Autophagy And Cardiometabolic Diseases

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Autophagy and Cardiometabolic Diseases

Author : Jun Ren
Publisher : Academic Press
ISBN 13 : 0128054425
Total Pages : 340 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Autophagy and Cardiometabolic Diseases by : Jun Ren

Download or read book Autophagy and Cardiometabolic Diseases written by Jun Ren and published by Academic Press. This book was released on 2018-04-12 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy and Cardiometabolic Diseases: From Moleculer Mechanisms to Translational Medicine covers the science of autophagy in relation to cardiometabolic diseases and the future therapeutic potentials of autophagy regulation in these processes. Processes are not described in isolation, but in concert with other cellular and/or metabolic processes, such as lipogenesis, glucose, energy metabolism and apoptosis. This approach recognizes the multifactorial nature of cardiometabolic diseases, including obesity, diabetes, insulin resistance, hypertension and dyslipidemia. The book provides explanations, while also distinguishing the delicate role for autophagy in pathogenesis and exploring complications for cardiometabolic diseases. By targeting autophagy, it offers new avenues for drug discovery and treatment for cardiometabolic anomalies. It is a perfect resource for cardiology researchers, scientists and medical practitioners. Explains the processes inherent in the protein quality control for pathogenesis and complications of cardiometabolic diseases Provides knowledge from internationally recognized contributors in the field Incorporates a translational approach, covering the basic cellular biology of autophagy and presenting the role of autophagy regulation for both pathogenesis and complication in cardiometabolic diseases Contains access to a companion website with additional illustrations

Autophagy in Endocrine-metabolic Diseases Associated with Aging

Author : Maria Ines Vaccaro
Publisher : Frontiers Media SA
ISBN 13 : 2889660796
Total Pages : 142 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Autophagy in Endocrine-metabolic Diseases Associated with Aging by : Maria Ines Vaccaro

Download or read book Autophagy in Endocrine-metabolic Diseases Associated with Aging written by Maria Ines Vaccaro and published by Frontiers Media SA. This book was released on 2020-12-11 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Autophagy in Health and Disease

Author : Beverly Rothermel
Publisher : Elsevier
ISBN 13 : 012822004X
Total Pages : 456 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Autophagy in Health and Disease by : Beverly Rothermel

Download or read book Autophagy in Health and Disease written by Beverly Rothermel and published by Elsevier. This book was released on 2021-09-22 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy in Health and Disease, Second Edition provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysiology. It expands on the scope of the first edition by covering a wider range of cell types, developmental processes, and organ systems. The second edition is an international effort by investigators from 15 different countries whose many contributions are comprised in 28 chapters organized into six sections. The first section (Chapters 1-7) covers foundational concepts, including history, trajectory of the research field, mechanisms of autophagy, and autophagy regulation. The second section (Chapters 8-11) details developmental aspects, including stem cells, embryogenesis, hematopoiesis, and paligenosis. The subsequent sections are devoted to the role of autophagy in specific organ systems involved in metabolic control and diabetes (Chapters 12-15), the cardiovascular system (Chapters 16-18), and the nervous system (Chapters 19-20). The final section (Chapters 21-28) addresses autophagy in other organ systems vital to human health and longevity. Also included are chapters on microautophagy, chaperone-mediated autophagy, and the potential for autophagy as a therapeutic target. Autophagy in Health and Disease is invaluable to anyone new to the field as well as established investigators looking for a broader understanding of autophagy from outside their specific field of study. Provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathology Offers extended coverage of the mechanisms that mediate autophagy Covers the role of autophagy in stem cells and induced pluripotent stem cells, as well as the regenerative process of paligenosis Highlights important questions that remain to be addressed

Interplay between Autophagy and Metabolic Syndrome: Causes, Consequences and Therapeutic Challenges

Author : Joilson O. Martins
Publisher : Frontiers Media SA
ISBN 13 : 288971747X
Total Pages : 224 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Interplay between Autophagy and Metabolic Syndrome: Causes, Consequences and Therapeutic Challenges by : Joilson O. Martins

Download or read book Interplay between Autophagy and Metabolic Syndrome: Causes, Consequences and Therapeutic Challenges written by Joilson O. Martins and published by Frontiers Media SA. This book was released on 2021-12-01 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Exercise, Autophagy and Chronic Diseases

Author : Ning Chen
Publisher : Springer Nature
ISBN 13 : 9811645256
Total Pages : 267 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Exercise, Autophagy and Chronic Diseases by : Ning Chen

Download or read book Exercise, Autophagy and Chronic Diseases written by Ning Chen and published by Springer Nature. This book was released on 2021-09-30 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book establishes a bridge between exercise-mediated functional status of autophagy and non-communicable chronic diseases for elucidating and clarifying the corresponding signal pathways and underlying mechanisms. The book consists of 13 chapters focusing on the in-depth discussion on signal pathways for regulating the functional status of autophagy for the prevention, treatment and rehabilitation of chronic diseases, the optimization of exercise intervention strategies for common and frequently-occurring chronic diseases, and the development of exercise mimetic pills for the persons with disability for exercise performance, or the persons without willing to exercise. This book is interesting and will be useful to a wide readership in the various fields of exercise science, exercise fitness, sports medicine, preventive medicine, and functional foods.

Autophagy: Biology and Diseases

Author : Weidong Le
Publisher : Springer Nature
ISBN 13 : 9811542724
Total Pages : 734 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Autophagy: Biology and Diseases by : Weidong Le

Download or read book Autophagy: Biology and Diseases written by Weidong Le and published by Springer Nature. This book was released on 2020-07-15 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book consists of 3 volumes: Basic Science (Volume 1), Clinical Science (Volume 2) and Technology and Methodology (Volume 3). Volume 2 focuses on the clinical aspects of autophagy research, discussing the role of autophagy in neuropsychiatric disorders, the cardiovascular, immune, digestive and endocrine systems, as well as tumors, infection, the kidney, and the respiratory and hematological systems. It also addresses autophagy-related drug development. Written and edited by a team of 90 experts, and presenting the state of the art in autophagy research, this book is a valuable reference resource for researchers and clinicians alike. It can also be used as supplementary material for graduate students majoring in biology and medicine

Metabolic Cardiomyopathy

Author : H. Böhles
Publisher : CRC Press
ISBN 13 : 9783887631048
Total Pages : 188 pages
Book Rating : 4.6/5 (31 download)

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Book Synopsis Metabolic Cardiomyopathy by : H. Böhles

Download or read book Metabolic Cardiomyopathy written by H. Böhles and published by CRC Press. This book was released on 2004 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.

Autophagy and Metabolic Syndrome: From Molecular Mechanisms to Clinical Consequences

Author : Esther Bennett
Publisher : Hayle Medical
ISBN 13 : 9781646475599
Total Pages : 0 pages
Book Rating : 4.4/5 (755 download)

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Book Synopsis Autophagy and Metabolic Syndrome: From Molecular Mechanisms to Clinical Consequences by : Esther Bennett

Download or read book Autophagy and Metabolic Syndrome: From Molecular Mechanisms to Clinical Consequences written by Esther Bennett and published by Hayle Medical. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy is a process in which cells capture their own cytoplasm and organelles and consume them in lysosomes. This mechanism preserves the health of cells and tissues through the replacement of damaged and outdated cellular components with new ones. The breakdown products serve as inputs to cellular metabolism. Autophagy prevents degenerative diseases as it is a powerful promoter of metabolic homeostasis at both the cellular and whole animal level. It reduces ubiquitinated protein accumulation in the brain, and disposes-off the aggregation-prone proteins and damaged organelles that cause Huntington's disease and Parkinson's disease. The metabolic syndrome refers to a group of medical conditions which increase the likelihood of heart disease, diabetes and stroke. It encompasses high blood sugar, hypertension, high cholesterol levels and excess fat around the waist. The process of autophagy has an effect on the development of metabolic syndrome since the metabolic syndrome is caused due to the accumulation of damaged cellular constituents. This book includes some of the vital pieces of works being conducted across the world, on various topics related to autophagy and metabolic syndrome. It is appropriate for students seeking detailed information in this area of medicine as well as for experts.

Autophagy in Health and Disease

Author : Roberta A. Gottlieb
Publisher : Academic Press
ISBN 13 : 0123851025
Total Pages : 240 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Autophagy in Health and Disease by : Roberta A. Gottlieb

Download or read book Autophagy in Health and Disease written by Roberta A. Gottlieb and published by Academic Press. This book was released on 2012-12-31 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy in Health and Disease offers an overview of the latest research in autophagy with a translational emphasis. This publication takes scientific research in autophagy a step further and offers integrated content with advancements in autophagy from cell biology and biochemical research to clinical treatments. A necessary reference for the bookshelf of medical and scientific researchers and students, Autophagy in Health and Disease presents high quality, reputable information on autophagy, allowing the reader quick access to the most applicable information. Discusses current understanding of the roles of autophagy in health and disease Covers the background of autophagy, the development of tools and therapeutics to measure and modulate autophagy, and autophagy in tissues and disease processes Features an accompanying website with figures and tables

Oxidative Stress in Heart Diseases

Author : Sajal Chakraborti
Publisher : Springer Nature
ISBN 13 : 9811382735
Total Pages : 596 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Oxidative Stress in Heart Diseases by : Sajal Chakraborti

Download or read book Oxidative Stress in Heart Diseases written by Sajal Chakraborti and published by Springer Nature. This book was released on 2019-11-06 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.

Biochemistry of Apoptosis and Autophagy

Author : Lorrie A. Kirshenbaum
Publisher : Springer
ISBN 13 : 9783030788018
Total Pages : 0 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Biochemistry of Apoptosis and Autophagy by : Lorrie A. Kirshenbaum

Download or read book Biochemistry of Apoptosis and Autophagy written by Lorrie A. Kirshenbaum and published by Springer. This book was released on 2022-11-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most intriguing and compelling issues to impact contemporary biology to date is the concept that cell death is genetically regulated. Observations by Kerr and Wyllie, made more than 30 years ago on the basis of distinct morphological criteria, markedly distinguished apoptosis from classical cell death by necrosis. Apoptosis is a highly regulated, evolutionary conserved, genetic program of cell death essential for normal development and tissue homeostasis. The discovery of apoptosis as a regulated event and potentially amenable to therapeutic interventions has generated considerable excitement because it meant that disease entities resulting from either too much, or too little, apoptosis could be potentially cured with new therapies that target apoptosis. While there is little doubt that necrosis induced by massive cellular trauma is likely an unregulated event, several lines of investigation have challenged the dogma that necrotic cell death is merely unregulated. Emerging data has shifted the paradigm in our thinking about necrosis as a regulated event. Autophagy is another cellular process that has received considerable attention over the past two decades and its remarkable involvement in the processes of cell survival, death and tumorigenesis. Macro autophagy is a catabolic process that involves the selective and targeted removal of oxidized proteins, macromolecular structures and organelles through an elaborate cellular process involving a lysosome mediated pathway. Other forms of autophagy involving adapter proteins, commonly referred to as chaperone mediated autophagy, involves the selective removal of cellular cargo by the ubiquitin-proteasome pathway. The book will serve as a reference guide for basic and clinical scientists who are interested in understanding how these critical cellular processes impact the pathogenesis of human disease.

Cardiovascular Risk Factors in Pathology

Author : Alaeddin Abukabda
Publisher : BoD – Books on Demand
ISBN 13 : 1838819495
Total Pages : 144 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Cardiovascular Risk Factors in Pathology by : Alaeddin Abukabda

Download or read book Cardiovascular Risk Factors in Pathology written by Alaeddin Abukabda and published by BoD – Books on Demand. This book was released on 2021-04-21 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad overview of the molecular mechanisms associated with relevant and significant cardiovascular conditions that continue to plague humanity. It also discusses potential and promising therapeutic avenues targeted at addressing these conditions. The overarching goal of this multifaceted work is to entice future and current members of the scientific community to direct their endeavors towards improving our current knowledge of cardiovascular disease conditions and curb their impact on our everyday lives.

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

Author : M. A. Hayat
Publisher : Academic Press
ISBN 13 : 0128094273
Total Pages : 430 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging by : M. A. Hayat

Download or read book Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging written by M. A. Hayat and published by Academic Press. This book was released on 2016-12-28 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is an eleven volume series that discusses in detail all aspects of autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. This series discusses the characterization of autophagosome-enriched vaccines and its efficacy in cancer immunotherapy. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward-thinking, these books offer a valuable guide to cellular processes while also inciting researchers to explore their potentially important connections. Presents the most advanced information regarding the role of the autophagic system in life and death Examines whether autophagy acts fundamentally as a cell survivor or cell death pathway or both Introduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation Features recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, including atherosclerosis and CNS tumors, and their development and treatment Includes chapters authored by leaders in the field around the globe—the broadest, most expert coverage available

Autophagy and Senescence in Cancer Therapy

Author :
Publisher : Academic Press
ISBN 13 : 0128241594
Total Pages : 384 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Autophagy and Senescence in Cancer Therapy by :

Download or read book Autophagy and Senescence in Cancer Therapy written by and published by Academic Press. This book was released on 2021-04-13 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cancer Research, Volume 150, the latest release in this ongoing series, covers the relationship(s) between autophagy and senescence, how they are defined, and the influence of these cellular responses on tumor dormancy and disease recurrence. Specific sections in this new release include Autophagy and senescence, converging roles in pathophysiology, Cellular senescence and tumor promotion: role of the unfolded protein response, autophagy and senescence in cancer stem cells, Targeting the stress support network regulated by autophagy and senescence for cancer treatment, Autophagy and PTEN in DNA damage-induced senescence, mTOR as a senescence manipulation target: A forked road, and more. Addresses the relationship between autophagy and senescence in cancer therapy Covers autophagy and senescence in tumor dormancy Explores autophagy and senescence in disease recurrence

Functional Foods for Chronic Diseases (Volume 3)

Author : Danik M. Martirosyan
Publisher : D&A Inc.
ISBN 13 : 9780976753544
Total Pages : 280 pages
Book Rating : 4.7/5 (535 download)

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Book Synopsis Functional Foods for Chronic Diseases (Volume 3) by : Danik M. Martirosyan

Download or read book Functional Foods for Chronic Diseases (Volume 3) written by Danik M. Martirosyan and published by D&A Inc.. This book was released on 2008-02-10 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of this book serves two great purposes. First, it spreads the word about new functional food products for chronic diseases such as hypertension, diabetes, and obesity to the general public. It not only introduces new functional foods, but also shows the investigations and research that led to their creation. Second, the book preserves the numerous ideas and contributions made in the field. This shows the progress and evolution of this thriving field, with the power to change the lives of millions of people. The forever growing field of functional foods brings together research scientists, food manufacturers and consumers who are committed to this issue through modern achievements of surgical approaches and potential of drug therapy, where particular emphasis is placed on the unresolved problems of pharmaceutical side effects.

Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease

Author : Thomas Pulinilkunnil
Publisher : Frontiers Media SA
ISBN 13 : 2889459381
Total Pages : 89 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease by : Thomas Pulinilkunnil

Download or read book Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease written by Thomas Pulinilkunnil and published by Frontiers Media SA. This book was released on 2019-08-08 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

The Heterogeneity of Cancer Metabolism

Author : Anne Le
Publisher : Springer
ISBN 13 : 331977736X
Total Pages : 186 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le

Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.