Biofilms in Human Diseases: Treatment and Control

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Publisher : Springer Nature
ISBN 13 : 3030307573
Total Pages : 318 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Biofilms in Human Diseases: Treatment and Control by : Sunil Kumar

Download or read book Biofilms in Human Diseases: Treatment and Control written by Sunil Kumar and published by Springer Nature. This book was released on 2019-11-19 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights treatment strategies for bacterial biofilms in connection with a variety of human diseases. In particular, it reviews bacterial biofilm formation and its mechanism. Topics covered include biofilms in human health, the role of biofilms in mediating human diseases, and methods for testing bacterial biofilms. Further sections concentrate on biofilm-mediated diseases in different parts of the human gastrointestinal tract, while therapeutic strategies for biofilm control and natural agents that disrupt bacterial biofilms are also covered. Readers will also find the latest advances in probiotics and biofilms, as well as the use of probiotics to counteract biofilm-associated infections. Biofilms and antimicrobial resistance are discussed. Subsequent chapters address the management of inflammatory bowel disease via probiotics biofilms, as well as the role of probiotics bacteria in the treatment of human diseases associated with bacterial biofilms. The book is chiefly intended for clinicians/scientists in the fields of medical microbiology, applied microbiology, biochemistry, and biotechnology.

Biofilm-Mediated Diseases: Causes and Controls

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Publisher : Springer Nature
ISBN 13 : 9811607451
Total Pages : 284 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Biofilm-Mediated Diseases: Causes and Controls by : Rina Rani Ray

Download or read book Biofilm-Mediated Diseases: Causes and Controls written by Rina Rani Ray and published by Springer Nature. This book was released on 2021-05-05 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the current concepts in biofilm formation and its implications in human health and disease. The initial chapters introduce the mechanisms of biofilm formation and its composition. Subsequently, the chapters discuss the role of biofilm in acute and chronic infections. It also explores the pivotal role of both innate and adaptive immunity on the course of biofilm infection. In addition, the book elucidates the bacterial biofilm formation on implantable devices and the current approaches to its treatment and prevention. It analyzes the possible relationship between antimicrobial resistance and biofilm formation. Finally, the book also summarizes the current state-of-the-art therapeutic approaches for preventing and treating biofilms. This book is a useful resource for researchers in the field of microbiology, clinical microbiology, and also medical practitioners.

Microbial Biofilms in Healthcare

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Publisher : MDPI
ISBN 13 : 303928410X
Total Pages : 166 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Microbial Biofilms in Healthcare by : Karen Vickery

Download or read book Microbial Biofilms in Healthcare written by Karen Vickery and published by MDPI. This book was released on 2020-03-16 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms are ubiquitous and their presence in industry can lead to production losses. However, nowhere do biofilms impact human health and welfare as much as those that are found contaminating the healthcare environment, surgical instruments, equipment, and medical implantable devices. Approximately 70% of healthcare-associated infections are due to biofilm formation, resulting in increased patient morbidity and mortality. Biofilms formed on medical implants are recalcitrant to antibiotic treatment, which leaves implant removal as the principal treatment option. In this book, we investigate the role of biofilms in breast and dental implant disease and cancer. We include in vitro models for investigating treatment of chronic wounds and disinfectant action against Candida sp. Also included are papers on the most recent strategies for treating biofilm infection ranging from antibiotics incorporated into bone void fillers to antimicrobial peptides and quorum sensing.

Microbial Biofilms

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Publisher : Elsevier
ISBN 13 : 0443192537
Total Pages : 291 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Microbial Biofilms by : Mukesh Kumar Yadav

Download or read book Microbial Biofilms written by Mukesh Kumar Yadav and published by Elsevier. This book was released on 2024-04-15 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research, such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection/and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms and the burden of biofilm associated infections. In addition, it highlights the various anti-biofilm strategies such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections and the escalation of antimicrobial resistance determinants. Microbial biofilms can be a serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms increases recovery time and the cost of disease management. Biofilms are resistant to known antibiotics and human defense mechanism. In addition, due to close proximity of microbes within biofilms, increase genetic transformation has been detected results in increases frequency of antibiotic gene spread. With the advancement in science and technology, novel strategies have been proposed to combat the impact of biofilms on human health. Fulfills the knowledge gap in biofilm study Focuses on new and emerging concepts in microbial biofilm research Highlights the various anti-biofilm strategies Provides concise, thorough and up-to-date information about the important role of microbial biofilms in human diseases

Biofilm Infections

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Publisher : Springer
ISBN 13 : 9781489982285
Total Pages : 0 pages
Book Rating : 4.9/5 (822 download)

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Book Synopsis Biofilm Infections by : Thomas Bjarnsholt

Download or read book Biofilm Infections written by Thomas Bjarnsholt and published by Springer. This book was released on 2014-10-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.

Recent Advances in Bacterial Biofilm Studies

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Publisher : BoD – Books on Demand
ISBN 13 : 1803567082
Total Pages : 184 pages
Book Rating : 4.8/5 (35 download)

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Book Synopsis Recent Advances in Bacterial Biofilm Studies by : Liang Wang

Download or read book Recent Advances in Bacterial Biofilm Studies written by Liang Wang and published by BoD – Books on Demand. This book was released on 2024-02-28 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial biofilm is a complex structure with diverse bacterial cells in a highly organized and ordered group within a matrix of extracellular polymeric substances they produce. Microbes attach to surfaces to develop biofilms, a sophisticated process regulated by factors such as nutritional status and biotic/abiotic surface features. An established biofilm structure mainly comprises bacterial cells, proteins, nucleic acid, and exo-polysaccharides that are extracellular macromolecules excreted as tightly bound layers in microbes, providing a perfect niche for bacteria to exchange genetic material between cells. In addition, bacterial cells in the matrix also communicate via quorum sensing, which greatly impacts biofilm processes. Under clinical circumstances, bacterial biofilm shows great resistance to antibiotics, disinfectants, and body defense systems, making it difficult for clinicians to eradicate and facilitate many infectious disease processes, leading to chronic infections of patients with long-term hospitalization and high mortality rates. Therefore, it is very important to understand the recent advances in forming, regulating, and eradicating biofilms in human infections to better prevent, control, and treat biofilm infections in humans. Written by an international team of basic and clinical researchers, the chapters of this book provide novel insights and advanced knowledge for life science researchers, clinical researchers, doctors, and other interested readers on some of the latest developments in biofilms.

Biofilms and Veterinary Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 3642212891
Total Pages : 268 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Biofilms and Veterinary Medicine by : Steven L. Percival

Download or read book Biofilms and Veterinary Medicine written by Steven L. Percival and published by Springer Science & Business Media. This book was released on 2011-08-08 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms are implicated in many common medical problems including urinary tract infections, catheter infections, middle-ear infections, dental plaque, gingivitis, and some less common but more lethal processes such as endocarditis and infections in cystic fibrosis. However, the true importance of biofilms in the overall process of disease pathogenesis has only recently been recognized. Bacterial biofilms are one of the fundamental reasons for incipient wound healing failure in that they may impair natural cutaneous wound healing and reduce topical antimicrobial efficiency in infected skin wounds. Their existence explains many of the enigmas of microbial infection and a better grasp of the process may well serve to establish a different approach to infection control and management. Biofilms and their associated complications have been found to be involved in up to 80% of all infections. A large number of studies targeted at the bacterial biofilms have been conducted, and many of them are referred to in this book, which is the first of its kind. These clinical observations emphasize the importance of biofilm formation to both superficial and systemic infections, and the inability of current antimicrobial therapies to ‘cure’ the resulting diseases even when the in vitro tests suggest that they should be fully effective. In veterinary medicine the concept of biofilms and their role in the pathogenesis of disease has lagged seriously behind that in human medicine. This is all the more extraordinary when one considers that much of the research has been carried out using veterinary species in experimental situations. The clinical features of biofilms in human medicine is certainly mimicked in the veterinary species but there is an inherent and highly regrettable indifference to the failure of antimicrobial therapy in many veterinary disease situations, and this is probably at its most retrograde in veterinary wound management. Biofilms and Veterinary Medicine is specifically focused on discussing the concerns of biofilms to health and disease in animals and provides a definitive text for veterinary practitioners, medical and veterinary students, and researchers.

Biofilms in Infection Prevention and Control

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Publisher : Academic Press
ISBN 13 : 0123977517
Total Pages : 394 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Biofilms in Infection Prevention and Control by : Steven L. Percival

Download or read book Biofilms in Infection Prevention and Control written by Steven L. Percival and published by Academic Press. This book was released on 2014-01-30 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms in Infection and Disease Control: A Healthcare Handbook outlines the scientific evidence and rationale for the prevention of infection, the role biofilms play in infection control, and the issues concerning their resistance to antimicrobials. This book provides practical guidance for healthcare and infection control professionals, as well as students, for preventing and controlling infection. Biofilms are the most common mode of bacterial growth in nature. Highly resistant to antibiotics and antimicrobials, biofilms are the source of more than 65 percent of health care associated infections (HCAI), which, according to the WHO, affect 1.4 million people annually. Biofilms are involved in 80 percent of all microbial infections in the body, including those associated with medical devices such as catheters, endotracheal tubes, joint prostheses, and heart valves. Biofilms are also the principle causes of infections of the middle-ear, dental caries, gingivitis, prostatitis and cystic fibrosis. Importantly, biofilms also significantly delay wound healing and reduce antimicrobial efficiency in at-risk or infected skin wounds. Provides specific procedures for controlling and preventing infection Includes case studies of HCAI, and identifies appropriate treatments Presents national government standards for infection prevention and control Includes extensive references and links to websites for further information

Bacterial Biofilms

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Publisher : Springer Science & Business Media
ISBN 13 : 3540754180
Total Pages : 302 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Bacterial Biofilms by : Tony Romeo

Download or read book Bacterial Biofilms written by Tony Romeo and published by Springer Science & Business Media. This book was released on 2008-02-26 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.

Medical Biofilms

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Publisher : John Wiley & Sons
ISBN 13 : 9780471988670
Total Pages : 328 pages
Book Rating : 4.9/5 (886 download)

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Book Synopsis Medical Biofilms by : Jana Jass

Download or read book Medical Biofilms written by Jana Jass and published by John Wiley & Sons. This book was released on 2003-04-02 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms are formed by microorganisms growing on surfaces and comprise a series of microcolonies interspersed with spaces through which fluids and other microorganisms move. In medicine, the primary problems are biofilms associated with implants: infections are increasingly difficult to treat with traditional antibiotics and removal of the implant often becomes essential, frequently leading to higher morbidity and mortality. This will be the first book dedicated to medical biofilms. It will cover much recent information on the problems of biofilms, how to detect them and how to control their presence.

Control of Biofilm Infections by Signal Manipulation

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Publisher : Springer Science & Business Media
ISBN 13 : 3540738533
Total Pages : 186 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Control of Biofilm Infections by Signal Manipulation by : Naomi Balaban

Download or read book Control of Biofilm Infections by Signal Manipulation written by Naomi Balaban and published by Springer Science & Business Media. This book was released on 2007-11-28 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: The number of patients affected by and dying from what can be considered as a "biofilm disease" is higher than heart disease and cancer combined. Thus, this is a hugely important work that describes the molecular mechanisms of cell-to-cell communication among bacterial cells in a biofilm, the development of antibiofilm inhibitors such as quorum-sensing inhibitors, and the use of biofilm inhibitors to prevent and treat bacterial infections in humans and other animals.

Antibiofilm Strategies

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Publisher : Springer Nature
ISBN 13 : 3031109929
Total Pages : 569 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis Antibiofilm Strategies by : Katharina Richter

Download or read book Antibiofilm Strategies written by Katharina Richter and published by Springer Nature. This book was released on 2022-09-28 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteria and fungi are able to aggregate together or on surfaces in densely packed microcolonies, facilitated by extracellular polymeric substances for cell protection and stability. These biofilms have proven to be extremely hard to eradicate and remove once established. In chronic infections, this condition can result in a high degree of morbidity and mortality as regular antibiotic treatments are ineffective against biofilms. In industrial facilities, the formation of biofilms can ruin production and result in enormous financial losses. In this book, the current state of antibiofilm research is presented by experts from around the world. Novel, cutting-edge techniques and new optimized strategies based on established methods are discussed in chapters focused on biofilm prevention, treatment and control for the application in clinical, industrial and veterinary settings. Antibiofilm strategies, such as chemical and enzymatic treatments, surface modification and coatings, quorum sensing inhibition and dispersal induction, phage therapy, cold plasma treatment, hyperbaric oxygen treatment, and metal-based nanomedicine are covered, among many others. This book contributes to the UN’s Sustainable Development Goal 3: Good Health and Well-Being and is a valuable resource for healthcare professionals, microbiologists, academics and for educators to inform curricula of universities and colleges.

Biofilms

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Publisher : CRC Press
ISBN 13 : 0203304721
Total Pages : 507 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Biofilms by : L V Evans

Download or read book Biofilms written by L V Evans and published by CRC Press. This book was released on 2003-09-02 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms affect the lives of all of us, growing as they do for example on our teeth (as plaque), on catheters and medical implants in our bodies, on our boats and ships, in food processing environments, and in drinking and industrial water treatment systems. They are highly complex biological communities whose detailed structure and functioning is only gradually being unravelled, with the development of increasingly sophisticated technology for their study. Biofilms almost always have a negative impact on human affairs (flocs in sewage treatment plants are a major exception) and a lot of research is being carried out to gain a better understanding of them, so that we will be in a better position to control them. This volume, with contributions by international experts from widely diverse areas of this field, presents a state-of-the-art picture of where we are at present in terms of our knowledge of biofilms, the techniques being used to study them, and possible strategies for controlling their growth more successfully. It should provide a valuable reference source for information on biofilms and their control for many years to come.

Microbial Biofilms in Healthcare: Formation, Prevention and Treatment

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Publisher :
ISBN 13 : 9783039284115
Total Pages : 166 pages
Book Rating : 4.2/5 (841 download)

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Book Synopsis Microbial Biofilms in Healthcare: Formation, Prevention and Treatment by : Karen Vickery

Download or read book Microbial Biofilms in Healthcare: Formation, Prevention and Treatment written by Karen Vickery and published by . This book was released on 2020 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms are ubiquitous and their presence in industry can lead to production losses. However, nowhere do biofilms impact human health and welfare as much as those that are found contaminating the healthcare environment, surgical instruments, equipment, and medical implantable devices. Approximately 70% of healthcare-associated infections are due to biofilm formation, resulting in increased patient morbidity and mortality. Biofilms formed on medical implants are recalcitrant to antibiotic treatment, which leaves implant removal as the principal treatment option. In this book, we investigate the role of biofilms in breast and dental implant disease and cancer. We include in vitro models for investigating treatment of chronic wounds and disinfectant action against Candida sp. Also included are papers on the most recent strategies for treating biofilm infection ranging from antibiotics incorporated into bone void fillers to antimicrobial peptides and quorum sensing.

Biofilm Eradication and Prevention

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Publisher : John Wiley & Sons
ISBN 13 : 1118043553
Total Pages : 339 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Biofilm Eradication and Prevention by : Tamilvanan Shunmugaperumal

Download or read book Biofilm Eradication and Prevention written by Tamilvanan Shunmugaperumal and published by John Wiley & Sons. This book was released on 2010-12-28 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilm Eradication and Preventions presents the basics of biofilm formation on medical devices, diseases related to this formation, and approaches pharmaceutical researchers need to take to limit this problem. Split into three parts, the first deals with the development and characterization of biofilm on the surfaces of implanted or inserted medical devices. Questions as to why biofilms form over medical device surfaces and what triggers biofilm formation are addressed. In the second section, the author discusses biofilm-mediated chronic infections occurred in various organs (eyes, mouth, wounds) and pharmaceutical and drug delivery knowledge gained from research in these area. The third part explores pharmaceutical approaches like lipid-and polymer-based drug delivery carriers for eradicating biofilm on device-related infections. In addition, this section also explores the topic of novel small molecule (like iron and its complexes/metal chelators) and a quorum-sensing inhibitors to control medical biofilm formation.

Antibiofilm Agents

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Publisher : Springer Science & Business Media
ISBN 13 : 3642538339
Total Pages : 495 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Antibiofilm Agents by : Kendra P. Rumbaugh

Download or read book Antibiofilm Agents written by Kendra P. Rumbaugh and published by Springer Science & Business Media. This book was released on 2014-05-08 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a survey of recent advances in the development of antibiofilm agents for clinical and environmental applications. The fact that microbes exist in structured communities called biofilms has slowly become accepted within the medical community. We now know that over 80% of all infectious diseases are biofilm-related; however, significant challenges still lie in our ability to diagnose and treat these extremely recalcitrant infections. Written by experts from around the globe, this book offers a valuable resource for medical professionals seeking to treat biofilm-related disease, academic and industry researchers interested in drug discovery and instructors who teach courses on microbial pathogenesis and medical microbiology.

Medical Implications of Biofilms

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Author :
Publisher : Cambridge University Press
ISBN 13 : 9781139438018
Total Pages : 340 pages
Book Rating : 4.4/5 (38 download)

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Book Synopsis Medical Implications of Biofilms by : Michael Wilson

Download or read book Medical Implications of Biofilms written by Michael Wilson and published by Cambridge University Press. This book was released on 2003-09-01 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human tissues often support large, complex microbial communities growing as biofilms that can cause a variety of infections. As a result of an increased use of implanted medical devices, the incidence of these biofilm-associated diseases is increasing: the non-shedding surfaces of these devices provide ideal substrata for colonisation by biofilm-forming microbes. The consequences of this mode of growth are far-reaching. As microbes in biofilms exhibit increased tolerance towards antimicrobial agents and decreased susceptibility to host defence systems, biofilm-associated diseases are becoming increasingly difficult to treat. Not surprisingly, therefore, interest in biofilms has increased dramatically. The application of microscopic and molecular techniques has revolutionised our understanding of biofilm structure, composition, organisation, and activities, resulting in important advances in the prevention and treatment of biofilm-related diseases. The purpose of this book, which was first published in 2003, is to bring these advances to the attention of clinicians and medical researchers.