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Author : R. J. Maciunas
Publisher :
ISBN 13 : 9783131350619
Total Pages : 220 pages
Book Rating : 4.3/5 (56 download)
Download or read book Advanced Techniques in Central Nervous System Metastases written by R. J. Maciunas and published by . This book was released on 1999-01-01 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Robert J. Maciunas
Publisher : Thieme
ISBN 13 : 9781879284470
Total Pages : 344 pages
Book Rating : 4.2/5 (844 download)
Download or read book Advanced Techniques in Central Nervous System Metastases written by Robert J. Maciunas and published by Thieme. This book was released on 1998 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: The neurosurgical treatment of metastatic tumors involving the central nervous system is being transformed by recent advances in interactive image-guided technologies and cell-specific targeted biotherapeutics. Advanced Techniques in Central Nervous System Metastases presents the research and developments being incorporated into clinical practice. Advanced Techniques in Central Nervous System Metastases covers: The current treatment of brain metastases Metastases of primary CNS tumors Craniotomy for single and multiple cerebral metastases CNS involvement by systemic malignancy in children Cranial base surgery for invasive carcinomas Interactive image-guided techniques for the biopsy and resection of metastatic cerebral tumors Use of the free-electron laser for metastatic brain tumors Gamma knife radiosurgery Endovascular treatment Decompression and stabilization of spine metastases Plus much more! (Distributed by Thieme for the American Association of Neurological Surgeons)
Author : Rohan Ramakrishna
Publisher : Springer Nature
ISBN 13 : 303042958X
Total Pages : 725 pages
Book Rating : 4.0/5 (34 download)
Download or read book Central Nervous System Metastases written by Rohan Ramakrishna and published by Springer Nature. This book was released on 2020-05-27 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a multi-specialty book on the diagnosis, evaluation, and treatment of CNS metastases of the brain and spine. Written by renowned experts in their fields, the book covers essential contemporary topics in CNS metastases care. The book is divided into seven parts that begin with chapters that cover the fundamental biology of disease so that subsequent chapters on imaging, diagnosis, treatment, and palliation can be properly contextualized. This text also provides a framework for understanding the biology of radiation therapy so that radiation treatment options of the brain and spine can be more fully understood. New medications and technologies are reviewed from the perspective of maximizing efficacy and minimizing toxicity, independently and as combinatorial therapy. Central Nervous System Metastases: Diagnosis and Treatment serves as a practical reference for health care providers and trainees. It provides the comprehensive, detailed perspective required to provide holistic care to patients with metastatic disease to the brain and spine.
Author : Manmeet Ahluwalia
Publisher : Springer Nature
ISBN 13 : 3030234177
Total Pages : 421 pages
Book Rating : 4.0/5 (32 download)
Download or read book Central Nervous System Metastases written by Manmeet Ahluwalia and published by Springer Nature. This book was released on 2019-11-05 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives. Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach. Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.
Author : Lizza E.L Hendriks
Publisher : Frontiers Media SA
ISBN 13 : 2889457079
Total Pages : 94 pages
Book Rating : 4.8/5 (894 download)
Download or read book Central Nervous System Metastases in Lung Cancer Patients: From Prevention to Diagnosis and Treatment written by Lizza E.L Hendriks and published by Frontiers Media SA. This book was released on 2019-01-21 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approximately 40% of lung cancer patients will develop central nervous system (CNS) metastases during the course of their disease. Most of these are brain metastases, but up to 10% will develop leptomeningeal metastases. Known risk factors for CNS metastases development are small cell lung cancer (SCLC), adenocarcinoma histology, epidermal growth factor receptor (EGFR) mutant or anaplastic lymphoma kinase (ALK) rearranged lung cancer, advanced nodal status, tumor stage and younger age. CNS metastases can have a negative impact on quality of life (QoL) and overall survival (OS). The proportion of lung cancer patients diagnosed with CNS metastases has increased over the years due to increased use of brain imaging as part of initial cancer staging, advances in imaging techniques and better systemic disease control. Post contrast gadolinium enhanced magnetic resonance imaging (gd-MRI) is preferred, however when this is contra-indicated a contrast enhanced computed tomography (CE-CT) is mentioned as an alternative option. When CNS metastases are diagnosed, local treatment options consist of radiotherapy (stereotactic or whole brain) and surgery. Local treatment can be complicated by symptomatic radiation necrosis for which no high level evidence based treatment exists. Moreover, differential diagnosis with metastasis progression is difficult. Systemic treatment options have expanded over the last years. Until recently, chemotherapy was the only treatment option with a poor penetration in the CNS. Angiogenesis inhibitors are promising in the treatment of primary CNS tumors as well as radiation necrosis but clinical trials of anti-angiogenic agents in NSCLC have largely excluded patients with CNS metastases. Furthermore, research has also focused on methods to prevent development of CNS disease, for example with prophylactic cranial irradiation. Recently, checkpoint inhibitors have become available for NSCLC patients, and tyrosine kinase inhibitors (TKIs) have improved prognosis significantly in those with a druggable driver mutation. Newer TKIs are often designed to have better CNS penetration compared to first-generation TKIs. Despite advances in treatment options CNS metastases remain a problem in lung cancer and cause morbidity and mortality. This Research Topic provides an extensive resource of articles describing advances in CNS metastases management in lung cancer patients, from prevention to diagnosis and treatment.
Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)
Download or read book Central Nervous System Metastases in Lung Cancer Patients: From Prevention to Diagnosis and Treatment written by and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approximately 40% of lung cancer patients will develop central nervous system (CNS) metastases during the course of their disease. Most of these are brain metastases, but up to 10% will develop leptomeningeal metastases. Known risk factors for CNS metastases development are small cell lung cancer (SCLC), adenocarcinoma histology, epidermal growth factor receptor (EGFR) mutant or anaplastic lymphoma kinase (ALK) rearranged lung cancer, advanced nodal status, tumor stage and younger age. CNS metastases can have a negative impact on quality of life (QoL) and overall survival (OS). The proportion of lung cancer patients diagnosed with CNS metastases has increased over the years due to increased use of brain imaging as part of initial cancer staging, advances in imaging techniques and better systemic disease control. Post contrast gadolinium enhanced magnetic resonance imaging (gd-MRI) is preferred, however when this is contra-indicated a contrast enhanced computed tomography (CE-CT) is mentioned as an alternative option. When CNS metastases are diagnosed, local treatment options consist of radiotherapy (stereotactic or whole brain) and surgery. Local treatment can be complicated by symptomatic radiation necrosis for which no high level evidence based treatment exists. Moreover, differential diagnosis with metastasis progression is difficult. Systemic treatment options have expanded over the last years. Until recently, chemotherapy was the only treatment option with a poor penetration in the CNS. Angiogenesis inhibitors are promising in the treatment of primary CNS tumors as well as radiation necrosis but clinical trials of anti-angiogenic agents in NSCLC have largely excluded patients with CNS metastases. Furthermore, research has also focused on methods to prevent development of CNS disease, for example with prophylactic cranial irradiation. Recently, checkpoint inhibitors have become available for NSCLC patients, and tyrosine kinase inhibitors (TKIs) have improved prognosis significantly in those with a druggable driver mutation. Newer TKIs are often designed to have better CNS penetration compared to first-generation TKIs. Despite advances in treatment options CNS metastases remain a problem in lung cancer and cause morbidity and mortality. This Research Topic provides an extensive resource of articles describing advances in CNS metastases management in lung cancer patients, from prevention to diagnosis and treatment.
Author : Diane Palmieri
Publisher : Springer Science & Business Media
ISBN 13 : 9400752911
Total Pages : 234 pages
Book Rating : 4.4/5 (7 download)
Download or read book Central Nervous System Metastasis, the Biological Basis and Clinical Considerations written by Diane Palmieri and published by Springer Science & Business Media. This book was released on 2012-12-30 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a thorough survey of the biology and treatment of CNS metastasis, including natural history, risk factors, molecular biology, the blood-brain barrier, imaging, quality of life, surgery, chemotherapy, radiation and the future of targeted therapies.
Author : Edjah K. Nduom
Publisher : Elsevier Health Sciences
ISBN 13 : 0323761933
Total Pages : 209 pages
Book Rating : 4.3/5 (237 download)
Download or read book Metastases to the Central Nervous System, An Issue of Neurosurgery Clinics of North America written by Edjah K. Nduom and published by Elsevier Health Sciences. This book was released on 2020-09-24 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Neurosurgery Clinics, guest edited by Drs. Edjah Nduom and Jeff Olson, will focus on Metastases to the Central Nervous System. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: Epidemiology of metastatic CNS disease, Initial approach to the patient with a newly diagnosed solitary brain metastasis, Initial approach to the patient with multiple newly diagnosed brain metastases, When to consider a stereotactic biopsy for brain metastases, Techniques for open surgical resection of cerebral metastases, Laser ablation for cerebral metastases, Histopathological features and laboratory markers of common brain metastases, Recurrence vs radiation necrosis – evaluation and treatment, Anti-epileptic drugs for the management of cerebral metastases, Chemotherapy for the management of cerebral metastases, Approach to the management of metastatic leptomeningeal disease, Immune therapy for CNS metastases, Novel therapeutic targets for the treatment of cerebral metastases, Skull base metastases – diagnosis and management, and more.
Author : Zbigniew Petrovich
Publisher : Springer Science & Business Media
ISBN 13 : 3642564119
Total Pages : 632 pages
Book Rating : 4.6/5 (425 download)
Download or read book Combined Modality Therapy of Central Nervous System Tumors written by Zbigniew Petrovich and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Cancer Society anticipates that 16,500 patients will be diagnosed with primary malignant tumors of the central nervous system in 2000, with about 200,000 individuals presenting with brain metastases. The advances in the treatment of solid tumors have contributed significantly to the major increase in metastatic cancers to the brain. Of the primary malignant tumors of the brain, more than 50% are high-grade gliomas; the incidence has been increasing among older patients over the past decade. Major developments in new technologies in the treatment of primary brain tumors as well as metastatic disease are covered in depth. Even though management is difficult, advances are being made. This book is a concerted effort to present data regarding basic science research efforts alongside their translation into clinical practice using combined, integrated multimodal programs of treatment. Progress has been made, but innovatice approaches need to be pursued.
Author : Edjah K. Nduom
Publisher : Elsevier
ISBN 13 : 9780323761925
Total Pages : 240 pages
Book Rating : 4.7/5 (619 download)
Download or read book Metastases to the Central Nervous System, an Issue of Neurosurgery Clinics of North America, Volume 31-4 written by Edjah K. Nduom and published by Elsevier. This book was released on 2020-10-28 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Neurosurgery Clinics, guest edited by Drs. Edjah Nduom and Jeff Olson, will focus on Metastases to the Central Nervous System. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: Epidemiology of metastatic CNS disease, Initial approach to the patient with a newly diagnosed solitary brain metastasis, Initial approach to the patient with multiple newly diagnosed brain metastases, When to consider a stereotactic biopsy for brain metastases, Techniques for open surgical resection of cerebral metastases, Laser ablation for cerebral metastases, Histopathological features and laboratory markers of common brain metastases, Recurrence vs radiation necrosis - evaluation and treatment, Anti-epileptic drugs for the management of cerebral metastases, Chemotherapy for the management of cerebral metastases, Approach to the management of metastatic leptomeningeal disease, Immune therapy for CNS metastases, Novel therapeutic targets for the treatment of cerebral metastases, Skull base metastases - diagnosis and management, and more.
Author : Haotian Zhao
Publisher : Frontiers Media SA
ISBN 13 : 2889458555
Total Pages : 94 pages
Book Rating : 4.8/5 (894 download)
Download or read book Mechanisms and Therapy for Cancer Metastasis to the Central Nervous System written by Haotian Zhao and published by Frontiers Media SA. This book was released on 2019-05-15 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Springer
ISBN 13 : 9789400752924
Total Pages : 240 pages
Book Rating : 4.7/5 (529 download)
Download or read book Central Nervous System Metastasis, the Biological Basis and Clinical Considerations written by and published by Springer. This book was released on 2012-12-30 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Academies of Sciences Engineering and Medicine
Publisher :
ISBN 13 : 9780309683494
Total Pages : pages
Book Rating : 4.6/5 (834 download)
Download or read book Childhood Cancer and Functional Impacts Across the Care Continuum written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2021-09-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.
Author : David Schiff
Publisher : Elsevier
ISBN 13 : 0444638792
Total Pages : 304 pages
Book Rating : 4.4/5 (446 download)
Download or read book Metastatic Disease of the Nervous System written by David Schiff and published by Elsevier. This book was released on 2018-01-04 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metastatic Disease of the Nervous System, Volume 149, begins with an overview of the impact and range of direct neoplastic involvement of the central and peripheral nervous system, comprehensively reviewing all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy in their management, and the complications of these interventions. The clinical manifestations, diagnosis and treatment of leptomeningeal, dural, spinal epidural and plexus metastases are also covered in detail. - Covers all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy - Presents a multidisciplinary review of the evidence regarding accuracy of diagnostic testing and evidence-based reviews of therapies - Addresses metastatic diseases of the nervous system for residents, fellows and clinicians in neurology and oncology
Author : Elke Hattingen
Publisher : Springer
ISBN 13 : 3642450407
Total Pages : 166 pages
Book Rating : 4.6/5 (424 download)
Download or read book Brain Tumor Imaging written by Elke Hattingen and published by Springer. This book was released on 2015-09-02 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the basics, the challenges and the limitations of state of the art brain tumor imaging and examines in detail its impact on diagnosis and treatment monitoring. It opens with an introduction to the clinically relevant physical principles of brain imaging. Since MR methodology plays a crucial role in brain imaging, the fundamental aspects of MR spectroscopy, MR perfusion and diffusion-weighted MR methods are described, focusing on the specific demands of brain tumor imaging. The potential and the limits of new imaging methodology are carefully addressed and compared to conventional MR imaging. In the main part of the book, the most important imaging criteria for the differential diagnosis of solid and necrotic brain tumors are delineated and illustrated in examples. A closing section is devoted to the use of MR methods for the monitoring of brain tumor therapy. The book is intended for radiologists, neurologists, neurosurgeons, oncologists and other scientists in the biomedical field with an interest in neuro-oncology.
Author : Lee Roy Morgan
Publisher : BoD – Books on Demand
ISBN 13 : 953513051X
Total Pages : 216 pages
Book Rating : 4.5/5 (351 download)
Download or read book New Approaches to the Management of Primary and Secondary CNS Tumors written by Lee Roy Morgan and published by BoD – Books on Demand. This book was released on 2017-03-23 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several new concepts are reviewed and discussed in this book and allude to the transport of drugs bound to red blood cells into the vascular blood-brain barrier and into cancer cells. Such a transport system is novel and of potential therapeutic potential. It is the goal of this book to provide information and data that will be useful for others to develop new approaches for the management of CNS malignancies.
Author : Peter McL. Black
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 0781737311
Total Pages : 930 pages
Book Rating : 4.7/5 (817 download)
Download or read book Cancer of the Nervous System written by Peter McL. Black and published by Lippincott Williams & Wilkins. This book was released on 2005 with total page 930 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised to reflect the latest advances in neurosurgery, radiation oncology, chemotherapy, biological therapy, and the basic sciences, the Second Edition of this highly acclaimed volume is the most comprehensive, current reference on tumors of the central and peripheral nervous system. More than 100 of the foremost authorities present multimodality treatment strategies for specific tumor types and examine the mechanisms of tumorigenesis. Coverage includes state-of-the-art information on image-guided surgery, local delivery systems, intraoperative imaging, proton beam therapy, conformal systems, radiosurgery, new drugs and biological agents, and cell cycle deregulation and chromosomal abnormalities in tumorigenesis. This edition contains over 400 illustrations.
