Affective Computing and Interaction: Psychological, Cognitive and Neuroscientific Perspectives

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Publisher : IGI Global
ISBN 13 : 1616928948
Total Pages : 458 pages
Book Rating : 4.6/5 (169 download)

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Book Synopsis Affective Computing and Interaction: Psychological, Cognitive and Neuroscientific Perspectives by : G”k‡ay, Didem

Download or read book Affective Computing and Interaction: Psychological, Cognitive and Neuroscientific Perspectives written by G”k‡ay, Didem and published by IGI Global. This book was released on 2010-10-31 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since interactions may occur between animals, humans, or computational agents, an interdisciplinary approach which investigates foundations of affective communication in a variety of platforms is indispensable. In the field of affective computing, a collection of research, merging decades of research on emotions in psychology, cognition and neuroscience will inspire creative future research projects and contribute to the prosperity of this emerging field. Affective Computing and Interaction: Psychological, Cognitive and Neuroscientific Perspectives examines the current state and the future prospects of affect in computing within the context of interactions. Uniting several aspects of affective interactions and topics in affective computing, this reference reviews basic foundations of emotions, furthers an understanding of the contribution of affect to our lives and concludes by revealing current trends and promising technologies for reducing the emotional gap between humans and machines, all within the context of interactions.

Affective Computing and Interaction

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ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (986 download)

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Book Synopsis Affective Computing and Interaction by : Didem Gökçay

Download or read book Affective Computing and Interaction written by Didem Gökçay and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Uniting several aspects of affective interactions and topics in affective computing, this reference reviews basic foundations of emotions, furthers an understanding of the contribution of affect to our lives and concludes by revealing current trends and promising technologies for reducing the emotional gap between humans and machines, all within the context of interactions"--.

A Blueprint for Affective Computing

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Publisher : Oxford University Press
ISBN 13 : 0199566704
Total Pages : 408 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis A Blueprint for Affective Computing by : Klaus R. Scherer

Download or read book A Blueprint for Affective Computing written by Klaus R. Scherer and published by Oxford University Press. This book was released on 2010-09-23 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Affective computing' is a branch of computing concerned with the theory and construction of machines which can detect, respond to, and simulate human emotional states. This book presents an interdisciplinary exploration of this rapidly expanding field, aimed at those in psychology, computational neuroscience, computer science, and AI.

The Oxford Handbook of Affective Computing

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Publisher : Oxford Library of Psychology
ISBN 13 : 0199942234
Total Pages : 625 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis The Oxford Handbook of Affective Computing by : Rafael A. Calvo

Download or read book The Oxford Handbook of Affective Computing written by Rafael A. Calvo and published by Oxford Library of Psychology. This book was released on 2015 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Oxford Handbook of Affective Computing is a definitive reference in the burgeoning field of affective computing (AC), a multidisciplinary field encompassing computer science, engineering, psychology, education, neuroscience, and other disciplines. AC research explores how affective factors influence interactions between humans and technology, how affect sensing and affect generation techniques can inform our understanding of human affect, and on the design, implementation, and evaluation of systems involving affect at their core. The volume features 41 chapters and is divided into five sections: history and theory, detection, generation, methodologies, and applications. Section 1 begins with the making of AC and a historical review of the science of emotion. The following chapters discuss the theoretical underpinnings of AC from an interdisciplinary viewpoint. Section 2 examines affect detection or recognition, a commonly investigated area. Section 3 focuses on aspects of affect generation, including the synthesis of emotion and its expression via facial features, speech, postures, and gestures. Cultural issues are also discussed. Section 4 focuses on methodological issues in AC research, including data collection techniques, multimodal affect databases, formats for the representation of emotion, crowdsourcing techniques, machine learning approaches, affect elicitation techniques, useful AC tools, and ethical issues. Finally, Section 5 highlights applications of AC in such domains as formal and informal learning, games, robotics, virtual reality, autism research, health care, cyberpsychology, music, deception, reflective writing, and cyberpsychology. This compendium will prove suitable for use as a textbook and serve as a valuable resource for everyone with an interest in AC."--

New Perspectives on Affect and Learning Technologies

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Publisher : Springer Science & Business Media
ISBN 13 : 1441996257
Total Pages : 284 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis New Perspectives on Affect and Learning Technologies by : Rafael A. Calvo

Download or read book New Perspectives on Affect and Learning Technologies written by Rafael A. Calvo and published by Springer Science & Business Media. This book was released on 2011-07-15 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph integrates theoretical perspectives on affect and learning with recent research in affective computing with an emphasis on building new learning technologies. The "new perspectives" come from the intersection of several research themes: -Basic research on emotion, cognition, and motivation applied to learning environments -Pedagogical and motivational strategies that are sensitive to affective and cognitive processes -Multimodal Human Computer Interfaces, with a focus on affect recognition and synthesis -Recent advances in affect-sensitive Intelligent Tutoring Systems -Novel methodologies to investigate affect and learning -Neuroscience research on emotions and learning

Cyberpsychology and the Brain

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Publisher : Cambridge University Press
ISBN 13 : 1107094879
Total Pages : 463 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Cyberpsychology and the Brain by : Thomas D. Parsons

Download or read book Cyberpsychology and the Brain written by Thomas D. Parsons and published by Cambridge University Press. This book was released on 2017-04-07 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book proposes a framework for integrating neuroscience and cyberpsychology for the study of social, cognitive, and affective processes.

Blueprint for Affective Computing

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (14 download)

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Book Synopsis Blueprint for Affective Computing by : Klaus R. Scherer

Download or read book Blueprint for Affective Computing written by Klaus R. Scherer and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "'Affective computing' is a branch of computing concerned with the theory and construction of machines which can detect, respond to, and simulate human emotional states. It is an interdisciplinary field spanning the computer sciences, psychology, and cognitive science. Affective computing is a rapidly developing field within industry and science. There is now a great drive to make technologies such as robotic systems, avatars in service-related human computer interaction, e-learning, game characters, or companion devices more marketable by endowing the 'soulless' robots or agents with the ability to recognize and adjust to the user's feelings as well as to be able to communicate appropriate emotional signals. A Blueprint for Affective Computing: A sourcebook and manual is the very first attempt to ground affective computing within the disciplines of psychology, affective neuroscience, and philosophy. This book illustrates the contributions of each of these disciplines to the development of the ever-growing field of affective computing. In addition, it demonstrates practical examples of cross-fertilization between disciplines in order to highlight the need for integration of computer science, engineering and the affective sciences. Focusing on a topic at the frontiers of human computer interaction research, this book will be of great interest to students and researchers in psychology, neuroscience, computational neuroscience, computer science, and artificial intelligence"--

Emotion-Oriented Systems

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Publisher : John Wiley & Sons
ISBN 13 : 111860332X
Total Pages : 338 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Emotion-Oriented Systems by : Catherine Pelachaud

Download or read book Emotion-Oriented Systems written by Catherine Pelachaud and published by John Wiley & Sons. This book was released on 2013-02-07 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Affective Computing domain, term coined by Rosalind Picard in 1997, gathers several scientific areas such as computer science, cognitive science, psychology, design and art. The humane-machine interaction systems are no longer solely fast and efficient. They aim to offer to users affective experiences: user’s affective state is detected and considered within the interaction; the system displays affective state; it can reason about their implication to achieve a task or resolve a problem. In this book, we have chosen to cover various domains of research in emotion-oriented systems. Our aim is also to highlight the importance to base the computational model on theoretical foundations and on natural data.

Affective Information Processing

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Publisher : Springer Science & Business Media
ISBN 13 : 1848003064
Total Pages : 347 pages
Book Rating : 4.8/5 (48 download)

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Book Synopsis Affective Information Processing by : Jianhua Tao

Download or read book Affective Information Processing written by Jianhua Tao and published by Springer Science & Business Media. This book was released on 2008-12-02 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Affective information processing assigns computers the human-like capabilities of observation, interpretation and generation of affect features. It is an important topic for harmonious human-computer interaction, by increasing the quality of human-computer communication and improving the intelligence of the computer. Discussing state of art of the research in affective information processing, this book summarises key technologies researched, such as facial expression recognition, face animation, emotional speech synthesis, intelligent agent, and virtual reality. The detailed discussion covers a wide range of topics including hot topics which look to challenge and improve current research work. Written to provide an opportunity for scientists, engineers and graduate students to learn problems, solutions and technologies in the topic area, this book will provide insight and prove a valuable reference tool.

Emotions and Affect in Human Factors and Human-Computer Interaction

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Publisher : Academic Press
ISBN 13 : 0128018798
Total Pages : 624 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Emotions and Affect in Human Factors and Human-Computer Interaction by : Myounghoon Jeon

Download or read book Emotions and Affect in Human Factors and Human-Computer Interaction written by Myounghoon Jeon and published by Academic Press. This book was released on 2017-05-17 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emotions and Affect in Human Factors and Human–Computer Interaction is a complete guide for conducting affect-related research and design projects in H/F and HCI domains. Introducing necessary concepts, methods, approaches, and applications, the book highlights how critical emotions and affect are to everyday life and interaction with cognitive artifacts. The text covers the basis of neural mechanisms of affective phenomena, as well as representative approaches to Affective Computing, Kansei Engineering, Hedonomics, and Emotional Design. The methodologies section includes affect induction techniques, measurement techniques, detection and recognition techniques, and regulation models and strategies. The application chapters discuss various H/F and HCI domains: product design, human–robot interaction, behavioral health and game design, and transportation. Engineers and designers can learn and apply psychological theories and mechanisms to account for their affect-related research and can develop their own domain-specific theory. The approach outlined in this handbook works to close the existing gap between the traditional affect research and the emerging field of affective design and affective computing. Provides a theoretical background of affective sciences Demonstrates diverse affect induction methods in actual research settings Describes sensing technologies, such as brain–computer interfaces, facial expression detection, and more Covers emotion modeling and its application to regulation processes Includes case studies and applied examples in a variety of H/F and HCI application areas Addresses emerging interdisciplinary areas including Positive Technology, Subliminal Perception, Physiological Computing, and Aesthetic Computing

Affect and Emotion in Human-Computer Interaction

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Publisher : Springer Science & Business Media
ISBN 13 : 3540850988
Total Pages : 250 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Affect and Emotion in Human-Computer Interaction by : Christian Peter

Download or read book Affect and Emotion in Human-Computer Interaction written by Christian Peter and published by Springer Science & Business Media. This book was released on 2008-08-25 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Affect and emotion play an important role in our everyday lives: They are present whatever we do, wherever we are, and wherever we go, without us being aware of them for much of the time. When it comes to interaction, be it with humans, technology, or humans via technology, we suddenly become more aware of emotion, either by seeing the other’s emotional expression, or by not getting an emotional response while anticipating one. Given this, it seems only sensible to explore affect and emotion in human-computer interaction, to investigate the underlying principles, to study the role they play, to develop methods to quantify them, and to finally build applications that make use of them. This is the research field for which, over ten years ago, Rosalind Picard coined the phrase "affective computing". The present book provides an account of the latest work on a variety of aspects related to affect and emotion in human-technology interaction. It covers theoretical issues, user experience and design aspects as well as sensing issues, and reports on a number of affective applications that have been developed in recent years.

Character Computing

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Publisher : Springer Nature
ISBN 13 : 303015954X
Total Pages : 173 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Character Computing by : Alia El Bolock

Download or read book Character Computing written by Alia El Bolock and published by Springer Nature. This book was released on 2020-01-01 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book gives an introduction into the theory and practice of the transdisciplinary field of Character Computing, introduced by Alia El Bolock. The latest scientific findings indicate that “One size DOES NOT fit all” in terms of how to design interactive systems and predict behavior to tailor the interaction experience. Emotions are one of the essential factors that influence people’s daily experiences; they influence decision making and how different emotions are interpreted by different individuals. For example, some people may perform better under stress and others may break. Building upon Rosalind Picard’s vision, if we want computers to be genuinely intelligent and to interact naturally with us, we must give computers the ability to recognize, understand, even to have and express emotions and how different characters perceive and react to these emotions, hence having richer and truly tailored interaction experiences. Psychological processes or personality traits are embedded in the existing fields of Affective and Personality Computing. However, this book is the first that systematically addresses this including the whole human character; namely our stable personality traits, our variable affective, cognitive and motivational states as well as our morals, beliefs and socio-cultural embedding. The book gives an introduction into the theory and practice of the transdisciplinary field of Character Computing. The emerging field leverages Computer Science and Psychology to extend technology to include the whole character of humans and thus paves the way for researchers to truly place humans at the center of any technological development. Character Computing is presented from three main perspectives: ● Profiling and sensing the character ● Leveraging characters to build ubiquitous character-aware systems ● Investigating how to extend Artificial Intelligence to create artificial characters

Affective Interactions

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Publisher : Springer
ISBN 13 : 3540445595
Total Pages : 236 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Affective Interactions by : Ana Paiva

Download or read book Affective Interactions written by Ana Paiva and published by Springer. This book was released on 2006-12-30 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Affective computing is a fascinating new area of research emerging in computer science. It dwells on problems where "computing is related to, arises from or deliberately influences emotions" (Picard 1997). Following this new research direction and considering the human element as crucial in designing and implementing interactive intelligent interfaces, affective computing is now influencing the way we shape, design, construct, and evaluate human-computer interaction and computer-mediated communcation. This book originates from a workshop devoted to affective interactions. It presents revised full versions of several papers accepted in preliminary version for the workshop and various selectively solicited papers by key people as well as an introductory survey by the volume editor and interview with Rosaling Picard, a pioneer researcher in the field. The book competently assesses the state of the art in this fascinating new field.

Emotion in Games

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Publisher : Springer
ISBN 13 : 3319413163
Total Pages : 338 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Emotion in Games by : Kostas Karpouzis

Download or read book Emotion in Games written by Kostas Karpouzis and published by Springer. This book was released on 2016-11-02 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: The core message of this book is: computer games best realise affective interaction. This book brings together contributions from specialists in affective computing, game studies, game artificial intelligence, user experience research, sensor technology, multi-modal interfaces and psychology that will advance the state-of-the-art in player experience research; affect modelling, induction, and sensing; affect-driven game adaptation and game-based learning and assessment. In 3 parts the books covers Theory, Emotion Modelling and Affect-Driven Adaptation, and Applications. This book will be of interest to researchers and scholars in the fields of game research, affective computing, human computer interaction, and artificial intelligence.

Emotional Machines

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Publisher : Springer Nature
ISBN 13 : 3658376414
Total Pages : 301 pages
Book Rating : 4.6/5 (583 download)

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Book Synopsis Emotional Machines by : Catrin Misselhorn

Download or read book Emotional Machines written by Catrin Misselhorn and published by Springer Nature. This book was released on 2023-09-01 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Can machines simulate, express or even have emotions? Is it a good to build such machines? How do humans react emotionally to them and how should such devices be treated from a moral point of view? This volume addresses these and related questions by bringing together perspectives from affective computing and emotional human-machine interaction, combining technological approaches with those from the humanities and social sciences. It thus relates disciplines such as philosophy, computer science, technology, psychology, sociology, design, and art. The volume offers readers interested in the phenomenon of emotional machines new perspectives from a variety of disciplines and addresses fundamental questions that will become pressing in the foreseeable future as emotional machines increasingly populate our everyday lives.

Marketing in Customer Technology Environments

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Publisher : Emerald Group Publishing
ISBN 13 : 1839096004
Total Pages : 272 pages
Book Rating : 4.8/5 (39 download)

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Book Synopsis Marketing in Customer Technology Environments by : Devanathan Sudharshan

Download or read book Marketing in Customer Technology Environments written by Devanathan Sudharshan and published by Emerald Group Publishing. This book was released on 2020-04-16 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the rise of virtual reality, augmented reality, the internet of things and more, customers are more engaged, more involved, and easier to reach than ever;while being inundated with increasing amounts of marketing material. This straightforward guide takes you through these new technologies and shows how to leverage them to reach new markets.

Advances in Virtual Agents and Affective Computing for the Understanding and Remediation of Social Cognitive Disorders

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Publisher : Frontiers Media SA
ISBN 13 : 2889197875
Total Pages : 140 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Advances in Virtual Agents and Affective Computing for the Understanding and Remediation of Social Cognitive Disorders by : Eric Brunet-Gouet

Download or read book Advances in Virtual Agents and Affective Computing for the Understanding and Remediation of Social Cognitive Disorders written by Eric Brunet-Gouet and published by Frontiers Media SA. This book was released on 2016-03-02 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in modern sciences occur thanks to within-fields discoveries as well as confrontation of concepts and methods from separated, sometimes distant, domains of knowledge. For instance, the fields of psychology and psychopathology benefited from accumulated contributions from cognitive neurosciences, which, in turn, received insights from molecular chemistry, cellular biology, physics (neuroimaging), statistics and computer sciences (data processing), etc. From the results of these researches, one can argue that among the numerous cognitive phenomena supposedly involved in the emergence the human intelligence and organized behavior, some of them are specific to the social nature of our phylogenetic order. Scientific reductionism allowed to divide the social cognitive system into several components, i.e. emotion processing and regulation, mental state inference (theory of mind), agency, etc. New paradigms were progressively designed to investigate these processes within highly-controlled laboratory settings. Moreover, the related constructs were successful at better understanding psychopathological conditions such as autism and schizophrenia, with partial relationships with illness outcomes. Here, we would like to outline the parallel development of concepts in social neurosciences and in other domains such as computer science, affective computing, virtual reality development, and even hardware technologies. While several researchers in neurosciences pointed out the necessity to consider naturalistic social cognition (Zaki and Ochsner, Ann N Y Acad Sci 1167, 16-30, 2009), the second person perspective (Schilbach et al., Behav Brain Sci 36(4), 393-414, 2013) and reciprocity (de Bruin et al., Front Hum Neurosci 6, 151, 2012), both computer and software developments allowed more and more realistic real-time models of our environment and of virtual humans capable of some interaction with users. As noted at the very beginning of this editorial, a new convergence between scientific disciplines might occur from which it is tricky to predict the outcomes in terms of new concepts, methods and uses. Although this convergence is motivated by the intuition that it fits well ongoing societal changes (increasing social demands on computer technologies, augmenting funding), it comes with several difficulties for which the current Frontiers in’ topic strives to bring some positive answers, and to provide both theoretical arguments and experimental examples. The first issue is about concepts and vocabulary as the contributions described in the following are authored by neuroscientists, computer scientists, psychopathologists, etc. A special attention was given during the reviewing process to stay as close as possible to the publication standards in psychological and health sciences, and to avoid purely technical descriptions. The second problem concerns methods: more complex computerized interaction models results in unpredictable and poorly controlled experiments. In other words, the assets of naturalistic paradigms may be alleviated by the difficulty to match results between subjects, populations, conditions. Of course, this practical question is extremely important for investigating pathologies that are associated with profoundly divergent behavioral patterns. Some of the contributions of this topic provide description of strategies that allowed to solve these difficulties, at least partially. The last issue is about heterogeneity of the objectives of the researches presented here. While selection criteria focused on the use of innovative technologies to assess or improve social cognition, the fields of application of this approach were quite unexpected. In an attempt to organize the contributions, three directions of research can be identified: 1) how innovation in methods might improve understanding and assessment of social cognition disorders or pathology? 2) within the framework of cognitive behavioral psychotherapies (CBT), how should we consider the use of virtual reality or augmented reality? 3) which are the benefits of these techniques for investigating severe mental disorders (schizophrenia or autism) and performing cognitive training? The first challenging question is insightfully raised in the contribution of Timmermans and Schilbach (2014) giving orientations for investigating alterations of social interaction in psychiatric disorders by the use of dual interactive eye tracking with virtual anthropomorphic avatars. Joyal, Jacob and collaborators (2014) bring concurrent and construct validities of a newly developed set of virtual faces expressing six fundamental emotions. The relevance of virtual reality was exemplified with two contributions focusing on anxiety related phenomena. Jackson et al. (2015) describe a new environment allowing to investigate empathy for dynamic FACS-coded facial expressions including pain. Based on a systematic investigation of the impact of social stimuli modalities (visual, auditory), Ruch and collaborators are able to characterize the specificity of the interpretation of laughter in people with gelotophobia (2014). On the issue of social anxiety, Aymerich-Franch et al. (2014) presented two studies in which public speaking anxiety has been correlated with avatars’ similarity of participants’ self-representations. The second issue focuses on how advances in virtual reality may benefit to cognitive and behavioral therapies in psychiatry. These interventions share a common framework that articulates thoughts, feelings or emotions and behaviors and proposes gradual modification of each of these levels thanks to thought and schema analysis, stress reduction procedures, etc. They were observed to be somehow useful for the treatment of depression, stress disorders, phobias, and are gaining some authority in personality disorders and addictions. The main asset of new technologies is the possibility to control the characteristics of symptom-eliciting stimuli/situations, and more precisely the degree to which immersion is enforced. For example, Baus and Bouchard (2014) provide a review on the extension of virtual reality exposure-based therapy toward recently described augmented reality exposure-based therapy in individuals with phobias. Concerning substance dependence disorders, Hone-Blanchet et collaborators (2014) present another review on how virtual reality can be an asset for both therapy and craving assessment stressing out the possibilities to simulate social interactions associated with drug seeking behaviors and even peers’ pressure to consume. The last issue this Frontiers’ topic deals with encompasses the questions raised by social cognitive training or remediation in severe and chronic mental disorders (autistic disorders, schizophrenia). Here, therapies are based on drill and practice or strategy shaping procedures, and, most of the time, share an errorless learning of repeated cognitive challenges. Computerized methods were early proposed for that they do, effortlessly and with limited costs, repetitive stimulations. While, repetition was incompatible with realism in the social cognitive domain, recent advances provide both immersion and full control over stimuli. Georgescu and al. (2014) exhaustively reviews the use of virtual characters to assess and train non-verbal communication in high-functioning autism (HFA). Grynszpan and Nadel (2015) present an original eye-tracking method to reveal the link between gaze patterns and pragmatic abilities again in HFA. About schizophrenia, Oker and collaborators (2015) discuss and report some insights on how an affective and reactive virtual agents might be useful to assess and remediate several defects of social cognitive disorders. About assessment within virtual avatars on schizophrenia, Park et al., (2014) focused on effect of perceived intimacy on social decision making with schizophrenia patients. Regarding schizophrenia remediation, Peyroux and Franck (2014) presented a new method named RC2S which is a cognitive remediation program to improve social cognition in schizophrenia and related disorders. To conclude briefly, while it is largely acknowledged that social interaction can be studied as a topic of its own, all the contributions demonstrate the added value of expressive virtual agents and affective computing techniques for the experimentation. It also appears that the use of virtual reality is at the very beginning of a new scientific endeavor in cognitive sciences and medicine.