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Autism Spectrum Disorders Asd Searching For The Biological Basis For Behavioral Symptoms And New Therapeutic Targets
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Book Synopsis Autism Spectrum Disorders (ASD) - Searching for the Biological Basis for Behavioral Symptoms and New Therapeutic Targets by : Benjamin Gesundheit
Download or read book Autism Spectrum Disorders (ASD) - Searching for the Biological Basis for Behavioral Symptoms and New Therapeutic Targets written by Benjamin Gesundheit and published by Frontiers Media SA. This book was released on 2017-03-07 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autism Spectrum Disorder (ASD) is currently diagnosed based on a series of behavioral tests. The challenge for researchers is to try to uncover the biological basis for these typical behaviors in order to improve diagnosis and identify potential targets for treatment. A multidisciplinary approach is necessary in order to move forward. This includes analysis of the current animal models for ASD and their suitability, reviewing immunological, immunogenetic and epigenetic research, reassessing clinical diagnostic tools, and surveying radiological, pathological, and serological records for clues. This volume includes research from some of the leading researchers on ASD. We are hopeful that it will stimulate further dialogue and research in this challenging field.
Book Synopsis Autism Spectrum Disorders (ASD) - Searching for the Biological Basis for Behavioral Symptoms and New Therapeutic Targets by :
Download or read book Autism Spectrum Disorders (ASD) - Searching for the Biological Basis for Behavioral Symptoms and New Therapeutic Targets written by and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autism Spectrum Disorder (ASD) is currently diagnosed based on a series of behavioral tests. The challenge for researchers is to try to uncover the biological basis for these typical behaviors in order to improve diagnosis and identify potential targets for treatment. A multidisciplinary approach is necessary in order to move forward. This includes analysis of the current animal models for ASD and their suitability, reviewing immunological, immunogenetic and epigenetic research, reassessing clinical diagnostic tools, and surveying radiological, pathological, and serological records for clues. This volume includes research from some of the leading researchers on ASD. We are hopeful that it will stimulate further dialogue and research in this challenging field.
Book Synopsis Autism Spectrum Disorder within Neurodevelopmental Disorders: Catching Heterogeneity, Specificity and Comorbidity in Clinical Phenotypes and Neurobiological Bases by : Eugenia Conti
Download or read book Autism Spectrum Disorder within Neurodevelopmental Disorders: Catching Heterogeneity, Specificity and Comorbidity in Clinical Phenotypes and Neurobiological Bases written by Eugenia Conti and published by Frontiers Media SA. This book was released on 2022-09-14 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fast Facts for Managing Patients with a Psychiatric Disorder by : Brenda Marshall, EdD, PMHNP-BC, ANEF
Download or read book Fast Facts for Managing Patients with a Psychiatric Disorder written by Brenda Marshall, EdD, PMHNP-BC, ANEF and published by Springer Publishing Company. This book was released on 2017-08-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to address the care of dual-diagnosis patients in non-psychiatric settings Brimming with practical insights and strategies, this unique Fast Facts resource delivers concise, quick-access information about caring for patients with common physical complaints who also have a psychiatric diagnosis. It is the first book written for non-psychiatric nurses in multiple clinical settings to address the needs of patients with co-morbid diagnoses, and facilitates the integration of skills and strategies that support recovery for patients diagnosed with mental illness. Delivered in a convenient pocket-sized format, the guide delivers comprehensive information in easy-to-access short chapters, bulleted lists, tables, and figures, along with “Fast Facts in a Nutshell” boxes featuring key information. It covers the diagnoses of common psychiatric disorders and addresses the symptom alliance between various medical diagnoses and mental illness, and substance abuse and co-occurring mental disorders. Also included are strategies for establishing a therapeutic alliance with patients with psychiatric disorders and issues posing challenges for nurses in specific clinical settings. Additionally, the book explores the legal and ethical issues surrounding provision of care to patients with mental illness. Key Features: Delivers quick-access information about caring for patients with co-morbid diagnoses—the first book to do so Written for non-psychiatric nurses in a variety of clinical settings Presents key information in short chapters, bulleted content, lists, tables, and figures plus “Fast Facts” boxes Covers the diagnoses of common psychiatric disorders and de-stigmatizes patients with mental illness Provides strategies for fostering successful nursing interventions
Book Synopsis Autism Spectrum Disorders: Developmental Trajectories, Neurobiological Basis, Treatment Update by : Roberto Canitano
Download or read book Autism Spectrum Disorders: Developmental Trajectories, Neurobiological Basis, Treatment Update written by Roberto Canitano and published by Frontiers Media SA. This book was released on 2017-08-30 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Research Topic has the aim to fill the gap of the many unresolved scientific issues on Autism Spectrum Disorders (ASD) that are still in need of investigation, Targeted treatments based on the understanding of the underlying pathogenic mechanisms of disease are still lacking. Further research is awaited and should be obtained through a significant effort on experimental treatment trials and neuroscience research. This Topic is divided in two main sections, one covering clinical issues and another on basic neurosciences of Autism Spectrum Disorders. A more detailed description of the contents of the articles is provided in the editorial at the beginning of the issue.
Book Synopsis New treatment perspectives in autism spectrum disorders by : Roberto Canitano
Download or read book New treatment perspectives in autism spectrum disorders written by Roberto Canitano and published by Frontiers Media SA. This book was released on 2015-04-17 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developing novel and more effective treatments that improve quality of life for individuals with autism spectrum disorders is urgently needed. To date a wide range of behavioral interventions have been shown to be safe and effective for improving language and cognition and adaptive behavior in children and adolescents with ASD. However many people with ASD can receive additional benefit from targeted pharmacological interventions. One of the major drawback in setting up therapeutics intervention is the remarkable individual differences found across individuals with ASD. As a matter of fact the medications that are currently available address only symptoms associated with ASD and not the core domains of social and communication dysfunction. The pathogenesis paradigm shift of ASD towards synaptic abnormalities moved the research to pathway to disease that involve multiple systems and that are becoming the forefront of ASD treatment and are pointing toward the development of new targeted treatments. Some new therapeutics have been tested and others are being studied. In this context single gene disorders frequently associated with ASD such as Rett Syndrome, Fragile X and Tuberous Sclerosis have been of significant aid as neurobiology of these disorders is more clear and has a potential to shed light on the altered signaling in ASD. However much research is needed to further understand the basic mechanisms of disease and the relationship to idiopathic ASD. Clinical trials in children are underway with agents directed to core symptoms and to the associated disorders in the search of new therapeutics and progress are expected with possible new option for therapeutics in ASD in the upcoming future. Children and Adolescents with ASD and their families can provide important information about their experience with new treatments and this should be a priority for future research. In addition, research performed on genetic mouse models of ASD will keep on providing useful information on the molecular pathways dysrupted in the disease, thus contributing to identify novel drug targets.
Book Synopsis Repetitive and Restricted Behaviors and Interests in Autism Spectrum Disorders by : Eynat Gal
Download or read book Repetitive and Restricted Behaviors and Interests in Autism Spectrum Disorders written by Eynat Gal and published by Springer Nature. This book was released on 2021-04-05 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines repetitive and restrictive behaviors and interests (RRBIs) affecting individuals with autism spectrum disorder (ASD). The various aspects of RRBIs, an umbrella term for a broad class of behaviors linked by repetition, rigidity, invariance, and inappropriateness to place and context are reviewed by an international team of expert leaders in the field. Key topics of coverage include: Neurological Mechanisms Underlying Repetitive: Animal and human models Underlying mechanisms of RRBs across typical and atypical development The relationship between RRBI and other characteristics of ASD (communication, social, sensory aspects) RRBIs and adults with ASD Diagnosing RRBIs An RRBI intervention model The book bridges the gap between the neurobiological and neurocognitive bodies of knowledge in relation to RRBIs and their behavioral aspects and examines associations with other domains of ASD. In addition, the volume addresses related assessment and treatment of RRBI in ASD. This is an essential resource for researchers, graduate students, clinicians and related therapists and professionals in developmental psychology, behavioral therapy/rehabilitation, social work, clinical child and school psychology, child and adolescent psychiatry, pediatrics, occupational therapy and special education.
Book Synopsis Autism Service Delivery by : Florence D. DiGennaro Reed
Download or read book Autism Service Delivery written by Florence D. DiGennaro Reed and published by Springer. This book was released on 2015-09-09 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume examines ways in which service delivery to individuals with autism can be improved from both ends of the basic-applied research spectrum. It introduces the concept of translational scholarship and examines real-world value in developing relevant interventions. Each area of coverage reviews current findings on autism from basic research and, then, discusses the latest applied research literature to create a roadmap for researchers, clinicians, and scientist-practitioners to develop new, effective strategies as children, adolescents, and adults with autism continue to learn and grow. Featured coverage includes: Why practice needs science and how science informs practice. The social learning disorder of stimulus salience in autism. Assessment and treatment of problem behaviors associated with transitions. Understanding persistence and improving treatment through behavioral momentum theory. The behavioral economics of reinforcer value. Increasing tolerance for delay with children and adults with autism. Autism Service Delivery is an essential resource for researchers, clinicians and scientist-practitioners, and graduate students in the fields of developmental psychology, behavioral therapy, social work, clinical child and school psychology, occupational therapy, and speech pathology.
Book Synopsis Textbook of Autism Spectrum Disorders, Second Edition by : Eric Hollander, M.D.
Download or read book Textbook of Autism Spectrum Disorders, Second Edition written by Eric Hollander, M.D. and published by American Psychiatric Pub. This book was released on 2022-03-15 with total page 744 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 40 years after the official recognition of infantile autism in DSM-III, advances continue to be made in our understanding of the possible causes, assessment and evaluation, and treatment of autism spectrum disorder (ASD). With contributions by dozens of experts in the field, this second edition of the Textbook of Autism Spectrum Disorders has been updated to reflect the latest research in ASD. Unrivaled in its thoroughness, this volume discusses issues of assessment and evaluation; examines the etiology of ASD and its recognized associations with other medical conditions; analyzes standard and experimental treatments; and delves into social policy issues pertinent to individuals with ASD and those who treat them. With summary points in each chapter and copious lists of recommended readings, this is an indispensable resource for psychiatrists, psychologists, neurologists, social workers, speech therapists, educators, and all others in the continuum of care.
Book Synopsis Effective Programs for Treating Autism Spectrum Disorder by : Betty Fry Williams
Download or read book Effective Programs for Treating Autism Spectrum Disorder written by Betty Fry Williams and published by Routledge. This book was released on 2010-09-15 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Effective Programs for Treating Autism Spectrum Disorder is written for teachers, parents, and the many service providers who work with individuals with autism spectrum disorder (ASD). Part one reviews the characteristics of ASD, summarizes major theories and research findings regarding cause(s) of ASD, and discusses the most popular treatment claims, examining each approach's scientific base and value. Part two provides an informative overview of applied behavior analysis, focusing on the principles of learning and basic procedures based upon those principles. These two parts provide a foundation for understanding the strategies implemented by the outstanding treatment programs described in Part three. The eight models described in Part three represent comprehensive, evidence-based programs for the treatment of persons with ASD, from infancy through adulthood. Programs reviewed include the Lovaas Institute, Koegel Center, Strategic Teaching and Reinforcement Systems (STARS), Project DATA, New England Children's Center, May Institute, Princeton Child Development Institute, and Judge Rotenberg Center. Strategies explained include intensive early behavioral intervention, Pivotal Response Training, verbal behavior, script fading, social stories, visual activity schedules, functional analysis, the Picture Exchange Communication System, and the Family-Teaching Model.
Book Synopsis Homeostatic Control of Brain Function by : Detlev Boison
Download or read book Homeostatic Control of Brain Function written by Detlev Boison and published by Oxford University Press. This book was released on 2016 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homeostatic Control of Brain Function offers a broad view of brain health and diverse perspectives for potential treatments, targeting key areas such as mitochondria, the immune system, epigenetic changes, and regulatory molecules such as ions, neuropeptides, and neuromodulators. Loss of homeostasis becomes expressed as a diverse array of neurological disorders. Each disorder has multiple comorbidities - with some crossing over several conditions - and often disease-specific treatments remain elusive. When current pharmacological therapies result in ineffective and inadequate outcomes, therapies to restore and maintain homeostatic functions can help improve brain health, no matter the diagnosis. Employing homeostatic therapies may lead to future cures or treatments that address multiple comorbidities. In an age where brain diseases such as Alzheimer's or Parkinson's are ever present, the incorporation of homeostatic techniques could successfully promote better overall brain health. Key Features include · A focus on the homeostatic controls that significantly depend on the way one lives, eats, and drinks. · Highlights from emerging research in non-pharmaceutical therapies including botanical medications, meditation, diet, and exercise. · Incorporation of homeostatic therapies into existing basic and clinical research paradigms. · Extensive scientific basic and clinical research ranging from molecules to disorders. · Emerging practical information for improving homeostasis. · Examples of homeostatic therapies in preventing and delaying dysfunction. Both editors, Detlev Boison and Susan Masino, bring their unique expertise in homeostatic research to the overall scope of this work. This book is accessible to all with an interest in brain health; scientist, clinician, student, and lay reader alike.
Book Synopsis Autism Spectrum Disorders by : Andreas M. Grabrucker
Download or read book Autism Spectrum Disorders written by Andreas M. Grabrucker and published by . This book was released on 2021 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.
Book Synopsis Psychiatric Symptoms and Comorbidities in Autism Spectrum Disorder by : Luigi Mazzone
Download or read book Psychiatric Symptoms and Comorbidities in Autism Spectrum Disorder written by Luigi Mazzone and published by Springer. This book was released on 2016-05-19 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains in detail the diagnosis, management, and treatment of comorbid disorders in patients with autism spectrum disorders (ASD). Important insights are provided into the nature of the symptoms of psychiatric comorbidities in these patients, and particularly children and adolescents, with a view to assisting clinicians in reaching a correct diagnosis that will permit the implementation of appropriate treatment strategies, whether psychological or pharmacological. The full range of potential comorbidities is considered, including mood disorders, anxiety disorders, obsessive-compulsive disorder, schizophrenia spectrum and other psychotic disorders, eating disorders, disruptive behavioral disorders, Tourette’s disorder, and substance-related disorders. In each case guidance is provided on how to avoid incorrectly attributing symptoms to ASD and on treatment options. Psychiatric Comorbidities in Autism Spectrum Disorders will be of value to all practitioners who are confronted by patients with these complex co-occurring conditions.
Download or read book Autism written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2005-01-21 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book draws together contributions from some of the leading investigators in the field of autism to consider specific problem areas in current research. Each contributor brings expertise from a different field, providing a balanced view of the whole spectrum of study of this disorder. It covers four main areas: Twin and family studies indicate that the heritability of the underlying liability to autism exceeds 90% and point to a multifactorial causation, involving a relatively small number of susceptibility genes. The book discusses this issue in detail, along with the problem of why some additional symptoms are associated with autism while others are not. New techniques are available for examining the neurobiology of autism. The book contains results from imaging studies showing the contributions of different brain regions to autism. It includes neuropathological data and examines the neuropharmacology of autism. There is considerable discussion concerning the fundamental psychological deficit in children with autism. There is good evidence that "Theory of Mind" deficits are associated with autism and this issue is discussed in the book, as are other competing possibilities. The most important practical question facing medical and psychological practitioners is how to help children with autism. The evidence relating to possible psychological or psychiatric interventions for rehabilitation of children with autism is examined in detail. Drug treatments have generally been disappointing in this field and there is one chapter devoted specifically to this problem. The book focusses ultimately on intervention studies and so is of practical relevance to people interested in helping autistic children. In addition, it provides a very convenient summary of the principal controversies which currently exist in research on autism.
Book Synopsis Neural and Synaptic Defects in Autism Spectrum Disorders by : Hansen Wang
Download or read book Neural and Synaptic Defects in Autism Spectrum Disorders written by Hansen Wang and published by Frontiers Media SA. This book was released on 2015-07-07 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autism spectrum disorders (ASDs) are a group of genetically and clinically heterogeneous neurodevelopmental disorders characterized by impaired reciprocal social interactions and communication, and restricted and repetitive patterns of behaviors and interests. Studies in genetics, neurobiology and systems biology are providing insights into the pathogenesis of ASDs. Investigation of neural and synaptic defects in ASDs not only sheds light on the molecular and cellular mechanisms that govern the function of the central nervous system, but may lead to the discovery of potential therapeutic targets for autism and other cognitive disorders. Our Research Topic which constitutes this e-book documents the recent development and ideas in the study of pathogenesis and treatment of ASDs, with an emphasis on syndromic disorders such as fragile X and Rett syndromes. In addition, model systems and methodological approaches with translational relevance to autism are covered herein. We hope that the Research Topic will enhance the global knowledge base in the autism research community and foster new research directions in autism related biology.
Book Synopsis The Neuroscience of Autism Spectrum Disorders by : Joseph D. Buxbaum
Download or read book The Neuroscience of Autism Spectrum Disorders written by Joseph D. Buxbaum and published by Academic Press. This book was released on 2012-12-31 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise. Uniquely explores ASDs from a neurobiological angle, looking to uncover the molecular/cellular basis rather than to merely catalog the commonly used behavioral interventions Comprehensive coverage synthesizes widely dispersed research, serving as one-stop shopping for neurodevelopmental disorder researchers and autism specialists Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available
Book Synopsis Child and Adolescent Behavioral Health by : Edilma L. Yearwood
Download or read book Child and Adolescent Behavioral Health written by Edilma L. Yearwood and published by John Wiley & Sons. This book was released on 2021-02-23 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research has shown that a range of adult psychiatric disorders and mental health problems originate at an early age, yet the psychiatric symptoms of an increasing number of children and adolescents are going unrecognized and untreated—there are simply not enough child psychiatric providers to meet this steadily rising demand. It is vital that advanced practice registered nurses (APRNs) and primary care practitioners take active roles in assessing behavioral health presentations and work collaboratively with families and other healthcare professionals to ensure that all children and adolescents receive appropriate treatment. Child and Adolescent Behavioral Health helps APRNs address the mental health needs of this vulnerable population, providing practical guidance on assessment guidelines, intervention and treatment strategies, indications for consultation, collaboration, referral, and more. Now in its second edition, this comprehensive and timely resource has been fully updated to include DSM-5 criteria and the latest guidance on assessing, diagnosing, and treating the most common behavioral health issues facing young people. New and expanded chapters cover topics including eating disorders, bullying and victimization, LGBTQ identity issues, and conducting research with high-risk children and adolescents. Edited and written by a team of accomplished child psychiatric and primary care practitioners, this authoritative volume: Provides state-of-the-art knowledge about specific psychiatric and behavioral health issues in multiple care settings Reviews the clinical manifestation and etiology of behavioral disorders, risk and management issues, and implications for practice, research, and education Offers approaches for interviewing children and adolescents, and strategies for integrating physical and psychiatric screening Discusses special topics such as legal and ethical issues, cultural influences, the needs of immigrant children, and child and adolescent mental health policy Features a new companion website containing clinical case studies to apply concepts from the chapters Designed to specifically address the issues faced by APRNs, Child and Adolescent Behavioral Health is essential reading for nurse practitioners and clinical nurse specialists, particularly those working in family, pediatric, community health, psychiatric, and mental health settings.
