normandy
Publisher : Joseph Henry Press
ISBN 13 : 9780309176408
Total Pages : 375 pages
Book Rating : 4.1/5 (764 download)

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Book Synopsis Biomarkers and Occupational Health by : Mary Janet Normandy

Download or read book Biomarkers and Occupational Health written by Mary Janet Normandy and published by Joseph Henry Press. This book was released on 1995-01-16 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers have emerged as an exciting tool in disease prevention, particularly in the workplace. They may be used to document workers' exposure to toxins, signal the onset of health effects, or identify individuals with susceptibility to certain environmental threats. But the uncertainty is as great as the potential. Are biomarkers suitable for widespread use? How can they be deployed in diverse contexts? How can biological information about workers be handled fairly and ethically? Biomarkers and Occupational Health describes the state of biomarker development, including the implications of the Human Genome program, and presents a range of viewpoints on the future of biomarkers from the leaders in the field. This book explores the three basic types of biomarkers (markers of exposure, markers of health effects, and markers of susceptibility to disease) from a variety of perspectives. It examines what can be learned from well-known exposure sitesâ€"Hiroshima and Nagasaki, Chernobyl, and the Hanford nuclear site in the United States, for exampleâ€"and a wide range of human cases and animal studies. The book also explores the costs and ramifications of developing a large-scale program to monitor potentially exposed workers (e.g., at a cleanup site). A framework is offered for the use of biomarkers based on the mandate to "change the environment before you change the worker." The book explores how to identify ethical issues, how to set development priorities, and how to integrate biomarkers into an occupational health and safety program. The authors present the latest technical findings about markers for chronic beryllium disease as well as markers for exposure to carcinogens, radiation, and chroniumâ€"including prospects for detecting long-past exposures. Biomarkers and Occupational Health offers an update on biomarker development and explores a wide scope of issues. This book will be important to occupational health professionals, biomedical researchers, toxicologists, epidemiologists, and labor and management officials involved in worker health issues. Moritmer L. Mendelsohn, M.D., Ph.D., is Vice-Chairman of the Radiation Effects Research Foundation (RERF) in Japan, which studies the long-term health effects of the atomic blasts in Hiroshima and Nagasaki, and he is former Associate Director of the Lawrence Livermore National Laboratory in California. John P. Peeters, Ph.D., is a geneticist who is currently directing a division of the Office of Occupational Medicine for the United States Department of Energy. Mary Janet Normandy, Ph.D., is a toxicologist who specializes in the metabolism of xenobiotics in mammalian systems. She is currently a member of the Department of Energy's Office of Occupational Medicine.

Biomarkers: A Pragmatic Basis for Remediation of Severe Pollution in Eastern Europe

Author : David B. Peakall
Publisher : Springer Science & Business Media
ISBN 13 : 9401145504
Total Pages : 324 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Biomarkers: A Pragmatic Basis for Remediation of Severe Pollution in Eastern Europe by : David B. Peakall

Download or read book Biomarkers: A Pragmatic Basis for Remediation of Severe Pollution in Eastern Europe written by David B. Peakall and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many areas of Eastern Europe have been polluted to an extent unknown in the West. Four such sites - Kola Peninsula, northern Bohemia, upper Vistula Basin, and Katowice - have been identified and detailed accounts of the pollution at these sites are given. The current status of the use of biomarkers in hazard assessment is given by several scientists from NATO countries. Four working groups, comprising scientists working on the polluted sites and western scientists with expertise in biomarkers, examine the use of biomarkers to assess the environmental health of each of these areas and make recommendations on the future direction of remedial action in these areas.

Biomarkers of Environmental Contamination

Author : John F. McCarthy
Publisher :
ISBN 13 : 9781351095617
Total Pages : 457 pages
Book Rating : 4.0/5 (956 download)

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Book Synopsis Biomarkers of Environmental Contamination by : John F. McCarthy

Download or read book Biomarkers of Environmental Contamination written by John F. McCarthy and published by . This book was released on 2018 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: "How can biological markers help assess and predict human health risks? Find out the answers to this question and others in this timely new book examining the use of biological markers in animals and plants for evaluating the ecological and health effects of environmental contamination. The book explains the concept of environmental sentinels, presents example of field studies and discusses the utility of biomarkers within a risk analysis paradigm. Anyone who needs to know how to assess and predict environmental contamination should consider this book essential reading."--Provided by publisher.

WHO Handbook on Indoor Radon

Author : World Health Organization
Publisher : World Health Organization
ISBN 13 : 9241547677
Total Pages : 111 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis WHO Handbook on Indoor Radon by : World Health Organization

Download or read book WHO Handbook on Indoor Radon written by World Health Organization and published by World Health Organization. This book was released on 2009 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook focuses on residential radon exposure from a public health point of view and provides detailed recommendations on reducing health risks from radon and sound policy options for preventing and mitigating radon exposure. The material in the handbook reflects the epidemiological evidence that indoor radon exposure is responsible for a substantial number of lung cancers in the general population. Information is provided on the selection of devices to measure radon levels and on procedures for the reliable measurement of these levels. Discussed also are control options for radon in new dwellings, radon reduction in existing dwellings as well as assessment of the costs and benefits of different radon prevention and remedial actions. Also covered are radon risk communication strategies and organization of national radon programs.--Publisher's description.

Environmental Pollutant Exposures and Public Health

Author : R M Harrison
Publisher : Royal Society of Chemistry
ISBN 13 : 1839160446
Total Pages : 243 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Environmental Pollutant Exposures and Public Health by : R M Harrison

Download or read book Environmental Pollutant Exposures and Public Health written by R M Harrison and published by Royal Society of Chemistry. This book was released on 2020-10-27 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Both genes and environment have profound effects upon our health. While some environmental factors such as polluted air are high in the public consciousness, there are many other pathways for people’s exposure to toxic chemicals, such as through food, water and contaminated land. It is not only chemicals that can affect health; environmental radioactivity, pathogenic organisms and our changing climate also have implications for public health, and all contribute to the global burden of disease, leading to both disability and deaths of millions of people annually across the world. An understanding of the pathways of environmental exposure, and its effects upon health is key to developing regulations and behaviours that reduce or prevent exposure, and the consequent impacts upon health. Covering topics from dietary exposure to chemicals through to the health effects of climate change, this book brings together contributors from around the world to highlight the latest science on the impacts of environmental pollutant exposure upon public health.

Animal Biomarkers as Pollution Indicators

Author : David B. Peakall
Publisher : Springer Science & Business Media
ISBN 13 : 9401123462
Total Pages : 312 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Animal Biomarkers as Pollution Indicators by : David B. Peakall

Download or read book Animal Biomarkers as Pollution Indicators written by David B. Peakall and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ecotoxicology is a relatively new scientific discipline. Indeed, it might be argued that it is only during the last 5-10 years that it has come to merit being regarded as a true science, rather than a collection of procedures for protecting the environment through management and monitoring of pollutant discharges into the environment. The term 'ecotoxicology' was first coined in the late sixties by Prof. Truhaut, a toxicologist who had the vision to recognize the importance of investigating the fate and effects of chemicals in ecosystems. At that time, ecotoxicology was considered a sub-discipline of medical toxicology. Subsequently, several attempts have been made to portray ecotoxicology in a more realistic light. Notably, both F. Moriarty (1988) and F. Ramade (1987) emphasized in their books the broad basis of ecotoxicology, encompassing chemical and radiation effects on all components of ecosystems. In doing so, they and others have shifted concern from direct chemical toxicity to man, to the far more subtle effects that pollutant chemicals exert on natural biota. Such effects potentially threaten the existence of all life on Earth. Although I have identified the sixties as the era when ecotoxicology was first conceived as a coherent subject area, it is important to acknowledge that studies that would now be regarded as ecotoxicological are much older. Wherever people's ingenuity has led them to change the face of nature significantly, it has not escaped them that a number of biological con sequences, often unfavourable, ensue.

Chemical Biomarkers in Aquatic Ecosystems

Author : Thomas S. Bianchi
Publisher : Princeton University Press
ISBN 13 : 1400839106
Total Pages : 417 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis Chemical Biomarkers in Aquatic Ecosystems by : Thomas S. Bianchi

Download or read book Chemical Biomarkers in Aquatic Ecosystems written by Thomas S. Bianchi and published by Princeton University Press. This book was released on 2011-02-28 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a unique and thorough look at the application of chemical biomarkers to aquatic ecosystems. Defining a chemical biomarker as a compound that can be linked to particular sources of organic matter identified in the sediment record, the book indicates that the application of these biomarkers for an understanding of aquatic ecosystems consists of a biogeochemical approach that has been quite successful but underused. This book offers a wide-ranging guide to the broad diversity of these chemical biomarkers, is the first to be structured around the compounds themselves, and examines them in a connected and comprehensive way. This timely book is appropriate for advanced undergraduate and graduate students seeking training in this area; researchers in biochemistry, organic geochemistry, and biogeochemistry; researchers working on aspects of organic cycling in aquatic ecosystems; and paleoceanographers, petroleum geologists, and ecologists. Provides a guide to the broad diversity of chemical biomarkers in aquatic environments The first textbook to be structured around the compounds themselves Describes the structure, biochemical synthesis, analysis, and reactivity of each class of biomarkers Offers a selection of relevant applications to aquatic systems, including lakes, rivers, estuaries, oceans, and paleoenvironments Demonstrates the utility of using organic molecules as tracers of processes occurring in aquatic ecosystems, both modern and ancient

Radiation Dose Reconstruction for Epidemiologic Uses

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309176832
Total Pages : 150 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Radiation Dose Reconstruction for Epidemiologic Uses by : National Research Council

Download or read book Radiation Dose Reconstruction for Epidemiologic Uses written by National Research Council and published by National Academies Press. This book was released on 1995-05-16 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Growing public concern about releases of radiation into the environment has focused attention on the measurement of exposure of people living near nuclear weapons production facilities or in areas affected by accidental releases of radiation. Radiation-Dose Reconstruction for Epidemiologic Uses responds to the need for criteria for dose reconstruction studies, particularly if the doses are to be useful in epidemiology. This book provides specific and practical recommendations for whether, when, and how studies should be conducted, with an emphasis on public participation. Based on the expertise of scientists involved in dozens of dose reconstruction projects, this volume: Provides an overview of the basic requirements and technical aspects of dose reconstruction. Presents lessons to be learned from dose reconstructions after Chernobyl, Three Mile Island, and elsewhere. Explores the potential benefits and limitations of biological markers. Discusses how to establish the "source term"â€"that is, to determine what was released. Explores methods for identifying the environmental pathways by which radiation reaches the body. Offers details on three major categories of dose assessment.

Radiation Proteomics

Author : Dariusz Leszczynski
Publisher : Springer Science & Business Media
ISBN 13 : 9400758960
Total Pages : 130 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Radiation Proteomics by : Dariusz Leszczynski

Download or read book Radiation Proteomics written by Dariusz Leszczynski and published by Springer Science & Business Media. This book was released on 2013-02-03 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods of proteomics have been shown to be powerful tools in search of target proteins – proteins that respond in cells to an internal or an external stimulus. Proteomics is widely used in biomedical research. However, in radiation biology research, following exposures of living matter to low doses of either ionizing or non-ionizing radiation, proteomics approach is only very slowly gaining support. This book, by presenting the current status of the use of proteomics in radiation biology, will help to attract attention to the field of radiation proteomics.

Reducing Environmental Cancer Risk

Author : Suzanne H. Reuben
Publisher : DIANE Publishing
ISBN 13 : 1437934218
Total Pages : 240 pages
Book Rating : 4.4/5 (379 download)

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Book Synopsis Reducing Environmental Cancer Risk by : Suzanne H. Reuben

Download or read book Reducing Environmental Cancer Risk written by Suzanne H. Reuben and published by DIANE Publishing. This book was released on 2010-10 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.

Biomarkers

Author : Vishal S. Vaidya
Publisher : John Wiley & Sons
ISBN 13 : 9780470918555
Total Pages : 632 pages
Book Rating : 4.9/5 (185 download)

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Book Synopsis Biomarkers by : Vishal S. Vaidya

Download or read book Biomarkers written by Vishal S. Vaidya and published by John Wiley & Sons. This book was released on 2010-10-28 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an introduction to the field of biomarkers, how they have been and can be used, and how different approaches can be used to identify, characterize, and monitor biomarkers. The book has chapters on topics including HIV, Cancer, Parkinson’s, vascular injury, environmental exposure. A following section discusses the technologies (diagnostics and assays) to detect biomarkers and authors have emphasized the preclinical and clinical manifestation of the injury/disease process.

Analysis of Cancer Risks in Populations Near Nuclear Facilities

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309255716
Total Pages : 424 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Analysis of Cancer Risks in Populations Near Nuclear Facilities by : National Research Council

Download or read book Analysis of Cancer Risks in Populations Near Nuclear Facilities written by National Research Council and published by National Academies Press. This book was released on 2012-06-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.

Health Risks from Exposure to Low Levels of Ionizing Radiation

Author : Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation
Publisher : National Academies Press
ISBN 13 : 0309133343
Total Pages : 422 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Health Risks from Exposure to Low Levels of Ionizing Radiation by : Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation

Download or read book Health Risks from Exposure to Low Levels of Ionizing Radiation written by Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation and published by National Academies Press. This book was released on 2006-03-23 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.

Clearing the Smoke

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309072824
Total Pages : 657 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Clearing the Smoke by : Institute of Medicine

Download or read book Clearing the Smoke written by Institute of Medicine and published by National Academies Press. This book was released on 2001-10-17 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite overwhelming evidence of tobacco's harmful effects and pressure from anti-smoking advocates, current surveys show that about one-quarter of all adults in the United States are smokers. This audience is the target for a wave of tobacco products and pharmaceuticals that claim to preserve tobacco pleasure while reducing its toxic effects. Clearing the Smoke addresses the problems in evaluating whether such products actually do reduce the health risks of tobacco use. Within the context of regulating such products, the committee explores key questions: Does the use of such products decrease exposure to harmful substances in tobacco? Is decreased exposure associated with decreased harm to health? Are there surrogate indicators of harm that could be measured quickly enough for regulation of these products? What are the public health implications? This book looks at the types of products that could reduce harm and reviews the available evidence for their impact on various forms of cancer and other major ailments. It also recommends approaches to governing these products and tracking their public health effects. With an attitude of healthy skepticism, Clearing the Smoke will be important to health policy makers, public health officials, medical practitioners, manufacturers and marketers of "reduced-harm" tobacco products, and anyone trying to sort through product claims.

From Habitability to Life on Mars

Author : Nathalie A. Cabrol
Publisher : Elsevier
ISBN 13 : 0128099364
Total Pages : 390 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis From Habitability to Life on Mars by : Nathalie A. Cabrol

Download or read book From Habitability to Life on Mars written by Nathalie A. Cabrol and published by Elsevier. This book was released on 2018-07-10 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: From Habitability to Life on Mars explores the current state of knowledge and questions on the past habitability of Mars and the role that rapid environmental changes may have played in the ability of prebiotic chemistry to transition to life. It investigates the role that such changes may have played in the preservation of biosignatures in the geological record and what this means for exploration strategies. Throughout the book, the authors show how the investigation of terrestrial analogs to early Martian habitats under various climates and environmental extremes provide critical clues to understand where, what and how to search for biosignatures on Mars. The authors present an introduction to the newest developments and state-of-the-art remote and in situ detection strategies and technologies that are being currently developed to support the upcoming ExoMars and Mars 2020 missions. They show how the current orbital and ground exploration is guiding the selection for future landing sites. Finally, the book concludes by discussing the critical question of the implications and ethics of finding life on Mars. Edited by the lead on a NASA project that searches for habitability and life on Mars leading to the Mars 2020 mission Presents the evidence, questions and answers we have today (including a summary of the current state of knowledge in advance of the ESA ExoMars and NASA Mars 2020 missions) Includes contributions from authors directly involved in past, current and upcoming Mars missions Provides key information as to how Mars rovers, such as ExoMars and Mars 2020, will address the search for life on Mars with their instrumentation