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Author : Chung-Yui Betty Li Tai
Publisher :
ISBN 13 :
Total Pages : 370 pages
Book Rating : 4.:/5 (12 download)
Download or read book Weak Electrolyte Transport Across Gastrointestinal Epithelia written by Chung-Yui Betty Li Tai and published by . This book was released on 1983 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Richard Maynard Case
Publisher : Raven Press (ID)
ISBN 13 :
Total Pages : 344 pages
Book Rating : 4.3/5 (91 download)
Download or read book Electrolyte and Water Transport Across Gastrointestinal Epithelia written by Richard Maynard Case and published by Raven Press (ID). This book was released on 1982 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mrinalin Rao
Publisher : Biota Publishing
ISBN 13 : 1615041575
Total Pages : 118 pages
Book Rating : 4.6/5 (15 download)
Download or read book Intestinal Water and Electrolyte Transport in Health and Disease written by Mrinalin Rao and published by Biota Publishing. This book was released on 2012-01-12 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: The unique architecture and physiology of the mammalian intestine, together with a tightly coordinated regulatory system, allows for the handling and absorption of as much as 9 L of fluid a day with 98% or greater efficiency. Advances in the past 40 years have made inroads into revealing the intricacies and interplay of numerous ion transporters and their modulators that are responsible for intestinal electrolyte and water transport. Studies of two devastating diseases, the virulent infectious disease cholera and the autosomal recessive disease cystic fibrosis, were largely responsible for this information explosion. These advances have been critical in the development of new therapeutic strategies to combat life-threatening diseases of varying etiologies ranging from enteric infections to cystic fibrosis and inflammatory bowel diseases. Yet, the story is far from complete, and progress needs to continue on translating information gained from reductionistic cell and tissue culture models, in vivo models, and ultimately human studies and on improving therapeutic approaches. This book reviews the current status of our knowledge of fluid transport across the intestine, including the complexities of transcellular and paracellular ion transport down the length of the intestine and how aberrations of normal physiological processes lead to disease. Table of Contents: Overview / Epithelial Cell and Tissue Architecture / Principles of Transepithelial Electrolyte and Water Movement / Intestinal Architecture and Electrolyte Transport / Electrolyte Transporters--Pumps, Carriers, and Channels / Water Transport / Regulation / Intestinal Disorders and Advances Toward Better Treatment of Intestinal Disorders / Conclusion / References
Author : Daniel K. Podolsky
Publisher : John Wiley & Sons
ISBN 13 : 1118512111
Total Pages : 16819 pages
Book Rating : 4.1/5 (185 download)
Download or read book Yamada's Textbook of Gastroenterology written by Daniel K. Podolsky and published by John Wiley & Sons. This book was released on 2015-10-22 with total page 16819 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seit 20 Jahren ist Yamada's Textbook of Gastroenterology das umfassendste und weltweit anerkannte Lehrwerk für das Fachgebiet und vereint in Form einer Enzyklopädie die wissenschaftlichen Grundlagen von Magen-Darm- und Lebererkrankungen mit den neuesten klinischen Erkenntnissen, vor allem Entwicklungen in den Bereichen Diagnose und Therapie. Zu dem Herausgeberteam unter der Leitung von Tachi Yamada, einer der weltweit führenden Forscher des Fachgebiets, gehörten schon immer herausragende Namen. Gleiches gilt für die Autoren vieler Beiträge, die zu den Experten ihres Fachbereichs gehören. Mit dem neuen Chefherausgeber Dan Podolsky, Professor für Innere Medizin an dem Southwestern Medical Center der University of Texas, wurde die 6. Auflage dieses führenden Lehrbuchs aktualisiert und in vielerlei Hinsicht verbessert - Jetzt beim Kauf der Printversion mit kostenlosem Zugriff auf die digitale Ausgabe mit umfassenden Suchfunktionen. - Einheitliche Darstellung der einzelnen Themenabschnitte, unterteilt in wissenschaftliche Grundlagen, Krankheiten und deren Symptome, und damit eine Vereinheitlichung in Aufbau, Inhalt und Länge. - Neuer Abschnitt "Principles of Clinical Gastroenterology" mit Schwerpunkt auf klinische Aspekte. In 14 Kapiteln wird auf die jeweiligen Krankheitssymptome eingegangen. Ärzte können so ihre Patienten in der Klinik noch besser beurteilen und behandeln. - Wichtige Themen werden noch ausführlicher erläutert (autoimmune Pankreatitis, fäkale Biomarker, Genetik, chronisch-entzündliche Darmerkrankungen, systemische IgG4-assoziierte Erkrankungen, Morbus Crohn, Colitis ulcerosa und eosinophile Ösophagitis). - Podcasts international führender Experten zu aktuellen Themen. - Stärkerer Schwerpunkt auf klinische Studien/Versuchsreihen, evidenzbasierte Praxis, Richtlinien von Fachverbänden und Regierungsstellen. - Verweise auf Online-Referenzwerke, Hyperlinks zu Pubmed/CrossRef. Die wichtigsten Verweise sind weiterhin in der Printversion enthalten. - Noch internationaler und global: Neben den führenden Experten aus Nordamerika kommen renommierte Fachärzte aus Europa und Asien zu Wort. Yamada's Textbook of Gastroenterology ist das umfassende Standardwerk der Gastroenterologie. Die 6. Auflage orientiert sich noch stärker am Klinikalltag, ist aufgrund der Fülle an Informationen zu wissenschaftlichen Grundlagen nach wie vor Marktführer und gleichzeitig ein herausragendes Referenzwerk zum klinischen Management von Erkrankungen des Magen-Darm-Trakts. Jetzt noch besser: Kostenloser Online-Zugang zu allen Inhalten der Printausgabe mit weitreichenden Suchfunktionen. Genau das Richtige für Gastroenterologen, ob erfahrener Praktiker oder Berufsanfänger.
Author : Alex Avdeef
Publisher : John Wiley & Sons
ISBN 13 : 1118286030
Total Pages : 741 pages
Book Rating : 4.1/5 (182 download)
Download or read book Absorption and Drug Development written by Alex Avdeef and published by John Wiley & Sons. This book was released on 2012-04-11 with total page 741 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains how to perform and analyze the results of the latest physicochemical methods With this book as their guide, readers have access to all the current information needed to thoroughly investigate and accurately determine a compound's pharmaceutical properties and their effects on drug absorption. The book emphasizes oral absorption, explaining all the physicochemical methods used today to analyze drug candidates. Moreover, the author provides expert guidance to help readers analyze the results of their studies in order to select the most promising drug candidates. This Second Edition has been thoroughly updated and revised, incorporating all the latest research findings, methods, and resources, including: Descriptions and applications of new PAMPA models, drawing on more than thirty papers published by the author's research group Two new chapters examining permeability and Caco-2/MDCK and permeability and the blood-brain barrier Expanded information and methods to support pKa determination New examples explaining the treatment of practically insoluble test compounds Additional case studies demonstrating the use of the latest physicochemical techniques New, revised, and expanded database tables throughout the book Well over 200 drawings help readers better understand difficult concepts and provide a visual guide to complex procedures. In addition, over 800 references serve as a gateway to the primary literature in the field, facilitating further research into all the topics covered in the book. This Second Edition is recommended as a reference for researchers in pharmaceutical R&D as well as in agrochemical, environmental, and other related areas of research. It is also recommended as a supplemental text for graduate courses in pharmaceutics.
Author : Thomas E. Andreoli
Publisher : Springer Science & Business Media
ISBN 13 : 1461320976
Total Pages : 1062 pages
Book Rating : 4.4/5 (613 download)
Download or read book Physiology of Membrane Disorders written by Thomas E. Andreoli and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 1062 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Physiology of Membrane Disorders represents an extensive revision and a considerable expansion of the first edition . Yet the purpose ofthe second edition is identical to that of its predecessor, namely, to provide a rational analysis of membrane transport processes in individual membranes, cells, tissues, and organs, which in tum serves as a frame of reference for rationalizing disorders in which derangements of membrane transport processes playa cardinal role in the clinical expression of disease. As in the first edition, this book is divided into a number of individual, but closely related, sections. Part V represents a new section where the problem of transport across epithelia is treated in some detail. Finally, Part VI, which analyzes clinical derangements, has been enlarged appreciably. THE EDITORS xi Preface to the First Edition The purpose of this book is to provide the reader with a rational frame of reference for assessing the pa thophysiology of those disorders in which derangements of membrane transport processes are a major factor responsible for the clinical manifestations of disease. In the present context, we use the term "membrane transport to refer to those molecular processes whose cardinal function, broadly speaking, is processes" in a catholic sense, the vectorial transfer of molecules-either individually or as ensembles-across biological interfaces, the latter including those interfaces which separate different intracellular compartments, the cellular and extracellular com partments, and secreted fluids-such as glomerular filtrate-and extracellular fluids.
Author : M. Gilles-Baillien
Publisher : Springer Science & Business Media
ISBN 13 : 3642691099
Total Pages : 384 pages
Book Rating : 4.6/5 (426 download)
Download or read book Intestinal Transport written by M. Gilles-Baillien and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this symposium was to provide a framework for fruitful discussion on intestinal transport, not only for advanced scientists but also for younger people starting in this field of research. Invited lectures, communications and poster presentations were focused on four central themes, all treating the prop erties of the sole intestinal epithelium, deliberately leaving aside problems dealing with more integrative functions of the whole intestine. The importance of motility or blood circulation, for instance, is certainly capital in the overall intestinal function, but these aspects by themselves deserve another meeting. This volume has compiled the manuscripts of the invited lectures which sub stantially comprised the four sessions of the Symposium. Part 1 is designed to emphasize actual knowledge of the transport of water, inorganic as well as organic ions and molecules across the isolated intestinal epithelium. An enormous wave of investigations has emerged from studies per formed with "Ussing chambers", which roused interest in studies on absorption mechanisms and subsequently on secretory processes. This has triggered off a trend to research on isolated cells as absorption and secretion are the main func tion of the different cell types constituting the intestinal epithelium. In this first session not only the importance of the parallel arrangement of these different cellular entities is stressed, but also the role played by the paracellular route.
Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642695086
Total Pages : 600 pages
Book Rating : 4.6/5 (426 download)
Download or read book Pharmacology of Intestinal Permeation II written by and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: The intestine, particularly the small bowel, represents a large surface (in the adult 2 human approximately 200 m ) through which the body is exposed to its environ ment. A vigorous substrate exchange takes place across this large surface: nutrients and xenobiotics are absorbed from the lumen into the bloodstream or the lymph, and simultaneously, the same types of substrate pass back into the lumen. The luminal surface of the intestine is lined with a "leaky" epithelium, thus the passage of the substrates, in either direction, proceeds via both transcellular and intercellular routes. Simple and carrier-mediated diffusion, active transport, pinocytosis, phagocytosis and persorption are all involved in this passage across the intestinal wall. The term "intestinal permeation" refers to the process of passage of various substances across the gut wall, either from the lumen into the blood or lymph, or in the opposite direction. "Permeability" is the condition of the gut which governs the rate of this complex two-way passage. The pharmacologist's interest in the problem of intestinal permeation is twofold: on the one hand, this process determines the bioavailability of drugs and contributes significantly to the pharmacokinetics and toxicokinetics of xeno biotics; on the other hand, the pharmacodynamic effects of many drugs are manifested in a signigicant alteration of the physiological process of intestinal permeation.
Author : Po Sing Leung
Publisher : Springer Science & Business
ISBN 13 : 9401787719
Total Pages : 370 pages
Book Rating : 4.4/5 (17 download)
Download or read book The Gastrointestinal System written by Po Sing Leung and published by Springer Science & Business. This book was released on 2014-04-29 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gastrointestinal (GI) physiology is a fundamental subject that is indispensable not only for undergraduate but also for graduate courses. The audience include, but are not limited to, medical, pharmacy, nursing, human biology, Chinese medicine, and science students, as well as other health-related subject students. The overall objectives of this textbook are to present basic concepts and principles of GI physiology and, more importantly, to convey an understanding of how to apply this knowledge to abnormal GI physiology in the clinical context. As such, the basic knowledge of GI physiology and its application in the form of clinical case studies should be grasped, which are critical for professional examinations and bedside, as well as for general practice in the future. In this handbook, we aim to achieve these elements by covering the breadth of GI, pancreatic, hepatobiliary, and nutritional physiology. Moreover, we include relevant scenario-based clinical case in each chapter so as to evaluate whether the students can apply the basic GI they learn to the clinical setting.
Author : Leonard R. Johnson
Publisher :
ISBN 13 :
Total Pages : 970 pages
Book Rating : 4.3/5 (555 download)
Download or read book Physiology of the Gastrointestinal Tract written by Leonard R. Johnson and published by . This book was released on 1987 with total page 970 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : K. Sejrsen
Publisher : BRILL
ISBN 13 : 9086865666
Total Pages : 600 pages
Book Rating : 4.0/5 (868 download)
Download or read book Ruminant physiology written by K. Sejrsen and published by BRILL. This book was released on 2023-08-28 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains key contributions to the Xth International Symposium on Ruminant Physiology. Proceedings from past ISRP symposia have had a major influence on research and teaching in animal science over the years. Without a doubt the peer-reviewed chapters in this book, written by some of the best scientists in the field, will live up to this fine tradition. The chapters cover a wide range of topics spanning from digestion and absorption to metabolism, reproduction and lactation. Advancement of knowledge within important issues related to rumen fermentation, absorption mechanisms and splanchnic metabolism is treated in nine chapters. A number of chapters address the relationship between nutrition and gene expression illustrating important progress in scientific knowledge that can be obtained by applying the molecular biology methods to the field. Several chapters address the effects of nutrition on immunology and cover topics related to the health and welfare of production animals. In keeping with the increased attention on the relationship between food and human health, the book contains two important chapters on this topic.
Author : Stanley G. Schultz
Publisher : Oxford University Press, USA
ISBN 13 : 9780195208177
Total Pages : 682 pages
Book Rating : 4.2/5 (81 download)
Download or read book Intestinal Absorption and Secretion written by Stanley G. Schultz and published by Oxford University Press, USA. This book was released on 1991 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a thorough, up-to-date survey of the physiological processes through which salt, water, and nutrients are absorbed or secreted by the intestinal tract, and of how these myriad processes are regulated. In twenty-five chapters, written by a team of leading experts, the volume addresses four main topics: the methodologies and basic principles of structure and function; intestinal ion transport; nutrient absorption; and macromolecular transport. Throughout, the contributors emphasize recent developments in the field--for example, neuroendocrine-immune cell interactions in the intestinal mucosa, the regulation of intestinal sodium transport, the cloning of the intestinal glucose carrier, the intestinal cytoskeleton, and the regulation of intestinal epithelial transport function by protein kinases and calmodulin. This is not only the fourth and final volume in the series; it is also the broadest, most contemporary approach to this important topic. As such, this book will be warmly welcomed--and often consulted--by student, scholars, professionals, and anyone researching intestinal absorptive mechanisms and their regulation.
Author : Douglas H. K. Lee
Publisher : Elsevier
ISBN 13 : 1483270041
Total Pages : 256 pages
Book Rating : 4.4/5 (832 download)
Download or read book Physiology, Environment, and Man written by Douglas H. K. Lee and published by Elsevier. This book was released on 2013-09-11 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physiology, Environment, and Man is based on a symposium conducted by the National Academy of Sciences-National Research Council, August 1966. While one might expect a textbook to present its field in organized and comprehensive fashion, a symposium necessarily follows more of an illustrative pattern, according to the personal interests or even idiosyncrasies of the participants. It is interesting to note that, in spite of these limitations, the presentations did in fact cover the range of physiological concerns with environmental effects, from the genetic to the temporal, and from the molecular to the holistic. The book opens with a discussion of the National Academy of Sciences-National Research Council’s broad-based critical study of the physiological underpinning of current concepts of biological responses to toxic chemicals and physical stresses. Subsequent chapters deal with topics such as the metabolic fate of common environmental agents; growth and trophic factors in carcinogenesis; environmental factors in aging and mortality; adaptation to heat and cold; and the definition of an optimum environment.
Author : Thomas E. Andreoli
Publisher : Springer Science & Business Media
ISBN 13 : 1461311438
Total Pages : 687 pages
Book Rating : 4.4/5 (613 download)
Download or read book Molecular Biology of Membrane Transport Disorders written by Thomas E. Andreoli and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: When the six of us gathered to start planning for what was to be the Third Edition of Physiology of Membrane Disorders, it was clear that since 1986, when the Second Edition appeared, the field had experienced the dawning of a new era dominated by a change in focus from phenomenology to underlying mechanisms propelled by the power of molecular biology. In 1985, detailed molecular information was available for only three membrane transporters: the lac permease, bacterial rhodopsin, and the acetylcholine receptor. During the decade that has since elapsed, almost all of the major ion channels and transport proteins have been cloned, sequenced, mutagenized, and expressed in homologous as well as heterologous cells. Few, if any, of the transporters that were identified during the previous era have escaped the probings of the new molecular technologies and, in many instances, considerable insight has been gained into their mechanisms of function in health and disease. Indeed, in some instances novel, unexpected transporters have emerged that have yet to have their functions identified. The decision to adopt the new title Molecular Biology of Membrane Transport Disorders was a natural outgrowth of these considerations.
Author : Jiri Mestecky
Publisher : Elsevier
ISBN 13 : 0080454267
Total Pages : 1995 pages
Book Rating : 4.0/5 (84 download)
Download or read book Mucosal Immunology written by Jiri Mestecky and published by Elsevier. This book was released on 2005-02-02 with total page 1995 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mucosal immunology is so important since most infectious agents enter the body through the various mucous membranes, and many common infections take place in or on mucous membranes. Mucosal Immunology, now in its third edition, is the only comprehensive reference covering the basic science and clinical manifestations of mucosal immunology. This book contains new research data, exceptional illustrations, original theory, a new perspective and excellent organization. The most comprehensive text on mucosal immunology from internationally recognized experts in the field Includes exceptional color illustrations, new research data, original theory and information on all mucosal diseases Contains nine new chapters and an expanded appendix
Author :
Publisher :
ISBN 13 :
Total Pages : 702 pages
Book Rating : 4.M/5 ( download)
Download or read book Gastroenterology Abstracts and Citations written by and published by . This book was released on 1978 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 436 pages
Book Rating : 4.F/5 ( download)
Download or read book Dissertation Abstracts International written by and published by . This book was released on 1983 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
