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Aging And Health A Systems Biology Perspective
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Book Synopsis Aging and Health - A Systems Biology Perspective by : A.I. Yashin
Download or read book Aging and Health - A Systems Biology Perspective written by A.I. Yashin and published by Karger Medical and Scientific Publishers. This book was released on 2014-10-09 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging is a major risk factor for chronic diseases, which in turn can provide information about the aging of a biological system. This publication serves as an introduction to systems biology and its application to biological aging. Key pathways and processes that impinge on aging are reviewed, and how they contribute to health and disease during aging is discussed. The evolution of this situation is analyzed, and the consequences for the study of genetic effects on aging are presented. Epigenetic programming of aging, as a continuation of development, creates an interface between the genome and the environment. New research into the gut microbiome describes how this interface may operate in practice with marked consequences for a variety of disorders. This analysis is bolstered by a view of the aging organism as a whole, with conclusions about the mechanisms underlying resilience of the organism to change, and is expanded with a discussion of circadian rhythms in aging. Finally, the book presents an outlook for the development of interventions to delay or to reverse the features of aging. The publication is recommended to students, researchers as well as professionals dealing with public health and public policy related to an aging society.
Book Synopsis Biochemistry and Cell Biology of Ageing: Part II Clinical Science by : J. Robin Harris
Download or read book Biochemistry and Cell Biology of Ageing: Part II Clinical Science written by J. Robin Harris and published by Springer. This book was released on 2019-03-19 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the subcellular Biochemistry series will attempt to bridge the gap between the subcellular events that are related to aging as they were described in the first volume of this set of two books and the reality of aging as this is seen in clinical practice. All chapters will start from the biochemistry or cell biology, where the data is available and work up towards the understanding that we have of aging in the various areas that are related to the subject. Key focus points for this volume are nutrition, external factors and genetics on aging. There will also be chapters that will focus on various organs or tissues in which aging has been well studied, like the eyes, the muscles, the immune system and the bones. The aim of the book project and the book project that is published in concert with this volume is to bring the subcellular and clinical areas into closer contact.
Book Synopsis Explaining Health Across the Sciences by : Jonathan Sholl
Download or read book Explaining Health Across the Sciences written by Jonathan Sholl and published by Springer Nature. This book was released on 2020-08-28 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume aims to better understand the multifaceted phenomenon we call health. Going beyond simple views of health as the absence of disease or as complete well-being, this book unites scientists and philosophers. The contributions clarify the links between health and adaptation, robustness, resilience, or dynamic homeostasis, and discuss how to achieve health and healthy aging through practices such as hormesis. The book is divided into three parts and a conclusion: the first part explains health from within specific disciplines, the second part explores health from the perspective of a bodily part, system, function, or even the environment in which organisms live, and the final part looks at more clinical or practical perspectives. It thereby gathers, across 30 chapters, diverse perspectives from the broad fields of evolutionary and systems biology, immunology, and biogerontology, more specific areas such as odontology, cardiology, neurology, and public health, as well as philosophical reflections on mental health, sexuality, authenticity and medical theories. The overarching aim is to inform, inspire and encourage intellectuals from various disciplines to assess whether explanations in these disparate fields and across biological levels can be sufficiently systematized and unified to clarify the complexity of health. It will be particularly useful for medical graduates, philosophy graduates and research professionals in the life sciences and general medicine, as well as for upper-level graduate philosophy of science students.
Book Synopsis Health, Illness, and Optimal Aging by : Carolyn M. Aldwin
Download or read book Health, Illness, and Optimal Aging written by Carolyn M. Aldwin and published by SAGE. This book was released on 2004 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors undertake the difficult task of assembling an objective and holistic picture of human aging, including the physical aspects of aging, chronic disease and health promotion in the later years, for students and professionals.
Download or read book Biology of Aging written by Robert Arking and published by Oxford University Press. This book was released on 2006-02-02 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Robert Arking's Biology of Aging, 3rd edition, is an introductory text to the biology of aging which gives advanced undergraduate and graduate students a thorough review of the entire field. His prior two editions have also served admirably as a reference text for clinicians and scientists. This new edition captures the extraordinary recent advances in our knowledge of the ultimate and proximal mechanisms underlying the phenomenon of aging. As a result, six important conceptual changes are included here: ? Clarified distinctions between the biological mechanisms involved in longevity determination and those involved in senescent processes. ? A new conceptual framework around which we can organize all the new facts about aging. This will assist readers to make sense of the information and use the data to form their own ideas. ? Increased knowledge of aging cells has lead to new ideas on how a cell transits from a healthy state to a senescent state, while still allowing for high levels of intra- and inter-specific variability. ? Discussion of senescent mechanisms assists the reader to understand that aging is a non-programmatic loss of function, likely arising from the loss of regulatory signals, and so is modifiable in the laboratory. ? Because the standard evolutionary story does not fully explain the evolution of social organisms, this edition also includes recent work dealing with intergenerational resource transfers. ? Lastly, if aging mechanisms are plastic, then the demand to move these anti-aging interventions into the human arena will inevitably grow. A discussion of the biological and ethical arguments on both sides of the question frames the question in an appropriate manner. The mass of data related to aging is summarized into fifteen focused chapters, each dealing with some particular aspect of the problem. The last two chapters integrate all this material into a coherent view of how the relevant biological processes change over the life span. This view is expressed in two non-technical figures (you might say that the whole book exists to fully support Figs 9-4 & 14-9), whose meanings are elucidated as the reader progresses through the book.
Download or read book Human Aging written by Calogero Caruso and published by Academic Press. This book was released on 2021-05-11 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive picture of all the biological aspects of human aging by describing the key mechanisms associated with human aging and covering events that could disrupt the normal course of aging. Each chapter includes a summary of the salient points covered, along with futures prospects. The book provides readers with the information they need to gain or deepen the skills needed to evaluate the mechanisms of aging and age-related diseases and to monitor the effectiveness of therapies aimed at slowing aging. The book encourages PhD and Postdoc students, researchers, health professionals and others interested in the biology of aging to explore the fascinating and challenging questions about why and how we age as well as what can and cannot be done about it. Concentrates on different processes, e.g., oxidative stress, cellular senescence and Inflammaging Offers the ability to access cross-sectional knowledge more easily Written by expert researchers in biogerontology who are actively involved in various fields within aging research
Book Synopsis Successful Aging by : John Wallis Rowe
Download or read book Successful Aging written by John Wallis Rowe and published by Random House Large Print Publishing. This book was released on 1998 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the results of the MacArthur Foundation Study of Aging in America, which show how to maintain optimum physical and mental strength throughout later life.
Book Synopsis Health, Illness, and Optimal Aging by : Carolyn M. Aldwin
Download or read book Health, Illness, and Optimal Aging written by Carolyn M. Aldwin and published by SAGE Publications. This book was released on 2003-07-17 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Health, Illness, and Optimal Aging: Biological and Psychosocial Perspectives, Carolyn M. Aldwin and Diane F. Gilmer undertake the challenging task of assembling an objective and holistic picture of human aging. The authors provide comprehensive, multidisciplinary coverage of the physical aspects of aging, including age-related changes and disease-related processes, the demography of the aging population, theories of aging, and the promotion of optimal aging. In addition, the book covers the psychosocial aspects of aging, including mental health, stress and coping, spirituality, and care giving in later years. Health, Illness and Optimal Aging is recommended for researchers seeking an overview of health psychology and aging, as well as undergraduate and graduate students taking classes in the social, behavioral, and health sciences. This text is also valuable for practitioners working with the elderly in fields such as nursing, social work, occupational and physical therapy, day-care and nursing home administration, psychology, and rehabilitation.
Book Synopsis Oxford Textbook of Old Age Psychiatry by : Tom Dening
Download or read book Oxford Textbook of Old Age Psychiatry written by Tom Dening and published by Oxford University Press, USA. This book was released on 2020-11-05 with total page 961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the authoritative Oxford Textbooks in Psychiatry series, Oxford Textbook of Old Age Psychiatry, Third Edition has been thoroughly updated to reflect the developments in old age psychiatry since publication of the Second Edition in 2013, and remains an essential reference for anyone interested in the mental health care of older people.
Book Synopsis Computational Systems Biology by : Andres Kriete
Download or read book Computational Systems Biology written by Andres Kriete and published by Elsevier Inc. Chapters. This book was released on 2013-11-26 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: What makes the study of aging particularly challenging is the wide spectrum of phenotypical changes that can be observed during its progression. While initial attention was paid to damage accumulation, dysfunction, and failure, it is now realized that aging, and associated diseases including dementias, are influenced by a multitude of interacting factors. Proximal mechanisms beyond passive accumulation of damage include regulatory mechanisms, stress responses, changes in networks, as well as genetic and stochastic effects. The application of computational systems biology in aging, which is in line with other attempts to overcome the study of isolated or compartmentalized mechanisms, has made initial progress allowing us to simulate partial aspects of the aging dynamics and to make new hypotheses about how these aging mechanism shape disease progression. Here we provide examples for analysis of networks, regulatory mechanisms, and spatiotemporal effects in the study of proximal mechanisms of aging and Parkinson’s Disease. In addition, we introduce complexity theories that may contribute to explain the ultimate causes of aging with an evolutionary view.
Book Synopsis Health, Illness, and Optimal Aging, Second Edition by : Carolyn M. Aldwin
Download or read book Health, Illness, and Optimal Aging, Second Edition written by Carolyn M. Aldwin and published by Springer Publishing Company. This book was released on 2013-01-17 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Print+CourseSmart
Book Synopsis The Gerontological Imagination by : Kenneth F. Ferraro
Download or read book The Gerontological Imagination written by Kenneth F. Ferraro and published by Oxford University Press. This book was released on 2018 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: The power of the gerontological imagination -- Causality -- Life course analysis -- Multifaceted change -- Heterogeneity -- Accumulation process -- Ageism -- The gerontological imagination at work in scientific communities
Book Synopsis A Life Course Approach to Healthy Ageing by : Diana Kuh
Download or read book A Life Course Approach to Healthy Ageing written by Diana Kuh and published by OUP Oxford. This book was released on 2013-12-19 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Healthy ageing has long been a neglected area of epidemiological research as the traditional focus has been on specific chronic diseases of older life. There is a growing consensus from scientists, research funders and policy makers that ageing itself needs to be studied from an interdisciplinary and life course perspective, to inform strategies for reducing the societal and individual costs of an ageing population. A Life Course Approach to Healthy Ageing is a synthesis of life course perspectives in epidemiology and interdisciplinary perspectives in ageing research. It brings together expert investigators of maturing birth cohort and ageing studies, cross-cutting methodologists, and authorities in ageing research and knowledge transfer from across the world in one wide-ranging volume. Contributors discuss how aspects of healthy ageing are conceptualised, defined and measured; relate to each other; change across life; and are influenced by biological, psychological and social factors operating from early life onwards. They identify research gaps, and suggest how evidence from observational studies can be strengthened through improved study design and longitudinal analysis, thereby increasing the research contribution to practice or policy change. The book considers how we might delay or slow down the progressive, generalised impairment of function that occurs at the individual, body system and cellular levels, as people grow older. It also considers the determinants of wellbeing in older people, including personal fulfilment, positive emotions and social relationships. Broad in scope, discussing topics from genetics to psychological and social wellbeing, A Life Course Approach to Healthy Ageing is a key resource for epidemiologists, social scientists, clinicians, public health physicians, policy makers and practitioners with a research interest in healthy ageing.
Book Synopsis Aging, Social Change by : James G. March
Download or read book Aging, Social Change written by James G. March and published by . This book was released on 1981 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scholars from social and behavioral sciences pose researchable questions and testable hypotheses regarding older people from the perspective of data and theory in their own disciplines. They discuss public policy and aging; the impact of business, government and social institutions on the elderly; and the personal resources and living conditions of the old.
Book Synopsis Psychology of Aging by : Brian Yochim, PhD, ABPP
Download or read book Psychology of Aging written by Brian Yochim, PhD, ABPP and published by Springer Publishing Company. This book was released on 2017-12-28 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The book goes well beyond the information in undergraduate texts and provides stimulating and useful coverage of key topics in biopsychosocial aging. Psychology is not prepared for the future growth of our older adult population, and I suggest Psychology of Aging: A Biopsychosocial Perspective as required reading for students" --William E. Haley, PhD; Professor; School of Aging Studies; College of Behavioral and Community Sciences, Tampa, FL "This book distinguishes itself from previous publications on the topic with a thorough review of the history profession of geropsychology and its timely inclusion of chapters on brain imaging techniques and the aging brain, cultural differences in aging ethnic and sexual minorities, cognitive interventions, and more. This book is a must read for undergraduate and graduate students studying aging, and one I will definitely recommend to students new to the area."--Sherry A. Beaudreau, Ph.D., ABPP, VA Palo Alto Health Care System and Stanford University School of Medicine "Brian Yochim and Erin Woodhead have created an invaluable tool for learning about and teaching geropsychology...This book will serve as a seminal text in training psychologists, social workers, and many other disciplines in the psychology of aging." --Erin E. Emery-Tiburcio, Ph.D., ABPP, Rush University, Chicago, IL The only graduate text to encompass the full range of issues regarding the psychology of aging This is the first graduate-level text that offers a comprehensive, in-depth chronicle of issues surrounding the psychology of aging emphasizing psychology, with a foundation in the biology, and an expansion into the sociological aspects of aging. The text is divided into three sections: biological underpinnings of aging, psychological components of aging, and social aspects of aging. Among the multitude of topics addressed are biological theories of aging, neuroimaging methods in aging research, neuroplasticity, cognitive reserve and cognitive interventions, a detailed overview of neurocognitive disorders in aging such as Alzheimer's disease and Lewy body disease, relationships in aging, work vs. retirement, cultural issues in aging, and aging and the legal system, to name just a few critical topics. With an emphasis on promoting critical thinking, the text is enriched with discussion questions in each chapter along with suggestions for more in-depth readings. In addition it includes chapter PowerPoints and an Instructor’s Manual with sample syllabi for a 10-week course and a 15-week course. Written for graduate students in multiple gerontology-related disciplines, the text is also of value to individuals studying nursing, medicine, social work, biology, and occupational, physical, and speech therapies. Key Features: Addresses the biological underpinnings of aging, psychological components, and social aspects Written by a variety of experts on each area Emphasizes critical thinking throughout the text Presents discussion questions in each chapter Includes PowerPoints and an Instructor’s Manual with sample syllabi Tailored to graduate students from multiple disciplines embarking on clinical or research careers involving older adults.
Download or read book Lifespan written by David A. Sinclair and published by Atria Books. This book was released on 2019-09-10 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.” —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.
Book Synopsis Human Aging by : Augustine Gaspar DiGiovanna
Download or read book Human Aging written by Augustine Gaspar DiGiovanna and published by McGraw-Hill Companies. This book was released on 1994 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides comprehensive coverage of biological aspects of human ageing at a level accessible to students with little or no science background. It is aimed at students pursuing a career working with, or for, the elderly. Each system is covered in its own chapter. Individual chapters present the structure and function of each body system, followed by natural age changes, and conclude with abnormal changes or diseased conditions of the elderly. Homeostasis is a unifying theme throughout the text: systems are presented relative to the body's ability to maintain homeostasis and good health is the main theme.
