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Applied Clinical Pharmacokinetics
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Book Synopsis Applied Clinical Pharmacokinetics by : Larry A. Bauer
Download or read book Applied Clinical Pharmacokinetics written by Larry A. Bauer and published by McGraw Hill Professional. This book was released on 2007-09-22 with total page 842 pages. Available in PDF, EPUB and Kindle. Book excerpt: New sections on dosing strategies in all chapters. New chapter on sirolimus under the Immunosuppressants section. Essential information on drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure. 30% of chapters extensively revised, others lightly updated
Book Synopsis Applied Clinical Pharmacokinetics 3/E by : Larry A. Bauer
Download or read book Applied Clinical Pharmacokinetics 3/E written by Larry A. Bauer and published by McGraw Hill Professional. This book was released on 2014-01-05 with total page 881 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most current, hands-on book in the field, Applied Clinical Pharmacokinetics The perfect textbook for pharmacy students learning the clinical application of pharmacokinetics, which is the mathematical tools for modifying doages. Students like that each chapter includes sample problems throughout the chapter, with a ton of practice problems at the end. Answers for the practice problems are in the back, but not detailed like the sample problems) *Changes in the 3/e includes: *All chapters updated and revised, as needed, including critical new references *Antibiotic individualization and monitoring sections increases use of pharmacodynamic parameters (Cmax/MIC, AUC24/MIC, Time above MIC) in addition to pharmacokinetic parameters to adjust dosages *Anticonvulsants section includes 5 new agents (Fosphenytoin, Lamotrigine, Levetiracetam, Oxcarbazepine, Eslicarbazepine) *Immunosuppressants section includes 1 new agent (Sirolimus), About the Book Text focuses on the latest standardized techniques and approaches to patient-specific dosing and provides up-to-date information on more recently moniotored drugs. Features Clear, useful coverage of drug dosing and drug monitoring Clear and concise summary of pharmacokinetic and pharmacodynamic concepts Practical help with calculations and equations Focus on the latest standardized techniques and approaches to patient-specific dosing Up-to-date information on more recently monitored drugs Essential information on drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure All the information practitioners need on drug categories such as antibiotics, cardiovascular agents, anticonvulsants, and immunosuppressants Full coverage of drugs such as Aminoglycosides, Vancomycin, Digoxin, Phenytoin, Carbamazepine, Theophylline, Cyclosporine, Tacrolimus, and Lithium Student friendly approach to teaching pharmacokinetics--sample problems embedded into the text to allow for students to apply what they are learing. .
Book Synopsis Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents by : Michael W. Jann
Download or read book Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents written by Michael W. Jann and published by Springer. This book was released on 2016-03-02 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive resource on psychotropic medications, detailing the latest methods for defining their characteristics, their use in different patient populations, and drug-drug interactions; an important collection of information forclinicians, students, researchers, and members of the pharmaceutical industry alike. The first section provides the foundational principles of these drugs. Mathematical modeling of parameters that affect their entryto,and exit from, the central nervous system (CNS) compartment are presented on an individual basis and then applied to target populations with specific disease states. Methods and characteristics that inform the transfer of these drugs from the laboratory bench to use in patient care are discussed, including imaging techniques, genetics and physiological barriers, such as the blood-brain barrier. The second section describes the characteristics of specific agents,nominally arranged intodifferent therapeutic categories and with reference crossover use in different disease states. The pharmacologic characteristics of different drug formulations are explored in the context of their ability to improve patient adherence. The third section focuses on drug-drug interactions.Psychotropic medications from different categories are frequently prescribed together,or alongside medications used to treat comorbid conditions, and the information provided is directly relevant to the clinic, as a result. The clinical application of pharmacokinetics and pharmacodynamics of CNS agents has made significant progress over the past 50 years and new information is reported by numerous publications in psychiatry, neurology, and pharmacology.Our understanding of the interrelationship between these medications, receptors, drug transporters, as well as techniques for measurement and monitoring their interactions,isfrequently updated. However, with information presented on a host of different platforms, and in different formats, obtaining the full picture can be difficult. This title aims to collate this information into a single source that can be easily interpreted and applied towards patient care by the clinical practitioner, and act as a reference for all others who have an interest in psychopharmacological agents.
Book Synopsis Applied Clinical Pharmacokinetics by : Larry A. Bauer
Download or read book Applied Clinical Pharmacokinetics written by Larry A. Bauer and published by McGraw-Hill/Appleton & Lange. This book was released on 2001 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improving upon and updating the information and format of the leading competing clinical pharmacokinetic text, Dr. Bauer, a nationally recognized leader in the field of pharmacokinetics has conceived a text for today and tomorrow's pharmacy student and practitioner. The text emphasizes the practical aspects of drug dosing for agents that have serum concentrations commonly available from clinical laboratories. Filling a hole in our list between Shargel and Schumacher, this new book will focus on patient specific drug dosing, thereby emphasizing the standard clinical pharmacokinetic dosing techniques.
Book Synopsis Clinical Pharmacokinetics by : John E. Murphy
Download or read book Clinical Pharmacokinetics written by John E. Murphy and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the evolving practice of pharmacokinetics (PK), it is important to keep on top of the latest advances. John E. Murphy, a well-known leader in the field of clinical pharmacokinetics, has updated and expanded his widely-used textbook and reference. Clinical Pharmacokinetics, Sixth Edition includes the most current information, covering issues such as rational use of drug concentration measurements, changes in dosing obese patients, and considerations for a wider variety of drugs for special populations. There is also a new chapter focused on pharmacogenomics and its impact on pharmacokinetic parameters, as well as discussion of pharmacogenomics throughout the book. The new edition includes everything you need to know about pharmacokinetics today: Drugs, dosing, and therapeutic. Drug concentration measurements. New chapter on the impact of pharmacogenomics. Neonatal, pediatric, obese, and geriatric dosing. Dosing in renal disease and creatinine clearance estimation. Drugs sorted by family and as single drugs. Written in a straightforward style, with numerous charts and lists, the sixth edition makes complicated dosing and monitoring information easy to find and understand. Whether you are a student or practitioner, it is a resource you will turn to for reliable guidance throughout your pharmacy career.
Book Synopsis Applied Clinical Pharmacokinetics by : Larry Bauer
Download or read book Applied Clinical Pharmacokinetics written by Larry Bauer and published by McGraw-Hill Prof Med/Tech. This book was released on 2008-06-24 with total page 843 pages. Available in PDF, EPUB and Kindle. Book excerpt: The easiest and most trusted way to learn the clinical application of pharmacokinetics 5 STAR DOODY'S REVIEW! "This is an important reference that teaches clinically relevant pharmacokinetic dosing and therapeutic drug monitoring tools. This second edition includes updated information on dosing immunosuppressants, as well as dosing concepts in pediatric and hemodialysis patients. The book is intended as an instructive tool in pharmacokinetics for healthcare practitioners who wish to learn these concepts and apply them in their clinical practice. The book satisfies its objectives, outlining important pharmacokinetic concepts in an organized and easy to understand fashion. It is also written by a pharmacist with extensive experience in pharmacokinetics and includes clinically pertinent pearls for individual drugs. This second edition succeeds at providing updated information on pharmacokinetic concepts. The book presents information in a manner that allows readers to teach themselves about pharmacokinetic dosing and to update their knowledge about clinically relevant concepts for the medications. These concepts are critical because medications are far too often dosed without individual patient characteristics (weight, age, concomitant medications) in mind. It is important to individualize dosing based on pharmacokinetic methods, to monitor levels, and to adjust subsequent dosing based on peaks, troughs, renal, and hepatic function." -- Doody's The most current, hands-on book in the field, Applied Clinical Pharmacokinetics gives you clear and useful coverage of drug dosing and drug monitoring that no other text can match. It offers the latest standardized techniques and approaches to patient-specific dosing plus new information on more recent pharmacokinetically monitored drugs. Written by a nationally recognized authority in pharmacokinetics, Applied Clinical Pharmacokinetics provides essential information covered in pharmaceutics, pharmacokinetics, therapeutics, and clinical pharmacy courses. It can be also be used as a clinical refresher to brush up on key concepts and procedures. FEATURES NEW! High-yield sections on dosing strategies in all chapters NEW! Up-to-date, ready-to-use information on monitored drugs Valuable coverage of drug dosing in special populations, including patients with renal and hepatic disease, obesity, and congestive heart failure and patients on dialysis All the information that you need on drug categories such as antibiotics, cardiovascular agents, anticonvulsants, and immunosuppressants Tools that simplify learning throughout, such as an introductory chapter on clinical pharmacokinetic and pharmacodynamic concepts, examples of calculations, and problems with answers and explanations at the end of each chapter
Book Synopsis Casebook in Clinical Pharmacokinetics and Drug Dosing by : Henry Cohen
Download or read book Casebook in Clinical Pharmacokinetics and Drug Dosing written by Henry Cohen and published by McGraw Hill Professional. This book was released on 2014-10-06 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: A STEP-BY-STEP APPROACH TO DESIGNING ACCURATE DOSING REGIMENS Casebook in Pharmacokinetics and Drug Dosing uses real-life cases to teach pharmacy students, pharmacists, and clinical pharmacists how to apply pharmacokinetics to formulate proper dosing regimens. In order to be as clinically relevant as possible, the book not only discusses drugs with readily available therapeutic serum levels, but places equal emphasis on high-alert agents with narrow therapeutic indexes. Each drug chapter is written by clinical pharmacists who have hands-on experience in drug dosing and includes an overview of the drug’s pharmacology, including: Indications Mec hanisms of action Toxicities Pharmacokinetics There is comprehensive review and discussion of each drug's bioavailability, volume of distribution, clearance, half-life, therapeutic drug level monitoring, drug interactions, dosing, and availability. Each chapter is enhanced by numerous patient cases with clear step-by-step answers and explanations. Calculations, equations, and dosing recommendations are provided for each case.
Book Synopsis Applied Pharmacokinetics & Pharmacodynamics by : Michael E. Burton
Download or read book Applied Pharmacokinetics & Pharmacodynamics written by Michael E. Burton and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 924 pages. Available in PDF, EPUB and Kindle. Book excerpt: The definitive advanced-level clinical pharmacokinetics text is now in its Fourth Edition, with new emphasis on the relationship between pharmacokinetics and pharmacodynamics. Written by 70 leading researchers and practitioners, this book is a rigorous yet practical text on the application of pharmacokinetic methods, pharmacodynamic principles, and pharmacotherapeutic data for optimal, individualized drug therapy. This edition includes case studies that apply concepts to actual patient problems. New chapters cover tacrolimus, mycophenolic acid, sirolimus, antipsychotics, and critical evaluation of therapeutic drug monitoring methods. Other new features include more drawings and reference tables and an appendix on outcome studies with therapeutic drug monitoring.
Book Synopsis Biopharmaceutics and Clinical Pharmacokinetics by : Notari
Download or read book Biopharmaceutics and Clinical Pharmacokinetics written by Notari and published by Routledge. This book was released on 2017-11-22 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: For a decade and a half, Biopharmaceutics and Clinical Pharmacokinetics has been used in theclassrooms around the world as an introductory textbook on biophannaceutics and phannacokinetics. Now, the new Fourth Edition, Revised and Expanded further enhances the preceding editions'proven features, introducing significant advances in clinical pharmacokinetics, pharmacokineticdesign of drugs and dosage forms, and model-independent analyses. Still usable without prior knowledge of calculus or kinetics, this successfully implemented workbookmaintains a carefully graduated "building block" presentation, incorporating sample problemsand exercises throughout for a thorough understanding of the material.Biopharmaceutics and Clinical Pharmacokinetics features a growth-oriented format that systematicallydevelops and interrelates all subject matter .. . introduces basic theory and fields of application... emphasizes model-independent pharmacokinetic analyses ... presents biopharmaceutical aspectsof product design and evaluation .. . offers a unique approach to teaching dosage regimen design andindividualization . .. and considers structural modification of drug molecules for problems associatedwith pharmacokinetics. As a comprehensive coverage of the basic principles and the recent achievements in the field, noother textbook does as much for students of pharmacy, pharmacology, medicinal chemistry, andmedicine, or for scientists who desire a simple but thorough introduction to theory and application.
Book Synopsis Clinical Pharmacokinetics Handbook by : Larry Bauer
Download or read book Clinical Pharmacokinetics Handbook written by Larry Bauer and published by McGraw-Hill Medical. This book was released on 2006 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed for pharmacists and clinicians responsible for adjusting drug dosages based on the patient blood serum concentrations and other parameters, this indispensable, portable reference offers a variety of ways to perform pharmacokinetic calculations. Features calculation methods, algorithms for choosing the best calculation method, and case studies.
Book Synopsis Clinical Pharmacokinetics by : Stephen H. Curry
Download or read book Clinical Pharmacokinetics written by Stephen H. Curry and published by CRC Press. This book was released on 1988-12-15 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Pharmacokinetics: The MCQ Approach is a self-teaching guide to the subject. The reader is guided through the principles of the subject as they are applied to increasingly complex situations. The volume contains a number of single and multiple-choice questions, many requiring graphing and calculation techniques and is intended as an instructional tool both for the student and practicing professional. The volume aims to test to reader's analytical skills when presented with experimental data. It will be of interest to students of pharmacy, clinical pharmacology and biopharmaceutics as well as to instructors in those subjects, both in the teaching of the subject and in the design of examination material.
Book Synopsis Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Third Edition by : Johan Gabrielsson
Download or read book Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Third Edition written by Johan Gabrielsson and published by CRC Press. This book was released on 2001-11-30 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a revised and very expanded version of the previous second edition of the book. "Pharmacokinetic and Pharmacodynamic Data Analysis" provides an introduction into pharmacokinetic and pharmacodynamic concepts using simple illustrations and reasoning. It describes ways in which pharmacodynamic and pharmacodynamic theory may be used to give insight into modeling questions and how these questions can in turn lead to new knowledge. This book differentiates itself from other texts in this area in that it bridges the gap between relevant theory and the actual application of the theory to real life situations. The book is divided into two parts; the first introduces fundamental principles of PK and PD concepts, and principles of mathematical modeling, while the second provides case studies obtained from drug industry and academia. Topics included in the first part include a discussion of the statistical principles of model fitting, including how to assess the adequacy of the fit of a model, as well as strategies for selection of time points to be included in the design of a study. The first part also introduces basic pharmacokinetic and pharmacodynamic concepts, including an excellent discussion of effect compartment (link) models as well as indirect response models. The second part of the text includes over 70 modeling case studies. These include a discussion of the selection of the model, derivation of initial parameter estimates and interpretation of the corresponding output. Finally, the authors discuss a number of pharmacodynamic modeling situations including receptor binding models, synergy, and tolerance models (feedback and precursor models). This book will be of interest to researchers, to graduate students and advanced undergraduate students in the PK/PD area who wish to learn how to analyze biological data and build models and to become familiar with new areas of application. In addition, the text will be of interest to toxicologists interested in learning about determinants of exposure and performing toxicokinetic modeling. The inclusion of the numerous exercises and models makes it an excellent primary or adjutant text for traditional PK courses taught in pharmacy and medical schools. A diskette is included with the text that includes all of the exercises and solutions using WinNonlin.
Book Synopsis Applied Biopharmaceutics and Pharmacokinetics by : Leon Shargel
Download or read book Applied Biopharmaceutics and Pharmacokinetics written by Leon Shargel and published by McGraw-Hill/Appleton & Lange. This book was released on 1993 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Basic and Applied Pharmacokinetics Self Assessment by : John E. Murphy
Download or read book Basic and Applied Pharmacokinetics Self Assessment written by John E. Murphy and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: To exercise the best possible judgment in patient care, medication plans should be selected for the maximum efficacy and safety for each individual patient. Be confident in your approach with ASHP's Basic & Applied Pharmacokinetics Self Assessment, a new resource from John E. Murphy, author of ASHP's Clinical Pharmacokinetics, Fifth Edition, which offers questions and exercises with answers and detailed solutions to help gauge your understanding.
Book Synopsis Introduction to Pharmacokinetics and Pharmacodynamics by : Thomas N. Tozer
Download or read book Introduction to Pharmacokinetics and Pharmacodynamics written by Thomas N. Tozer and published by Lippincott Williams & Wilkins. This book was released on 2006 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.
Book Synopsis Applied Pharmacokinetics by : William E. Evans
Download or read book Applied Pharmacokinetics written by William E. Evans and published by Applied Therapeutics, Incorporated. This book was released on 1992 with total page 1236 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Third Edition of Applied Pharmacokinetics remains the gold standard by which all other clinical pharmacokinetics texts are measured. Written by leading pharmacokinetics researchers and practitioners, this book is the most advanced kinetics reference available. All chapters have been extensively updated or completely rewritten for this edition, and six new chapters have been added on pharmacodynamics, pharmacogenetics, pharmacokinetic considerations in the obese, dietary influences on drug disposition, zidovudine, and corticosteroids. Each chapter is tightly focused on the most important concepts and issues. Chapters on specific drugs are organized in a consistent format for quick, easy information retrieval. Major subheadings include Clinical Pharmacokinetics, Pharmacodynamics, Clinical Application of Pharmacokinetic Data, Analytical Methods, and Prospectus.
Book Synopsis Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications by : Hartmut Derendorf
Download or read book Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications written by Hartmut Derendorf and published by Lippincott Williams & Wilkins. This book was released on 2019-07-11 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated with the latest clinical advances, Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition , explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.
