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Author : Amit Alexander
Publisher : Springer Nature
ISBN 13 : 9819728592
Total Pages : 398 pages
Book Rating : 4.8/5 (197 download)
Download or read book Application of Nanocarriers in Brain Delivery of Therapeutics written by Amit Alexander and published by Springer Nature. This book was released on with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Josimar O. Eloy
Publisher : Springer Nature
ISBN 13 : 3030633896
Total Pages : 347 pages
Book Rating : 4.0/5 (36 download)
Download or read book Nanocarriers for Drug Delivery written by Josimar O. Eloy and published by Springer Nature. This book was released on 2021 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers basic aspects of different nanoparticles, including type of materials, lipid, polymeric and inorganic structures, synthesis strategies, as well as the main physicochemical characterization techniques. Moreover, this book addresses applications for both treatment and diagnosis of diseases, highlighting in vitro and in vivo findings and clinical evaluation. The chapters highlight the main barriers for drug delivery which can benefit from nanoencapsulation: the topical and oral routes. The main innovations in the field, such as gene therapy and functionalization of nanoparticles with a variety of moieties, including monoclonal antibodies for selective delivery, are discussed and illustrated with examples. Finally, the application of nanoparticles for drug delivery to cancer is reviewed considering toxicology and regulatory aspects.
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
ISBN 13 : 0128166290
Total Pages : 581 pages
Book Rating : 4.1/5 (281 download)
Download or read book Nanomaterials for Drug Delivery and Therapy written by Alexandru Mihai Grumezescu and published by William Andrew. This book was released on 2019-03-14 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomaterials for Drug Delivery and Therapy presents recent advances in the field of nanobiomaterials and their important applications in drug delivery, therapy and engineering. The book offers pharmaceutical perspectives, exploring the development of nanobiomaterials and their interaction with the human body. Chapters show how nanomaterials are used in treatments, including neurology, dentistry and cancer therapy. Authored by a range of contributors from global institutions, this book offers a broad, international perspective on how nanotechnology-based advances are leading to novel drug delivery and treatment solutions. It is a valuable research resource that will help both practicing medics and researchers in pharmaceutical science and nanomedicine learn more on how nanotechnology is improving treatments. - Assesses the opportunities and challenges of nanotechnology-based drug delivery systems - Explores how nanotechnology is being used to create more efficient drug delivery systems - Discusses which nanomaterials make the best drug carriers
Author : Chandrakantsing Pardeshi
Publisher : Academic Press
ISBN 13 : 0128225238
Total Pages : 556 pages
Book Rating : 4.1/5 (282 download)
Download or read book Direct Nose-to-Brain Drug Delivery written by Chandrakantsing Pardeshi and published by Academic Press. This book was released on 2021-06-16 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Direct Nose-to-Brain Drug Delivery provides the reader with precise knowledge about the strategies and approaches for enhanced nose-to-brain drug delivery. It highlights the development of novel nanocarrier-based drug delivery systems for targeted drug delivery to the brain microenvironments with a focus on the technological advances in the development of the novel drug delivery devices for intranasal administration, including special emphasis on brain targeting through nose. This book explores the various quantification parameters to assess the brain targeting efficiency following intranasal administration and includes an overview on the toxicity aspects of the various materials used to develop the direct nose-to-brain drug delivery vehicles and of the regulatory aspects including patents and current clinical status of the potential neurotherapeutics for the effective management of neuro-ailments. Technological advances in new drug delivery systems with diverse applications in pharmaceutical, biomedical, biomaterials, and biotechnological fields are also explained. This book is a crucial source that will assist the veteran scientists, industrial technologists, and clinical research professionals to develop new drug delivery systems and novel drug administration devices for the treatment of neuro-ailments. Explains the targeting approaches for enhanced brain targeting following intranasal drug administration Explores the various nanocarriers developed to date for neurotherapeutic delivery via nose-to-brain Discusses pharmaceutical and biomedical applications after nose-to-brain delivery of therapeutic pharmaceuticals and biologicals
Author : Raj K. Keservani
Publisher : CRC Press
ISBN 13 : 0429877536
Total Pages : 567 pages
Book Rating : 4.4/5 (298 download)
Download or read book Nanocarriers for Brain Targeting written by Raj K. Keservani and published by CRC Press. This book was released on 2019-08-05 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume, Nanocarriers for Brain Targeting: Principles and Applications, covers recent research on brain physiology and the development of drug delivery systems. It explores a diverse variety of strategies that can be employed to achieve drug targeting to the brain. The nanocarriers that are discussed include nanoparticles, vesicular carriers, carriers having carbon as a core constituent, dispersed systems, and more. The inherent anatomy and physiology of the brain renders it different from other organs. The past few decades have witnessed significant research on brain ailments in response to a majority of hospitalizations that occur due to age-related central nervous system disorders. The prevalence of diverse diseases such as Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, multiple sclerosis, HIV-dementia, etc., affect about 1.5 billion people globally, which is further anticipated to reach 1.9 billion by the year 2020. Nanocarriers for drug delivery to the brain are seen as one of the answers to this growing problem.
Author : Hugh Davson
Publisher : CRC Press
ISBN 13 : 9780849344725
Total Pages : 832 pages
Book Rating : 4.3/5 (447 download)
Download or read book Physiology of the CSF and Blood-Brain Barriers written by Hugh Davson and published by CRC Press. This book was released on 1995-11-27 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text/reference uses 574 figures and illustrations to help explain the relationships between blood and the cerebrospinal fluid (CSF) and central nervous system (CNS). The authors focus on the interaction of these fluids and the relative importance of the transport mechanisms of hormones from blood to nervous tissue. Carrier-mediated transport of many neuroactive peptides is discussed. Special aspects of the blood-brain barrier are covered in detail. An entire chapter is devoted to the comparative physiology of the CSF and the brain barriers. Physiologists in all fields will have an interest in the updated theories covered in this book.
Author : Prashant Kesharwani
Publisher : Academic Press
ISBN 13 : 0128122498
Total Pages : 480 pages
Book Rating : 4.1/5 (281 download)
Download or read book Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors written by Prashant Kesharwani and published by Academic Press. This book was released on 2018-04-20 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain anatomy and tumors and the progress and challenges in delivering drugs across the blood brain barrier. Several chapters are devoted to the latest technologies and advances in nanotechnology, along with practical solutions on how to design more effective nanocarriers for drug and gene delivery. This valuable resource prepares readers to develop novel drug delivery systems for the treatment of brain tumors that further promote the latest nanomedical technologies. - Addresses the progress and challenges inherent in delivering drugs across the blood brain barrier and offers strategies to maximize effectiveness - Draws upon the experience and expertise of international scientists working in the fields of drug delivery and nanomedicine - Considers the future possibilities of nanotechnology for delivering nanocarriers that better diagnose and treat brain tumors
Author : Gert Fricker
Publisher : Springer
ISBN 13 : 3662437872
Total Pages : 169 pages
Book Rating : 4.6/5 (624 download)
Download or read book The Blood Brain Barrier (BBB) written by Gert Fricker and published by Springer. This book was released on 2014-10-24 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
Author : Carla Vitorino
Publisher : CRC Press
ISBN 13 : 1000245594
Total Pages : 518 pages
Book Rating : 4.0/5 (2 download)
Download or read book Nanoparticles for Brain Drug Delivery written by Carla Vitorino and published by CRC Press. This book was released on 2021-03-15 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: In an era wherein nanotechnology has sparked a huge research interest, brain drug delivery is not an exception. Aiming at fighting several central nervous system (CNS) conditions, tailored nanoparticles open new avenues to address several challenges in the fields of drug delivery and brain targeting. This book gathers contributions from experts in different, complementary fields, having in common their interest in developing new strategies for brain delivery based on nanotechnologies. The book encompasses general aspects pertaining to fundamental development, including tripartite in silico–in vitro–in vivo approaches. It also covers a diversity of nanomedicines applied in treatment and/or diagnosis and monitoring of CNS disorders. Aspects concerning their translation from the bench to clinical practice are also seamlessly discussed. This book will inspire readers to discover possible approaches to holistically delivering drugs into the brain. Edited by Carla Vitorino, Andreia Jorge and Alberto Pais, this book will appeal to anyone involved in nanomedicine, pharmaceutics, neurological and cancer therapies, drug delivery research and computational and regulatory sciences.
Author : Anurag Kumar Singh
Publisher : CRC Press
ISBN 13 : 1003851843
Total Pages : 381 pages
Book Rating : 4.0/5 (38 download)
Download or read book Nanoarchitectonics for Brain Drug Delivery written by Anurag Kumar Singh and published by CRC Press. This book was released on 2024-02-22 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders. Features: Includes an overview of brain diseases and highlights the need for novel drug-delivery approaches Focuses on theoretical aspects of advanced drug-delivery systems for brain diseases including challenges and progress in nose-to-brain delivery Provides an overview of technological approaches and their implications for neurodegenerative disorders, central nervous system (CNS), and brain drug delivery in brain cancer Discusses key advances in the development of polymer nanoparticles for drug delivery to the CNS Reviews the role of herbal medicines and naturally derived polymeric nanoparticle for the treatment of neurodegenerative disorders This book is aimed at graduate students and researchers in biomedical engineering, biotechnology, drug delivery, and neurology.
Author : Yasemin Gürsoy Özdemir
Publisher : Academic Press
ISBN 13 : 9780128037966
Total Pages : 0 pages
Book Rating : 4.0/5 (379 download)
Download or read book Nanotechnology Methods for Neurological Diseases and Brain Tumors written by Yasemin Gürsoy Özdemir and published by Academic Press. This book was released on 2017-07-17 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology Methods for Neurological Diseases and Brain Tumors: Drug Delivery across the Blood-Brain Barrier compiles the latest (and future potential) treatment strategies for brain tumors and neurological diseases, in particular Alzheimer's, Parkinson's and stroke, those that bypass the blood/brain barrier. The current understanding of brain drug delivery and access is discussed in Chapter One, with the next section focusing on the implementation of the nose-to-brain intranasal route in brain-targeted drug delivery. In addition, nanotechnology-based brain drug delivery is covered in Chapter Three. This avenue offers impressive improvement in the treatment of neurological diseases and brain tumors by using bio-engineered systems that interact with biological systems at a molecular level. In Chapter Four, emphasis is placed on the need for brain-targeted experimental models that mimic disease conditions. Final chapters discuss the very latest advances in targeted treatment strategies for neurological diseases and brain tumors.
Author : Yashwant V Pathak
Publisher : Springer
ISBN 13 : 3030061159
Total Pages : 499 pages
Book Rating : 4.0/5 (3 download)
Download or read book Surface Modification of Nanoparticles for Targeted Drug Delivery written by Yashwant V Pathak and published by Springer. This book was released on 2019-03-11 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.
Author : Vivek Dave
Publisher : John Wiley & Sons
ISBN 13 : 1119711681
Total Pages : 467 pages
Book Rating : 4.1/5 (197 download)
Download or read book Nanopharmaceutical Advanced Delivery Systems written by Vivek Dave and published by John Wiley & Sons. This book was released on 2020-12-29 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.
Author : Vinod Kumar Yata
Publisher : Springer Nature
ISBN 13 : 3030471209
Total Pages : 340 pages
Book Rating : 4.0/5 (34 download)
Download or read book Nanopharmaceuticals: Principles and Applications Vol. 3 written by Vinod Kumar Yata and published by Springer Nature. This book was released on 2020-08-19 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the third volume on this subject and focuses on the recent advances of nanopharmaceuticals in cancer, dental, dermal and drug delivery applications and presents their safety, toxicity and therapeutic efficacy. The book also includes the transport phenomenon of nanomaterials and important pathways for drug delivery applications. It goes on to explain the toxicity of nanoparticles to different physiological systems and methods used to assess this for different organ systems using examples of in vivo systems.
Author : Arnold B. Etame
Publisher :
ISBN 13 : 9780494794470
Total Pages : pages
Book Rating : 4.7/5 (944 download)
Download or read book Enhanced Delivery of Gold Nanoparticles with Therapeutic Potential for Targeting Human Brain Tumors written by Arnold B. Etame and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : V. P. Torchilin
Publisher : Imperial College Press
ISBN 13 : 186094907X
Total Pages : 758 pages
Book Rating : 4.8/5 (69 download)
Download or read book Nanoparticulates as Drug Carriers written by V. P. Torchilin and published by Imperial College Press. This book was released on 2006 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by key experts in the field of nanomedicine, this book provides a broad introduction to the important field of nanomedicine and application of nanotechnology for drug delivery. It covers up-to-date information regarding various nanoparticulate drug delivery systems, describes the various opportunities for the application of nanoparticular drug carriers in different areas of clinical medicine, and analyzes already available information on their clinical applications. This book can be used as an advanced textbook by graduate students and young scientists and clinicians at the early stages of their career. It is also suitable for non-experts from related areas of chemistry, biochemistry, molecular biology, biomedical engineering, physiology, experimental and clinical medicine, and pharmaceutical sciences, who are interested in general problems of drug delivery and drug targeting, as well as in more specialized topics of using nanoparticulate-mediated drug delivery approaches in the individual areas of clinical medicine. Prof Torchilin is an expert in Nanomedicine and a recipient of numerous awards including the Lenin Prize in Science & Technology of the former USSR, membership in the European Academy of Sciences, and AAPS Research Achievement Award in Pharmaceutics and Drug Delivery. He served as an Associate Professor of Radiology at Harvard Medical School before joining Northeastern University as the Chairman of the Department of Pharmaceutical Sciences. Sample Chapter(s). Chapter 1: Introduction. Nanocarriers for Drug Delivery: Needs and Requirements (442 KB). Contents: Nanoparticle Flow: Implications for Drug Delivery (A T Florence); Polymer Micelles as Drug Carriers (E V Batrakova et al.); Lipoproteins as Pharmaceutical Carriers (S Liu et al.); Dendrimers as Nanoparticular Drug Carriers (S Svenson & D A Tomalia); Cells and Cell Ghosts as Drug Carriers (J M Lanao & M L Sayalero); Magnetic Nanoparticles as Drug Carriers (U O Hnfeli & M Chastellain); Liposomal Drug Carriers in Cancer Therapy (A A Gabizon); Delivery of Nanoparticles to the Cardiovascular System (B-A Khaw); Nanoparticles for Targeting Lymphatics (W Phillips); Nanoparticular Carriers for Ocular Drug Delivery (A Sanchez & M J Alonso); and other papers. Readership: Graduate students, academics in nanomedicine, clinicians, pharmacologists, pharmacists, bioengineers, researchers in biotechnology and diagnostic imaging."
Author : Bingyang Shi
Publisher : Frontiers Media SA
ISBN 13 : 2832551858
Total Pages : 84 pages
Book Rating : 4.8/5 (325 download)
Download or read book Application For Nanotechnology For the Treatment of Brain Diseases and Disorders written by Bingyang Shi and published by Frontiers Media SA. This book was released on 2024-07-15 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain diseases and disorders, such as dementia and glioblastoma, are among the deadliest diseases in humans, and put an overwhelming burden on healthcare systems. Despite recent progress in elucidating the causes of brain diseases, a limited amount of effective therapeutics have been developed. One major obstacle is the efficient delivery of therapeutic agents across the Blood-Brain Barrier (BBB) into the affected region of the brain. Utilizing nanoparticles as a drug delivery system provides a simple and effective approach, with improved efficacy and bioavailability. In the last two decades, numerous advances have been made in this field, which will bring nanomedicine closer to the clinic and bring new therapeutic options for the treatment of brain diseases which have proved challenging to treat. Such advancements include improvements in the novel design of nanoparticles with tissue compatibility, versatile loading capacity, BBB penetration ability and greater target specificity.
