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Author : Raymond W. Ruddon
Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 618 pages
Book Rating : 4.3/5 (91 download)
Download or read book Biological Markers of Neoplasia written by Raymond W. Ruddon and published by Elsevier Publishing Company. This book was released on 1978 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Prakash Chandra
Publisher : Springer Science & Business Media
ISBN 13 : 1468444549
Total Pages : 631 pages
Book Rating : 4.4/5 (684 download)
Download or read book Biochemical and Biological Markers of Neoplastic Transformation written by Prakash Chandra and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is arecord of the proceedings of a NATO Advanced Study institute on "Biochemical and Bio logical Markers of Neoplastic Transformation" held September 28 - October 8, 1981, at Corfu, Greece. As early as 1860, Rudolf Virchow provided the first genetic concept of cancer by postulating "Omnia ceZZuZa e ceZZuZa ejusdem generis", a modification of the then exisiting cell theory "Omnis ceZZuZa e ceZZuZa". Thus, the idea that all cells originate from the parent cell was extended to the idea that all cancer cells come from the "paren t" cancer cello But how the first cancer cell arose, or in other words, how anormal cell changed to a cancer cell, is, even after 120 years, a mystery. Experimental studies of the past have convinced us that a number of factors contribute to the neoplastic transformation of anormal cell, but our knowledge on the mechanisms involved in this process is still in an embryonic state. In the last few years, however, this field has witnessed a most remarkable advancement cata lyzed by the development of modern technology in the al lied fields of immunology, the production of mono clonal antibodies, molecular biology, and sequencing v PREFACE and cloning of ONC genes. Presently, it is becoming more and more evident to the wishful mind of those engaged in this research that we are approaching a turning point. Thus, an assessment of the present situa tion will be most desirable at this time
Author : Debmalya Barh
Publisher : CRC Press
ISBN 13 : 1466584289
Total Pages : 992 pages
Book Rating : 4.4/5 (665 download)
Download or read book Cancer Biomarkers written by Debmalya Barh and published by CRC Press. This book was released on 2014-01-30 with total page 992 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gleaning information from more than 100 experts in the field of cancer diagnosis, prognosis, and therapy worldwide, Cancer Biomarkers: Non-Invasive Early Diagnosis and Prognosis determines the significance of clinical validation approaches for several markers. This book examines the use of noninvasive or minimally invasive molecular cancer markers that are under development or currently in use. It deals with a majority of commonly prevalent cancers and can help anyone working in the health-care industry to recommend or develop early diagnostics, at-risk tests, and prognostic biomarkers for various cancers. It explores the practice of determining biomarkers by their characteristics and relative methodologies, and presents the most recent data as well as a number of current and upcoming early diagnostic noninvasive molecular markers for many common cancers. It also considers the sensitivity and specificity of markers, biomarker market, test providers, and patent information. Approximately 30-35 Cancer Specific Noninvasive Molecular Diagnostic Markers in a Single Volume The book details the general and technical aspects of noninvasive cancer markers. It covers imaging, cutting-edge molecular technologies for biomarker development, and noninvasive or minimally invasive sources of molecular markers, as well as quality control and ethical issues in cancer biomarker discovery. It also provides a detailed account of brain, head and neck, and oral cancer markers, and provides information on a number of gastrointestinal cancers, lung cancer, and mesothelioma markers. Emphasizes the Importance of Volatile Markers in Early Cancer Diagnosis Presents noninvasive early molecular markers in urological cancers Describes gynecological and endocrine cancer markers Details noninvasive markers of breast, ovarian, cervical, and thyroid cancers Addresses hematological malignancies Contains information on noninvasive molecular markers in myelodysplastic syndromes, acute myeloid leukemia, Hodgkin’s lymphoma, and multiple myeloma Provides comprehensive information on diagnostic and prognostic biomarkers in cutaneous melanoma This text considers molecular technologies for biomarker development, noninvasive or minimally invasive sources of molecular markers, and quality control and ethical issues in cancer biomarker discovery.
Author : P. Toniolo
Publisher :
ISBN 13 :
Total Pages : 340 pages
Book Rating : 4.:/5 (318 download)
Download or read book Application of Biomarkers in Cancer Epidemiology written by P. Toniolo and published by . This book was released on 1997 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication originates from an international workshop which addresses a range of methodological issues underlying the use of biological markers of exposure, biological effects and individual susceptibility in cancer epidemiology. It includes a report of the workshop, with a general discussion and recommendation on epidemiology. a series of peer-reviewed authored contributors provide a more personal view on the most important aspects by key researchers.
Author :
Publisher :
ISBN 13 : 9780444002921
Total Pages : 0 pages
Book Rating : 4.0/5 (29 download)
Download or read book Biological Markers of Neoplasia written by and published by . This book was released on with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Raymond W. Ruddon
Publisher :
ISBN 13 :
Total Pages : 590 pages
Book Rating : 4.:/5 (732 download)
Download or read book Biological Markers of Neoplasia written by Raymond W. Ruddon and published by . This book was released on 1978 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : F. Cimino
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110846519
Total Pages : 940 pages
Book Rating : 4.1/5 (18 download)
Download or read book Human Tumor Markers written by F. Cimino and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-07-22 with total page 940 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Human Tumor Markers".
Author : Gerhard Seifert
Publisher : Springer Science & Business Media
ISBN 13 : 3642713564
Total Pages : 402 pages
Book Rating : 4.6/5 (427 download)
Download or read book Morphological Tumor Markers written by Gerhard Seifert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: New methods in immunocytochemistry and hybridization techniques enable the pathologist active in diagnosis to clarify more effectively problems in the classification and prognosis of tumors. By adopting these methods into his diagnostic repertoire it will be possible to create a closer, more productive connection between morphological diagnosis and clinical work. This volume gives the reader an up-to-date general survey from international experts of the method, technique and practical application of these new procedures.
Author : Pinki Singh
Publisher :
ISBN 13 :
Total Pages : 45 pages
Book Rating : 4.:/5 (72 download)
Download or read book Identification of Biological Markers for Prostatic Neoplasia Using Bioinformatics Approaches written by Pinki Singh and published by . This book was released on 2005 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Dan Hellberg
Publisher : Nova Science Publishers
ISBN 13 : 9781607413820
Total Pages : 0 pages
Book Rating : 4.4/5 (138 download)
Download or read book Histological and Serological Tumor Markers and Gene Expression and Their Clinical Usefulness in Cancers written by Dan Hellberg and published by Nova Science Publishers. This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The number of commercially available antibodies for the detection of biological markers, tumor markers, by immunohistochemistry or serological methods in cancer are rapidly increasing. Results in different studies are often contradictory and the usefulness of single tumor markers in different cancer types is unclear. An increasing number of studies on genetic "fingerprints" are being reported. This book represents the most comprehensive and up-to-date publication on histological and serological tumor markers, also commenting recent genetic studies. Sixteen major cancer types and an additional chapter on HIV-related cancers are reviewed by more than 40 authors. These are cancer of the breast, lung, esophagus, stomach, pancreas, liver, colon, rectum, anus, skin, brain, prostate, penis, ovary, uterus, uterine cervix and HIV-related cancers. The authors are active and respected researchers, experts in their fields. Tumor markers will be evaluated for clinical usefulness in diagnostics, prognosis and therapy. Definitive present usefulness is given for the specific cancer types and their purpose of use. Tumor markers that are still being evaluated but of possible future clinical importance are discussed. The index will make it easy to find a particular tumor marker and compare studies on different cancer types. The book is meant to inspire clinical and laboratory management as well as planning research and evaluation of results. Thus, oncologists, pathologists and other physicians who are involved in patients with cancer will find it useful.
Author : Bela Bodey
Publisher : Springer Science & Business Media
ISBN 13 : 1402028040
Total Pages : 365 pages
Book Rating : 4.4/5 (2 download)
Download or read book Molecular Markers of Brain Tumor Cells written by Bela Bodey and published by Springer Science & Business Media. This book was released on 2006-03-06 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Childhood brain tumors are a diverse group of diseases characterized by the abnormal growth of tissue contained within the skull. Other than leukemia and lymphoma, brain tumors are the most common type of neoplasms that occur in children. The leading cause of death from childhood neoplasms among persons up to 19 years is brain tumors. As such, this book is a review of the most recent molecular biological research concerning brain tumors with references and comparisons to a variety of neoplastic disorders. The book then uses this information to foreshadow the direction that future anti-neoplastic therapies will take. Because of the wide spectrum of the objectives of the book, any individual involved in cancer research will greatly benefit from the work. Histopathologists, neuropathologists, clinical and research oncologists, and medical students will find this book to be an invaluable resource as a reference guide. Patients and their families will also find the book useful as it offers a comprehensive update on new, non-classical therapeutic modality options and contains a detailed description and analysis of brain tumors. Such an endeavor has yet to be undertaken by any other book and may prove to be the most comprehensive book on brain tumors thus far.
Author : Deborah Chang
Publisher : Nova Publishers
ISBN 13 : 9781600215445
Total Pages : 328 pages
Book Rating : 4.2/5 (154 download)
Download or read book Tumor Markers Research Focus written by Deborah Chang and published by Nova Publishers. This book was released on 2007 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumour markers are molecules occurring in blood or tissue that are associated with cancer, and whose measurement or identification is useful in patient diagnosis or clinical management. This book analyses potential signals of cancerous tumours, otherwise known as markers or indicators. This includes, direct and rapid determination of cancer antigen, potential tumour markers for cholangiocarcinoma, melanoma inhibitory activity, metastatic uveal melanoma, measurement of tumour oxygenation, bladder cancer markers, epithelial cell adhesion and progression markers in prostate tumours.
Author : Saad Eissa
Publisher : Hodder Education
ISBN 13 :
Total Pages : 424 pages
Book Rating : 4.3/5 (91 download)
Download or read book Tumor Markers written by Saad Eissa and published by Hodder Education. This book was released on 1998 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive introduction to the expression of tumor markers in association with various neoplasms, the methods used in their detection and their clinical relevance to the diagnosis and treatment of cancer. It will be an invaluable guide for clinicians, pathologists and research workers requiring an in-depth introduction to this subject and, with sections devoted to the exploitation of new techniques in immunohistochemistry, flow cytomtry, cancer genetics and molecular biology for the identification of tumor markers, can also be used as a laboratory reference.
Author : Stuart A. Aaronson
Publisher : Springer Science & Business Media
ISBN 13 : 1468448560
Total Pages : 366 pages
Book Rating : 4.4/5 (684 download)
Download or read book Genetic and Phenotypic Markers of Tumors written by Stuart A. Aaronson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of tumor markers is not only one of the most important but also one that offers one of the richest perspectives in biology and clinical oncology. The aim of scientists in this field is to adduce evidence of a property that is typical of and exclusive to tumor cells, and which is easy to determine, in order to immediately recognize, or even better, to foresee, neoplastic transformations. Unfortunately, despite the large number of scientists and laboratories engaged in this work, the ideal tumor marker has not yet been identified. However, it is worth noting that new trends in molecular biology and immunovirology have recently opened up new avenues that may lead to the eventual resolution of this problem. In this book, different approaches to the identification of tumor markers, from the points of view of biochemistry, immunology, and molecular biology, are compared in order to explore possible interrelationships and to stimulate scientific collaboration among scientists active in these fields, both in basic research and in clinical applications. We wish to thank all the contributors and also the publisher, especially Dr. Robert Andrews, for making the publication of this book possible.
Author : Harry A. Milman
Publisher : Springer Science & Business Media
ISBN 13 : 1461337909
Total Pages : 505 pages
Book Rating : 4.4/5 (613 download)
Download or read book Application of Biological Markers to Carcinogen Testing written by Harry A. Milman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Giampietro Gasparini
Publisher : Springer Science & Business Media
ISBN 13 : 159259915X
Total Pages : 335 pages
Book Rating : 4.5/5 (925 download)
Download or read book Biomarkers in Breast Cancer written by Giampietro Gasparini and published by Springer Science & Business Media. This book was released on 2008-01-17 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.
Author : Stewart Sell
Publisher : Springer Science & Business Media
ISBN 13 : 1461204011
Total Pages : 537 pages
Book Rating : 4.4/5 (612 download)
Download or read book Serological Cancer Markers written by Stewart Sell and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book-the fourth volume of a series on Can cer Markers-is intended to provide an updated "status report" on today's use of cancer markers in the diagnosis and monitoring of can cer, with an emphasis on cancer markers detected in the serum. It has been 7 years since the publication of the last volume in this series. The 1980, 1982, and 1985 volumes covered the development of cancer markers, not only in their roles of unraveling the basic biology of can cer, but also as increasingly important players in the management of patients with cancer. During the last 7 years we have seen the applica tion of a number of markers identified by monoclonal antibodies, as well as the beginnings of the use of genetic markers defined by mo lecular probes. Measurements of oncogenes in tissues or cells prom ise many applications for the future, but as yet, these genes have not shown to be useful as serum markers of cancer. The commercial interest in serum markers for cancer, particu larly for the diagnosis and monitoring of tumor patients, is indicated in Chapter 24 by Owen, where the total worldwide market for cancer markers is projected to increase from $148 million in 1988 to $232 million in 1993. The degree of research interest in cancer markers is reflected in the fact that in 1988 a separate category for tumor mark ers was added to Index Medicus.
