Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 3

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Publisher : World Health Organization
ISBN 13 : 9240021264
Total Pages : 45 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 3 by : World Health Organization

Download or read book Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 3 written by World Health Organization and published by World Health Organization. This book was released on 2023-10-23 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt: Globally, there is growing recognition of foodborne diseases as a public health priority. From a public health perspective, foodborne diseases are largely preventable, and can be controlled through effective food safety systems that evaluate hazards along the food chain, from production to consumption. An integrated food chain surveillance system can detect and monitor foodborne bacteria, including antimicrobial resistant bacteria, throughout the food chain. Whole genome sequencing (WGS) has the potential to change how we detect and monitor microbial hazards in the food chain, as well as how we assess, investigate and manage food safety risks. It is anticipated that this new technology will help reduce the burden of foodborne diseases, given its advantages over previous low-resolution typing and detection methods. The purpose of this manual is to provide guidance on: - The capacities that need to be in place before WGS can be useful for foodborne disease surveillance and response; - The options for implementing WGS; and - How to implement WGS within existing surveillance and response systems. This module is about using WGS in routine surveillance of foodborne diseases. It is meant for countries experienced in laboratory-based surveillance of foodborne pathogens. WGS can be implemented where subtyping foodborne pathogens or replacing traditional typing methods is being considered. Routine surveillance includes outbreak detection, monitoring trends over time, and using WGS for AMR and virulence factor monitoring.

Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 1

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Author :
Publisher : World Health Organization
ISBN 13 : 9240021221
Total Pages : 78 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 1 by : World Health Organization

Download or read book Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 1 written by World Health Organization and published by World Health Organization. This book was released on 2023-10-19 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: Globally, there is growing recognition of foodborne diseases as a public health priority. From a public health perspective, foodborne diseases are largely preventable, and can be controlled through effective food safety systems that evaluate hazards along the food chain, from production to consumption. An integrated food chain surveillance system can detect and monitor foodborne bacteria, including antimicrobial resistant bacteria, throughout the food chain. Whole genome sequencing (WGS) has the potential to change how we detect and monitor microbial hazards in the food chain, as well as how we assess, investigate and manage food safety risks. It is anticipated that this new technology will help reduce the burden of foodborne diseases, given its advantages over previous low-resolution typing and detection methods. The purpose of this manual is to provide guidance on: - The capacities that need to be in place before WGS can be useful for foodborne disease surveillance and response, - The options for implementing WGS; and - How to implement WGS within existing surveillance and response systems. The present module introduces WGS and its relevance to foodborne diseases; it defines the minimum capacities needed before a country can implement WGS for outbreak investigations and routine surveillance; and includes a section to assist countries in selecting an option for implementing WGS within their existing surveillance and response system.

Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 2

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Author :
Publisher : World Health Organization
ISBN 13 : 9240021248
Total Pages : 70 pages
Book Rating : 4.2/5 (4 download)

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Book Synopsis Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 2 by : World Health Organization

Download or read book Whole genome sequencing as a tool to strengthen foodborne disease surveillance and response. Module 2 written by World Health Organization and published by World Health Organization. This book was released on 2023-10-19 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: Globally, there is growing recognition of foodborne diseases as a public health priority. From a public health perspective, foodborne diseases are largely preventable, and can be controlled through effective food safety systems that evaluate hazards along the food chain, from production to consumption. An integrated food chain surveillance system can detect and monitor foodborne bacteria, including antimicrobial resistant bacteria, throughout the food chain. Whole genome sequencing (WGS) has the potential to change how we detect and monitor microbial hazards in the food chain, as well as how we assess, investigate and manage food safety risks. It is anticipated that this new technology will help reduce the burden of foodborne diseases, given its advantages over previous low-resolution typing and detection methods. The purpose of this manual is to provide guidance on: - The capacities that need to be in place before WGS can be useful for foodborne disease surveillance and response; - The options for implementing WGS; and - How to implement WGS within existing surveillance and response systems. This module discusses how WGS can be used to support foodborne disease outbreak investigations. It is meant for countries in the initial stages of laboratory-based surveillance for selected foodborne pathogens. The module describes how WGS can be used in the investigation of outbreaks detected by existing surveillance systems.

Food Microbiology

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1837673705
Total Pages : 435 pages
Book Rating : 4.8/5 (376 download)

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Book Synopsis Food Microbiology by : Martin R Adams

Download or read book Food Microbiology written by Martin R Adams and published by Royal Society of Chemistry. This book was released on 2024-08-07 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Looking for a comprehensive textbook that covers the interaction between micro-organisms and food? Spoilage, foodborne illness, and fermentation. Food Microbiology has been the most popular textbook in this area since it was first published in 1995. Now in its fifth edition, the highly successful authors bring the book right up to date. Maintaining its general structure and philosophy to encompass modern food microbiology, this new edition provides updated and revised individual chapters and uses new examples to illustrate incidents. It covers the three main aspects of the interaction between micro-organisms and food and the positive and negative features that result. Attention is paid to the illustrations included and there is a discussion on the factors affecting the presence of micro-organisms in foods and their capacity to survive and grow. Finally, recent developments in procedures used to assay and control the microbiological quality of food and protect public health are reported. Thorough and accessible, this book is designed for students in the biological sciences, biotechnology, and food science, as well as a valuable resource for researchers, teachers, and practising food microbiologists.

Guidelines for Foodborne Disease Outbreak Response

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Publisher :
ISBN 13 :
Total Pages : 206 pages
Book Rating : 4.:/5 (9 download)

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Book Synopsis Guidelines for Foodborne Disease Outbreak Response by :

Download or read book Guidelines for Foodborne Disease Outbreak Response written by and published by . This book was released on 2009 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Foodborne Disease Outbreaks

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Publisher : World Health Organization
ISBN 13 : 9241547227
Total Pages : 157 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Foodborne Disease Outbreaks by : World Health Organization

Download or read book Foodborne Disease Outbreaks written by World Health Organization and published by World Health Organization. This book was released on 2008 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: "These guidelines have been written for public health practitioners, food and health inspectors, district and national medical officers, laboratory personnel and others who may undertake or participate in the investigation and control of foodborne disease outbreaks."--P. 4 of cover.

Management of Legionella in Water Systems

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Publisher : National Academies Press
ISBN 13 : 030949382X
Total Pages : 291 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Management of Legionella in Water Systems by : National Academies of Sciences, Engineering, and Medicine

Download or read book Management of Legionella in Water Systems written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-02-20 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Legionnaires' disease, a pneumonia caused by the Legionella bacterium, is the leading cause of reported waterborne disease outbreaks in the United States. Legionella occur naturally in water from many different environmental sources, but grow rapidly in the warm, stagnant conditions that can be found in engineered water systems such as cooling towers, building plumbing, and hot tubs. Humans are primarily exposed to Legionella through inhalation of contaminated aerosols into the respiratory system. Legionnaires' disease can be fatal, with between 3 and 33 percent of Legionella infections leading to death, and studies show the incidence of Legionnaires' disease in the United States increased five-fold from 2000 to 2017. Management of Legionella in Water Systems reviews the state of science on Legionella contamination of water systems, specifically the ecology and diagnosis. This report explores the process of transmission via water systems, quantification, prevention and control, and policy and training issues that affect the incidence of Legionnaires' disease. It also analyzes existing knowledge gaps and recommends research priorities moving forward.

Game Changer-Next Generation Sequencing and Its Impact on Food Microbiology

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889454630
Total Pages : 302 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Game Changer-Next Generation Sequencing and Its Impact on Food Microbiology by : Jennifer Ronholm

Download or read book Game Changer-Next Generation Sequencing and Its Impact on Food Microbiology written by Jennifer Ronholm and published by Frontiers Media SA. This book was released on 2018-04-26 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in next-generation sequencing technologies (NGS) are revolutionizing the field of food microbiology. Microbial whole genome sequencing (WGS) can provide identification, characterization, and subtyping of pathogens for epidemiological investigations at a level of precision previously not possible. This allows for connections and source attribution to be inferred between related isolates that may be overlooked by traditional techniques. The archiving and global sharing of genome sequences allow for retrospective analysis of virulence genes, antimicrobial resistance markers, mobile genetic elements and other novel genes. The advent of high-throughput 16S rRNA amplicon sequencing, in combination with the advantages offered by massively parallel second-generation sequencing for metagenomics, enable intensive studies on the microbiomes of food products and the impact of foods on the human microbiome. These studies may one day lead to the development of reliable culture-independent methods for food monitoring and surveillance. Similarly, RNA-seq has provided insights into the transcriptomes and hence the behaviour of bacterial pathogens in food, food processing environments, and in interaction with the host at a resolution previously not achieved through the use of microarrays and/or RT-PCR. The vast un-tapped potential applications of NGS along with its rapidly declining costs, give this technology the ability to contribute significantly to consumer protection, global trade facilitation, and increased food safety and security. Despite the rapid advances, challenges remain. How will NGS data be incorporated into our existing global food safety infrastructure? How will massive NGS data be stored and shared globally? What bioinformatics solutions will be used to analyse and optimise these large data sets? This Research Topic discusses recent advances in the field of food microbiology made possible through the use of NGS.

Equity, Social Determinants and Public Health Programmes

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Author :
Publisher : World Health Organization
ISBN 13 : 9241563974
Total Pages : 302 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Equity, Social Determinants and Public Health Programmes by : World Health Organization

Download or read book Equity, Social Determinants and Public Health Programmes written by World Health Organization and published by World Health Organization. This book was released on 2010 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. Introduction and methods of work.-- 2. Alcohol: equity and social determinants.-- 3. Cardiovascular disease: equity and social determinants.-- 4. Health and nutrition of children: equity and social determinants.-- 5. Diabetes: equity and social determinants.-- 6. Food safety: equity and social determinants.-- 7. Mental disorders: equity and social determinants.-- 8. Neglected tropical diseases: equity and social determinants.-- 9. Oral health: equity and social determinants.-- 10. Unintended pregnancy and pregnancy outcome: equity and social determinants.-- 11. Tobacco use: equity and social determinants.-- 12. Tuberculosis: the role of risk factors and social determinants.-- 13. Violence and unintentional injury: equity and social determinants.-- 14. Synergy for equity.

WHO Global Strategy for Food Safety

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Publisher :
ISBN 13 : 9789241545747
Total Pages : 26 pages
Book Rating : 4.5/5 (457 download)

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Book Synopsis WHO Global Strategy for Food Safety by : WHO. Food Safety Programme

Download or read book WHO Global Strategy for Food Safety written by WHO. Food Safety Programme and published by . This book was released on 2002 with total page 26 pages. Available in PDF, EPUB and Kindle. Book excerpt: Foodborne diseases takes a major toll on health. Thousands of millions of people fall ill and many die as a result of eating unsafe food. Deeply concerned by this a resolution was adopted by WHO and its Member States to recognize fod safety as an essential public health function and to develop a Global Strategy for reducing the burden of foodborne diseases.

Communicable Disease Control in Emergencies

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Publisher : World Health Organization
ISBN 13 : 9789241546164
Total Pages : 316 pages
Book Rating : 4.5/5 (461 download)

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Book Synopsis Communicable Disease Control in Emergencies by : World Health Organization

Download or read book Communicable Disease Control in Emergencies written by World Health Organization and published by World Health Organization. This book was released on 2005 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This field manual is intended to help health professionals and public health coordinators working in emergency situations prevent, detect and control the major communicable diseases encountered by affected populations. The manual is the result of collaboration among a number of WHO departments and several external partner agencies in reviewing existing guidelines on communicable disease control and adapting them to emergency situations. The manual deals with the fundamental principles of communicable disease control in emergencies, which are: Rapid assessment to identify the communicable disease threats faced by the emergency-affected population, including those with epidemic potential, and define the health status of the population by conducting a rapid assessment; Prevention to prevent communicable disease by maintaining a healthy physical environment and good general living conditions; Surveillance to set up or strengthen disease surveillance system with an early warning mechanism to ensure the early reporting of cases to monitor disease trends, and to facilitate prompt detection and response to outbreaks; outbreak control to ensure outbreaks are rapidly detected and controlled through adequate preparedness (i.e. stockpiles, standard treatment protocols and staff training) and rapid response (i.e.confirmation, investigation and implementation of control measures); and disease management to diagnose and treat cases promptly with trained staff using effective treatment and standard protocols at all health facilities.

Investing to Overcome the Global Impact of Neglected Tropical Diseases

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Publisher : World Health Organization
ISBN 13 : 9241564865
Total Pages : 211 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Investing to Overcome the Global Impact of Neglected Tropical Diseases by : World Health Organization

Download or read book Investing to Overcome the Global Impact of Neglected Tropical Diseases written by World Health Organization and published by World Health Organization. This book was released on 2015-08-05 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.

Guidelines for Drinking-water Quality

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Publisher : World Health Organization
ISBN 13 : 9789241545037
Total Pages : 260 pages
Book Rating : 4.5/5 (45 download)

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Book Synopsis Guidelines for Drinking-water Quality by : World Health Organization

Download or read book Guidelines for Drinking-water Quality written by World Health Organization and published by World Health Organization. This book was released on 1993 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes the methods used in the surveillance of drinking water quality in the light of the special problems of small-community supplies, particularly in developing countries, and outlines the strategies necessary to ensure that surveillance is effective.

Foodborne Microbial Pathogens

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Publisher : Springer Science & Business Media
ISBN 13 : 0387745378
Total Pages : 290 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Foodborne Microbial Pathogens by : Arun Bhunia

Download or read book Foodborne Microbial Pathogens written by Arun Bhunia and published by Springer Science & Business Media. This book was released on 2007-11-22 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: At last, here is a graduate-level textbook that focuses on the very latest information on the molecular and cellular mechanism of several major foodborne bacterial pathogens. For the first time in the field, this book makes the link between foodborne illness and immunology. It also covers virulence genes and their regulation in the host or the food environment, pathogenicity testing models, clinical symptoms and prevention and control strategies. Unlike other textbooks this one also covers the host/parasite interaction to a level where readers have a real appreciation of the disease mechanism. It is imperative that we acquire a better understanding of foodborne pathogens. And this is what this brilliant and timely contribution to the subject offers.

New Frontiers of Biostatistics and Bioinformatics

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Publisher : Springer
ISBN 13 : 3319993895
Total Pages : 473 pages
Book Rating : 4.3/5 (199 download)

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Book Synopsis New Frontiers of Biostatistics and Bioinformatics by : Yichuan Zhao

Download or read book New Frontiers of Biostatistics and Bioinformatics written by Yichuan Zhao and published by Springer. This book was released on 2018-12-05 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is comprised of presentations delivered at the 5th Workshop on Biostatistics and Bioinformatics held in Atlanta on May 5-7, 2017. Featuring twenty-two selected papers from the workshop, this book showcases the most current advances in the field, presenting new methods, theories, and case applications at the frontiers of biostatistics, bioinformatics, and interdisciplinary areas. Biostatistics and bioinformatics have been playing a key role in statistics and other scientific research fields in recent years. The goal of the 5th Workshop on Biostatistics and Bioinformatics was to stimulate research, foster interaction among researchers in field, and offer opportunities for learning and facilitating research collaborations in the era of big data. The resulting volume offers timely insights for researchers, students, and industry practitioners.

A Tale of Three Next Generation Sequencing Platforms

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Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781515216209
Total Pages : 42 pages
Book Rating : 4.2/5 (162 download)

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Book Synopsis A Tale of Three Next Generation Sequencing Platforms by : Applied Research Press

Download or read book A Tale of Three Next Generation Sequencing Platforms written by Applied Research Press and published by Createspace Independent Publishing Platform. This book was released on 2015-07-24 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt: Next generation sequencing (NGS) technology has revolutionized genomic and genetic research. The pace of change in this area is rapid with three major new sequencing platforms having been released in 2011: Ion Torrent's PGM, Pacific Biosciences' RS and the Illumina MiSeq. Here we compare the results obtained with those platforms to the performance of the Illumina HiSeq, the current market leader. In order to compare these platforms, and get sufficient coverage depth to allow meaningful analysis, we have sequenced a set of 4 microbial genomes with mean GC content ranging from 19.3 to 67.7%. Together, these represent a comprehensive range of genome content. Here we report our analysis of that sequence data in terms of coverage distribution, bias, GC distribution, variant detection and accuracy. All three fast turnaround sequencers evaluated here were able to generate usable sequence. However there are key differences between the quality of that data and the applications it will support. Proceeds from the sale of this book go to the support of an elderly disabled person.

Framework for a Public Health Emergency Operations Centre

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Publisher :
ISBN 13 : 9789241565134
Total Pages : 0 pages
Book Rating : 4.5/5 (651 download)

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Book Synopsis Framework for a Public Health Emergency Operations Centre by : World Health Organization

Download or read book Framework for a Public Health Emergency Operations Centre written by World Health Organization and published by . This book was released on 2015-12-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Framework for a Public Health Emergency Operations Centre (PHEOC framework) document is intended to be used by practitioners of public health; health policy makers; and authorities and agencies responsible for managing emergencies, incidents, or events where the health of populations is at risk. This document provides high-level methodical guidance for designing, developing, and strengthening of public health emergency operations centers. This interim document outlines the key concepts and essential requirements for developing and managing a public health EOC (PHEOC). The overall approach is generic and based on widely acknowledged elements of all-hazards emergency management. It provides an outline for developing and managing a PHEOC to achieve a goal-oriented response to public health emergencies and unity of effort among response agencies. The document will be revised as necessary. Practical guidance on specific aspects of the PHEOC framework will be developed and published separately. A public health emergency is here defined as an occurrence, or imminent threat, of an illness or health condition that poses a substantial risk of a significant number of human fatalities, injuries or permanent or long-term disability. Public health emergencies can result from a wide range of hazards and complex emergencies. Experience has shown that timely implementation of an EOC provides an essential platform for the effective management of public health emergencies. Public health emergencies involve increased incidence of illness, injury and/or death and require special measures to address increased morbidity, mortality and interruption of essential health services. For such emergencies, a multi-agency, multi-jurisdictional response is often required, working with the national disaster management organization. When normal resources and capacities are exceeded, support from outside the affected areas will also be required. External assistance could include national, cross-border, regional or international resources.