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Author : Kent Douglas Campbell
Publisher :
ISBN 13 :
Total Pages : 90 pages
Book Rating : 4.:/5 (973 download)
Download or read book A Novel Method for Synthesis of Indole Compounds written by Kent Douglas Campbell and published by . This book was released on 1977 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Richard J. Sundberg
Publisher : Elsevier
ISBN 13 : 0080534619
Total Pages : 193 pages
Book Rating : 4.0/5 (85 download)
Download or read book Indoles written by Richard J. Sundberg and published by Elsevier. This book was released on 1996-05-28 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Indoles continue to be of great interest to the pharmaceutical industry and at the current time several thousand specific new derivatives are reported annually. Research has been driven by the wide range of indole derivatives which occur in nature and through the biological activity of many indole derivatives, of both natural and synthetic origin.This book provides a systematic guide to the most useful and important reactions in the field for both synthesis and synthetic modification of the indole ring. While including the most recently developed and promising methods, it also updates informationavailable on classical methods to give the reader an up-to-date and comprehensive view of the subject. The methods are illustrated by procedures drawn from the literature and by tables including examples chosen to indicate both the scope of applicabilityand variations in methodology. The organization of the book is based on the retrosynthetic concept of identifying the bond(s) formed in the reaction, which in turn identifies potential starting materials. - Includes systematic summaries of the most important methods for the construction of indoles from aromatic precursors - Discusses methods for preparing indoles by annelation of pyrroles - Covers methods for adding or modifying substituent groups, including methods for introducing the tryptamine and tryptophan side-chainsExamines reduction/oxidation reactions that are specific for indoles - Considers use of cycloaddition reactions for synthetic elaboration of indoles
Author : Liang Guo
Publisher :
ISBN 13 :
Total Pages : 390 pages
Book Rating : 4.:/5 (252 download)
Download or read book Synthesis and Study of New Indole and Estrone Ru Complexes written by Liang Guo and published by . This book was released on 1991 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Yasamin Moazami
Publisher :
ISBN 13 :
Total Pages : 154 pages
Book Rating : 4.:/5 (841 download)
Download or read book Novel Methodology for the Synthesis of Substituted Indoles written by Yasamin Moazami and published by . This book was released on 2011 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Herein, a novel approach is reported of the synthesis of substituted indole derivatives that utilizes a lithiation reaction of a substituted JV-alkyl benzyl aniline to yield a dilithio intermediate, which is then trapped with an ester. The reaction sequence utilizes an internal cyclization and a subsequent dehydration, to generate a substituted indole.
Author : Karim Aboutayab
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (62 download)
Download or read book Novel Methods for the Synthesis of Functionalised Indoles written by Karim Aboutayab and published by . This book was released on 1995 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kuldeep Singh
Publisher : Notion Press
ISBN 13 :
Total Pages : 96 pages
Book Rating : 4.8/5 (852 download)
Download or read book Synthetic Methods of Indole Derivatives : Named Reactions used in the synthesis of Indole Derivatives written by Kuldeep Singh and published by Notion Press. This book was released on with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Indole is the foremost heterocyclic compound in the entire heterocyclic system. Some of the ring heterocyclics are formed when the benzene ring is fused to five or six-membered heterocyclic compounds at the second and third positions of the benzene ring. It may include indole, benzofuran, quinoline, isoquinoline. Indole plays an integral role in chemical, biological and pharmacological activities. Indole nuclei carry immense importance as it built proteins in the form of amino acid tryptophan and depicts the Skelton of indole alkaloids. Indole binds with high affinity with the multiple receptors. Due to its huge medical importance such as antimicrobial, antiproliferative, antiviral, antifungal, antioxidant, antidiabetic, antihistamine, anti-inflammatory, analgesic, anticancer, antitubercular, antihypertensive, antimalarial, anticholinesterase and many more indole is found to be invariably crucial to study. The medical importance of indole amuses researchers to synthesize diverse types of indole derivatives as it also flair some new therapeutic effects. Indole moiety is a subpart of radical scavengers are found commonly in the body. Indole not only has biological importance but also acquires so many industrial applications say dyes, flavor enhancers, agriculture etc. It also has a significant role in commodity markets.
Author : Richard J. Sundberg
Publisher : Academic Press
ISBN 13 : 9780126769456
Total Pages : 175 pages
Book Rating : 4.7/5 (694 download)
Download or read book Indoles written by Richard J. Sundberg and published by Academic Press. This book was released on 1996-07-16 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Indoles continue to be of great interest to the pharmaceutical industry and at the current time several thousand specific new derivatives are reported annually. Research has been driven by the wide range of indole derivatives which occur in nature and through the biological activity of many indole derivatives, of both natural and synthetic origin.This book provides a systematic guide to the most useful and important reactions in the field for both synthesis and synthetic modification of the indole ring. While including the most recently developed and promising methods, it also updates informationavailable on classical methods to give the reader an up-to-date and comprehensive view of the subject. The methods are illustrated by procedures drawn from the literature and by tables including examples chosen to indicate both the scope of applicabilityand variations in methodology. The organization of the book is based on the retrosynthetic concept of identifying the bond(s) formed in the reaction, which in turn identifies potential starting materials. Includes systematic summaries of the most important methods for the construction of indoles from aromatic precursors Discusses methods for preparing indoles by annelation of pyrroles Covers methods for adding or modifying substituent groups, including methods for introducing the tryptamine and tryptophan side-chainsExamines reduction/oxidation reactions that are specific for indoles Considers use of cycloaddition reactions for synthetic elaboration of indoles
Author : Gordon W. Gribble
Publisher : John Wiley & Sons
ISBN 13 : 0470512180
Total Pages : 704 pages
Book Rating : 4.4/5 (75 download)
Download or read book Indole Ring Synthesis written by Gordon W. Gribble and published by John Wiley & Sons. This book was released on 2016-08-08 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Of the myriad of heterocycles known to man, the indole ring stands foremost for its remarkably versatile chemistry, its enormous range of biological activities, and its ubiquity in the terrestrial and marine environments. The indole ring continues to be discovered in natural products and to be employed in man-made pharmaceuticals and other materials. Given the enormous resurgence in indole ring synthesis over the past decade — highlighted by the power of transition metal catalysis — this authoritative guide addresses the need for a comprehensive presentation of the myriad of methods for constructing the indole ring, from the ancient to the modern, and from the obscure to the well-known. Following presentation of the classic indole ring syntheses and many newer methods, coverage continues with indole ring syntheses via pyrroles, indolines, oxindoles, isatins, radical and photochemical reactions, aryne cycloadditions. This extensive volume concludes with the modern transition metal–catalyzed indole ring syntheses that utilize copper, palladium, rhodium, gold, ruthenium, platinum, and other metals to fashion the indole ring Indole Ring Synthesis is a comprehensive, authoritative and up-to-date guide to the synthesis of this important heterocycle for organic chemists, pharmaceutical researchers and those interested in the chemistry of natural products.
Author : Richard Sundberg
Publisher : Elsevier
ISBN 13 : 0323147860
Total Pages : 505 pages
Book Rating : 4.3/5 (231 download)
Download or read book The Chemistry of Indoles written by Richard Sundberg and published by Elsevier. This book was released on 2012-12-02 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Chemistry, Volume 18: The Chemistry of Indoles discusses the chemistry of indole derivatives. This book explores the potent biological activity of several indole derivatives and explains the structure of indole alkaloids. Organized into 10 chapters, this monograph starts with an overview of the most important types of reactions of the indole ring on a mechanical basis. This text then proceeds to review the methods of synthesizing indoles and describes the oxidations and rearrangements of indole derivatives. Other chapters explore the special features of the synthesis and reactivity of hydroxyindoles, acylindoles, and aminoindoles. This book discusses as well the properties of carboxyl groups, which is substituted on the benzenoid ring of the indole nucleus that is typical of aromatic carboxylic acids. The final chapter deals with the certain classes of indoles that are found in nature. Chemists, researchers, and readers interested in the chemistry of indoles will find this book extremely useful.
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Author : Angelique Natalia Cassandra Lotter
Publisher :
ISBN 13 :
Total Pages : 256 pages
Book Rating : 4.:/5 (775 download)
Download or read book A Novel Method for the Synthesis of Indolo[2,1-a]isoquinolines written by Angelique Natalia Cassandra Lotter and published by . This book was released on 2005 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Tomas Hudlicky
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 1032 pages
Book Rating : 4.X/5 (3 download)
Download or read book The Way of Synthesis written by Tomas Hudlicky and published by Wiley-VCH. This book was released on 2007-09-04 with total page 1032 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-colored textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of the most important total synthesis of the last 50 years with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, regardless of the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives and, what makes this textbook extraordinairy, with personal recollections of the chemists, who synthesized these fascinating compounds. With its attractive layout highlighting key parts and tactics using a second color, this is a useful tool for organic chemists, lecturers and students in chemistry, as well as those working in the chemical industry. "I think, as will many organic chemists, that the Hudlicky book will be the Bible of synthetic organic chemistry, the past, the present and the future. A hallmark publication." (Victor Snieckus)
Author : Stefan Bräse
Publisher : Royal Society of Chemistry
ISBN 13 : 1782620303
Total Pages : 486 pages
Book Rating : 4.7/5 (826 download)
Download or read book Privileged Scaffolds in Medicinal Chemistry written by Stefan Bräse and published by Royal Society of Chemistry. This book was released on 2015-11-20 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the various classes of privileged scaffolds and covers the history of their discovery and use.
Author : Chandra Sekhar
Publisher : Mohammed Abdul Malik
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.2/5 (241 download)
Download or read book Visible Light-Driven Fused Indole Synthesis written by Chandra Sekhar and published by Mohammed Abdul Malik. This book was released on 2024-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Visible Light-Driven Fused Indole Synthesis, authored by Chandra Sekhar, is a comprehensive guide on the photochemical construction of fused indole frameworks using visible light photocatalysis. The book covers a wide range of topics related to organic chemistry, including synthetic methods, catalysis, green chemistry, organic photochemistry, and reaction mechanisms. One of the key focuses of the book is the synthesis of heterocyclic compounds, specifically indole derivatives, using visible light-driven photocatalysis. The author explains how this method of synthesis enables the use of sustainable chemistry, and offers a greener and more efficient alternative to traditional methods of chemical synthesis. The book delves into the molecular design and organic functionalization of various organic compounds, exploring the role of Lewis acids, photoredox catalysts, and other chemical intermediates in the process. It also covers the various energy transfer mechanisms involved in the process of photoactivation, and the use of carbonyl compounds and redox reactions in organic transformation. Additionally, the book explores the synthesis of aromatic compounds and N-heterocycles, and their potential use in the discovery of natural products and alkaloids. It also covers the excited state chemistry of organic materials, cascade reactions, and enantioselective synthesis using organic substrates. Overall, Visible Light-Driven Fused Indole Synthesis provides a valuable resource for researchers, students, and professionals in the field of synthetic organic chemistry, offering insight into the latest advances and techniques in the field.
Author : M. Matlosz
Publisher : Springer Science & Business Media
ISBN 13 : 3642567630
Total Pages : 584 pages
Book Rating : 4.6/5 (425 download)
Download or read book Microreaction Technology written by M. Matlosz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: IMRET 5 featured more than 80 oral and poster communications, covering the entire interdisciplinary field from design, production, modeling and characterization of microreactor devices to application of microstructured systems for production, energy and transportation, including many analytical and biological applications. A particularly strong topic was the investigation of the potential of microstructuring of reactors and systems components for process intensification. Perspectives of combining local, in situ, data acquisition with appropriate microstructuring of actuators and components within chemical and biological devices were explored in order to enhance process performance and facilitate process control.
Author :
Publisher : Elsevier
ISBN 13 : 0081026919
Total Pages : 4266 pages
Book Rating : 4.0/5 (81 download)
Download or read book Comprehensive Natural Products III written by and published by Elsevier. This book was released on 2020-07-22 with total page 4266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Natural Products III, Third Edition, Seven Volume Set updates and complements the previous two editions, including recent advances in cofactor chemistry, structural diversity of natural products and secondary metabolites, enzymes and enzyme mechanisms and new bioinformatics tools. Natural products research is a dynamic discipline at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids and enzymes. This book reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine and to stimulate new ideas among the established natural products community. Provides readers with an in-depth review of current natural products research and a critical insight into the future direction of the field Bridges the gap in knowledge by covering developments in the field since the second edition published in 2010 Split into 7 sections on key topics to allow students, researchers and professionals to find relevant information quickly and easily Ensures that the knowledge within is easily understood by and applicable to a large audience
Author : Oscar Klioze
Publisher :
ISBN 13 :
Total Pages : 154 pages
Book Rating : 4.:/5 (51 download)
Download or read book Synthesis of Indole Compounds written by Oscar Klioze and published by . This book was released on 1949 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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Author : Sello, Thato Saoeni
Publisher :
ISBN 13 :
Total Pages : 250 pages
Book Rating : 4.:/5 (775 download)
Download or read book A Novel Method for the Synthesis of Indolo[2,1-a]isoquinolines and Modelling Studies of 3-substitutes Oxindoles Against PfPK5 written by Sello, Thato Saoeni and published by . This book was released on 2008 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
