A Structural Perspective on Respiratory Complex I

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Publisher : Springer Science & Business Media
ISBN 13 : 9400741383
Total Pages : 281 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis A Structural Perspective on Respiratory Complex I by : Leonid Sazanov

Download or read book A Structural Perspective on Respiratory Complex I written by Leonid Sazanov and published by Springer Science & Business Media. This book was released on 2012-05-11 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book contains chapters written by leaders in the research on the structure and function of respiratory complex I. It will provide a concise and authoritative summary of the current knowledge on complex I of respiratory chains. This enzyme is central to energy metabolism and is implicated in many human neurodegenerative diseases, as well as in aging. Until recently it was poorly understood on a structural level, and this book will provide a timely reference resource. Such a book was not published previously. The last time a minireview series on complex I were published was in 2001, and since then complex I field changed quite dramatically.

Cytochrome Oxidase

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Publisher :
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Cytochrome Oxidase by : Mårten Wikström

Download or read book Cytochrome Oxidase written by Mårten Wikström and published by . This book was released on 1981 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Mitochondrial Oxidative Phosphorylation

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Publisher : Springer Science & Business Media
ISBN 13 : 1461435730
Total Pages : 378 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Mitochondrial Oxidative Phosphorylation by : Bernhard Kadenbach

Download or read book Mitochondrial Oxidative Phosphorylation written by Bernhard Kadenbach and published by Springer Science & Business Media. This book was released on 2012-06-23 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will describe the nuclear encoded genes and their expressed proteins of mitochondrial oxidative phosphorylation. Most of these genes occur in eukaryotic cells, but not in bacteria or archaea. The main function of mitochondria, the synthesis of ATP, is performed at subunits of proton pumps (complexes I, III, IV and V), which are encoded on mitochondrial DNA. The nuclear encoded subunits have mostly a regulatory function. However, the specific physiological functions of the nuclear encoded subunits of complexes I, III, IV, and V are mostly unknown. New data indicates that they are essential for life of higher organisms, which is characterized by an adult life without cell division (postmeiotic stage) in most tissues, after the juvenile growth. For complex IV (cytochrome c oxidase) some of these subunits occur in tissue-specific (subunits IV, VIa, VIb, VIIa, VIII), developmental-specific (subunits IV, VIa, and VIIa) as well as species-specific isoforms. Defective genes of some subunits were shown to induce mitochondrial diseases. Mitochondrial genes and human diseases will also be covered.

Anatomy and Physiology

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Author :
Publisher :
ISBN 13 : 9781947172807
Total Pages : 0 pages
Book Rating : 4.1/5 (728 download)

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Book Synopsis Anatomy and Physiology by : J. Gordon Betts

Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Natural Products Targeting Clinically Relevant Enzymes

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Publisher : John Wiley & Sons
ISBN 13 : 3527342052
Total Pages : 348 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Natural Products Targeting Clinically Relevant Enzymes by : Paula B. Andrade

Download or read book Natural Products Targeting Clinically Relevant Enzymes written by Paula B. Andrade and published by John Wiley & Sons. This book was released on 2017-12-04 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has seen the reappearance of natural products as a valuable source of potent therapeutics. Here, experts on bioactive natural products cover the full spectrum of clinically relevant enzymes that are known to be targeted by natural products. Key enzymes include acetylcholine esterase, angiotensin-I-converting enzyme, cyclooxygenase, dihydrofolate reductase, phospholipase A2, respiratory complexes, and many more. By connecting the diversity of medicinal natural product sources with their potential clinical applications, this volume serves as a companion for the medicinal chemist looking for innovative small molecule compounds as well as for pharmacologist interested in the clinical effects and mode of action of herbal and traditional medicines.

Concepts of Biology

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Publisher :
ISBN 13 : 9789888407453
Total Pages : 618 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Concepts of Biology by : Samantha Fowler

Download or read book Concepts of Biology written by Samantha Fowler and published by . This book was released on 2018-01-07 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.

How Tobacco Smoke Causes Disease

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Publisher :
ISBN 13 :
Total Pages : 728 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis How Tobacco Smoke Causes Disease by :

Download or read book How Tobacco Smoke Causes Disease written by and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Structure and Physics of Viruses

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Publisher : Springer Science & Business Media
ISBN 13 : 9400765525
Total Pages : 728 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Structure and Physics of Viruses by : Mauricio G. Mateu

Download or read book Structure and Physics of Viruses written by Mauricio G. Mateu and published by Springer Science & Business Media. This book was released on 2013-06-04 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contemplates the structure, dynamics and physics of virus particles: From the moment they come into existence by self-assembly from viral components produced in the infected cell, through their extracellular stage, until they recognise and infect a new host cell and cease to exist by losing their physical integrity to start a new infectious cycle. (Bio)physical techniques used to study the structure of virus particles and components, and some applications of structure-based studies of viruses are also contemplated. This book is aimed first at M.Sc. students, Ph.D. students and postdoctoral researchers with a university degree in biology, chemistry, physics or related scientific disciplines who share an interest or are actually working on viruses. We have aimed also at providing an updated account of many important concepts, techniques, studies and applications in structural and physical virology for established scientists working on viruses, irrespective of their physical, chemical or biological background and their field of expertise. We have not attempted to provide a collection of for-experts-only reviews focused mainly on the latest research in specific topics; we have not generally assumed that the reader knows all of the jargon and all but the most recent and advanced results in each topic dealt with in this book. In short, we have attempted to write a book basic enough to be useful to M.Sc and Ph.D. students, as well as advanced and current enough to be useful to senior scientists with an interest in Structural and/or Physical Virology.

Cytochrome Complexes: Evolution, Structures, Energy Transduction, and Signaling

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Author :
Publisher : Springer
ISBN 13 : 9401774811
Total Pages : 739 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Cytochrome Complexes: Evolution, Structures, Energy Transduction, and Signaling by : William A. Cramer

Download or read book Cytochrome Complexes: Evolution, Structures, Energy Transduction, and Signaling written by William A. Cramer and published by Springer. This book was released on 2016-06-14 with total page 739 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction that describes the origin of cytochrome notation also connects to the history of the field, focusing on research in England in the pre-World War II era. The start of the modern era of studies on structure-function of cytochromes and energy-transducing membrane proteins was marked by the 1988 Nobel Prize in Chemistry, given to J. Deisenhofer, H. Michel, and R. Huber for determination of the crystal structure of the bacterial photosynthetic reaction center. An ab initio logic of presentation in the book discusses the evolution of cytochromes and hemes, followed by theoretical perspectives on electron transfer in proteins and specifically in cytochromes. There is an extensive description of the molecular structures of cytochromes and cytochrome complexes from eukaryotic and prokaryotic sources, bacterial, plant and animal. The presentation of atomic structure information has a major role in these discussions, and makes an important contribution to the broad field of membrane protein structure-function.

Biological Inorganic Chemistry

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Publisher : University Science Books
ISBN 13 : 9781891389436
Total Pages : 794 pages
Book Rating : 4.3/5 (894 download)

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Book Synopsis Biological Inorganic Chemistry by : Ivano Bertini

Download or read book Biological Inorganic Chemistry written by Ivano Bertini and published by University Science Books. This book was released on 2007 with total page 794 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II.

Neurodegenerative Diseases

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Publisher : Springer
ISBN 13 : 3319571931
Total Pages : 542 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Neurodegenerative Diseases by : Philip Beart

Download or read book Neurodegenerative Diseases written by Philip Beart and published by Springer. This book was released on 2017-07-03 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a timely overview of critical advances in molecular and cellular neurobiology, covers key methodologies driving progress, and highlights key future directions for research on neuronal injury and neurodegeneration relevant to neuronal brain pathologies. The editors bring together contributions from internationally recognized workers in the field to provide an up to date account of how and why molecular and cellular neurobiology is such an important area for clinical neuroscience. Understanding the molecular aspects of a number of neurodegenerative conditions such as Parkinson's or Alzheimer's disease for the purpose of improving patient management remains a major challenge of neurobiology be it from the basic or clinical perspective. A strategic evaluation of research contributions and the power of modern methods will help advance knowledge over the next years.

Mechanisms of Primary Energy Transduction in Biology

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Publisher : Royal Society of Chemistry
ISBN 13 : 1788013638
Total Pages : 396 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Mechanisms of Primary Energy Transduction in Biology by : Mårten Wikström

Download or read book Mechanisms of Primary Energy Transduction in Biology written by Mårten Wikström and published by Royal Society of Chemistry. This book was released on 2017-11-21 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the events of primary energy transduction in life processes. Life as we know it depends on pumping protons across membranes. New tools to study the protein complexes involved has led to recent intensified progress in the field. Primary Energy Transduction in Biology focusses on recent structural results and new biophysical insights. These have been made possible by recent advances in high-resolution protein structures, in physical techniques to study reactions in real time, and in computational methods to study and refine both structures and their dynamics. Written and edited by leading experts, chapters discuss the latest key questions in cell respiration, photosynthesis, bioenergetics, proton transfer, electron transfer and membrane transport. Biochemists, biophysicists and chemical biologists will find this book an essential resource for a complete understanding of the molecular machines of bioenergetics.

Respiratory Diseases of the Newborn Infant

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Publisher : European Respiratory Society
ISBN 13 : 1849841365
Total Pages : 387 pages
Book Rating : 4.8/5 (498 download)

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Book Synopsis Respiratory Diseases of the Newborn Infant by : Sinha, Ian P

Download or read book Respiratory Diseases of the Newborn Infant written by Sinha, Ian P and published by European Respiratory Society. This book was released on 2021-06-01 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: So much of our lung health throughout life is determined by what happens before birth and when we are born. Managing respiratory problems in newborn infants requires experience and teamwork, an understanding of the background to the problems, and knowledge of the evidence behind the clinical options available. In this Monograph, science, evidence and expertise are brought together in a collection of comprehensive, state-of-the-art reviews that cover: the structure and function of the newborn respiratory system; neonatal lung disease in preterm infants; developmental, structural and functional diseases of the respiratory system; and more. This book will prove a valuable resource for neonatal clinicians, scientists researching the area and adult clinicians managing lung health.

Molecular Bioenergetics

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Publisher :
ISBN 13 :
Total Pages : 218 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Molecular Bioenergetics by : American Chemical Society. Meeting

Download or read book Molecular Bioenergetics written by American Chemical Society. Meeting and published by . This book was released on 2004 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: All living things rely on the efficient storage, transduction, and use of energy. For example, all free energy used by biological systems originates from solar energy stored by photosynthesis and its effective use relies on its transformation from one form to the other. In this volume, leaders in the fields of computational modeling of electron transfer, proton transfer, proton-couples electron transfer, and energy transduction present new methods for simulating bioenergetic processes and summarize applications to proteins, including the photosynthetic reaction center, bacteriorhodopsin, and cytochrome c.

Biology for AP ® Courses

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Publisher :
ISBN 13 : 9781947172401
Total Pages : 1923 pages
Book Rating : 4.1/5 (724 download)

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Book Synopsis Biology for AP ® Courses by : Julianne Zedalis

Download or read book Biology for AP ® Courses written by Julianne Zedalis and published by . This book was released on 2017-10-16 with total page 1923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.

Oxford Desk Reference: Critical Care

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Publisher : OUP Oxford
ISBN 13 : 0191551996
Total Pages : 632 pages
Book Rating : 4.1/5 (915 download)

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Book Synopsis Oxford Desk Reference: Critical Care by : Carl Waldmann

Download or read book Oxford Desk Reference: Critical Care written by Carl Waldmann and published by OUP Oxford. This book was released on 2008-11-27 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical care medicine is an evolving speciality in which the amount of available information is growing daily and spread across a myriad of books, journals and websites. This essential guide brings together this information in an easy-to-use format. Up-to-date, relevant, and evidence-based information on the management of the critically ill is combined in one resource, ideal for the use of Intensive Care Units, High Dependency Units, acute medical or surgical wards, Accident and Emergency departments and operating theatres. The book is designed such that each subject will form a self-contained topic in its own right, laid out across two or four pages to facilitate the key aim of rapid and easy access to information. This makes the information included simple to find, read and absorb, so that the book can be consulted in the clinic or ward setting for information on the optimum management of a particular condition. With chapters written by internationally renowned critical care specialists and edited by the three of the leading figures in UK Critical Care, this book should be an essential resource for all critical care physicians.

Revolutions: a Very Short Introduction

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Publisher : Oxford University Press
ISBN 13 : 0197666302
Total Pages : 177 pages
Book Rating : 4.1/5 (976 download)

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Book Synopsis Revolutions: a Very Short Introduction by : Jack A. Goldstone

Download or read book Revolutions: a Very Short Introduction written by Jack A. Goldstone and published by Oxford University Press. This book was released on 2023 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In the 20th and 21st century revolutions have become more urban, often less violent, but also more frequent and more transformative of the international order. Whether it is the revolutions against Communism in Eastern Europe and the USSR; the "color revolutions" across Asia, Europe and North Africa; or the religious revolutions in Iran, Afghanistan, and Syria; today's revolutions are quite different from those of the past. Modern theories of revolution have therefore replaced the older class-based theories with more varied, dynamic, and contingent models of social and political change. This new edition updates the history of revolutions, from Classical Greece and Rome to the Revolution of Dignity in the Ukraine, with attention to the changing types and outcomes of revolutionary struggles. It also presents the latest advances in the theory of revolutions, including the issues of revolutionary waves, revolutionary leadership, international influences, and the likelihood of revolutions to come. This volume provides a brief but comprehensive introduction to the nature of revolutions and their role in global history"--