Advances in Teratology

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Publisher :
ISBN 13 :
Total Pages : 212 pages
Book Rating : 4.:/5 (35 download)

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Book Synopsis Advances in Teratology by : David Henry Morgan Woollam

Download or read book Advances in Teratology written by David Henry Morgan Woollam and published by . This book was released on 1972 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Advances in Teratology

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Publisher :
ISBN 13 :
Total Pages : 297 pages
Book Rating : 4.:/5 (25 download)

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Book Synopsis Advances in Teratology by : David Henry Morgan Woollam

Download or read book Advances in Teratology written by David Henry Morgan Woollam and published by . This book was released on 1966 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Teratological Testing

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Publisher : Springer Science & Business Media
ISBN 13 : 940116651X
Total Pages : 357 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Teratological Testing by : T.V.N. Persaud

Download or read book Teratological Testing written by T.V.N. Persaud and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of birth defects has assumed an importance even greater now than in the past because mortality rates attributed to congenital anomalies have declined far less than those for other causes of death, such as infectious and nutritional diseases. It is estimated that as many as 50% of all pregnancies terminate as miscarriages. In the majority of cases this is the result of faulty development. Major congenital malformations are found in at least 2% of all liveborn infants, and 22% of all stillbirths and infant deaths are associated with severe congenital anomalies. Teratological studies of an experimental nature are neither ethical nor justifiable in humans. Numerous investigations have been carried out in laboratory animals and other experimental models in order to improve our understanding of abnormal intra-uterine development. In less than two decades the field of experimental teratology has advanced phenomenally. As a result of the wide range of information that is now accumulating, it has become possible to obtain an insight into the causes, mec.;hanisms and prevention of birth defects. However, considerable work will be needed before these problems can be resolved. The· contributions in this volume deal primarily with the areas of terato logical evaluation and the use of selected animal models for the study of con genital anomalies. It is not only a documentation of the latest experimental work, but it also indicates new and important areas for future research.

Advances in Teratology

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Publisher :
ISBN 13 :
Total Pages : 306 pages
Book Rating : 4.:/5 (436 download)

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Book Synopsis Advances in Teratology by :

Download or read book Advances in Teratology written by and published by . This book was released on 1967 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Catalog of Teratogenic Agents

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Publisher : JHU Press
ISBN 13 : 9780801879531
Total Pages : 564 pages
Book Rating : 4.8/5 (795 download)

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Book Synopsis Catalog of Teratogenic Agents by : Thomas H. Shepard

Download or read book Catalog of Teratogenic Agents written by Thomas H. Shepard and published by JHU Press. This book was released on 2004 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Links information on experimental teratogenic agents with the congenital defects in human beings.

Teratogenic Mechanisms

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Publisher : Springer Science & Business Media
ISBN 13 : 9401159106
Total Pages : 240 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Teratogenic Mechanisms by : T.V.N. Persaud

Download or read book Teratogenic Mechanisms written by T.V.N. Persaud and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of birth defects has assumed an importance even greater now than in the past because mortality rates attributed to congenital anomalies have declined far less than those for other causes of death, such as infectious and nutritional diseases. It is estimated that as many as 50% of all pregnancies terminate as miscarriages. In the majority of cases this is the result of faulty development. Major congenital malformations are found in at least 2% of all liveborn infants, and 22% of all stillbirths and infant deaths are associated with severe congenital anomalies. Teratological studies of an experimental nature are neither ethical nor justifiable in humans. Numerous investigations have been carried out in laboratory animals and other experimental models in order to improve our understanding of abnormal intra-uterine development. In less than two decades the field of experimental teratology has advanced phenomenally. As a result of the wide range of information that is now accumulating, it has become possible to obtain an insight into the causes, mechanisms and prevention of birth defects. However, considerable work will be needed before these problems can be resolved. This book brings together some of the more recent and important research findings related to the mechanisms and pathogenesis of abnormal develop ment. It is not only a documentation of the latest experimental work, but it also points out future directions that seem productive and challenging.

Advances in the Study of Birth Defects

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Publisher :
ISBN 13 :
Total Pages : 238 pages
Book Rating : 4.:/5 (6 download)

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Book Synopsis Advances in the Study of Birth Defects by : T. V. N. Persaud

Download or read book Advances in the Study of Birth Defects written by T. V. N. Persaud and published by . This book was released on 1980 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Environment and Birth Defects

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Publisher :
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Environment and Birth Defects by : James Graves Wilson

Download or read book Environment and Birth Defects written by James Graves Wilson and published by . This book was released on 1973 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Catalog of Teratogenic Agents

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Publisher :
ISBN 13 :
Total Pages : 440 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Catalog of Teratogenic Agents by : Thomas H. Shepard

Download or read book Catalog of Teratogenic Agents written by Thomas H. Shepard and published by . This book was released on 1980 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The first edition of the catalog was a noble achievement and the subsequent editions have each embodied major improvements." -- Teratology

Handbook of Teratology: Research procedures and data analysis

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (76 download)

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Book Synopsis Handbook of Teratology: Research procedures and data analysis by : James Graves Wilson

Download or read book Handbook of Teratology: Research procedures and data analysis written by James Graves Wilson and published by . This book was released on 1977 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Teratogenesis and Reproductive Toxicology

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Publisher : Springer Science & Business Media
ISBN 13 : 3642819192
Total Pages : 379 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Teratogenesis and Reproductive Toxicology by : E.M. Johnson

Download or read book Teratogenesis and Reproductive Toxicology written by E.M. Johnson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: The resolution of links between exposure to components of our complex environmental and causation of reproductive effects in the population constitutes an important problem in the field of toxicology. The focus of this volume is developmental toxicology, which represents one aspect of reproductive toxicology dealing with the study of adverse effects on the developing conceptus. Developmental toxicology, which includes teratogenesis as one of its manifesta tions, provides a fertile field for research in several basic and clinical disciplines; this field also receives input from several disoiplines such as developmental and molecu lar biology, pathology, pharmacology and toxicology, pediatrics and neonatology, and epidemiology. More recently we h~ve seen an emergence of interest in other fields such as perinatal physiology and postnatal behavior which have now become incorporated into the mainstream of research in this discipline. The present volume is an effort to provide a sampling of concepts currently under active investigation in several of the above fields. The authors have endeavored to provide up-to-date in formation on the following topics: detection and analysis of potential hazards to the conceptus in the workplace, pharmacokinetic aspects of the maternal/placental! fetal complex and its relationship to human birth defects, and probable mechanisms of teratogenesis as uncovered in certain well-defined situations. Also included are summaries of newer investigations on the emerging field of postnatal functional evaluations, i. e. , adverse effects on adult activities resultant from in utero exposure to toxic substances.

Genetic Disorders, Syndromology and Prenatal Diagnosis

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Publisher : Springer Science & Business Media
ISBN 13 : 9401166692
Total Pages : 257 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Genetic Disorders, Syndromology and Prenatal Diagnosis by : T.V.N. Persaud

Download or read book Genetic Disorders, Syndromology and Prenatal Diagnosis written by T.V.N. Persaud and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Birth defects have assumed an importance even greater now than in the past because infant mortality rates attributed to congenital anomalies have declined far less than those for other causes of death, such as infectious and nutritional diseases. As many as 50 % of all pregnancies terminate as miscarriages, and in the majority of cases this is the result of faulty intrauterine development. Major congenital malformations are present in at least 2 % of all liveborn infants, and 22 % of all stillbirths and infant deaths are associated with severe congenital anomalies. Not surprisingly, there has been a great proliferation of research into the problems of developmental abnormalities over the past few decades. This series, Advances in the Study of Birth Defects, was conceived in order to provide a comprehensive focal source of up-to-date information for physi cians concerned with the health of the unborn child and for research workers in the fields of fetal medicine and birth defects. The first four volumes featured recent experimental work on selected areas of high priority and intensive investigation, including mechanisms of teratogenesis, teratological evaluation, molecular and cellular aspects of abnormal development, and neural and behavioural teratology. It seems logical and timely that the clinical aspects should now be presented. Accordingly, leading experts were invited to review a broad range of common problems from the standpoint of embryology, aetiology, clinical manifestations, diagnosis and management. This volume deals with genetic disorders and prenatal diagnosis.

Animals and Medicine

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Publisher : Open Book Publishers
ISBN 13 : 1783741171
Total Pages : 246 pages
Book Rating : 4.7/5 (837 download)

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Book Synopsis Animals and Medicine by : Jack Botting

Download or read book Animals and Medicine written by Jack Botting and published by Open Book Publishers. This book was released on 2015-05-04 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease offers a detailed, scholarly historical review of the critical role animal experiments have played in advancing medical knowledge. Laboratory animals have been essential to this progress, and the knowledge gained has saved countless lives—both human and animal. Unfortunately, those opposed to using animals in research have often employed doctored evidence to suggest that the practice has impeded medical progress. This volume presents the articles Jack Botting wrote for the Research Defence Society News from 1991 to 1996, papers which provided scientists with the information needed to rebut such claims. Collected, they can now reach a wider readership interested in understanding the part of animal experiments in the history of medicine—from the discovery of key vaccines to the advancement of research on a range of diseases, among them hypertension, kidney failure and cancer.This book is essential reading for anyone curious about the role of animal experimentation in the history of science from the nineteenth century to the present.

Scientific Frontiers in Developmental Toxicology and Risk Assessment

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Publisher : National Academies Press
ISBN 13 : 0309070864
Total Pages : 348 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Scientific Frontiers in Developmental Toxicology and Risk Assessment by : National Research Council

Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

Problems of Birth Defects

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Publisher : Springer Science & Business Media
ISBN 13 : 9401166218
Total Pages : 395 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Problems of Birth Defects by : T.V.N. Persaud

Download or read book Problems of Birth Defects written by T.V.N. Persaud and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surprisingly, the beginning of a modern approach This collection of articles and commentaries is an to the problems of birth defects is relatively recent integration of information from many disciplines, and dates from Gregg's classical report in 1941 that and presents a comprehensive survey of both recent mothers who contracted rubella during the first tri and previously reported work related to the major mester of pregnancy gave birth to infants with severe aspects of birth defects. In particular, an attempt multiple anomalies. For the first time, an environ has been made to provide a critical assessment of mental agent was found to be teratogenic in man current concepts and to identify areas in need of and was documented in a thoroughly convincing further investigation. manner. Since then, many important discoveries The scope of this volume and space limitations and significant developments have been made, par precluded discussion of and reference to all papers ticularly in the areas of environmental teratogenesis, of relevance or importance: a work of the present hereditary mechanisms, and prenatal diagnosis. nature must necessarily be selective. Some good In recent years, there has been an impressive papers have been left out or given relatively little surge of interest in the causes and prevention of consideration. It is my hope that the list of Further birth defects. Undoubtedly this resulted not only References will be consulted and should compensate from the thalidomide tragedy, but also from the for this lack of completeness.

Abnormal Embryogenesis

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Publisher : Springer
ISBN 13 : 9789401166560
Total Pages : 246 pages
Book Rating : 4.1/5 (665 download)

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Book Synopsis Abnormal Embryogenesis by : T.V.N. Persaud

Download or read book Abnormal Embryogenesis written by T.V.N. Persaud and published by Springer. This book was released on 2012-02-14 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of birth defects has assumed an importance even greater now than in the past because mortality rates attributed to congenital anomalies have declined far less than those for other causes of death, such as infectious and nutritional diseases. It is estimated that as many as 50% of all pregnancies terminate as miscarriages. In the majority of cases this is the result of faulty development. Major congenital malformations are found in at least 2% of all liveborn infants, and 22% of all stillbirths and infant deaths are associated with severe congenital anomalies. Teratological studies of an experimental nature are neither ethical nor justifiable in humans. Numerous investigations have been carried out in laboratory animals and other experimental models in order to improve our understanding of abnormal intrauterine development. In less than two decades the field of experimental teratology has advanced phenomenally. As a result of the wide range of information that is now accumulating, it has become possible to obtain an insight into the causes, mechanisms, and prevention of birth defects. However, considerable work will be needed before these problems can be resolved. The comributions in this volume include some of the more recent and exciting observations on the cellular and molecular aspects of developmental defects. It is not only a documentation of the latest experimental work, but it also indicates new and important areas for future research.

Progress in drug research. 50.1998

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Publisher : Springer Science & Business Media
ISBN 13 : 9783764358211
Total Pages : 384 pages
Book Rating : 4.3/5 (582 download)

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Book Synopsis Progress in drug research. 50.1998 by : Ernst Jucker

Download or read book Progress in drug research. 50.1998 written by Ernst Jucker and published by Springer Science & Business Media. This book was released on 1998 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Drug Research is a prestigious book series (founded in 1959) which provides extensive expert-written reviews on a wide spectrum of highly topical areas in current pharmaceutical and pharmalogical research. Each volume contains fully cross-referencing indexes which link the volumes together, forming a virtually encyclopaedic work. The series thus serves as an important, time-saving source of information for researchers concerned with drug research and all those who need to keep abreast of the many recent developments in the quest for new and better medicines. Volume 50 in the series includes: P.N. Kaul: Drug discovery: Past, present and future M. Rohmer: Isoprenoid biosynthesis via the mevalonate -- independent route, a novel target for antibacterial drugs G. Edwards and A.H. Weston: Endothelium, -derived hyperpolarizing factor -- a critical appraisal R.W. Rockhold: Glutamatic involvement in psychomotor stimulant action J.M. Colacino and K.A. Staschke: The identification and development of antiviral agents for the treatment of chronic hepatitis B virus infection T.D. Johnson: Polyamines and cerebral ischemia