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Bioinformatics For Oral Cancer
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Book Synopsis Bioinformatics for Oral Cancer by : Mahesh KP
Download or read book Bioinformatics for Oral Cancer written by Mahesh KP and published by CRC Press. This book was released on 2024-05-31 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Amid the rising global concern of oral cancer, this book provides a compelling exploration of the intricate oral cavity, focused on shedding light on early diagnosis and addressing outdated paradigms, it delves into the persistent challenges of oral premalignant lesions. Tailored for both beginners and researchers, its six chapters encompass the spectrum of genome sequencing, diagnostic biomarkers, gene expression, and more. Discover a fusion of basic and clinical sciences, aiming to invigorate the study of bioinformatics and oral cancer, and ultimately improve survival rates. Bioinformatics for Oral Cancer: Current Insights and Advances serves as a comprehensive guide, offering a deep dive into the multifaceted landscape of oral cancer research and bioinformatics. Within its pages, readers will uncover a wealth of knowledge, starting with foundational chapters introducing bioinformatics and establishing the backdrop of oral cancer. The book then progresses into the realm of diagnostic biomarkers, revealing cutting-edge methodologies for their identification in the context of oral cancer. The book’s keen focus extends to gene expression profiles and the intricacies of gene sequencing in the context of oral cancer progression. By systematically unravelling these critical aspects, the book bridges the gap between basic and clinical sciences, equipping readers with a holistic understanding of bioinformatics’ pivotal role in enhancing our grasp of oral cancer’s complexities. By deciphering the enigmatic landscape of oral premalignant lesions, the book equips clinicians and researchers with tools to predict malignant potentials. Its meticulous exploration of gene expression profiles and sequencing promises to reshape early detection strategies, propelling the field towards improved diagnosis and treatment outcomes.
Book Synopsis Application of Bioinformatics in Cancers by : Chad Brenner
Download or read book Application of Bioinformatics in Cancers written by Chad Brenner and published by MDPI. This book was released on 2019-11-20 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of 25 research papers comprised of 22 original articles and 3 reviews is brought together from international leaders in bioinformatics and biostatistics. The collection highlights recent computational advances that improve the ability to analyze highly complex data sets to identify factors critical to cancer biology. Novel deep learning algorithms represent an emerging and highly valuable approach for collecting, characterizing and predicting clinical outcomes data. The collection highlights several of these approaches that are likely to become the foundation of research and clinical practice in the future. In fact, many of these technologies reveal new insights about basic cancer mechanisms by integrating data sets and structures that were previously immiscible. Accordingly, the series presented here bring forward a wide range of artificial intelligence approaches and statistical methods that can be applied to imaging and genomics data sets to identify previously unrecognized features that are critical for cancer. Our hope is that these articles will serve as a foundation for future research as the field of cancer biology transitions to integrating electronic health record, imaging, genomics and other complex datasets in order to develop new strategies that improve the overall health of individual patients.
Book Synopsis Analysis and Prediction of Highly-expressive Genes Induced Signaling Pathways in the EGFR Overexpressed Oral Cancer Cells by Bioinformatics Tools by :
Download or read book Analysis and Prediction of Highly-expressive Genes Induced Signaling Pathways in the EGFR Overexpressed Oral Cancer Cells by Bioinformatics Tools written by and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Biology of Oral Cancer by : Prakash S. Bisen
Download or read book Biology of Oral Cancer written by Prakash S. Bisen and published by CRC Press. This book was released on 2013-07-15 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite a decline in developed countries, cancer has consistently maintained its status as one of the top killers since time immemorial. Exploring cancer management and treatment at the molecular level, Biology of Oral Cancer: Key Apoptotic Regulators presents a key molecular event-apoptosis-in relation to genesis and progression of oral cancer. Th
Book Synopsis Genomics, Personalized Medicine and Oral Disease by : Stephen T. Sonis, DMD, DMSc
Download or read book Genomics, Personalized Medicine and Oral Disease written by Stephen T. Sonis, DMD, DMSc and published by Springer. This book was released on 2015-09-17 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this book is to catalyze the application of genomics to the diagnosis and treatment of oral diseases by comprehensively presenting focused discussions on the current state of knowledge. The first section book provides basic information about genetics, genomics and personalized medicine and the informatical methods available to apply and organize genetic data so that it has clinical relevance. Recognizing the genetic robustness of the oral cavity, the introductory section includes chapters on the oral micro biome and host genomics and response to infectious agents. The next two sections contain chapters which describe the genomics of specific oral diseases and conditions, including the genetic basis for mechanism and risk of treatment toxicities associated with cancer therapy and bisphosphonates. Four chapters focus on gene-based therapies and the pharmacogenomics applied to oral disease. The final chapter presents a provocative summary which describes a comprehensive vision of the melding of genomics to personalized medicine and the potential actionable outcomes that will likely affect clinical practice in the upcoming years.
Book Synopsis Bioinformatics in Cancer and Cancer Therapy by : Gavin J. Gordon
Download or read book Bioinformatics in Cancer and Cancer Therapy written by Gavin J. Gordon and published by Springer Science & Business Media. This book was released on 2008-10-25 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinformatics can be loosely defined as the collection, classification, storage, and analysis of biochemical and biological information using computers and mathematical algorithms. Bioinformatics represents a marriage of biology, medicine, computer science, physics, and mathematics, fields of study that have historically existed as mutually exclusive disciplines. Edited by Gavin Gordon, Bioinformatics in Cancer and Cancer Therapy, the focus of this book is to provide a historical and technical perspective on the analytical techniques, methodologies, and platforms used in bioinformatics experiments, to show how a bioinformatics approach has been used to characterize various cancer-related processes, and to demonstrate how a bioinformatics approach is being used to bridge basic science and the clinical arena to positively impact patient care and management.
Download or read book Cancer Bioinformatics written by Ying Xu and published by Springer. This book was released on 2014-08-30 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a framework for computational researchers studying the basics of cancer through comparative analyses of omic data. It discusses how key cancer pathways can be analyzed and discovered to derive new insights into the disease and identifies diagnostic and prognostic markers for cancer. Chapters explain the basic cancer biology and how cancer develops, including the many potential survival routes. The examination of gene-expression patterns uncovers commonalities across multiple cancers and specific characteristics of individual cancer types. The authors also treat cancer as an evolving complex system, explore future case studies, and summarize the essential online data sources. Cancer Bioinformatics is designed for practitioners and researchers working in cancer research and bioinformatics. It is also suitable as a secondary textbook for advanced-level students studying computer science, biostatistics or biomedicine.
Book Synopsis Bioinformatics for Diagnosis, Prognosis and Treatment of Complex Diseases by : Bairong Shen
Download or read book Bioinformatics for Diagnosis, Prognosis and Treatment of Complex Diseases written by Bairong Shen and published by Springer Science & Business Media. This book was released on 2013-11-25 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book introduces the bioinformatics tools, databases and strategies for the translational research, focuses on the biomarker discovery based on integrative data analysis and systems biological network reconstruction. With the coming of personal genomics era, the biomedical data will be accumulated fast and then it will become reality for the personalized and accurate diagnosis, prognosis and treatment of complex diseases. The book covers both state of the art of bioinformatics methodologies and the examples for the identification of simple or network biomarkers. In addition, bioinformatics software tools and scripts are provided to the practical application in the study of complex diseases. The present state, the future challenges and perspectives were discussed. The book is written for biologists, biomedical informatics scientists and clinicians, etc. Dr. Bairong Shen is Professor and Director of Center for Systems Biology, Soochow University; he is also Director of Taicang Center for Translational Bioinformatics.
Book Synopsis Cancer Systems Biology, Bioinformatics and Medicine by : Alfredo Cesario
Download or read book Cancer Systems Biology, Bioinformatics and Medicine written by Alfredo Cesario and published by Springer Science & Business Media. This book was released on 2011-08-21 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: This teaching monograph on systems approaches to cancer research and clinical applications provides a unique synthesis, by world-class scientists and doctors, of laboratory, computational, and clinical methods, thereby establishing the foundations for major advances not possible with current methods. Specifically, the book: 1) Sets the stage by describing the basis of systems biology and bioinformatics approaches, and the clinical background of cancer in a systems context; 2) Summarizes the laboratory, clinical, data systems analysis and bioinformatics tools, along with infrastructure and resources required; 3) Demonstrates the application of these tools to cancer research; 4) Extends these tools and methods to clinical diagnosis, drug development and treatment applications; and 5) Finishes by exploring longer term perspectives and providing conclusions. This book reviews the state-of-the-art, and goes beyond into new applications. It is written and highly referenced as a textbook and practical guide aimed at students, academics, doctors, clinicians, industrialists and managers in cancer research and therapeutic applications. Ideally, it will set the stage for integration of available knowledge to optimize communication between basic and clinical researchers involved in the ultimate fight against cancer, whatever the field of specific interest, whatever the area of activity within translational research.
Book Synopsis Cancer Bioinformatics by : Sylvia Nagl
Download or read book Cancer Bioinformatics written by Sylvia Nagl and published by . This book was released on 2006-03-06 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The development and application of bioinformatics tools to basic and translational cancer research is, in fact, a rapidly expanding field that deserves a timely review. Therefore, a publication of this type is needed. The editors have done an excellent job in recruiting well-established scientists to author the various chapters of the book." —Dieter Naf, Jackson Laboratory, USA Cancer bioinformatics is now emerging as a new interdisciplinary field, which is facilitating an unprecedented synthesis of knowledge arising from the life and clinical sciences. This groundbreaking title provides a comprehensive and up-to-date account of the enormous range of bioinformatics for cancer therapy development from the laboratory to clinical trials. It functions as a guide to integrated data exploitation and synergistic knowledge discovery, and support the consolidation of the interdisciplinary research community involved.
Book Synopsis Bioinformatics for Cancer Immunotherapy by : Sebastian Boegel
Download or read book Bioinformatics for Cancer Immunotherapy written by Sebastian Boegel and published by Humana. This book was released on 2021-03-17 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on a variety of in silico protocols of the latest bioinformatics tools and computational pipelines developed for neo-antigen identification and immune cell analysis from high-throughput sequencing data for cancer immunotherapy. The chapters in this book cover topics that discuss the two emerging concepts in recognition of tumor cells using endogenous T cells: cancer vaccines against neo-antigens presented on HLA class I and II alleles, and checkpoint inhibitors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Bioinformatics for Cancer Immunotherapy: Methods and Protocols is a valuable research tool for any scientist and researcher interested in learning more about this exciting and developing field.
Book Synopsis Cancer Systems Biology, Bioinformatics and Medicine by : Alfredo Cesario
Download or read book Cancer Systems Biology, Bioinformatics and Medicine written by Alfredo Cesario and published by Springer. This book was released on 2011-08-21 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This teaching monograph on systems approaches to cancer research and clinical applications provides a unique synthesis, by world-class scientists and doctors, of laboratory, computational, and clinical methods, thereby establishing the foundations for major advances not possible with current methods. Specifically, the book: 1) Sets the stage by describing the basis of systems biology and bioinformatics approaches, and the clinical background of cancer in a systems context; 2) Summarizes the laboratory, clinical, data systems analysis and bioinformatics tools, along with infrastructure and resources required; 3) Demonstrates the application of these tools to cancer research; 4) Extends these tools and methods to clinical diagnosis, drug development and treatment applications; and 5) Finishes by exploring longer term perspectives and providing conclusions. This book reviews the state-of-the-art, and goes beyond into new applications. It is written and highly referenced as a textbook and practical guide aimed at students, academics, doctors, clinicians, industrialists and managers in cancer research and therapeutic applications. Ideally, it will set the stage for integration of available knowledge to optimize communication between basic and clinical researchers involved in the ultimate fight against cancer, whatever the field of specific interest, whatever the area of activity within translational research.
Book Synopsis Cancer Bioinformatics by : Alexander Krasnitz
Download or read book Cancer Bioinformatics written by Alexander Krasnitz and published by . This book was released on 2018 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cancer Bioinformatics: Bioinformatic Methods, Network Biomarkers and Precision Medicine by : Applied Research Applied Research Press
Download or read book Cancer Bioinformatics: Bioinformatic Methods, Network Biomarkers and Precision Medicine written by Applied Research Applied Research Press and published by . This book was released on 2015-11-05 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: The "Cancer bioinformatics" thematic series focuses on the latest developments in the emerging field of systems clinical medicine in cancer which integrates systems biology, clinical science, omics-based technology, bioinformatics and computational science to improve diagnosis, therapies and prognosis of cancer. Topics include: Improving the prediction of the functional impact of cancer mutations by baseline tolerance transformation; Cascaded discrimination of normal, abnormal, and confounder classes in histopathology: Gleason grading of prostate cancer; A molecular computational model improves the preoperative diagnosis of thyroid nodules; A systems biology approach to the global analysis of transcription factors in colorectal cancer; Cancer bioinformatics: A new approach to systems clinical medicine; A unified computational model for revealing and predicting subtle subtypes of cancers; Prognostic gene signatures for patient stratification in breast cancer - accuracy, stability and interpretability of gene selection approaches using prior knowledge on protein-protein interactions; A new analysis approach of epidermal growth factor receptor pathway activation patterns provides insights into cetuximab resistance mechanisms in head and neck cancer; Gene regulatory network inference: evaluation and application to ovarian cancer allows the prioritization of drug targets; Gene expression signatures modulated by epidermal growth factor receptor activation and their relationship to cetuximab resistance in head and neck squamous cell carcinoma; A dynamic model for tumour growth and metastasis formation; Synthetic Lethal Screen Identifies NF-kappaB as a Target for Combination Therapy with Topotecan for patients with Neuroblastoma.
Book Synopsis Identifiying Potential Biomarkers in the Secretome of Oral Cancer Cell Lines by Comparative Proteomic Analysis by : Hong Yun Chang
Download or read book Identifiying Potential Biomarkers in the Secretome of Oral Cancer Cell Lines by Comparative Proteomic Analysis written by Hong Yun Chang and published by . This book was released on 2013 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Oral Precancer written by Peter Thomson and published by John Wiley & Sons. This book was released on 2012-01-30 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Without early detection, oral cancer is deadly. Protect your patients by applying the latest clinical interventions. Rates of new oral cancer cases continue to increase and mortality rates remain alarmingly high. Oral cancer may be preceded by clinically identifiable precancerous changes in the oral mucosa, which offer a therapeutic window of opportunity to intervene and halt disease progression to carcinoma development. Written and edited by prominent researchers in the field, Oral Precancer: Reviews current scientific research on precancer conditions of the oral cavity providing evidence-based analysis of the nature and behavior of potentially malignant and deforming oral diseases Explains the principles of prevention, diagnosis and management of potentially malignant disorders of the oral cavity Details a practical and reliable interventional treatment strategy to facilitate early diagnosis and effective treatment of both precancer and early invasive carcinoma Contains a chapter devoted to illustrative case histories, high-quality, color, clinical photos, reference sections in each chapter listing relevant review articles, and more From start to finish, Oral Precancer offers undergraduate students, clinicians, and professors an invaluable resource to minimise the morbidity and mortality of this most significant and life threatening of oral conditions.
Book Synopsis Oral Complications of Cancer and Its Management by : Andrew Davies
Download or read book Oral Complications of Cancer and Its Management written by Andrew Davies and published by Oxford University Press. This book was released on 2010-02-25 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral complications are hugely important for those treating cancer patients, either as an indication of disease or as a symptom of the disease. This is the first book to focus on this unique area of cancer care, providing international, evidence-based, clinical guidance for the whole team involved in treating the cancer patient with oral problems.
