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Author : Kenji Maeda
Publisher :
ISBN 13 :
Total Pages : 98 pages
Book Rating : 4.:/5 (248 download)
Download or read book Advanced Glycation End-products in Diabetes Mellitus and Renal Failure written by Kenji Maeda and published by . This book was released on 1996 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Angela D'Angelo
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805571356
Total Pages : 156 pages
Book Rating : 4.8/5 (55 download)
Download or read book Advanced Glycation End Products in Nephrology written by Angela D'Angelo and published by Karger Medical and Scientific Publishers. This book was released on 2001-01-01 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pathological role of advanced glycation end products (AGEs) and of oxidative-carbonylic stress is well known in the context of diabetes. Moreover, there is also strong evidence that they play a pivotal role in the pathogenesis of some chronic disorders related to uremia, and namely to cardiovascular complications and dialysis-related amyloidosis. They may even play a crucial role in the loss of function of the peritoneal membrane in patients on peritoneal dialysis, a problem which limits the duration of such a treatment.Written by some of the most authoritative European experts, this publication includes up-to-date contributions on AGEs as related to diabetic nephropathy, hemodialysis and, particularly, peritoneal dialysis. The topics covered range from basic research (e.g. novel pathogenic pathways triggered by AGEs) to clinical issues, including substitutive therapy in uremic diabetic patients as well as original and new results from a clinical trial on peritoneal dialysis with a new bag.This publication will be of interest to nephrologists as well as those working in the field of diabetes or otherwise involved in AGE research, giving an idea into what direction research in this complex field is going and which will probably be the major clinical breakthroughs in the near future.
Author : Pedro Cortes
Publisher : Springer Science & Business Media
ISBN 13 : 1597451533
Total Pages : 553 pages
Book Rating : 4.5/5 (974 download)
Download or read book The Diabetic Kidney written by Pedro Cortes and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and authoritative survey of recent findings, ideas, and hypotheses about the causes and treatment of diabetic nephropathy. The authors cover both the basic pathogenic mechanisms of the disease, as well as many of its clinical aspects of identification, management, and new therapeutic approaches. Highlights include an entire section devoted to novel approaches to studying diabetic nephropathy with the most advanced molecular techniques, and complete descriptions of the most up-to-date views on the diagnosis and treatment of the disease. The Diabetic Kidney offers both researchers and practicing clinicians a clear understanding of the of the progress that has been made regarding the pathogenesis of diabetic nephropathy and of the therapeutic interventions needed to prevent its development or treat it.
Author : Z.-H. Liui
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318026514
Total Pages : 274 pages
Book Rating : 4.3/5 (18 download)
Download or read book Podocytopathy written by Z.-H. Liui and published by Karger Medical and Scientific Publishers. This book was released on 2014-05-16 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.
Author : A. D'Angelo
Publisher :
ISBN 13 : 9783318006308
Total Pages : 0 pages
Book Rating : 4.0/5 (63 download)
Download or read book Advanced Glycation End Products in Nephrology written by A. D'Angelo and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pathological role of advanced glycation end products (AGEs) and of oxidative-carbonylic stress is well known in the context of diabetes. Moreover, there is also strong evidence that they play a pivotal role in the pathogenesis of some chronic disorders related to uremia, and namely to cardiovascular complications and dialysis-related amyloidosis. They may even play a crucial role in the loss of function of the peritoneal membrane in patients on peritoneal dialysis, a problem which limits the duration of such a treatment. Written by some of the most authoritative European experts, this publication includes up-to-date contributions on AGEs as related to diabetic nephropathy, hemodialysis and, particularly, peritoneal dialysis. The topics covered range from basic research (e.g. novel pathogenic pathways triggered by AGEs) to clinical issues, including substitutive therapy in uremic diabetic patients as well as original and new results from a clinical trial on peritoneal dialysis with a new bag. This publication will be of interest to nephrologists as well as those working in the field of diabetes or otherwise involved in AGE research, giving an idea into what direction research in this complex field is going and which will probably be the major clinical breakthroughs in the near future.
Author : Shamim I. Ahmad
Publisher : Springer Science & Business Media
ISBN 13 : 1461454417
Total Pages : 515 pages
Book Rating : 4.4/5 (614 download)
Download or read book Diabetes written by Shamim I. Ahmad and published by Springer Science & Business Media. This book was released on 2013-04-12 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes is a complex disease and is also one of the most common. It is very difficult to reach an accurate estimate for the global prevalence of diabetes since the standards and methods of data collection vary widely in different parts of the world. In addition, many potential sufferers are not included in the count because according to an estimate about 50% of cases remain undiagnosed for up to 10 years. However, according to an estimate for 2010, globally, there are about 285 million people (amounting to 6.4% of the adult population) suffering from this disease. This number is estimated to increase to 439 million by 2030 if no cure is found. The general increase in life expectancy, leading to an ageing population, and the global rise in obesity are two main reasons for the increase. With the basic platform set, Editor presents his views and advice to the readers, especially to diabetic patients suffering from T2DM, on the basis of his observations and information collected from other diabetics.
Author :
Publisher : Elsevier
ISBN 13 : 0443194033
Total Pages : 460 pages
Book Rating : 4.4/5 (431 download)
Download or read book Glycation written by and published by Elsevier. This book was released on 2024-07-11 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycation, Volume 125 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Vitamins and Hormones serials Updated release includes the latest information on Glycation
Author : Jaime Uribarri
Publisher : CRC Press
ISBN 13 : 1351646354
Total Pages : 581 pages
Book Rating : 4.3/5 (516 download)
Download or read book Dietary AGEs and Their Role in Health and Disease written by Jaime Uribarri and published by CRC Press. This book was released on 2017-10-30 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the many dietary factors associated with inflammation and oxidative stress, a specific group are food-derived pro-inflammatory and pro-oxidant compounds, so-called advanced glycation end products (AGEs). While AGEs have been recognized as factors in the pathogenesis of diabetic complications, the importance of AGEs of dietary origin as a factor in human disease is of more recent concern. This book presents data from the past two decades on the role of AGEs in causing chronic disease. It starts by defining the compounds passing through all the clinical diseases that have been associated with them and finishes by offering different therapeutic options to deal with the problem.
Author : Kar Neng Lai
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805597428
Total Pages : 288 pages
Book Rating : 4.8/5 (55 download)
Download or read book Diabetes and the Kidney written by Kar Neng Lai and published by Karger Medical and Scientific Publishers. This book was released on 2011 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive update on clinical and basic aspects of diabetic nephropathy Caused by an epidemic increase in obesity and diabetes and metabolic syndromes, diabetic nephropathy has become a leading cause of end-stage renal disease in many developed countries. The publication at hand provides a concise overview of the current state of clinical and basic research in the field. It starts with a summary of the epidemiology and genetics of diabetic nephropathy in different ethnic groups, followed by a review of its clinical manifestation, the link with the metabolic syndrome and obesity, and the pathology of diabetic nephropathy. Building on this basis, the latest findings on pathogenetic, epigenetic and inflammatory mechanisms are presented. The publication also looks at advances in the areas of tubulopathy and the kallikrein-kinin system as well as at the latest animal models and the role of lipoproteins and proteomics. This is followed by a discussion of promising therapeutic approaches such as experimental anti-fibrotic strategies, stem cell therapy and pancreatic transplantation; expert reviews on the emerging entity of new onset diabetes after transplantation and the preventive strategies for diabetic nephropathy conclude the material presented. Written by a panel of leading international experts, this book is highly recommended for nephrologists, diabetologists, internist, transplant physicians, scientists, geneticists, epidemiologists and stem cell biologists working in the field of diabetic nephropathy.
Author : John Chan
Publisher : BoD – Books on Demand
ISBN 13 : 9535105434
Total Pages : 180 pages
Book Rating : 4.5/5 (351 download)
Download or read book Diabetic Nephropathy written by John Chan and published by BoD – Books on Demand. This book was released on 2012-04-20 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Internationally renowned experts have provided data on their own studies, and discuss the relative usefulness of their work in relation to diabetic nephropathy. The first section describes the novel role of intrarenal renin-angiotensin-aldosterone system (RAAS) and oxidative stress in the development of diabetic nephropathy and discusses the current and novel pharmacological interventions in the treatment of diabetic nephropathy. The second section discusses other important contributors outside of the RAAS in the pathogenesis of diabetic nephropathy including AGE/RAGE, epithelial-mesenchymal-transition (EMT) and immune cytokines. Features: Provides novel information on various pathophysiological determinants in the development of diabetic nephropathy Provides novel information on various pharmacological interventions of diabetic nephropathy
Author : Laura D. Byham-Gray
Publisher : Springer Science & Business Media
ISBN 13 : 1627036857
Total Pages : 495 pages
Book Rating : 4.6/5 (27 download)
Download or read book Nutrition in Kidney Disease written by Laura D. Byham-Gray and published by Springer Science & Business Media. This book was released on 2014-01-23 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition in Kidney Disease, Second Edition addresses the relationships between nutrition and (1) normal kidney function and disease, (2) the progressiveness of chronic kidney disease (CKD) and strategies to prevent further compromise, and (3) the treatment and management of kidney failure especially during medical crises, such as acute kidney injury and its consequent nutritional therapies (e.g., enteral and parenteral nutrition). Demographic patterns, trends and outcomes in the current health care systems are explored in the United States and abroad. Disease prevention and management are presented over the entire lifespan, beginning with pregnancy, followed by infancy, childhood, adolescence, and adulthood, concluding with the elder years. Foundations for clinical practice are established by devoting a complete section towards conducting a comprehensive nutritional assessment, comprising of anthropometric, biochemical, clinical, physical parameters and psychosocial concerns unique to the kidney disease population. Nutritional therapy is also discussed across the spectrum of kidney disease, and pertinent aspects critical to successful management of disorders and conditions, such as bone disease, obesity, and nephrotic syndrome are explored. Nutrition in Kidney Disease, Second edition highlights cutting edge research in regards to exercise and functional outcomes, malnutrition and the inflammatory response, experimental therapies, and the use of complementary and alternative medicine, with a special emphasis on relevant preventative strategies.
Author : Sho-ichi Yamagishi
Publisher : Springer
ISBN 13 : 9811043760
Total Pages : 211 pages
Book Rating : 4.8/5 (11 download)
Download or read book Diabetes and Aging-related Complications written by Sho-ichi Yamagishi and published by Springer. This book was released on 2017-11-02 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses why and how the aging process is accelerated under diabetes, providing valuable and comprehensive information for the management of various types of diabetes- and aging-related disorders. Since several papers have shown that average life span and healthy life expectancy are reduced in diabetic patients, especially in those with a long history of disease, the early detection and treatment of diabetes-related complications are urgently needed in order to slow the aging process and help people successfully live with diabetes. Each chapter of this book addresses a specific diabetes and aging-related complication. The topics covered include not only diabetic vascular complications, the leading causes of morbidities and high mortality rates in both type 1 and type 2 diabetic patients, but also other aging-related complications such as Alzheimer’s disease, osteoporosis, periodontitis and cancer growth and metastasis. Experts on each topic discuss the background of the aging process and methods for coping with diabetes-related complications. The book as a whole, as well as the individual chapters, offer a valuable resource for researchers and practitioners in the fields of diabetic studies, gerontology, and aging science.
Author : G.B. Silva Junior
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 331806937X
Total Pages : 369 pages
Book Rating : 4.3/5 (18 download)
Download or read book Nephrology and Public Health Worldwide written by G.B. Silva Junior and published by Karger Medical and Scientific Publishers. This book was released on 2021-11-02 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nephrology is one of the fastest growing specialties in medicine. Nevertheless, kidney disease is one of the most serious unmet health needs in many countries. To provide healthcare access with the desirable equity worldwide, the nephrology community needs to discuss this public health issue and take part in decisions for elaboration of public health policies with more justice and equity. This book brings together key current public health problems that affect kidney function and illuminates them in contributions by an international group of nephrologists and general practitioners. The chapters review current knowledge and provide guidelines to manage these conditions and decrease the disease burden. At the end, developments in the digital era and their application to kidney disease treatment are synthesized, and a broader outlook on the future of nephrology is given. Ultimately, the publication aims to gather nephrology and public health expertise from researchers from all over the world, providing a broad vision of issues that must be discussed and overcome to guarantee a better treatment for patients with kidney diseases in the world today.
Author : Sara C. Zapico
Publisher : CRC Press
ISBN 13 : 1315354209
Total Pages : 200 pages
Book Rating : 4.3/5 (153 download)
Download or read book Mechanisms Linking Aging, Diseases and Biological Age Estimation written by Sara C. Zapico and published by CRC Press. This book was released on 2017-03-27 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on four of the hallmarks of aging: aspartic acid racemization, advanced glycation end products, telomere shortening and mitochondrial mutations; describing their role in aging and diseases; and their application to age-at-death estimation in forensic sciences in greater depth, displaying the interconnecting pathways among these processes. An additional chapter related to Epigenetics and its role in aging, diseases, and forensic age estimation is also included. This book is aimed at a broad audience: from students being introduced to aging, diseases, and forensic science research to scientists in biomedicine and forensics complementing their knowledge in their respective fields while also increasing their knowledge in other disciplines.
Author : Patrik Bast
Publisher : Nova Science Publishers
ISBN 13 : 9781536175479
Total Pages : 144 pages
Book Rating : 4.1/5 (754 download)
Download or read book Advanced Glycation End-products written by Patrik Bast and published by Nova Science Publishers. This book was released on 2020 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Advanced Glycation End-Products: Sources and Effects attempts to describe the role of advanced glycation end-products, particularly dietary advanced glycation end-products, in the pathological expansion of adipose tissue as well as their implications in the development of obesity associated complications. The effects of advanced glycation end-products on vasculature and their pathological implications are also described, focusing on the epigenetic mechanisms (particularly that of miRNA) modulating their effects. The authors summarize the information available on the impact of hyperglycemia on the influencing factors of non-enzymatic glycosylation, the formation of advanced glycation end-products, and the role of advanced glycation end-products and their specific receptors in diabetes. The role of advanced glycation end-products to diabetic complications is examined in conjunction with the protective role of the endogenous secretory receptor for advanced glycation end-products (esRAGE) and the therapeutic interventions that would mimic esRAGE activity. In closing, poly-L-lysine modified with advanced glycation end-products is prepared and used as an antigen to generate a single-chain fragment variable monoclonal antibody (scFv mAb) through phage display technology"--
Author : Agnes B. Fogo
Publisher : Springer Science & Business Media
ISBN 13 : 3642390803
Total Pages : 223 pages
Book Rating : 4.6/5 (423 download)
Download or read book Fundamentals of Renal Pathology written by Agnes B. Fogo and published by Springer Science & Business Media. This book was released on 2013-10-24 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Renal Pathology is a compact and up-to-date resource on the basics of renal pathology that will be of particular value for residents and fellows in training in renal pathology, general pathology, and nephrology, but will also serve as a handy reference for the more experienced. This second, revised and updated edition of the book offers an integrated approach based on contributions from established experts in the field. Key diseases are discussed within the context of clinical presentations, with the emphasis on clinicopathological correlation and differential diagnosis. Topics discussed include glomerular diseases with nephrotic or nephritic syndrome presentations; systemic and vascular diseases affecting the kidney, including diseases affecting the renal transplant; tubulointerstitial diseases; and plasma cell dyscrasias and associated diseases. Well-chosen color illustrations and electron micrographs enhance and complement the text.
Author : Carl Erik Mogensen
Publisher : Springer Science & Business Media
ISBN 13 : 1475719744
Total Pages : 420 pages
Book Rating : 4.4/5 (757 download)
Download or read book The Kidney and Hypertension in Diabetes Mellitus written by Carl Erik Mogensen and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first sporadic observations describing renal abnormalities in diabetes were published late in the 19th century, but systematic studies of the kidney in diabetes started only half a century ago after the paper by Cambier in 1934 and the much more famous study by Kimmelstiel and Wilson in 1936. These authors described two distinct features of renal involvement in diabetes: early hyperfiltration and late nephropathy. Diabetic nephropathy is, despite half a century of studies, still a very pertinent problem, renal disease in diabetes now being a very common cause of end-stage renal failure in Europe and North America and probably throughout the world. It is a very important part of the generalized vascular disease found in long-term diabetes as described by Knud Lundbaek in his mono graph Long-term Diabetes in 1953, published by Munks gaard, Copenhagen. Surprisingly, there has not been a comprehensive volume describing all aspects of renal involvement in diabetes, and the time is now ripe for such a volume summarizing the very considerable research activity within this field during the last decade and especially during the last few years. This book attempts to cover practically all aspects of renal involvement in diabetes. It is written by colleagues who are themselves active in the many fields of medical research covered in this volume: epidemiology, physiology and pathophysiology, laboratory methodology, and renal pathology. New studies deal with the dia gnosis and treatment of both incipient and overt nephropathy by metabolie, antihypertensive, and dietary invention.
