Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Biofilm Associated On Antimicrobial Resistance And Its Recovery
Download Biofilm Associated On Antimicrobial Resistance And Its Recovery full books in PDF, epub, and Kindle. Read online Biofilm Associated On Antimicrobial Resistance And Its Recovery ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Biofilm Associated Antimicrobial Resistance and Its Recovery by : Dibyajit Lahiri
Download or read book Biofilm Associated Antimicrobial Resistance and Its Recovery written by Dibyajit Lahiri and published by CRC Press. This book was released on 2023-12-01 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biofilm is a collection of microbial cells that have adhered to biotic surfaces such as plant cuticles or animal epithelia, as well as abiotic surfaces such as rocky substratum or catheter exteriors. The life cycle of a microorganism includes the fundamental process of biofilm formation for survival in diverse and harsh environments since it is a protected mode of growth allowing colonisation of new habitats by dispersal of microbes from the microbial clusters. The biofilm bound microorganisms remain embedded in an extracellular polymeric matrix that protects the indwelling cells from surfactants, biocides, several invaders like protozoans, and defences offered by the hosts like phagocytic cells. The biofilm bound recalcitrant microbes induce chronic and nosocomial diseases, posing a serious threat to public health. It has been observed that various antimicrobial drugs are able to successfully remove the planktonic (freely suspended) states of microbes as compared to the sessile (substrate-bound) forms, thus resulting in the development of antimicrobial resistance. Modern pharmacological strategies targeting the biofilm matrix differ from the conventional methods of antibiotic usage. This includes the use of natural compounds such as plant bioactive molecules, antimicrobial peptides, green synthesised nanoparticles, or secondary metabolites from other organisms that not only prevent the rise of antimicrobial resistance but are also safe for the host tissues. Biofilm Associated Antimicrobial Resistance and Its Recovery provides a detailed and systematic review of alternative pharmacological developments in the field of biofilm research. Features: A narrative overview of the mechanism of biofilm formation and its role in the emergence of antimicrobial resistance. Recent research in the development of antibiofilm remedies involving biogenic compounds. Advancements in biofilm detection methodologies with cutting-edge technologies. This book serves as a resource for researchers who need to understand and analyze the progression of events during microbial biofilm formation, as well as design safer methodologies for its successful eradication. It may also be used as a textbook for a graduate level course in microbiology or microbial biotechnology.
Download or read book Bacterial Biofilms written by Tony Romeo and published by Springer Science & Business Media. This book was released on 2008-02-26 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.
Book Synopsis Biofilm Infections by : Thomas Bjarnsholt
Download or read book Biofilm Infections written by Thomas Bjarnsholt and published by Springer. This book was released on 2014-10-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.
Book Synopsis OECD Health Policy Studies Stemming the Superbug Tide by : OECD.
Download or read book OECD Health Policy Studies Stemming the Superbug Tide written by OECD. and published by Org. for Economic Cooperation & Development. This book was released on 2019-01-21 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial resistance (AMR) is a large and growing problem with the potential for enormous health and economic consequences, globally. As such, AMR has become a central issue at the top of the public health agenda of OECD countries and beyond. In this
Book Synopsis Mechanisms of antibiotic resistance by : Jun Lin
Download or read book Mechanisms of antibiotic resistance written by Jun Lin and published by Frontiers Media SA. This book was released on 2015-06-01 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.
Book Synopsis The Science and Applications of Synthetic and Systems Biology by : Institute of Medicine
Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Book Synopsis Antibiofilm Agents by : Kendra P. Rumbaugh
Download or read book Antibiofilm Agents written by Kendra P. Rumbaugh and published by Springer Science & Business Media. This book was released on 2014-05-08 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a survey of recent advances in the development of antibiofilm agents for clinical and environmental applications. The fact that microbes exist in structured communities called biofilms has slowly become accepted within the medical community. We now know that over 80% of all infectious diseases are biofilm-related; however, significant challenges still lie in our ability to diagnose and treat these extremely recalcitrant infections. Written by experts from around the globe, this book offers a valuable resource for medical professionals seeking to treat biofilm-related disease, academic and industry researchers interested in drug discovery and instructors who teach courses on microbial pathogenesis and medical microbiology.
Book Synopsis Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine by : National Academies Of Sciences Engineeri
Download or read book Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine written by National Academies Of Sciences Engineeri and published by National Academies Press. This book was released on 2022-07-20 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Strategy for Combating Antibiotic Resistant Bacteria, published in 2014, sets out a plan for government work to mitigate the emergence and spread of resistant bacteria. Direction on the implementation of this strategy is provided in five-year national action plans, the first covering 2015 to 2020, and the second covering 2020 to 2025. Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine evaluates progress made against the national strategy. This report discusses ways to improve detection of resistant infections and estimate the risk to human health from environmental sources of resistance. In addition, the report considers the effect of agricultural practices on human and animal health and animal welfare and ways these practices could be improved, and advises on key drugs and diseases for which animal-specific test breakpoints are needed.
Book Synopsis Antibiotic Drug Resistance by : José-Luis Capelo-Martínez
Download or read book Antibiotic Drug Resistance written by José-Luis Capelo-Martínez and published by John Wiley & Sons. This book was released on 2019-09-24 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
Book Synopsis Treating Infectious Diseases in a Microbial World by : National Research Council
Download or read book Treating Infectious Diseases in a Microbial World written by National Research Council and published by National Academies Press. This book was released on 2006-01-03 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Book Synopsis Biosurfactants for a Sustainable Future by : Hemen Sarma
Download or read book Biosurfactants for a Sustainable Future written by Hemen Sarma and published by John Wiley & Sons. This book was released on 2021-04-16 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosurfactants for a Sustainable Future Explore the state-of-the-art in biosurfactant technology and its applications in environmental remediation, biomedicine, and biotechnology Biosurfactants for a Sustainable Future explores recent developments in biosurfactants and their use in a variety of cutting-edge applications. The book opens a window on the rapid development of microbiology by explaining how microbes and their products are used in advanced medical technology and in the sustainable remediation of emerging environmental contaminants. The book emphasizes the different techniques that are used for the production of biosurfactants from microorganisms and their characterization. Various aspects of biosurfactants, including structural characteristics, developments, production, bio-economics and their sustainable use in the environment and biomedicine, are addressed, and the book also presents metagenomic strategies to facilitate the discovery of novel biosurfactants producing microorganisms. Readers will benefit from the inclusion of: A thorough introduction to the state-of-the-art in biosurfactant technology, techniques, and applications An exploration of biosurfactant enhanced remediation of sediments contaminated with organics and inorganics A discussion of perspectives for biomedical and biotechnological applications of biosurfactants A review of the antiviral, antimicrobial, and antibiofilm potential of biosurfactants against multi-drug-resistant pathogens. An examination of biosurfactant-inspired control of methicillin-resistant Staphylococcus aureus Perfect for academic researchers and scientists working in the petrochemical industry, pharmaceutical industry, and in the agroindustry, Biosurfactants for a Sustainable Future will also earn a place in the libraries of scientists working in environmental biotechnology, environmental science, and biomedical engineering.
Book Synopsis Technological Challenges in Antibiotic Discovery and Development by : National Research Council
Download or read book Technological Challenges in Antibiotic Discovery and Development written by National Research Council and published by National Academies Press. This book was released on 2014-01-27 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technological Challenges in Antibiotic Discovery and Development is the summary of a workshop convened by the Chemical Sciences Roundtable in September 2013 to explore the current state of antibiotic discovery and examine the technology available to facilitate development. Through formal presentations and panel discussions, participants from academia, industry, federal research agencies discussed the technical challenges present and the incentives and disincentives industry faces in antibiotic development, and identified novel approaches to antibiotic discovery. Antibiotic resistance is a serious and growing problem in modern medicine and it is emerging as a pre-eminent public health threat. Each year in the United States alone, at least two million acquire serious infections with bacteria that are resistant to one or more antibiotics, and at least 23,000 people die annually as a direct result of these antibiotic-resistant infections. In addition to the toll on human life, antibiotic-resistant infections add considerable and avoidable costs to the already overburdened U.S. health care system. This report explores the challenges in overcoming antibiotic resistance, screening for new antibiotics, and delivering them to the sites of infection in the body. The report also discusses a path forward to develop the next generation of potent antimicrobial compounds capable of once again tilting the battle against microbial pathogens in favor of humans. Technological Challenges in Antibiotic Discovery and Development gives a broad view of the landscape of antibiotic development and the technological challenges and barriers to be overcome.
Download or read book Oral Biofilms written by S. Eick and published by Karger Medical and Scientific Publishers. This book was released on 2020-12-21 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms are highly organized polymicrobial communities that are embedded in an extracellular matrix and formed on natural and artificial surfaces. In the oral cavity, biofilms are formed not only on natural teeth, but also on restorative materials, prosthetic constructions, and dental implants. Oral diseases like caries, gingivitis, periodontitis, and also pulp inflammation are associated with biofilms. This publication is an up-to-date overview on oral biofilms from different clinically relevant perspectives. Experts comprising basic researchers and clinicians report on recent research relating to biofilms - from general summaries to recommendations for daily clinical work. This book covers all aspects of oral biofilms, including models used in the laboratory, biofilms in dental water unit lines, periodontal and peri-implant biofilms, caries-related biofilms, halitosis, endodontic biofilms, and Candida infections, as well as biofilms on dental materials and on orthodontic appliances. Several chapters deal with anti-biofilm therapy, from the efficacy of mechanical methods and the use of antimicrobials, to alternative concepts. This publication is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on biofilms.
Book Synopsis The Perfect Slime by : Hans-Curt Flemming
Download or read book The Perfect Slime written by Hans-Curt Flemming and published by IWA Publishing. This book was released on 2016-09-15 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Perfect Slime presents the latest state of knowledge and all aspects of the Extracellular Polymeric Substances, (EPS) matrix – from the ecological and health to the antifouling perspectives. The book brings together all the current material in order to expand our understanding of the functions, properties and characteristics of the matrix as well as the possibilities to strengthen or weaken it. The EPS matrix represents the immediate environment in which biofilm organisms live. From their point of view, this matrix has paramount advantages. It allows them to stay together for extended periods and form synergistic microconsortia, it retains extracellular enzymes and turns the matrix into an external digestion system and it is a universal recycling yard, it protects them against desiccation, it allows for intense communication and represents a huge genetic archive. They can remodel their matrix, break free and eventually, they can use it as a nutrient source. The EPS matrix can be considered as one of the emergent properties of biofilms and are a major reason for the success of this form of life. Nevertheless, they have been termed the “black matter of biofilms” for good reasons. First of all: the isolation methods define the results. In most cases, only water soluble EPS components are investigated; insoluble ones such as cellulose or amyloids are much less included. In particular in environmental biofilms with many species, it is difficult to impossible isolate, separate the various EPS molecules they are encased in and to define which species produced which EPS. The regulation and the factors which trigger or inhibit EPS production are still very poorly understood. Furthermore: bacteria are not the only microorganisms to produce EPS. Archaea, Fungi and algae can also form EPS. This book investigates the questions, What is their composition, function, dynamics and regulation? What do they all have in common?
Book Synopsis Antibiotics and Antimicrobial Resistance Genes by : Muhammad Zaffar Hashmi
Download or read book Antibiotics and Antimicrobial Resistance Genes written by Muhammad Zaffar Hashmi and published by Springer Nature. This book was released on 2020-04-07 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes and updates information about antibiotics and antimicrobial resistance (AMR)/antibiotic resistant genes (ARG) production, including their entry routes in soil, air, water and sediment, their use in hospital and associated waste, global and temporal trends in use and spread of antibiotics, AMR and ARG. Antimicrobial/antibiotic resistance genes due to manure and agricultural waste applications, bioavailability, biomonitoring, and their Epidemiological, ecological and public health effects. The book addresses the antibiotic and AMR/ARG risk assessment and treatment technologies, for managing antibiotics and AMR/ARG impacted environments The book's expert contributions span 20 chapters, and offer a comprehensive framework for better understanding and analyzing the environmental and social impacts of antibiotics and AMR/ARGs. Readers will have access to recent and updated models regarding the interpretation of antibiotics and AMR/ARGs in environment and biomonitoring studies, and will learn about the management options require to appropriately mitigate environmental contaminants and pollution. The book will be of interest to students, teachers, researchers, policy makers and environmental organizations.
Book Synopsis Microbial Evolution and Co-Adaptation by : Institute of Medicine
Download or read book Microbial Evolution and Co-Adaptation written by Institute of Medicine and published by National Academies Press. This book was released on 2009-05-10 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Joshua Lederberg - scientist, Nobel laureate, visionary thinker, and friend of the Forum on Microbial Threats - died on February 2, 2008. It was in his honor that the Institute of Medicine's Forum on Microbial Threats convened a public workshop on May 20-21, 2008, to examine Dr. Lederberg's scientific and policy contributions to the marketplace of ideas in the life sciences, medicine, and public policy. The resulting workshop summary, Microbial Evolution and Co-Adaptation, demonstrates the extent to which conceptual and technological developments have, within a few short years, advanced our collective understanding of the microbiome, microbial genetics, microbial communities, and microbe-host-environment interactions.
Book Synopsis Bacterial Persistence by : Jan Michiels
Download or read book Bacterial Persistence written by Jan Michiels and published by Humana. This book was released on 2015-10-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a comprehensive collection of methods that have been instrumental to the current understanding of bacterial persisters. Chapters in the book cover topics ranging from general methods for measuring persister levels in Escherichia coli cultures, protocols for the determination of the persister subpopulation in Candida albicans, quantitative measurements of Type I and Type II persisters using ScanLag, to in vitro and in vivo models for the study of the intracellular activity of antibiotics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Bacterial Persistence: Methods and Protocols brings together the most respected researchers in bacterial persistence whose studies will remain vital to understanding this field for many years to come.
