Adhesion Therapeutique

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Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease, An Issue of Hematology/Oncology Clinics

Author : Elliot Vichinsky
Publisher : Elsevier Health Sciences
ISBN 13 : 0323290000
Total Pages : 281 pages
Book Rating : 4.3/5 (232 download)

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Book Synopsis Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease, An Issue of Hematology/Oncology Clinics by : Elliot Vichinsky

Download or read book Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease, An Issue of Hematology/Oncology Clinics written by Elliot Vichinsky and published by Elsevier Health Sciences. This book was released on 2014-04-28 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Hematology/Oncology Clinics, guest edited by Dr. Elliott Vichinsky, is devoted to Sickle Cell Disease, and focuses on pathophysiology of hemoglobinopathies, therapeutic targets, and new approaches to correcting ineffective erythropoiesis and iron dysregulation. Articles in this issue include Polymerization and red cell membrane changes; Overview on reperfusion injury in the pathophysiology of SCD; Regulation of ineffective erythropoiesis in iron metabolism; Altering oxygen affinity; Cellular adhesion and the endothelium; Arginine therapy; Role of the hemostatic system on SCD pathophysiology and potential therapeutics; Adenosine signaling and novel therapies; New approaches to correcting ineffective erythropoiesis and iron dysregulation; New approaches to correcting ineffective erythropoiesis and iron dysregulation; Fetal hemoglobin induction; Gene therapy for hemoglobinopathies; and Oxidative injury and the role of antioxidant therapy.

Adherence to Long-term Therapies

Author : Eduardo Sabaté
Publisher : World Health Organization
ISBN 13 : 9789241545990
Total Pages : 232 pages
Book Rating : 4.5/5 (459 download)

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Book Synopsis Adherence to Long-term Therapies by : Eduardo Sabaté

Download or read book Adherence to Long-term Therapies written by Eduardo Sabaté and published by World Health Organization. This book was released on 2003 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report is based on an exhaustive review of the published literature on the definitions, measurements, epidemiology, economics and interventions applied to nine chronic conditions and risk factors.

Toward Anti-Adhesion Therapy for Microbial Diseases

Author : Itzahak Kahane
Publisher : Springer Science & Business Media
ISBN 13 : 1461304156
Total Pages : 288 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Toward Anti-Adhesion Therapy for Microbial Diseases by : Itzahak Kahane

Download or read book Toward Anti-Adhesion Therapy for Microbial Diseases written by Itzahak Kahane and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of pathogens resistant to conventional antimicrobial agents has forced us to intensify the efforts in search for new approaches to prevent infectious diseases. Such a direction was indicated in studies over the last two decades showing that adhesion of pathogens, primarily via glycoconjugate or protein receptors of the host tissue, is crucial for the infectious process. Moreover, it was found that infection can be prevented by blocking adhesion of the pathogen to mucosal surfaces of the host. The various aspects of interference with the process of microbial adhesion as a way of preventing diseases were the subject of the Bat-Sheva Seminar, "Towards Anti-Adhesion Therapy of Microbial Infectious Diseases," held in Zichron Yaakov, Israel, February 25 to March I, 1996. A major aim of the Bat-Sheva de Rothschild Foundation for the Advancement of Science in Israel, which sponsors a series of seminars, ours among them, is to provide the necessary tools and settings for international forums and exposure of young scientists and promising students to the state of the art of the field. This goal has been achieved during the week's discussions, and its major aspects are presented in this compendium. The seminar's participants, as well as the readers of this book, thank the founder and Foundation for their support. This book includes the major themes of this rapidly growing area. However, by no means do we intend to cover every bit and piece in it. The book's first section deals with the lectin-sugar interactions and their inhibitors.

Stratégie Thérapeutique Dans la Maladie de Hodgkin

Author : Reiner Somers
Publisher : John Libbey Eurotext
ISBN 13 : 9780861962266
Total Pages : 464 pages
Book Rating : 4.9/5 (622 download)

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Book Synopsis Stratégie Thérapeutique Dans la Maladie de Hodgkin by : Reiner Somers

Download or read book Stratégie Thérapeutique Dans la Maladie de Hodgkin written by Reiner Somers and published by John Libbey Eurotext. This book was released on 1990 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents proceedings of the Paris International Workshop & Symposium held on 28 to 30, June 1989.

Matricellular Receptors as Potential Targets in Anti-Cancer Therapeutic Strategies

Author : Hervé Emonard
Publisher : Frontiers Media SA
ISBN 13 : 2889450244
Total Pages : 131 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Matricellular Receptors as Potential Targets in Anti-Cancer Therapeutic Strategies by : Hervé Emonard

Download or read book Matricellular Receptors as Potential Targets in Anti-Cancer Therapeutic Strategies written by Hervé Emonard and published by Frontiers Media SA. This book was released on 2016-11-22 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: The invasive character of a primary cancer is greatly dependent on numerous interactions between tumor cells and their extracellular surroundings. Matricellular receptors are defined as (cell-surface) receptors that bind extracellular matrix (ECM) structural proteins and soluble factors dynamically acting on ECM homeostasis. Matricellular receptors mediate numerous signalings from the extracellular environment to cell nucleus and drive main biological functions that are cell growth, survival and migration. Numerous data from the last decade evidence that matricellular receptors are biosensors that allow to a tumor cell answering to microenvironmental variations, and in this sense they are important contributors to tumor cell malignancy. Matricellular receptors represent thus valuable targets for the development of original anti-cancer strategies. Original reports, bibliographic reviews or hypotheses are welcome to improve the basic knowledge of matricellular receptor properties, their spatio-temporal regulation, the dynamic formation of complex receptors and the impact of such interactions on the invasive properties of tumor cells. Biological, biophysical and pharmacological, as well as in silico contributions will be appreciated.

Research and Review Studies

Author :
Publisher :
ISBN 13 :
Total Pages : 104 pages
Book Rating : 4.3/5 (126 download)

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Book Synopsis Research and Review Studies by :

Download or read book Research and Review Studies written by and published by . This book was released on 2001 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Surgical Consent

Author : Rajesh Nair
Publisher : Oxford University Press, USA
ISBN 13 : 0199595585
Total Pages : 762 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis Handbook of Surgical Consent by : Rajesh Nair

Download or read book Handbook of Surgical Consent written by Rajesh Nair and published by Oxford University Press, USA. This book was released on 2012 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Surgical Consent is a new and valuable tool, written by experts, and offering practical guidance in the principles of consent, alongside procedure-specific information on risks and benefits.

Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis-Associated Cancer

Author : Pandurangan, Ashok Kumar
Publisher : IGI Global
ISBN 13 : 1799835812
Total Pages : 309 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis-Associated Cancer by : Pandurangan, Ashok Kumar

Download or read book Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis-Associated Cancer written by Pandurangan, Ashok Kumar and published by IGI Global. This book was released on 2021-03-29 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, epidemiological studies have shown a significant increase of incidences regarding ulcerative colitis (UC) in most regions of the world. At present, a common therapeutic modality for inflammatory bowel disorders is the use of anti-inflammatory agents, including sulfasalazine and acetylsalicylic acid, steroid hormone, and other immunosuppressive agents. Most of these treatments are symptomatic and palliative because the etiology of the disease is not yet established. As a result of no proper drug available to treat UC, patients with UC are at a high risk of developing colitis-associated cancer (CAC). It is necessary to understand the genetic and molecular mechanisms involved in the pathogenesis of UC and CAC that lead to the path of new drug discoveries. Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis-Associated Cancer provides innovative insights that describe the fundamental understanding of UC and CAC and the molecular mechanisms behind the etiology as well as modern diagnostic methods that are employed in UC and CAC. Current prevention and therapeutic strategies practiced in the pre-clinical level are also discussed. The content within this publication examines alternative medicine and dietary intervention and drug delivery techniques. It is designed for healthcare professionals, physicians, academicians, researchers, R&D organizations, and medical students involved in drug discovery and clinical and therapeutic research.

The Molecular Pathology of Autoimmune Diseases

Author : Argyrios N Theofilopoulos
Publisher : CRC Press
ISBN 13 : 9789057026454
Total Pages : 1518 pages
Book Rating : 4.0/5 (264 download)

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Book Synopsis The Molecular Pathology of Autoimmune Diseases by : Argyrios N Theofilopoulos

Download or read book The Molecular Pathology of Autoimmune Diseases written by Argyrios N Theofilopoulos and published by CRC Press. This book was released on 2002-12-06 with total page 1518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Remarkable advances have been made in the pathogenesis of autoimmunity, such as with bone marrow transplantation, which is becoming a powerful strategy in treating certain life-threatening diseases. The Molecular Pathology of Autoimmune Diseases is a concise and centralized resource for information on the topic, with a special focus on the molecular and genetic basis of these disorders. Dozens of international experts devote themselves to illuminating the reader in this volume, with discussions on the basic aspects of autoimmune processes to systemic and organ-specific diseases. This volume is an invaluable reference to students and professionals in immunology and related fields.

Hematology

Author : American Society of Hematology. Education Program
Publisher :
ISBN 13 :
Total Pages : 516 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Hematology by : American Society of Hematology. Education Program

Download or read book Hematology written by American Society of Hematology. Education Program and published by . This book was released on 1998 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research and Review Studies from Malawi National Tuberculosis Control Programme

Author :
Publisher :
ISBN 13 :
Total Pages : 100 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Research and Review Studies from Malawi National Tuberculosis Control Programme by :

Download or read book Research and Review Studies from Malawi National Tuberculosis Control Programme written by and published by . This book was released on 2001 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Human Cell Transformation

Author : Johng S. Rhim
Publisher : Springer Science & Business Media
ISBN 13 : 1461402549
Total Pages : 239 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Human Cell Transformation by : Johng S. Rhim

Download or read book Human Cell Transformation written by Johng S. Rhim and published by Springer Science & Business Media. This book was released on 2011-09-15 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rhim and Kremer’s state-of-the-art volume on Human Cell Transformation: Role of Stem Cells and the Microenvironment highlights the latest findings on the current state of human cell transformation model systems and provides the insight into the molecular and cellular changes involved in the conversion of normal cells to neoplastic cells. Chapters cover all recently developed novel human cell models. In addition, the rapidly growing fields of knowledge regarding not only stem cells in cancer progression, but also the role of the microenvironments in human carcinogenesis are discussed. A wealth of topics is presented including: · Derivation of epithelial, fibroblastic, and hematopoietic in vitro model systems · Oncogenes · Tumor suppressor genes · Viral transformation · In vitro model systems for viral, chemical and radiation carcinogenesis · Cell aging · The multistep nature of human carcinogenesis · The role of stem cells and the microenvironment in tumorigenesis · The genes involved in multistep carcinogenesis Unique in both scope and focus – devoted solely to human cell transformation systems – Human Cell Transformation: Role of Stem Cells and the Microenvironment provides unparalleled, in-depth coverage for cancer researchers, cell and molecular biologists, hematologists, virologists, and workers in related fields. Essential reading for everyone who needs to be kept up-to-date in this fast-paced area! Features ؠ Multistep models ؠ Breast cancer/Stem cells ؠ Prostate cancer/Stem cells ؠ Multistep / Genes

Virulence and Gene Regulation

Author : Juan-Luis Ramos
Publisher : Springer Science & Business Media
ISBN 13 : 1441990844
Total Pages : 555 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Virulence and Gene Regulation by : Juan-Luis Ramos

Download or read book Virulence and Gene Regulation written by Juan-Luis Ramos and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pseudomonas comprises three volumes covering the biology of pseudomonads in a wide context, including the niches they inhabit, the taxonomic relations among members of this group, the molecular biology of gene expression in different niches and under different environmental conditions, the analysis of virulence traits in plants, animals and human pathogens as well as the determinants that make some strains useful for biotechnological applications and promotion of plant growth. There has been growing interest in pseudomonads and a particular urge to understand the biology underlying the complex metabolism of these ubiquitous microbes. These bacteria are capable of colonizing a wide range of niches, including the soil, the plant rhizosphere and phylosphere, and animal tissues; more recently they have attracted attention because of their capacity to form biofilms, a characteristic with potentially important medical and environmental implications. The three volumes cover the following topics: - Taxonomy, - Genomics, - Life styles, - Cell Architecture, - Virulence, - Regulation, - Macromolecules, - Alternative Respiratory Substrates, - Catabolism and Biotransformations. Pseudomonas will be of use to all researchers working on these bacteria, particularly those studying microbiology, plant crops, pathogenesis, and chemical engineering. Advanced students in biology, medicine and agronomy will also find these three volumes a valuable reference during their studies.

Hemostasis and Thrombosis

Author :
Publisher :
ISBN 13 :
Total Pages : 910 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Hemostasis and Thrombosis by :

Download or read book Hemostasis and Thrombosis written by and published by . This book was released on 1970 with total page 910 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monthly, with annual cumulation. Recurring bibliography from MEDLARS data base. Index medicus format. Entries arranged under subject, review, and author sections. Subject, author indexes.

Malaria Immunology

Author : Peter Perlmann
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3805573766
Total Pages : 422 pages
Book Rating : 4.8/5 (55 download)

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Book Synopsis Malaria Immunology by : Peter Perlmann

Download or read book Malaria Immunology written by Peter Perlmann and published by Karger Medical and Scientific Publishers. This book was released on 2002-01-01 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite extensive efforts to control it, malaria is still one of the most devastating infectious diseases worldwide. This book, now in its second edition, provides a broad and up-to-date overview of the rapidly expanding field of malaria immunology and its importance in the control of this disease. The first section deals with the malaria parasite and its interactions with both the vertebrate host and the mosquitoes which transmit the disease. In the second part, the mechanisms of immunity and their regulation by environmental and genetic factors are discussed. Finally, this volume contains several chapters on malaria vaccine development, describing the application of the most recent vaccine technologies as well as ongoing and planned vaccine trials. Authored by well-recognized experts, this volume not only demonstrates the rapid progress being made in the search for vaccines against malaria, but also broadens our understanding of immunity to infection in general. It is therefore highly recommended reading for all scientists and professionals in the fields of immunology, infection and vaccine development.

Fibrinolysis, Thrombolysis, and Blood Clotting: a Bibliography

Author :
Publisher :
ISBN 13 :
Total Pages : 914 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Fibrinolysis, Thrombolysis, and Blood Clotting: a Bibliography by :

Download or read book Fibrinolysis, Thrombolysis, and Blood Clotting: a Bibliography written by and published by . This book was released on 1970 with total page 914 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Regulation of Gene Expression in the Tumor Environment

Author : Menashe Bar-Eli
Publisher : Springer Science & Business Media
ISBN 13 : 1402083416
Total Pages : 155 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Regulation of Gene Expression in the Tumor Environment by : Menashe Bar-Eli

Download or read book Regulation of Gene Expression in the Tumor Environment written by Menashe Bar-Eli and published by Springer Science & Business Media. This book was released on 2008-08-25 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is now becoming very clear that the development and progression of tumor towards the malignant (metastatic) phenotype depends tightly on the interaction between the tumor cells and the tumor microenvironment. Tumor cells respond to stimuli generated within the tumor microenvironment for their growth advantage while the tumor cell themselves reshape and remodel the architecture and function of their extracellular matrices. The term tumor microenvironment is a wide umbrella consisting of stromal cells such as fibroblasts and endothelial cells and infiltration immune cells including T and B cells, macrophages, and other inflammatory cells (PMNs). These different components of the tumor microenvironment could have stimulatory and inhibitory effects on tumor progression by regulating the gene expression repertoire within the tumor cells on one hand and the stroma cells on the other. In this volume we have seven contributors who will discuss several different aspects on the cross talk within the tumor microenvironment components leading to the acquisition of the metastatic phenotype. It is our hope that these state-of-the-art studies will shed further light on our understanding of these complicated processes.