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Author : I. V. Torgov
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (315 download)
Download or read book Achievements in the Total Synthesis of Natural Steroids written by I. V. Torgov and published by . This book was released on 1965 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : A. A. Akhrem
Publisher : Springer Science & Business Media
ISBN 13 : 1475705875
Total Pages : 368 pages
Book Rating : 4.4/5 (757 download)
Download or read book Total Steroid Synthesis written by A. A. Akhrem and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the appearance of the Russian edition of this monograph (1967), the main tendencies of the development of total synfuesis have not changed. The accelerated accumulation of experimental material is continuing, mainly in the form of the improvement of already-existing synthesis schemes. The main new advance is the development of asymmetric syn theses with intermediates that have made it possible to avoid the main dis advantage of total synthesis - the formation of racemic final compounds. The most important work that has appeared since the appearance of the Russian edition is given in an Appendix to the book. Apart from this, only a very slight rearrangement of the material and of some of the schemes has been carried out for the American edition. A. A. Akhrem Yu. A. Titov Moscow, July 1968 v Preface to the Russian Edition Steroids are one of the most interesting and most widely distributed and, at the same time, one of the most structurally complex groups of natural compounds. In spite of this, the great theoretical and practical importance of steroids for biology and medicine has led to very intensive scientific research work on their synthesis. The numerous methods for obtaining steroids developed at the present time can be divided into four main groups: isolation from natural sources, microbiological synthesis, partial synthesis from natural raw material already containing the steroid skeleton, and, finally, total chemical synthesis from precursors of com paratively simple structure.
Author : Jie Jack Li
Publisher : Springer Science & Business Media
ISBN 13 : 3642340652
Total Pages : 292 pages
Book Rating : 4.6/5 (423 download)
Download or read book Total Synthesis of Natural Products written by Jie Jack Li and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.
Author : John D. Roberts
Publisher :
ISBN 13 : 9780805383218
Total Pages : 1596 pages
Book Rating : 4.3/5 (832 download)
Download or read book Basic Principles of Organic Chemistry written by John D. Roberts and published by . This book was released on 1977 with total page 1596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction what is organic chemistry all about?; Structural organic chemistry the shapes of molecules functional groups; Organic nomenclature; Alkanes; Stereoisomerism of organic molecules; Bonding in organic molecules atomic-orbital models; More on nomenclature compounds other than hydrocarbons; Nucleophilic substitution and elimination reactions; Separation and purification identification of organic compounds by spectroscopic techniques; Alkenes and alkynes. Ionic and radical addition reactions; Alkenes and alkynes; Oxidation and reduction reactions; Acidity or alkynes.
Author : Daniel Lednicer
Publisher : John Wiley & Sons
ISBN 13 : 111995729X
Total Pages : 154 pages
Book Rating : 4.1/5 (199 download)
Download or read book Steroid Chemistry at a Glance written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 2011-06-20 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term steroid has become virtually synonymous with drug abuse in sport to the majority of the public. However these steroids - androgens - actually comprise only a single relatively small class of biologically active steroids, and are overshadowed by a large collection of compounds, a sizeable number of which are commercial drugs that share the same structural carbon skeleton. The development of these drugs has led to a large body of organic chemistry often denoted as "Steroid Chemistry". Steroid Chemistry At A Glance provides a concise overview of the main principles and reactions of steroid chemistry. Topics covered include: history, isolation and structure determination of steroids steroid nomenclature and stereochemistry natural sources of steroids synthesis and reactions of aromatic a-ring steroids, androstanes, and pregnanes steroids with a spirolactone at position 17 steroids with hetrocyclic ring A compounds derived from cholesterol Based on the highly successful and student friendly "at a glance" approach, the information is presented in integrated, self contained double page spreads of text and illustrative material. Students of chemistry and pharmacy using Steroid Chemistry at a Glance will find they have a resource with which they can quickly, concisely and confidently acquire, regularly review and revise the basic facts that underpin the properties, synthesis and reactions of this important class of natural products. It will also serve as a handy bench reference for postgraduates and professional chemists.
Author : Pei-Qiang Huang
Publisher : John Wiley & Sons
ISBN 13 : 1118605403
Total Pages : 512 pages
Book Rating : 4.1/5 (186 download)
Download or read book Efficiency in Natural Product Total Synthesis written by Pei-Qiang Huang and published by John Wiley & Sons. This book was released on 2018-10-16 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. • Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science • Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis • Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section • Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals
Author :
Publisher :
ISBN 13 :
Total Pages : 874 pages
Book Rating : 4.3/5 (91 download)
Download or read book Research Awards Index written by and published by . This book was released on 1988 with total page 874 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher : Butterworth-Heinemann
ISBN 13 : 0080862543
Total Pages : 387 pages
Book Rating : 4.0/5 (88 download)
Download or read book Progress in Medicinal Chemistry written by and published by Butterworth-Heinemann. This book was released on 2011-09-22 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Medicinal Chemistry
Author :
Publisher :
ISBN 13 :
Total Pages : 328 pages
Book Rating : 4.3/5 (91 download)
Download or read book Recent Developments in the Chemistry of Natural Carbon Compounds written by and published by . This book was released on 1965 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paul M. Dewick
Publisher : John Wiley & Sons
ISBN 13 : 9780471496410
Total Pages : 524 pages
Book Rating : 4.4/5 (964 download)
Download or read book Medicinal Natural Products written by Paul M. Dewick and published by John Wiley & Sons. This book was released on 2002-01-03 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals. Structured according to biosynthetic pathway, it is written from a chemistry-based approach.
Author : S. Görög
Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 440 pages
Book Rating : 4.3/5 (91 download)
Download or read book Analysis of Steroid Hormone Drugs written by S. Görög and published by Elsevier Science & Technology. This book was released on 1978 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : E.J. Corey
Publisher : Рипол Классик
ISBN 13 : 5885010811
Total Pages : 447 pages
Book Rating : 4.8/5 (85 download)
Download or read book The logic of chemical synthesis written by E.J. Corey and published by Рипол Классик. This book was released on 1991 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jorge António Ribeiro Salvador
Publisher : BoD – Books on Demand
ISBN 13 : 1789855152
Total Pages : 144 pages
Book Rating : 4.7/5 (898 download)
Download or read book Chemistry and Biological Activity of Steroids written by Jorge António Ribeiro Salvador and published by BoD – Books on Demand. This book was released on 2020-02-26 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: The steroid scaffold continues to be the structural basis of new drugs for a variety of targets and diseases. Indeed, steroids interact with enzymes and receptors in a strikingly specific manner. Chemistry and Biological Activity of Steroids aims to provide an updated overview of recent advances in the medicinal chemistry of steroids. Novel synthetic methods in the steroids field, including steroid biotransformations, new steroids able to tackle steroid receptors, and steroid enzymes with clinical relevance, are critically reviewed in this book. Furthermore, the diverse physiopathological roles of oxysterols and their therapeutic value are also discussed.
Author :
Publisher :
ISBN 13 :
Total Pages : 686 pages
Book Rating : 4.:/5 (319 download)
Download or read book Books from Hungary written by and published by . This book was released on 1968 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : W. H. Sebrell
Publisher : Academic Press
ISBN 13 : 1483220133
Total Pages : 620 pages
Book Rating : 4.4/5 (832 download)
Download or read book The Vitamins written by W. H. Sebrell and published by Academic Press. This book was released on 2014-04-24 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Vitamins, Second Edition, Volume III: Chemistry, Physiology, Pathology, Methods covers an understanding of how each vitamin functions in animals and plants. The book describes the chemistry, industrial production, biogenesis, biochemistry, deficiency effects, requirements, pharmacology, and pathology of choline, vitamin D group, essential fatty acids, inositols, and vitamin K group. The text also describes the occurrence and effects of vitamin deficiency and the direct evidence of disease in humans. Chemists, physiologists, pathologists, and students taking related courses will find the book useful.
Author : Hitosi Nozaki
Publisher : Elsevier
ISBN 13 : 148327912X
Total Pages : 441 pages
Book Rating : 4.4/5 (832 download)
Download or read book Current Trends in Organic Synthesis written by Hitosi Nozaki and published by Elsevier. This book was released on 2016-10-27 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Trends in Organic Synthesis is a collection of papers presented at the Fourth International Conference on Organic Synthesis, held in Tokyo, Japan on August 22-27, 1982. This conference brings together the significant achievements in the diversified frontier fields of organic synthesis. This book is composed of 33 chapters. The first chapters focus on the synthesis of biologically active natural compounds, including metabolites of arachidonic acid, erythromycin A, verrucarins, steroids, anthracyclines, terpenes, yeast alanine t-RNA, beta-lactam antibiotics, and palitoxin. Other chapters deal with the central problems in stereoselective and chiral synthesis, as well as processes of high degree of stereochemical control and asymmetric induction. These chapters also describe chiral pool synthesis by means of carbohydrate precursors. This book also examines the methodologies in organic synthesis using reagents with boron, aluminum, transition metals, silicon, phosphorus, and sulfur. The remaining chapters are devoted to reactions involving radical initiated ring closure, small ring hydrogenolysis, annulene synthesis, vicarious nucleophilic substitution of aromatic hydrogen, and dichlorine monoxide mediated powerful chlorination. This book is of value to organic chemists and allied scientists.
Author : Robert T. Blickenstaff
Publisher : Academic Press
ISBN 13 : 148321642X
Total Pages : 345 pages
Book Rating : 4.4/5 (832 download)
Download or read book Total Synthesis of Steroids written by Robert T. Blickenstaff and published by Academic Press. This book was released on 2013-10-22 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Chemistry, Volume 30: Total Synthesis of Steroids provides an overall view of steroid total synthesis, including the general approaches, special problems, stereochemical complexities, expansion or contraction of rings, and insertion of hetero atoms. The book discusses the process of designing total syntheses; the biogenetic-like steroid synthesis, including cyclization of terminal epoxides as well as the total synthesis from nonepoxide precursors; and the synthesis of equilenin, estrone, bisdehydrodoisynolic acid, 18,19-bisnorprogesterone, 19-norpregnanes, and heterocyclic steroids. The text also describes the application of ABD intermediates in the Torgov synthesis; the synthesis of carbocyclics and thiasteroids; and the synthesis from p-anisylcyclohexanes and from C-5, C-8 bridged intermediates. The synthesis based on the type of reaction used in the condensation of the A fragment with the CD portion, as well as the methods of total synthesis in the preparation of 8-azasteroids and 8,13-diazasteroids are also considered. The book further tackles the synthesis of epiandrosterone, cortisone, aldosterone, 3ß-hydroxy-5a-pregnan-20-one, latifoline, conessine, and ring C aromatic steroids; the synthesis of trans-benzohydrindane derivatives and other common derivatives; and the synthesis of CD intermediates. Chemists, biochemists, and people involved in the study of steroid total syntheses will find the book invaluable.
