Activation Of Hormone And Growth Factor Receptors

Download Activation Of Hormone And Growth Factor Receptors full books in PDF, epub, and Kindle. Read online Activation Of Hormone And Growth Factor Receptors ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Activation of Hormone and Growth Factor Receptors

Author : Michael N. Alexis
Publisher : Springer Science & Business Media
ISBN 13 : 9400919360
Total Pages : 320 pages
Book Rating : 4.4/5 (9 download)

DOWNLOAD NOW!

Book Synopsis Activation of Hormone and Growth Factor Receptors by : Michael N. Alexis

Download or read book Activation of Hormone and Growth Factor Receptors written by Michael N. Alexis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the papers presented in the NATO Advanced Research Workshop "Activation of Hormone and Growth Factor Receptors: Molecular Mechanisms and Consequences" held in Nafplion, Greece on September 25-30, 1988. The objective of NATO ARW is to assess the state of-the-art in a given scientific area and to formulate recommendations for future research in emerging areas of science by promoting international scientific contacts. In the Nafplion meeting this objective was reached by an international group of speakers, senior Greek scientists and graduates involved in relevant research areas. The Workshop was made possible by the generous support of the Scientific Council of NATO. We thank Drs. G. Sinclair and L.V. daCunha, Directors of the NATO ARW's and ASI's (Advanced Study Institutes) respectively, for their wholehearted support and advice. The International Union of Biochemistry awarded additional travel grants leading to increased international participation. Furthermore, the Secretariat of Science and Technology, the Ministry of Culture and Sciences and the National Hellenic Research Foundation contributed financially and by supporting personnel. We sincerely thank all these organizations for their support. Our heartful thanks are also extended to the Mayor of the Municipality of Nafplion, Mr.

Cooperation of Liver Cells in Health and Disease

Author : Z. Kmiec
Publisher : Springer Science & Business Media
ISBN 13 : 3642565530
Total Pages : 154 pages
Book Rating : 4.6/5 (425 download)

DOWNLOAD NOW!

Book Synopsis Cooperation of Liver Cells in Health and Disease by : Z. Kmiec

Download or read book Cooperation of Liver Cells in Health and Disease written by Z. Kmiec and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better understood. The development of methods for isolation and co-culturing various types of liver cells has established that they communicate and cooperate via secretion of various intercellular mediators. This monograph summarizes multiple data that suggest the important role of cellular cross-talk for the functions of both normal and diseased liver. Special features of the book include concise presentation of the majority of detailed data in 19 tables. Original schemes allow for the clear illustration of complicated intercellular relationships. This is the first ever presentation of the newly emerging field of liver biology, which is important for hepatic function in health and disease and opens new avenues for therapeutic interventions.

Holland-Frei Cancer Medicine

Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2004 pages
Book Rating : 4.1/5 (19 download)

DOWNLOAD NOW!

Book Synopsis Holland-Frei Cancer Medicine by : Robert C. Bast, Jr.

Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Receptor Activation by Antigens, Cytokines, Hormones, and Growth Factors

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (757 download)

DOWNLOAD NOW!

Book Synopsis Receptor Activation by Antigens, Cytokines, Hormones, and Growth Factors by :

Download or read book Receptor Activation by Antigens, Cytokines, Hormones, and Growth Factors written by and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Growth Hormone in Adults

Author : Anders Juul
Publisher : Cambridge University Press
ISBN 13 : 9780521641883
Total Pages : 536 pages
Book Rating : 4.6/5 (418 download)

DOWNLOAD NOW!

Book Synopsis Growth Hormone in Adults by : Anders Juul

Download or read book Growth Hormone in Adults written by Anders Juul and published by Cambridge University Press. This book was released on 2000-04-27 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised new edition reviews the substantial advances in our understanding of the vital role of growth hormone (GH) in maintaining adult health, and the resulting disorders from GH deficiency. The first edition, published in 1996, provided a pioneering overview of the subject; this new edition provides an even more comprehensive account, fully updated with the latest research, clinical applications, and references. The therapeutic benefits of GH treatment in GH deficiency are thoroughly evaluated, including effects on metabolism, cardiac function, exercise performance, psychosocial aspects, and aging and gender-specific effects. This compilation by the world's leading experts covers clinical investigation, diagnosis and treatment issues, and encompasses new knowledge of the control and action of GH secretion. This volume is the most authoritative, comprehensive, and detailed account available and will be an essential source of reference for all endocrinologists.

Signalling from Internalised Growth Factor Receptors

Author : Inger Helene Madshus
Publisher : Springer Science & Business Media
ISBN 13 : 3540694943
Total Pages : 208 pages
Book Rating : 4.5/5 (46 download)

DOWNLOAD NOW!

Book Synopsis Signalling from Internalised Growth Factor Receptors by : Inger Helene Madshus

Download or read book Signalling from Internalised Growth Factor Receptors written by Inger Helene Madshus and published by Springer Science & Business Media. This book was released on 2013-06-05 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews knowledge on the interconnection of signal transduction and endocytosis/intracellular trafficking. The chapters cover knowledge obtained by using different model systems. The first chapter deals with Receptor Tyrosin Kinases (RTKs) with emphasis on the Epidermal Growth Factor Receptor (EGF receptor) and the Platelet Derived Growth Factor Receptor (PDGF receptor). The second chapter deals with the RTK c-Met and with how this RTK becomes carcinogenic. The third chapter reviews recent understanding on the mechanisms of action of the numerous fibroblast growth factors and their receptors. In the fourth chapter we learn about the trafficking of and signalling from the Growth Hormone Receptor and how this receptor is controlled by ubiquitination. The fifth chapter is devoted to the Interleukin II receptor, essential for activation of T cells. Links between ubiquitination, signalling, endocytosis, and sorting are reviewed. The last chapter discusses current views on how monoubiquitination controls both signalling and trafficking and thereby the final outcome of receptor activation.

Binding of Ligand, Dimerization, Self-phosphorylation, and Activation of a Protein Tyrosine Kinase

Author : Jennifer Miller Sherrill
Publisher :
ISBN 13 :
Total Pages : 362 pages
Book Rating : 4.:/5 (318 download)

DOWNLOAD NOW!

Book Synopsis Binding of Ligand, Dimerization, Self-phosphorylation, and Activation of a Protein Tyrosine Kinase by : Jennifer Miller Sherrill

Download or read book Binding of Ligand, Dimerization, Self-phosphorylation, and Activation of a Protein Tyrosine Kinase written by Jennifer Miller Sherrill and published by . This book was released on 1997 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protooncogenes and Growth Factors in Steroid Hormone Induced Growth and Differentiation

Author : Sohaib A. Khan
Publisher : CRC Press
ISBN 13 : 9780849386725
Total Pages : 298 pages
Book Rating : 4.3/5 (867 download)

DOWNLOAD NOW!

Book Synopsis Protooncogenes and Growth Factors in Steroid Hormone Induced Growth and Differentiation by : Sohaib A. Khan

Download or read book Protooncogenes and Growth Factors in Steroid Hormone Induced Growth and Differentiation written by Sohaib A. Khan and published by CRC Press. This book was released on 1993-12-17 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protooncogenes and Growth Factors in Steroid Hormone Induced Growth and Differentiation reviews current information regarding the complex nature of hormone-induced cell growth and differentiation. The contributors examine the emerging consensus that protooncogenes and growth factors mediate perhaps the most crucial steps leading to cell growth and differentiation. The primary objective of this book is to unite the status of current research related to protooncogenes and growth factors from diverse physiological systems to help readers gain a comprehensive understanding of the subject. Leading researchers have contributed outstanding chapters pertaining to steroid hormone-regulated cell growth and differentiation in normal and/or neoplastic tissues. This book will appeal to basic science researchers, clinicians, industrial researchers, and graduate students.

Hormone Signaling

Author : Vincent Goffin
Publisher : Springer Science & Business Media
ISBN 13 : 9780792376606
Total Pages : 340 pages
Book Rating : 4.3/5 (766 download)

DOWNLOAD NOW!

Book Synopsis Hormone Signaling by : Vincent Goffin

Download or read book Hormone Signaling written by Vincent Goffin and published by Springer Science & Business Media. This book was released on 2002-03-31 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multicellular organisms require a means of intracellular communication to organize and develop the complex body plan that occurs during embryogenesis and then for cell and organ systems to access and respond to an ever changing environmental milieu. Mediators of this constant exchange of information are growth factors, neurotransmmitters, peptide and protein hormones which bind to cell surface receptors and transduce their signals from the extracellular space to the intracellular compartment. Via multiple signaling pathways, receptors of this general class affect growth, development and differentiation. Smaller hydrophobic signaling molecules, such as steroids and non-steroid hormones, vitamins and metabolic mediators interact with a large family of nuclear receptors. These receptors function as transcription factors affecting gene expression, to regulate the multiple aspects of animal and human physiology, including development, reproduction and homeostasis. The aim of this book is to cover various aspects of intracellular signaling involving hormone receptors.

Insulin-Like Growth Factors in Development, Cancers and Aging

Author : Haim Werner
Publisher : MDPI
ISBN 13 : 3036507701
Total Pages : 196 pages
Book Rating : 4.0/5 (365 download)

DOWNLOAD NOW!

Book Synopsis Insulin-Like Growth Factors in Development, Cancers and Aging by : Haim Werner

Download or read book Insulin-Like Growth Factors in Development, Cancers and Aging written by Haim Werner and published by MDPI. This book was released on 2021-08-30 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue of Cells on “Insulin-Like Growth Factors in Development, Cancers and Aging” provides a collection of modern articles dealing with the role of insulin-like growth factors (IGF1) in cancer biology, aging and development. Featured articles explore basic and clinical aspects of the IGF1 system, including post-genomic analyses as well as novel approaches to target the IGF1 receptor (IGF1R) in oncology.

Hormone Signaling

Author : Vincent Goffin
Publisher : Springer Science & Business Media
ISBN 13 : 1475736002
Total Pages : 340 pages
Book Rating : 4.4/5 (757 download)

DOWNLOAD NOW!

Book Synopsis Hormone Signaling by : Vincent Goffin

Download or read book Hormone Signaling written by Vincent Goffin and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multicellular organisms require a means of intracellular communication to organize and develop the complex body plan that occurs during embryogenesis and then for cell and organ systems to access and respond to an ever changing environmental milieu. Mediators of this constant exchange of information are growth factors, neurotransmmitters, peptide and protein hormones which bind to cell surface receptors and transduce their signals from the extracellular space to the intracellular compartment. Via multiple signaling pathways, receptors of this general class affect growth, development and differentiation. Smaller hydrophobic signaling molecules, such as steroids and non-steroid hormones, vitamins and metabolic mediators interact with a large family of nuclear receptors. These receptors function as transcription factors affecting gene expression, to regulate the multiple aspects of animal and human physiology, including development, reproduction and homeostasis. The aim of this book is to cover various aspects of intracellular signaling involving hormone receptors.

Signalling from Internalised Growth Factor Receptors

Author : Inger Helene Madshus
Publisher : Springer
ISBN 13 : 9783540210382
Total Pages : 190 pages
Book Rating : 4.2/5 (13 download)

DOWNLOAD NOW!

Book Synopsis Signalling from Internalised Growth Factor Receptors by : Inger Helene Madshus

Download or read book Signalling from Internalised Growth Factor Receptors written by Inger Helene Madshus and published by Springer. This book was released on 2004-07-09 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book will concentrate on how growth factor receptors are down-regulated by endocytosis and intracellular trafficking. The authors will further discuss what is currently understood about the effect of cellular microenvironments on signal transduction.

Molecular Biology of The Cell

Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

DOWNLOAD NOW!

Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Peptide Growth Factors and Their Receptors I

Author : Michael B. Sporn
Publisher : Springer Science & Business Media
ISBN 13 : 3642492959
Total Pages : 811 pages
Book Rating : 4.6/5 (424 download)

DOWNLOAD NOW!

Book Synopsis Peptide Growth Factors and Their Receptors I by : Michael B. Sporn

Download or read book Peptide Growth Factors and Their Receptors I written by Michael B. Sporn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 811 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume treatise, the collected effort of more than 50 authors, represents the first comprehensive survey of the chemistry and biology of the set of molecules known as peptide growth factors. Although there have been many symposia on this topic, and numerous publications of reviews dealing with selected subsets of growth factors, the entire field has never been covered in a single treatise. It is essential to do this at the present time, as the number of journal articles on peptide growth factors now makes it almost impossible for anyone person to stay informed on this subject by reading the primary literature. At the same time it is becoming increasingly apparent that these substances are of universal importance in biology and medicine and that the original classification of these molecules, based on the laboratory setting of their discovery, as "growth factors," "lymphokines," "cytokines," or "colony stimulating factors," was quite artifactual; they are in fact the basis of a com mon language for intercellular communication. As a set they affect essentially every cell in the body, and in this regard they provide the basis to develop a unified science of cell biology, germane to all of biomedical research. This treatise is divided into four main sections. After three introductory chapters, its principal focus is the detailed description of each of the major peptide growth factors in 26 individual chapters.

Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy

Author : G V Sherbet
Publisher : Elsevier
ISBN 13 : 0123878209
Total Pages : 368 pages
Book Rating : 4.1/5 (238 download)

DOWNLOAD NOW!

Book Synopsis Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy by : G V Sherbet

Download or read book Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy written by G V Sherbet and published by Elsevier. This book was released on 2011-07-12 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. Humanised monoclonal antibodies raised against growth factor receptors have proved to be valuable for targeted cancer treatment and in patient management. This book reviews the latest developments providing insights into the signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for therapeutic deployment. Provides a fundamental understanding of the basic functions of growth factors and their receptors, describing how they are linked in biological processes Aids the development of therapeutic treatments for cancer Focuses on the interrelationships and convergence of growth factors and their receptors in development and pathogenesis and encourages greater cooperation and integration in the areas of developmental, cancer and cancer therapeutic research

Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors

Author : Derek Leroith
Publisher : Springer Science & Business Media
ISBN 13 : 1468456857
Total Pages : 505 pages
Book Rating : 4.4/5 (684 download)

DOWNLOAD NOW!

Book Synopsis Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors by : Derek Leroith

Download or read book Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors written by Derek Leroith and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential element in the development and functional integrity of all organisms is intercellular communication. This is achieved by the secretion of soluble messenger molecules which subsequently interact with receptor-effector pathways in the responsive cells. Hormones are traditionally defined as chemical messengers synthesized by endocrine glands. Unlike hormones produced by endocrine glands, growth factors are hormone-related substances produced by many tissues and play an important role in controlling growth and development. While the exact physiological roles of growth factors have yet to be elucidated, they play important roles in the regulation of cellular proliferation and/or differentiation during ontogenesis, growth and differentiation. During recent years there has been a substantial increase in research related to peptide growth factors, their receptors, and modes of action. With the discovery and characterization of numerous growth factors, it became clear that these growth factors had multiple features in common with classic hormones as well as with oncogenes. Furthermore, there are distinct families of growth factors based either on structural or functional similarities.

Signal Transduction through Growth Factor Receptors

Author : Y. Kitagawa
Publisher : Elsevier Science
ISBN 13 : 9781559383448
Total Pages : 236 pages
Book Rating : 4.3/5 (834 download)

DOWNLOAD NOW!

Book Synopsis Signal Transduction through Growth Factor Receptors by : Y. Kitagawa

Download or read book Signal Transduction through Growth Factor Receptors written by Y. Kitagawa and published by Elsevier Science. This book was released on 1994-06-15 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intense interest has been focused on the proliferation and differentiation of cells in multicellular organisms, because these events play a key role in embryogenesis, and coordinate the development and maintenance of the whole body by recruiting the mature cells with specific functions and regulating the formation of organs. Proteins, called growth factors, are mainly responsible for determining the fate of cells. The actions of growth factors are mediated by their interaction with specific receptors composed of an extracellular ligand-binding portion, a membrane spanning region, and a cytoplasmic region. The most important question is: How is the interaction of a ligand with its receptor transferred through the cytoplasmic membrane into the intracellular machinery that governs cell behavior? Tremendous efforts devoted to cloning growth factor receptors have made it possible to dissect receptor structures into functional domains: a ligand-binding site, a signal transducer region, and a regulatory domain. The first exciting finding was that receptors for epidermal growth factor (EGF), insulin, insulin-like growth factor (JGF), platelet-derived growth factor (PDGF), and several other growth factors were tyrosine kinases that were regulated by binding to individual specific ligands; the receptors are membrane-associated allosteric enzymes. In addition to the tyrosine kinase receptor family, a new receptor family has recently been found which has no tyrosine kinase domain, but has two characteristic conserved features (two pairs of cysteines and a Trp-Ser-X-Trp-Ser motif) in the extracellular region. Receptors of prolactin, growth hormone, and several hemopoietic growth factors including IL-2, IL-3, IL-5, IL-6, granulocyte colony-stimulating factor (G-CSF), granulocyte/macrophage colony-stimulating factor (GM-CSF), and erythropoietin belong to this new family. Some chapters selected for this volume deal with two tyrosine kinase receptors (receptors for insulin and hepatocyte growth factor), six receptors (for IL-3, IL-5, IL-6, G-CSF, GM-CSF, and erythropoietin) in a new receptor family, and one unique receptor (IL-1 receptor) that does not belong to any known receptor family. Emphasis on a new receptor family is possible because of remarkable progress in the elucidation of receptor compnents that construct high-affinity ligand binding sites and signal transducers. Although we are still far from a full understanding of the molecular bases connecting ligand binding with cell behavior, the editors believe that one can appreciate through these authoritative reviews where the field is now and where it is proceeding in the years ahead.