Author : Rachel Bierbrier
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (135 download)
Book Synopsis An Investigation Into the Acneiform Eruption Induced by Epidermal Growth Factor Receptor Inhibitors by : Rachel Bierbrier
Download or read book An Investigation Into the Acneiform Eruption Induced by Epidermal Growth Factor Receptor Inhibitors written by Rachel Bierbrier and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The use of targeted therapy against epidermal growth factor receptors, a tyrosine kinase receptor, has come to the forefront for many cancers including lung cancer, head and neck cancers and gastrointestinal malignancy. Although these agents are associated with a lower incidence of systemic side effects, there is a higher frequency of mucocutaneous side effects, specifically an acneiform eruption. Little is known about patient risk factors for the development of severe acneiform eruptions. Given that the onset of the eruption is soon after initiating EGFR therapy, identifying high risk groups and starting prophylactic therapy early on may prevent severe cutaneous adverse reactions. Chapter one is an investigation into risk factors for the development of acneiform eruptions in a cohort of non-small cell lung cancer patients in Montreal, Canada. Effective management of cutaneous adverse events can improve patient outcomes and prevent cancer therapy discontinuation. There is data demonstrating different strategies used by oncologists and dermatologists for management of the acneiform eruptions. However, little is known regarding the Canadian landscape on management of the eruption between specialties. Chapter two is a cross sectional investigation into the management strategies of acneiform eruptions by dermatologists and oncologists across Canada. Currently, the preferred systemic therapy for management of acneiform eruptions in guidelines are tetracycline antibiotics, with little data on alternative therapeutic options. Therefore, the objective of Chapter three is to explore the current literature on the management of the acneiform eruption using systemic retinoids"--