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Author : Yong Lu
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (144 download)
Download or read book A Computational Framework for the Analysis of Multi-species Microarray Data written by Yong Lu and published by . This book was released on 2008 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Altuna Akalin
Publisher : CRC Press
ISBN 13 : 1498781861
Total Pages : 463 pages
Book Rating : 4.4/5 (987 download)
Download or read book Computational Genomics with R written by Altuna Akalin and published by CRC Press. This book was released on 2020-12-16 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Genomics with R provides a starting point for beginners in genomic data analysis and also guides more advanced practitioners to sophisticated data analysis techniques in genomics. The book covers topics from R programming, to machine learning and statistics, to the latest genomic data analysis techniques. The text provides accessible information and explanations, always with the genomics context in the background. This also contains practical and well-documented examples in R so readers can analyze their data by simply reusing the code presented. As the field of computational genomics is interdisciplinary, it requires different starting points for people with different backgrounds. For example, a biologist might skip sections on basic genome biology and start with R programming, whereas a computer scientist might want to start with genome biology. After reading: You will have the basics of R and be able to dive right into specialized uses of R for computational genomics such as using Bioconductor packages. You will be familiar with statistics, supervised and unsupervised learning techniques that are important in data modeling, and exploratory analysis of high-dimensional data. You will understand genomic intervals and operations on them that are used for tasks such as aligned read counting and genomic feature annotation. You will know the basics of processing and quality checking high-throughput sequencing data. You will be able to do sequence analysis, such as calculating GC content for parts of a genome or finding transcription factor binding sites. You will know about visualization techniques used in genomics, such as heatmaps, meta-gene plots, and genomic track visualization. You will be familiar with analysis of different high-throughput sequencing data sets, such as RNA-seq, ChIP-seq, and BS-seq. You will know basic techniques for integrating and interpreting multi-omics datasets. Altuna Akalin is a group leader and head of the Bioinformatics and Omics Data Science Platform at the Berlin Institute of Medical Systems Biology, Max Delbrück Center, Berlin. He has been developing computational methods for analyzing and integrating large-scale genomics data sets since 2002. He has published an extensive body of work in this area. The framework for this book grew out of the yearly computational genomics courses he has been organizing and teaching since 2015.
Author : Guo-Cheng Yuan
Publisher : Humana Press
ISBN 13 : 9781493990566
Total Pages : 271 pages
Book Rating : 4.9/5 (95 download)
Download or read book Computational Methods for Single-Cell Data Analysis written by Guo-Cheng Yuan and published by Humana Press. This book was released on 2019-02-14 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book provides state-of-art computational approaches to further explore the exciting opportunities presented by single-cell technologies. Chapters each detail a computational toolbox aimed to overcome a specific challenge in single-cell analysis, such as data normalization, rare cell-type identification, and spatial transcriptomics analysis, all with a focus on hands-on implementation of computational methods for analyzing experimental data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Methods for Single-Cell Data Analysis aims to cover a wide range of tasks and serves as a vital handbook for single-cell data analysis.
Author : Anand R. Asthagiri
Publisher : Academic Press
ISBN 13 : 0123884039
Total Pages : 427 pages
Book Rating : 4.1/5 (238 download)
Download or read book Computational Methods in Cell Biology written by Anand R. Asthagiri and published by Academic Press. This book was released on 2012-04-13 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational methods are playing an ever increasing role in cell biology. This volume of Methods in Cell Biology focuses on Computational Methods in Cell Biology and consists of two parts: (1) data extraction and analysis to distill models and mechanisms, and (2) developing and simulating models to make predictions and testable hypotheses. Focuses on computational methods in cell biology Split into 2 parts--data extraction and analysis to distill models and mechanisms, and developing and simulating models to make predictions and testable hypotheses Emphasizes the intimate and necessary connection with interpreting experimental data and proposing the next hypothesis and experiment
Author : Haixu Tang
Publisher : Springer Nature
ISBN 13 : 3031291190
Total Pages : 297 pages
Book Rating : 4.0/5 (312 download)
Download or read book Research in Computational Molecular Biology written by Haixu Tang and published by Springer Nature. This book was released on 2023-04-02 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 27th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2023, held in Istanbul, Turkey, during April 16–19, 2023. The 11 regular and 33 short papers presented in this book were carefully reviewed and selected from 188 submissions. The papers report on original research in all areas of computational molecular biology and bioinformatics.
Author : American Association for Cancer Research (AACR)
Publisher : CTI Meeting Technology
ISBN 13 :
Total Pages : 1518 pages
Book Rating : 4./5 ( download)
Download or read book AACR 2016: Abstracts 2697-5293 written by American Association for Cancer Research (AACR) and published by CTI Meeting Technology. This book was released on 2016-03-28 with total page 1518 pages. Available in PDF, EPUB and Kindle. Book excerpt: The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 2697-5293 presented on April 19-20, 2016, at the AACR Annual Meeting.
Author : Ronald Trent
Publisher : Humana
ISBN 13 : 9781493947003
Total Pages : 0 pages
Book Rating : 4.9/5 (47 download)
Download or read book Clinical Bioinformatics written by Ronald Trent and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Clinical Bioinformatics, Second Edition, leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance. Recent developments in omics, such as increasingly sophisticated analytic platforms allowing changes in diagnostic strategies from the traditional focus on single or small number of analytes to what might be possible when large numbers or all analytes are measured, are now impacting patient care. Covering such topics as gene discovery, gene function (microarrays), DNA sequencing, online approaches and resources, and informatics in clinical practice, this volume concisely yet thoroughly explores this cutting-edge subject. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Clinical Bioinformatics, Second Edition serves as an ideal guide for scientists and health professionals working in genetics and genomics.
Author : Richard Durbin
Publisher : Cambridge University Press
ISBN 13 : 113945739X
Total Pages : 372 pages
Book Rating : 4.1/5 (394 download)
Download or read book Biological Sequence Analysis written by Richard Durbin and published by Cambridge University Press. This book was released on 1998-04-23 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.
Author : A.C. Telea
Publisher : BoD – Books on Demand
ISBN 13 : 9535101587
Total Pages : 295 pages
Book Rating : 4.5/5 (351 download)
Download or read book Reverse Engineering written by A.C. Telea and published by BoD – Books on Demand. This book was released on 2012-03-07 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reverse engineering encompasses a wide spectrum of activities aimed at extracting information on the function, structure, and behavior of man-made or natural artifacts. Increases in data sources, processing power, and improved data mining and processing algorithms have opened new fields of application for reverse engineering. In this book, we present twelve applications of reverse engineering in the software engineering, shape engineering, and medical and life sciences application domains. The book can serve as a guideline to practitioners in the above fields to the state-of-the-art in reverse engineering techniques, tools, and use-cases, as well as an overview of open challenges for reverse engineering researchers.
Author : Gary Hardiman
Publisher : MDPI
ISBN 13 : 3039287443
Total Pages : 202 pages
Book Rating : 4.0/5 (392 download)
Download or read book Systems Analytics and Integration of Big Omics Data written by Gary Hardiman and published by MDPI. This book was released on 2020-04-15 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: A “genotype" is essentially an organism's full hereditary information which is obtained from its parents. A "phenotype" is an organism's actual observed physical and behavioral properties. These may include traits such as morphology, size, height, eye color, metabolism, etc. One of the pressing challenges in computational and systems biology is genotype-to-phenotype prediction. This is challenging given the amount of data generated by modern Omics technologies. This “Big Data” is so large and complex that traditional data processing applications are not up to the task. Challenges arise in collection, analysis, mining, sharing, transfer, visualization, archiving, and integration of these data. In this Special Issue, there is a focus on the systems-level analysis of Omics data, recent developments in gene ontology annotation, and advances in biological pathways and network biology. The integration of Omics data with clinical and biomedical data using machine learning is explored. This Special Issue covers new methodologies in the context of gene–environment interactions, tissue-specific gene expression, and how external factors or host genetics impact the microbiome.
Author : Florian Markowetz
Publisher : Cambridge University Press
ISBN 13 : 131638098X
Total Pages : 287 pages
Book Rating : 4.3/5 (163 download)
Download or read book Systems Genetics written by Florian Markowetz and published by Cambridge University Press. This book was released on 2015-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies.
Author : Richard C. Deonier
Publisher : Springer Science & Business Media
ISBN 13 : 0387288074
Total Pages : 543 pages
Book Rating : 4.3/5 (872 download)
Download or read book Computational Genome Analysis written by Richard C. Deonier and published by Springer Science & Business Media. This book was released on 2005-12-27 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the foundations of key problems in computational molecular biology and bioinformatics. It focuses on computational and statistical principles applied to genomes, and introduces the mathematics and statistics that are crucial for understanding these applications. The book features a free download of the R software statistics package and the text provides great crossover material that is interesting and accessible to students in biology, mathematics, statistics and computer science. More than 100 illustrations and diagrams reinforce concepts and present key results from the primary literature. Exercises are given at the end of chapters.
Author : C. Bessiere
Publisher : IOS Press
ISBN 13 : 1614990980
Total Pages : 1056 pages
Book Rating : 4.6/5 (149 download)
Download or read book ECAI 2012 written by C. Bessiere and published by IOS Press. This book was released on 2012-08-15 with total page 1056 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial intelligence (AI) plays a vital part in the continued development of computer science and informatics. The AI applications employed in fields such as medicine, economics, linguistics, philosophy, psychology and logical analysis, not forgetting industry, are now indispensable for the effective functioning of a multitude of systems. This book presents the papers from the 20th biennial European Conference on Artificial Intelligence, ECAI 2012, held in Montpellier, France, in August 2012. The ECAI conference remains Europe's principal opportunity for researchers and practitioners of Artificial Intelligence to gather and to discuss the latest trends and challenges in all subfields of AI, as well as to demonstrate innovative applications and uses of advanced AI technology. ECAI 2012 featured four keynote speakers, an extensive workshop program, seven invited tutorials and the new Frontiers of Artificial Intelligence track, in which six invited speakers delivered perspective talks on particularly interesting new research results, directions and trends in Artificial Intelligence or in one of its related fields. The proceedings of PAIS 2012 and the System Demonstrations Track are also included in this volume, which will be of interest to all those wishing to keep abreast of the latest developments in the field of AI.
Author : Jojo Moolayil
Publisher : Apress
ISBN 13 : 1484242408
Total Pages : 192 pages
Book Rating : 4.4/5 (842 download)
Download or read book Learn Keras for Deep Neural Networks written by Jojo Moolayil and published by Apress. This book was released on 2018-12-07 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn, understand, and implement deep neural networks in a math- and programming-friendly approach using Keras and Python. The book focuses on an end-to-end approach to developing supervised learning algorithms in regression and classification with practical business-centric use-cases implemented in Keras. The overall book comprises three sections with two chapters in each section. The first section prepares you with all the necessary basics to get started in deep learning. Chapter 1 introduces you to the world of deep learning and its difference from machine learning, the choices of frameworks for deep learning, and the Keras ecosystem. You will cover a real-life business problem that can be solved by supervised learning algorithms with deep neural networks. You’ll tackle one use case for regression and another for classification leveraging popular Kaggle datasets. Later, you will see an interesting and challenging part of deep learning: hyperparameter tuning; helping you further improve your models when building robust deep learning applications. Finally, you’ll further hone your skills in deep learning and cover areas of active development and research in deep learning. At the end of Learn Keras for Deep Neural Networks, you will have a thorough understanding of deep learning principles and have practical hands-on experience in developing enterprise-grade deep learning solutions in Keras. What You’ll Learn Master fast-paced practical deep learning concepts with math- and programming-friendly abstractions. Design, develop, train, validate, and deploy deep neural networks using the Keras framework Use best practices for debugging and validating deep learning models Deploy and integrate deep learning as a service into a larger software service or product Extend deep learning principles into other popular frameworks Who This Book Is For Software engineers and data engineers with basic programming skills in any language and who are keen on exploring deep learning for a career move or an enterprise project.
Author : Robert Gentleman
Publisher : Springer Science & Business Media
ISBN 13 : 0387293620
Total Pages : 478 pages
Book Rating : 4.3/5 (872 download)
Download or read book Bioinformatics and Computational Biology Solutions Using R and Bioconductor written by Robert Gentleman and published by Springer Science & Business Media. This book was released on 2005-12-29 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: Full four-color book. Some of the editors created the Bioconductor project and Robert Gentleman is one of the two originators of R. All methods are illustrated with publicly available data, and a major section of the book is devoted to fully worked case studies. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.
Author : Chiara Romualdi
Publisher : Frontiers Media SA
ISBN 13 : 2889661512
Total Pages : 187 pages
Book Rating : 4.8/5 (896 download)
Download or read book Multi-omic Data Integration in Oncology written by Chiara Romualdi and published by Frontiers Media SA. This book was released on 2020-12-03 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : Nello Cristianini
Publisher : Cambridge University Press
ISBN 13 : 9780521856034
Total Pages : 200 pages
Book Rating : 4.8/5 (56 download)
Download or read book Introduction to Computational Genomics written by Nello Cristianini and published by Cambridge University Press. This book was released on 2006-12-14 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Where did SARS come from? Have we inherited genes from Neanderthals? How do plants use their internal clock? The genomic revolution in biology enables us to answer such questions. But the revolution would have been impossible without the support of powerful computational and statistical methods that enable us to exploit genomic data. Many universities are introducing courses to train the next generation of bioinformaticians: biologists fluent in mathematics and computer science, and data analysts familiar with biology. This readable and entertaining book, based on successful taught courses, provides a roadmap to navigate entry to this field. It guides the reader through key achievements of bioinformatics, using a hands-on approach. Statistical sequence analysis, sequence alignment, hidden Markov models, gene and motif finding and more, are introduced in a rigorous yet accessible way. A companion website provides the reader with Matlab-related software tools for reproducing the steps demonstrated in the book.
