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Applied Pharmacokinetics
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Book Synopsis Applied Clinical Pharmacokinetics by : Larry A. Bauer
Download or read book Applied Clinical Pharmacokinetics written by Larry A. Bauer and published by McGraw Hill Professional. This book was released on 2007-09-22 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: New sections on dosing strategies in all chapters. New chapter on sirolimus under the Immunosuppressants section. Essential information on drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure. 30% of chapters extensively revised, others lightly updated
Book Synopsis Applied Pharmacokinetics & Pharmacodynamics by : Michael E. Burton
Download or read book Applied Pharmacokinetics & Pharmacodynamics written by Michael E. Burton and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 924 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive advanced-level clinical pharmacokinetics text is now in its Fourth Edition, with new emphasis on the relationship between pharmacokinetics and pharmacodynamics. Written by 70 leading researchers and practitioners, this book is a rigorous yet practical text on the application of pharmacokinetic methods, pharmacodynamic principles, and pharmacotherapeutic data for optimal, individualized drug therapy. This edition includes case studies that apply concepts to actual patient problems. New chapters cover tacrolimus, mycophenolic acid, sirolimus, antipsychotics, and critical evaluation of therapeutic drug monitoring methods. Other new features include more drawings and reference tables and an appendix on outcome studies with therapeutic drug monitoring.
Book Synopsis Applied Clinical Pharmacokinetics 3/E by : Larry A. Bauer
Download or read book Applied Clinical Pharmacokinetics 3/E written by Larry A. Bauer and published by McGraw Hill Professional. This book was released on 2014-01-05 with total page 881 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most current, hands-on book in the field, Applied Clinical Pharmacokinetics The perfect textbook for pharmacy students learning the clinical application of pharmacokinetics, which is the mathematical tools for modifying doages. Students like that each chapter includes sample problems throughout the chapter, with a ton of practice problems at the end. Answers for the practice problems are in the back, but not detailed like the sample problems) *Changes in the 3/e includes: *All chapters updated and revised, as needed, including critical new references *Antibiotic individualization and monitoring sections increases use of pharmacodynamic parameters (Cmax/MIC, AUC24/MIC, Time above MIC) in addition to pharmacokinetic parameters to adjust dosages *Anticonvulsants section includes 5 new agents (Fosphenytoin, Lamotrigine, Levetiracetam, Oxcarbazepine, Eslicarbazepine) *Immunosuppressants section includes 1 new agent (Sirolimus), About the Book Text focuses on the latest standardized techniques and approaches to patient-specific dosing and provides up-to-date information on more recently moniotored drugs. Features Clear, useful coverage of drug dosing and drug monitoring Clear and concise summary of pharmacokinetic and pharmacodynamic concepts Practical help with calculations and equations Focus on the latest standardized techniques and approaches to patient-specific dosing Up-to-date information on more recently monitored drugs Essential information on drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure All the information practitioners need on drug categories such as antibiotics, cardiovascular agents, anticonvulsants, and immunosuppressants Full coverage of drugs such as Aminoglycosides, Vancomycin, Digoxin, Phenytoin, Carbamazepine, Theophylline, Cyclosporine, Tacrolimus, and Lithium Student friendly approach to teaching pharmacokinetics--sample problems embedded into the text to allow for students to apply what they are learing. .
Book Synopsis Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents by : Michael W. Jann
Download or read book Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents written by Michael W. Jann and published by Springer. This book was released on 2016-03-02 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive resource on psychotropic medications, detailing the latest methods for defining their characteristics, their use in different patient populations, and drug-drug interactions; an important collection of information forclinicians, students, researchers, and members of the pharmaceutical industry alike. The first section provides the foundational principles of these drugs. Mathematical modeling of parameters that affect their entryto,and exit from, the central nervous system (CNS) compartment are presented on an individual basis and then applied to target populations with specific disease states. Methods and characteristics that inform the transfer of these drugs from the laboratory bench to use in patient care are discussed, including imaging techniques, genetics and physiological barriers, such as the blood-brain barrier. The second section describes the characteristics of specific agents,nominally arranged intodifferent therapeutic categories and with reference crossover use in different disease states. The pharmacologic characteristics of different drug formulations are explored in the context of their ability to improve patient adherence. The third section focuses on drug-drug interactions.Psychotropic medications from different categories are frequently prescribed together,or alongside medications used to treat comorbid conditions, and the information provided is directly relevant to the clinic, as a result. The clinical application of pharmacokinetics and pharmacodynamics of CNS agents has made significant progress over the past 50 years and new information is reported by numerous publications in psychiatry, neurology, and pharmacology.Our understanding of the interrelationship between these medications, receptors, drug transporters, as well as techniques for measurement and monitoring their interactions,isfrequently updated. However, with information presented on a host of different platforms, and in different formats, obtaining the full picture can be difficult. This title aims to collate this information into a single source that can be easily interpreted and applied towards patient care by the clinical practitioner, and act as a reference for all others who have an interest in psychopharmacological agents.
Book Synopsis Applied Pharmacokinetics by : William E. Evans
Download or read book Applied Pharmacokinetics written by William E. Evans and published by Applied Therapeutics, Incorporated. This book was released on 1992 with total page 1236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Third Edition of Applied Pharmacokinetics remains the gold standard by which all other clinical pharmacokinetics texts are measured. Written by leading pharmacokinetics researchers and practitioners, this book is the most advanced kinetics reference available. All chapters have been extensively updated or completely rewritten for this edition, and six new chapters have been added on pharmacodynamics, pharmacogenetics, pharmacokinetic considerations in the obese, dietary influences on drug disposition, zidovudine, and corticosteroids. Each chapter is tightly focused on the most important concepts and issues. Chapters on specific drugs are organized in a consistent format for quick, easy information retrieval. Major subheadings include Clinical Pharmacokinetics, Pharmacodynamics, Clinical Application of Pharmacokinetic Data, Analytical Methods, and Prospectus.
Book Synopsis Applied Pharmacology by : Stan K. Bardal
Download or read book Applied Pharmacology written by Stan K. Bardal and published by Elsevier Health Sciences. This book was released on 2011-01-01 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applied Pharmacology provides the essential details that are required for a solid understanding of pharmacology: how the drugs work, why side effects occur, and how the drugs are used clinically. Drs. Stan Bardal, Jason Waechter, and Doug Martin integrate the experience of the pharmacologist and the physician for a clinical focus that ensures a complete understanding of pharmacology.in print and online. Find information quickly and compare and contrast drugs easily thanks to a clear and consistent format without extraneous material. Apply basic pharmacology to clinical situations through integrated text. Enhance your learning with "For Your Information" sections detailing history and anecdotes for many agents within a given drug class. Access the fully searchable text online at studentconsult.com, along with 150 USMLE-style multiple choice questions, downloadable images, and online only references. Learn the essential details of pharmacology and enhance your understanding through an entirely new, fantastic art program. Gain a thorough understanding of key pharmacology components in a concise and efficient format
Book Synopsis Applied Biopharmaceutics and Pharmacokinetics by : Leon Shargel
Download or read book Applied Biopharmaceutics and Pharmacokinetics written by Leon Shargel and published by McGraw-Hill/Appleton & Lange. This book was released on 1993 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Basic and Applied Pharmacokinetics Self Assessment by : John E. Murphy
Download or read book Basic and Applied Pharmacokinetics Self Assessment written by John E. Murphy and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: To exercise the best possible judgment in patient care, medication plans should be selected for the maximum efficacy and safety for each individual patient. Be confident in your approach with ASHP's Basic & Applied Pharmacokinetics Self Assessment, a new resource from John E. Murphy, author of ASHP's Clinical Pharmacokinetics, Fifth Edition, which offers questions and exercises with answers and detailed solutions to help gauge your understanding.
Book Synopsis Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Third Edition by : Johan Gabrielsson
Download or read book Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Third Edition written by Johan Gabrielsson and published by CRC Press. This book was released on 2001-11-30 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a revised and very expanded version of the previous second edition of the book. "Pharmacokinetic and Pharmacodynamic Data Analysis" provides an introduction into pharmacokinetic and pharmacodynamic concepts using simple illustrations and reasoning. It describes ways in which pharmacodynamic and pharmacodynamic theory may be used to give insight into modeling questions and how these questions can in turn lead to new knowledge. This book differentiates itself from other texts in this area in that it bridges the gap between relevant theory and the actual application of the theory to real life situations. The book is divided into two parts; the first introduces fundamental principles of PK and PD concepts, and principles of mathematical modeling, while the second provides case studies obtained from drug industry and academia. Topics included in the first part include a discussion of the statistical principles of model fitting, including how to assess the adequacy of the fit of a model, as well as strategies for selection of time points to be included in the design of a study. The first part also introduces basic pharmacokinetic and pharmacodynamic concepts, including an excellent discussion of effect compartment (link) models as well as indirect response models. The second part of the text includes over 70 modeling case studies. These include a discussion of the selection of the model, derivation of initial parameter estimates and interpretation of the corresponding output. Finally, the authors discuss a number of pharmacodynamic modeling situations including receptor binding models, synergy, and tolerance models (feedback and precursor models). This book will be of interest to researchers, to graduate students and advanced undergraduate students in the PK/PD area who wish to learn how to analyze biological data and build models and to become familiar with new areas of application. In addition, the text will be of interest to toxicologists interested in learning about determinants of exposure and performing toxicokinetic modeling. The inclusion of the numerous exercises and models makes it an excellent primary or adjutant text for traditional PK courses taught in pharmacy and medical schools. A diskette is included with the text that includes all of the exercises and solutions using WinNonlin.
Book Synopsis Clinical Pharmacokinetics by : John E. Murphy
Download or read book Clinical Pharmacokinetics written by John E. Murphy and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the evolving practice of pharmacokinetics (PK), it is important to keep on top of the latest advances. John E. Murphy, a well-known leader in the field of clinical pharmacokinetics, has updated and expanded his widely-used textbook and reference. Clinical Pharmacokinetics, Sixth Edition includes the most current information, covering issues such as rational use of drug concentration measurements, changes in dosing obese patients, and considerations for a wider variety of drugs for special populations. There is also a new chapter focused on pharmacogenomics and its impact on pharmacokinetic parameters, as well as discussion of pharmacogenomics throughout the book. The new edition includes everything you need to know about pharmacokinetics today: Drugs, dosing, and therapeutic. Drug concentration measurements. New chapter on the impact of pharmacogenomics. Neonatal, pediatric, obese, and geriatric dosing. Dosing in renal disease and creatinine clearance estimation. Drugs sorted by family and as single drugs. Written in a straightforward style, with numerous charts and lists, the sixth edition makes complicated dosing and monitoring information easy to find and understand. Whether you are a student or practitioner, it is a resource you will turn to for reliable guidance throughout your pharmacy career.
Book Synopsis Basic Pharmacokinetics and Pharmacodynamics by : Sara E. Rosenbaum
Download or read book Basic Pharmacokinetics and Pharmacodynamics written by Sara E. Rosenbaum and published by John Wiley & Sons. This book was released on 2016-11-22 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated with new chapters and topics, this book provides a comprehensive description of all essential topics in contemporary pharmacokinetics and pharmacodynamics. It also features interactive computer simulations for students to experiment and observe PK/PD models in action. • Presents the essentials of pharmacokinetics and pharmacodynamics in a clear and progressive manner • Helps students better appreciate important concepts and gain a greater understanding of the mechanism of action of drugs by reinforcing practical applications in both the book and the computer modules • Features interactive computer simulations, available online through a companion website at: https://web.uri.edu/pharmacy/research/rosenbaum/sims/ • Adds new chapters on physiologically based pharmacokinetic models, predicting drug-drug interactions, and pharmacogenetics while also strengthening original chapters to better prepare students for more advanced applications • Reviews of the 1st edition: “This is an ideal textbook for those starting out … and also for use as a reference book …." (International Society for the Study of Xenobiotics) and “I could recommend Rosenbaum’s book for pharmacology students because it is written from a perspective of drug action . . . Overall, this is a well-written introduction to PK/PD …. “ (British Toxicology Society Newsletter)
Book Synopsis Introduction to Pharmacokinetics and Pharmacodynamics by : Thomas N. Tozer
Download or read book Introduction to Pharmacokinetics and Pharmacodynamics written by Thomas N. Tozer and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.
Book Synopsis Physiologically Based Pharmacokinetic (PBPK) Modeling by : Jeffrey W. Fisher
Download or read book Physiologically Based Pharmacokinetic (PBPK) Modeling written by Jeffrey W. Fisher and published by Academic Press. This book was released on 2020-05-20 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiologically Based Pharmacokinetic (PBPK) Modeling: Methods and Applications in Toxicology and Risk Assessment presents foundational principles, advanced techniques and applications of PBPK modeling. Contributions from experts in PBPK modeling cover topics such as pharmacokinetic principles, classical physiological models, the application of physiological models for dose-response and risk assessment, the use of in vitro information, and in silico methods. With end-of-chapter exercises that allow readers to practice and learn the skills associated with PBPK modeling, dose-response, and its applications to safety and risk assessments, this book is a foundational resource that provides practical coverage of PBPK modeling for graduate students, academics, researchers, and more. Provides end-of-chapter exercises to teach hands-on computational tools used in toxicology Supplies computer code and explanations and includes examples of applied models used in regulatory toxicology and research Authored by expert editors and contributors who are among the best PBPK modelers in the world
Book Synopsis Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition by : Leon Shargel
Download or read book Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition written by Leon Shargel and published by McGraw Hill Professional. This book was released on 2012-04-11 with total page 831 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics The field’s leading text for more than three decades Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition provides you with a basic understanding of the principles of biopharmaceutics and pharmacokinetics and applies these principles to drug product development, drug product performance and drug therapy. The revised and updated sixth edition is unique in teaching basic concepts that relate to understanding the complex issues associated with safe and efficacious drug therapy. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics will help you to: Understand the basic concepts in biopharmaceutics and pharmacokinetics. Use raw data and derive the pharmacokinetic models and parameters that best describe the process of drug absorption, distribution, and elimination Critically evaluate biopharmaceutic studies involving drug product equivalency and unequivalency Design and evaluate dosage regimens of drugs, using pharmacokinetic and biopharmaceutic parameters Detect potential clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Practical problems and clinical examples with discussions are included in each chapter to help you apply these principles to patient care and drug consultation situations. Chapter Objectives, Chapter Summaries, and Frequently Asked Questions along with additional application questions appear within each chapter to identify and focus on key concepts. Most of the chapters have been revised to reflect our current understanding of drug product performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy.
Book Synopsis Casebook in Clinical Pharmacokinetics and Drug Dosing by : Henry Cohen
Download or read book Casebook in Clinical Pharmacokinetics and Drug Dosing written by Henry Cohen and published by McGraw Hill Professional. This book was released on 2014-10-06 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: A STEP-BY-STEP APPROACH TO DESIGNING ACCURATE DOSING REGIMENS Casebook in Pharmacokinetics and Drug Dosing uses real-life cases to teach pharmacy students, pharmacists, and clinical pharmacists how to apply pharmacokinetics to formulate proper dosing regimens. In order to be as clinically relevant as possible, the book not only discusses drugs with readily available therapeutic serum levels, but places equal emphasis on high-alert agents with narrow therapeutic indexes. Each drug chapter is written by clinical pharmacists who have hands-on experience in drug dosing and includes an overview of the drug’s pharmacology, including: Indications Mec hanisms of action Toxicities Pharmacokinetics There is comprehensive review and discussion of each drug's bioavailability, volume of distribution, clearance, half-life, therapeutic drug level monitoring, drug interactions, dosing, and availability. Each chapter is enhanced by numerous patient cases with clear step-by-step answers and explanations. Calculations, equations, and dosing recommendations are provided for each case.
Book Synopsis Applied Pharmacology for Veterinary Technicians - E-Book by : Lisa Martini-Johnson
Download or read book Applied Pharmacology for Veterinary Technicians - E-Book written by Lisa Martini-Johnson and published by Elsevier Health Sciences. This book was released on 2020-07-21 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to calculate dosages accurately and administer drugs safely! Applied Pharmacology for Veterinary Technicians, 6th Edition shows you how to determine drug dosages, administer prescribed drugs to animals, and instruct clients about side effects and precautions. Coverage of drugs includes pharmacokinetics, pharmacodynamics, clinical uses, dosage forms, and adverse effects. An Evolve companion website offers animations of pharmacologic processes, practice with dosage calculations, narrated videos demonstrating drug administration techniques, and more. Written by veterinary technology educator Lisa Martini-Johnson, this resource provides the pharmacology knowledge you need to succeed as a vet tech! Quick-access format makes it easy to find important drug information, including clinical uses, dosage forms, and adverse side effects. Body systems organization follows a logical sequence of study. Illustrated, step-by-step procedures demonstrate proper administration techniques for common drug forms. Key terms, chapter outlines, Notes boxes, and learning objectives focus your learning and make studying easier. Proprietary drug names are listed with the generic drug names, highlighting drugs that have generic options. Companion Evolve website includes drug administration videos, drug calculators with accompanying word problems, animations of pharmacologic processes, and dosage calculation exercises. Dosage calculation exercises provide practice immediately after new information is presented. Review questions reinforce your understanding of key concepts, with answers located in the back of the book. Technician Notes provide useful hints and important reminders to help you avoid common errors and increase your efficiency on the job. NEW! Emergency Drugs chapter is added. UPDATED drug information keeps veterinary students current with the newest pharmacologic agents and their uses, adverse side effects, and dosage forms. NEW! Case studies at the end of every chapter provide students with real-world scenarios.
Book Synopsis Basic & Applied Pharmacokinetics Self Assessment by : John E. Murphy
Download or read book Basic & Applied Pharmacokinetics Self Assessment written by John E. Murphy and published by ASHP. This book was released on 2014-07-16 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mastery of pharmacokinetics is more important than ever. To exercise the best possible judgment in patient care, medication plans should be selected for the maximum efficacy and safety for each individual patient. Be confident in your approach with ASHP’s Basic & Applied Pharmacokinetics Self Assessment, a new resource from John E. Murphy, author of ASHP’s Clinical Pharmacokinetics, Fifth Edition, which offers questions and exercises with answers and detailed solutions to help gauge your understanding. Whether you are a student, a new pharmacist, or a long-time practitioner, it is essential that you not only acquire and maintain your therapeutic knowledge, but also stay on top of new developments in pharmacokinetics. This is a valuable review book designed to test skills for using equations and the application of pharmacokinetic parameters. It is the perfect book to review content you have learned and practiced, in addition to learning new areas not previously covered in your training. As an added feature, the YouTube channel, Basic & Applied Pharmacokinetics Self Assessment Videos, is available as a complementary companion to the book, which includes a library of videos created by John Murphy to help you through the major pain points and help further support your self assessment.
