Applied Genomics And Public Health

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Applied Genomics and Public Health

Author : George P. Patrinos
Publisher : Academic Press
ISBN 13 : 0128136960
Total Pages : 406 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Applied Genomics and Public Health by : George P. Patrinos

Download or read book Applied Genomics and Public Health written by George P. Patrinos and published by Academic Press. This book was released on 2019-11-13 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applied Genomics and Public Health examines the interdisciplinary and growing area of how evidence-based genomic knowledge can be applied to public health, population health, healthcare and health policies. The book gathers experts from a variety of disciplines, including life sciences, social sciences, and health care to develop a comprehensive overview of the field. In addition, the book delves into subjects such as pharmacogenomics, genethics, big data, data translation and analysis, economic evaluation, genomic awareness and education, sociology, pricing and reimbursement, policy measures and economic evaluation in genomic medicine. This book is essential reading for researchers and students exploring applications of genomics to population and public health. In addition, it is ideal for those in the biomedical sciences, medical sociologists, healthcare professionals, nurses, regulatory bodies and health economists interested in learning more about this growing field. Explores the growing application of genomics to population and public health Features internationally renowned contributors from a variety of related fields Contains chapters on important topics such as genomic data sharing, genethics and public health genomics, genomics and sociology, and regulatory aspects of genomic medicine and pharmacogenomics

Medical and Health Genomics

Author : Dhavendra Kumar
Publisher : Academic Press
ISBN 13 : 0127999221
Total Pages : 358 pages
Book Rating : 4.1/5 (279 download)

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Book Synopsis Medical and Health Genomics by : Dhavendra Kumar

Download or read book Medical and Health Genomics written by Dhavendra Kumar and published by Academic Press. This book was released on 2016-06-04 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems

Public Health Genomics

Author : Claudia N. Mikail
Publisher : John Wiley & Sons
ISBN 13 : 0470454415
Total Pages : 431 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Public Health Genomics by : Claudia N. Mikail

Download or read book Public Health Genomics written by Claudia N. Mikail and published by John Wiley & Sons. This book was released on 2008-11-03 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Centers for Disease Control (CDC) has recognized genomics as a priority area in public health education. To help public health students and professionals achieve proficiency in the language of genetics and attain genomics competencies delineated by the CDC, this book offers an introduction to basic molecular genetics and discusses the relevance of genomics to such key public health issues as environmental health, ethnic health disparities, health policy and law, research ethics, maternal and child health, clinical preventive medicine, health behavior, health economics, and communicable disease control. Presented in a context that is easy to understand, the book serves as an accessible portal of entry into the world of public health genomics.

Genomic and Precision Medicine

Author : Geoffrey S. Ginsburg
Publisher : Academic Press
ISBN 13 : 0128006544
Total Pages : 370 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Genomic and Precision Medicine by : Geoffrey S. Ginsburg

Download or read book Genomic and Precision Medicine written by Geoffrey S. Ginsburg and published by Academic Press. This book was released on 2017-03-30 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic and Precision Medicine: Primary Care, Third Edition is an invaluable resource on the state-of-the-art tools, technologies and policy issues that are required to fully realize personalized health care in the area of primary care. One of the major areas where genomic and personalized medicine is most active is the realm of the primary care practitioner. Risk, family history, personal genomics and pharmacogenomics are becoming increasingly important to the PCP and their patients, and this book discusses the implications as they relate to primary care practitioners. Presents a comprehensive volume for primary care providers Provides succinct commentary and key learning points that will assist providers with their local needs for the implementation of genomic and personalized medicine Includes a current overview on major opportunities for genomic and personalized medicine in practice Highlights case studies that illustrate the practical use of genomics in the management in patients

Genomics of Rare Diseases

Author : Claudia Gonzaga-Jauregui
Publisher : Academic Press
ISBN 13 : 0128204362
Total Pages : 316 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Genomics of Rare Diseases by : Claudia Gonzaga-Jauregui

Download or read book Genomics of Rare Diseases written by Claudia Gonzaga-Jauregui and published by Academic Press. This book was released on 2021-06-12 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomics of Rare Diseases: Understanding Disease Genetics Using Genomic Approaches, a new volume in the Translational and Applied Genomics series, offers readers a broad understanding of current knowledge on rare diseases through a genomics lens. This clear understanding of the latest molecular and genomic technologies used to elucidate the molecular causes of more than 5,000 genetic disorders brings readers closer to unraveling many more that remain undefined and undiscovered. The challenges associated with performing rare disease research are also discussed, as well as the opportunities that the study of these disorders provides for improving our understanding of disease architecture and pathophysiology. Leading chapter authors in the field discuss approaches such as karyotyping and genomic sequencing for the better diagnosis and treatment of conditions including recessive diseases, dominant and X-linked disorders, de novo mutations, sporadic disorders and mosaicism. Compiles applied case studies and methodologies, enabling researchers, clinicians and healthcare providers to effectively classify DNA variants associated with disease and patient phenotypes Discusses the main challenges in studying the genetics of rare diseases through genomic approaches and possible or ongoing solutions Explores opportunities for novel therapeutics Features chapter contributions from leading researchers and clinicians

Economic Evaluation in Genomic Medicine

Author : Vasilios Fragoulakis
Publisher : Academic Press
ISBN 13 : 0128016116
Total Pages : 174 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Economic Evaluation in Genomic Medicine by : Vasilios Fragoulakis

Download or read book Economic Evaluation in Genomic Medicine written by Vasilios Fragoulakis and published by Academic Press. This book was released on 2015-03-20 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Economic Evaluation in Genomic Medicine introduces health economics and economic evaluation to genomic clinicians and researchers, while also introducing the topic to health economists. Each chapter includes an executive summary, questions, and case studies, along with supplementary online materials, including process guides, maps, flow charts, diagrams, and economic evaluation spreadsheets to enhance the learning process. The text can easily be used as course material for related graduate and undergraduate courses, providing a succinct overview of the existing, state-of-the-art application of economic evaluation to genomic healthcare and precision medicine. Interrelates economic evaluation and genomic medicine Instructs healthcare professionals and bioscientists about economic evaluation in genomic medicine Teaches health economists about application of economic evaluation in genomic medicine Introduces health economics and economic evaluation to clinicians and researchers involved in genomics Includes process guides, maps, flow charts and diagrams

Human Genome Informatics

Author : Christophe Lambert
Publisher : Academic Press
ISBN 13 : 0128134313
Total Pages : 314 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Human Genome Informatics by : Christophe Lambert

Download or read book Human Genome Informatics written by Christophe Lambert and published by Academic Press. This book was released on 2018-08-02 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Genome Informatics: Translating Genes into Health examines the most commonly used electronic tools for translating genomic information into clinically meaningful formats. By analyzing and comparing interpretation methods of whole genome data, the book discusses the possibilities of their application in genomic and translational medicine. Topics such as electronic decision-making tools, translation algorithms, interpretation and translation of whole genome data for rare diseases are thoroughly explored. In addition, discussions of current human genome databases and the possibilities of big data in genomic medicine are presented. With an updated approach on recent techniques and current human genomic databases, the book is a valuable source for students and researchers in genome and medical informatics. It is also ideal for workers in the bioinformatics industry who are interested in recent developments in the field. Provides an overview of the most commonly used electronic tools to translate genomic information Brings an update on the existing human genomic databases that directly impact genome interpretation Summarizes and comparatively analyzes interpretation methods of whole genome data and their application in genomic medicine

Public Health Genomics and International Wealth Creation

Author : Ebomoyi, E. William
Publisher : IGI Global
ISBN 13 : 1466685603
Total Pages : 463 pages
Book Rating : 4.4/5 (666 download)

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Book Synopsis Public Health Genomics and International Wealth Creation by : Ebomoyi, E. William

Download or read book Public Health Genomics and International Wealth Creation written by Ebomoyi, E. William and published by IGI Global. This book was released on 2016-03-30 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2003, the secrets of the human genome were cracked open, creating a flurry of anticipation (and more than a little commercial buzz) about the role that genetic modification would play in years to come. This burgeoning field stands poised to redefine old paradigms and reshape industries such as medicine, agriculture, pharmacology, and biotechnology. Public Health Genomics and International Wealth Creation seeks to explore new opportunities and challenges in genomic commercialization by presenting a roadmap of current research, setting forth clear guidelines for how genomics can be wielded safely and ethically in a manner concordant with public welfare. Addressing problems such as chronic disease, world hunger, and global economic disparity, this book is an essential reference source for doctors, bioethicists, human genome specialists, and scientists in the fields of genetics and genomics. This authored monograph contains chapters on topics ranging from agronomics and biotechnology to commercial genomics, genome sequencing, cancer genomics, and more.

Genomic and Precision Medicine

Author : Geoffrey S. Ginsburg
Publisher : Academic Press
ISBN 13 : 0128006536
Total Pages : 379 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Genomic and Precision Medicine by : Geoffrey S. Ginsburg

Download or read book Genomic and Precision Medicine written by Geoffrey S. Ginsburg and published by Academic Press. This book was released on 2022-04-09 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field. Provides a comprehensive volume written and edited by oncology genomic specialists for oncology health providers Includes succinct commentary and key learning points that will assist providers with their local needs for implementation of genomic and personalized medicine into practice Presents an up-to-date overview on major opportunities for genomic and personalized medicine in practice Covers case studies that highlight the practical use of genomics in the management of patients

Clinical DNA Variant Interpretation

Author : Conxi Lázaro
Publisher : Academic Press
ISBN 13 : 0128205202
Total Pages : 436 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Clinical DNA Variant Interpretation by : Conxi Lázaro

Download or read book Clinical DNA Variant Interpretation written by Conxi Lázaro and published by Academic Press. This book was released on 2021-02-27 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical DNA Variant Interpretation: Theory and Practice, a new volume in the Translational and Applied Genomics series, covers foundational aspects, modes of analysis, technology, disease and disorder specific case studies, and clinical integration. This book provides a deep theoretical background, as well as applied case studies and methodology, enabling researchers, clinicians and healthcare providers to effectively classify DNA variants associated with disease and patient phenotypes. Practical chapters discuss genomic variant interpretation, terminology and nomenclature, international consensus guidelines, population allele frequency, functional evidence transcripts for RNA, proteins, and enzymes, somatic mutations, somatic profiling, and much more. Compiles best practices, methods and sound evidence for DNA variant classification in one applied volume Features chapter contributions from international leaders in the field Includes practical examples of variant classification for common and rare disorders, and across clinical phenotypes

Genomic Medicine in Emerging Economies

Author : George Patrinos
Publisher : Academic Press
ISBN 13 : 0128115513
Total Pages : 204 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Genomic Medicine in Emerging Economies by : George Patrinos

Download or read book Genomic Medicine in Emerging Economies written by George Patrinos and published by Academic Press. This book was released on 2018-06-29 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic Medicine in Resource-limited Countries: Genomics for Every Nation provides in-depth analysis and key examples of the implementation of medical genomics in low-income nations across the globe, demonstrating how this advancing medical science has not only transformed health systems, but also led to improved patient care in Indonesian, Nepalese, Chilean, Malaysian, Tanzanian, Argentinian, Chinese, Sri Lankan and Columbian populations, among others. In addition to defining tools, diagnostics and treatment pathways at the population-wide level for medical geneticists, genomic researchers and public health workers, this book offers a case-study based approach that helps users understand how genomic medicine is used in disease-management. Examines essential concepts and protocols, and economic, social and legal considerations related to the implementation of genomic medicine in resource-limited nations Features concrete success stories of the implementation of medical genomics in Indonesian, Nepalese, Chilean, Malaysian, Tanzanian, Argentinian, Chinese, Sri Lankan and Columbian populations, amongst others Provides tools, diagnostics and treatment pathways for medical geneticists, genomic researchers and public health workers to apply in their own work Establishes clear precedents on how genomic technologies can be accessed by nations with limited means and financial support for healthcare

Applied Genomics of Foodborne Pathogens

Author : Xiangyu Deng
Publisher : Springer
ISBN 13 : 3319437518
Total Pages : 205 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Applied Genomics of Foodborne Pathogens by : Xiangyu Deng

Download or read book Applied Genomics of Foodborne Pathogens written by Xiangyu Deng and published by Springer. This book was released on 2017-01-23 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a timely and thorough snapshot into the emerging and fast evolving area of applied genomics of foodborne pathogens. Driven by the drastic advance of whole genome shot gun sequencing (WGS) technologies, genomics applications are becoming increasingly valuable and even essential in studying, surveying and controlling foodborne microbial pathogens. The vast opportunities brought by this trend are often at odds with the lack of bioinformatics know-how among food safety and public health professionals, since such expertise is not part of a typical food microbiology curriculum and skill set. Further complicating the challenge is the large and ever evolving body of bioinformatics tools that can obfuscate newcomers to this area. Although reviews, tutorials and books are not in short supply in the fields of bioinformatics and genomics, until now there has not been a comprehensive and customized source of information designed for and accessible to microbiologists interested in applying cutting-edge genomics in food safety and public health research. This book fills this void with a well-selected collection of topics, case studies, and bioinformatics tools contributed by experts at the forefront of foodborne pathogen genomics research.

Genomic Medicine

Author : Dhavendra Kumar
Publisher : Oxford Monographs on Medical G
ISBN 13 : 019989602X
Total Pages : 853 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis Genomic Medicine by : Dhavendra Kumar

Download or read book Genomic Medicine written by Dhavendra Kumar and published by Oxford Monographs on Medical G. This book was released on 2014-10-15 with total page 853 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preceded by Genomics and clinical medicine / edited by Dhavendra Kumar. [First edition]. 2008.

Secondary Findings in Genomic Research

Author :
Publisher : Academic Press
ISBN 13 : 0128165499
Total Pages : 244 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Secondary Findings in Genomic Research by :

Download or read book Secondary Findings in Genomic Research written by and published by Academic Press. This book was released on 2020-03-18 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Secondary Findings in Genomic Research offers a single, highly accessible resource on interpreting, managing and disclosing secondary findings in genomic research. With chapters written by experts in the field, this book is the first to concisely explain the ethical and practical issues raised by secondary genomics findings for a multi and interdisciplinary audience of genomic researchers, translational scientists, clinicians, medical students, genetic counselors, ethicists, legal experts and law students, public policy specialists and regulators. Contributors from Europe, North America, and Asia effectively synthesize perspectives from a spectrum of different scientific, societal, and global contexts, and offer pragmatic approaches to a range of topics, including oversight, governance and policy surrounding secondary genomic results, criteria for identifying results for return, communication and consent, stakeholders' attitudes and perspectives, disclosing results, and clinical, patient-centered protocols. Thoroughly addresses the scientific, ethical, practical and clinical issues raised by secondary findings resulting from genomic research, including active debate and challenges in the field Provides researchers, clinicians, regulators, and stakeholders with a holistic, interdisciplinary approach to interpreting, managing and disclosing secondary findings Brings together expert analysis from scholars across Europe, North America, and Asia representing a wide variety of scientific and societal contexts

Genomic Epidemiology Data Infrastructure Needs for SARS-CoV-2

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309680948
Total Pages : 111 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Genomic Epidemiology Data Infrastructure Needs for SARS-CoV-2 by : National Academies of Sciences, Engineering, and Medicine

Download or read book Genomic Epidemiology Data Infrastructure Needs for SARS-CoV-2 written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-09-29 with total page 111 pages. Available in PDF, EPUB and Kindle. Book excerpt: In December 2019, new cases of severe pneumonia were first detected in Wuhan, China, and the cause was determined to be a novel beta coronavirus related to the severe acute respiratory syndrome (SARS) coronavirus that emerged from a bat reservoir in 2002. Within six months, this new virusâ€"SARS coronavirus 2 (SARS-CoV-2)â€"has spread worldwide, infecting at least 10 million people with an estimated 500,000 deaths. COVID-19, the disease caused by SARS-CoV-2, was declared a public health emergency of international concern on January 30, 2020 by the World Health Organization (WHO) and a pandemic on March 11, 2020. To date, there is no approved effective treatment or vaccine for COVID-19, and it continues to spread in many countries. Genomic Epidemiology Data Infrastructure Needs for SARS-CoV-2: Modernizing Pandemic Response Strategies lays out a framework to define and describe the data needs for a system to track and correlate viral genome sequences with clinical and epidemiological data. Such a system would help ensure the integration of data on viral evolution with detection, diagnostic, and countermeasure efforts. This report also explores data collection mechanisms to ensure a representative global sample set of all relevant extant sequences and considers challenges and opportunities for coordination across existing domestic, global, and regional data sources.

Nutrition and Genomics

Author : David Castle
Publisher : Academic Press
ISBN 13 : 9780080920825
Total Pages : 312 pages
Book Rating : 4.9/5 (28 download)

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Book Synopsis Nutrition and Genomics by : David Castle

Download or read book Nutrition and Genomics written by David Castle and published by Academic Press. This book was released on 2009-04-14 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrigenomics is the rapidly developing field of science that studies nutrient-gene interaction. This field has broad implications for understanding the interaction of human genomics and nutrition, but can also have very specific implications for individual dietary recommendations in light of personal genetics. Predicted applications for nutrigenomics include genomics-based dietary guidelines and personalized nutrition based on individual genetic tests. These developments have sweeping ethical, legal and regulatory implications for individuals, corporations and governments. This book brings together experts in ethics, law, regulatory analysis, and communication studies to identify and address relevant issues in the emerging field of nutritional genomics. Contributing authors are experts in the social aspects of biotechnology innovation, with expertise in nutrigenomics. From addressing the concern that nutrigenomics will transform food into medicine and undermine pleasures associated with eating to the latest in the science of nutrigenomics, this book provides a world-wide perspective on the potential impact of nutrigenomics on our association with food. *Explores the rapidly developing, yet not fully understood, impact of nutrigenomics on the relationship to food medicalization, genetic privacy, nutrition and health. *Provides ground for further exploration to identify issues and provide analysis to aid in policy and regulation development *Provides ethical and legal insights into this unfolding science, as well as serving as a model for thinking about issues arising in other fields of science and technology

Genomics and Public Health

Author : Bartha Maria Knoppers
Publisher : Martinus Nijhoff Publishers
ISBN 13 : 9004155597
Total Pages : 342 pages
Book Rating : 4.0/5 (41 download)

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Book Synopsis Genomics and Public Health by : Bartha Maria Knoppers

Download or read book Genomics and Public Health written by Bartha Maria Knoppers and published by Martinus Nijhoff Publishers. This book was released on 2007 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: When genomics and public health are integrated into society, it will create as many responsibilities as rights for citizens, researchers, and decision makers. Indeed, the expression of genetic risk factors in both common and infectious diseases is of great interest to public health. Policy development in this area then needs to tackle crucial themes such as: research and its application to public health and genomic medicine, the authority of the state, the right to privacy, and the roles and responsibilities of citizens and the State. Considering the current fears of a world-wide pandemic, this book is a timely and insightful exploration of both research possibilities and the role of the state. It will help to understand the limits of possible state access to biobanks and data. It examines the issue of the possible use of newborn screening programmes by public health authorities. It also attempts to understand the protection of individual privacy and the public interest in the promotion of health and the prevention of disease. Moreover, do citizens have a say? Will public attitudes be different towards research in public health genomics compared to genetic testing?