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Ultrafiltration For Bioprocessing
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Book Synopsis Ultrafiltration for Bioprocessing by : Herb Lutz
Download or read book Ultrafiltration for Bioprocessing written by Herb Lutz and published by Elsevier. This book was released on 2015-02-17 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrafiltration for Bioprocessing is key reading for all those involved in the biotechnology and biopharmaceutical areas. Written by a leading worker in the area, it includes many practical applications and case studies in the key process of ultrafiltration (UF), which is used in almost every bioprocess. - Focuses on ultrafiltration for biopharmaceuticals—other books look at general ultrafiltration or general biopharmaceuticals - A mix of theory and practical applications—other books tend to be more theory-oriented - Addresses the main issues encountered in development and scale-up through recommendations and case studies
Book Synopsis Separation and Purification Technologies in Biorefineries by : Shri Ramaswamy
Download or read book Separation and Purification Technologies in Biorefineries written by Shri Ramaswamy and published by John Wiley & Sons. This book was released on 2013-02-04 with total page 730 pages. Available in PDF, EPUB and Kindle. Book excerpt: Separation and purification processes play a critical role in biorefineries and their optimal selection, design and operation to maximise product yields and improve overall process efficiency. Separations and purifications are necessary for upstream processes as well as in maximising and improving product recovery in downstream processes. These processes account for a significant fraction of the total capital and operating costs and also are highly energy intensive. Consequently, a better understanding of separation and purification processes, current and possible alternative and novel advanced methods is essential for achieving the overall techno-economic feasibility and commercial success of sustainable biorefineries. This book presents a comprehensive overview focused specifically on the present state, future challenges and opportunities for separation and purification methods and technologies in biorefineries. Topics covered include: Equilibrium Separations: Distillation, liquid-liquid extraction and supercritical fluid extraction. Affinity-Based Separations: Adsorption, ion exchange, and simulated moving bed technologies. Membrane Based Separations: Microfiltration, ultrafiltration and diafiltration, nanofiltration, membrane pervaporation, and membrane distillation. Solid-liquid Separations: Conventional filtration and solid-liquid extraction. Hybrid/Integrated Reaction-Separation Systems: Membrane bioreactors, extractive fermentation, reactive distillation and reactive absorption. For each of these processes, the fundamental principles and design aspects are presented, followed by a detailed discussion and specific examples of applications in biorefineries. Each chapter also considers the market needs, industrial challenges, future opportunities, and economic importance of the separation and purification methods. The book concludes with a series of detailed case studies including cellulosic bioethanol production, extraction of algae oil from microalgae, and production of biopolymers. Separation and Purification Technologies in Biorefineries is an essential resource for scientists and engineers, as well as researchers and academics working in the broader conventional and emerging bio-based products industry, including biomaterials, biochemicals, biofuels and bioenergy.
Book Synopsis Basic Biotechniques for Bioprocess and Bioentrepreneurship by : Arvind Kumar Bhatt
Download or read book Basic Biotechniques for Bioprocess and Bioentrepreneurship written by Arvind Kumar Bhatt and published by Academic Press. This book was released on 2023-02-03 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Biotechniques for Bioprocess and Bioentrepreneurship deals with the entire field of industrial biotechnology, starting from the basic laboratory techniques to scale-up, process development, demonstration, and finally its commercialization. The book compiles currently scattered materials on this topic and updates this information based on practical experience and requirements. The book will be an ideal source for new entrepreneurs who wish to start their own commercial units. - Offers guidance for readers/researchers/start-ups/entrepreneurs on how to develop new microbiological and biotechnical processes - Focuses on basic knowledge and possible solutions to the practical difficulties at all levels in one place through understanding of basic techniques in lab, during bioprocess development, commercialization, technology transfer, marketing, and others which is presently not available in the field - Provides multifaceted coverage, with industry insights from experienced practitioners and leaders in the field - Gives possible best solutions to the practical difficulties at all levels, i.e. lab, scaleup, and commercial stage - Addresses ethical and other regulatory issues
Book Synopsis Process Scale Bioseparations for the Biopharmaceutical Industry by : Abhinav A. Shukla
Download or read book Process Scale Bioseparations for the Biopharmaceutical Industry written by Abhinav A. Shukla and published by CRC Press. This book was released on 2006-07-07 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biopharmaceutical industry has become an increasingly important player in the global economy, and the success of these products depends on the development and implementation of cost-effective, robust and scaleable production processes. Bioseparations-also called downstream processing- can be a key source of competitive advantageto biopharmaceut
Book Synopsis Process Validation in Manufacturing of Biopharmaceuticals, Third Edition by : Anurag S. Rathore
Download or read book Process Validation in Manufacturing of Biopharmaceuticals, Third Edition written by Anurag S. Rathore and published by CRC Press. This book was released on 2012-05-09 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: Process Validation in Manufacturing of Biopharmaceuticals, Third Edition delves into the key aspects and current practices of process validation. It includes discussion on the final version of the FDA 2011 Guidance for Industry on Process Validation Principles and Practices, commonly referred to as the Process Validation Guidance or PVG, issued in final form on January 24, 2011. The book also provides guidelines and current practices, as well as industrial case studies illustrating the different approaches that can be taken for successful validation of biopharmaceutical processes. Case studies include Process validation for membrane chromatography Leveraging multivariate analysis tools to qualify scale-down models A matrix approach for process validation of a multivalent bacterial vaccine Purification validation for a therapeutic monoclonal antibody expressed and secreted by Chinese Hamster Ovary (CHO) cells Viral clearance validation studies for a product produced in a human cell line A much-needed resource, this book presents process characterization techniques for scaling down unit operations in biopharmaceutical manufacturing, including chromatography, chemical modification reactions, ultrafiltration, and microfiltration. It also provides practical methods to test raw materials and in-process samples. Stressing the importance of taking a risk-based approach towards computerized system compliance, this book will help you and your team ascertain process validation is carried out and exceeds expectations.
Book Synopsis Continuous Biomanufacturing by : Ganapathy Subramanian
Download or read book Continuous Biomanufacturing written by Ganapathy Subramanian and published by John Wiley & Sons. This book was released on 2017-12-26 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the most comprehensive treatise of this topic available, providing invaluable information on the technological and economic benefits to be gained from implementing continuous processes in the biopharmaceutical industry. Top experts from industry and academia cover the latest technical developments in the field, describing the use of single-use technologies alongside perfusion production platforms and downstream operations. Special emphasis is given to process control and monitoring, including such topics as 'quality by design' and automation. The book is supplemented by case studies that highlight the enormous potential of continuous manufacturing for biopharmaceutical production facilities.
Book Synopsis Microfiltration and Ultrafiltration by : Zeman
Download or read book Microfiltration and Ultrafiltration written by Zeman and published by Routledge. This book was released on 2017-11-22 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrates knowledge on microfiltration and ultrification, membrane chemistry, and characterization methods with the engineering and economic aspects of device performance, device and module design, processes, and applications. The text provides a discussion of membrane fundamentals and an analytical framework for designing and developing new filtrations systems for a broad range of technologically important functions. It offers information on membrane liquid precursors, fractal and stochastic pore space analysis, novel and advanced module designs, and original process design calculations.
Book Synopsis Bioprocess Engineering Principles by : Pauline M. Doran
Download or read book Bioprocess Engineering Principles written by Pauline M. Doran and published by Academic Press. This book was released on 2013 with total page 929 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture, and environmental management. This textbook presents the principles of bioprocess engineering in a way that is accessible to biological scientists.
Book Synopsis Bioprocess Engineering by : Pau Loke Show
Download or read book Bioprocess Engineering written by Pau Loke Show and published by CRC Press. This book was released on 2019-06-13 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioprocess Engineering: Downstream Processing is the first book to present the principles of bioprocess engineering, focusing on downstream bioprocessing. It aims to provide the latest bioprocess technology and explain process analysis from an engineering point of view, using worked examples related to biological systems. This book introduces the commonly used technologies for downstream processing of biobased products. The covered topics include centrifugation, filtration, membrane separation, reverse osmosis, chromatography, biosorption, liquid-liquid separation, and drying. The basic principles and mechanism of separation are covered in each of the topics, wherein the engineering concept and design are emphasized. This book is aimed at bioprocess engineers and professionals who wish to perform downstream processing for their feedstock, as well as students.
Download or read book Membrane Technology written by Z F Cui and published by Elsevier. This book was released on 2010-09-23 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Membrane technology is a rapidly developing area, with key growth accross the process sector, including biotech separation and biomedical applications (e.g. haemodialysis, artificial lungs), through to large scale industrial applications in the water and waste-water processing and the food and drink industries. As processes mature, and the cost of membranes continues to dramatically reduce, so their applications and use are set to expand. Process engineers need access to the latest information in this area to assist with their daily work and to help to develop and apply new and ever more efficient liquid processing solutions. This book covers the latest technologies and applications, with contributions from leading figures in the field. Throughout, the emphasis is on delivering solutions to practitioners. Real world case studies and data from leading organizations -- including Cargill, Lilly, Microbach, ITT -- mean this book delivers the latest solutions as well as a critical working reference to filtration and separation professionals. - Covers the latest technologies and applications in this fast moving bioprocessing sector - Presents a wide range of case studies that ensure readers benefit from the hard-won experience of others, saving time, money and effort - World class author team headed up by the Chair of Chemical Engineering at Oxford University, UK and the VP of Plant Operations and Process Technology at Cargill Corp, the food services company and largest privately owned company in the US
Book Synopsis Marine Bioprocess Engineering by : J.G. Burgess
Download or read book Marine Bioprocess Engineering written by J.G. Burgess and published by Elsevier. This book was released on 1999-11-19 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains full papers of both oral and poster presentations of the international symposium 'Marine Bioprocess Engineering' which was held in Noordwijkerhout, The Netherlands, 1998. The symposium focused on the bioprocessing of marine natural products.Bioprocess engineering has been the key to success in the commercialization of biotechnology, especially with respect to biopharmaceuticals. In marine biotechnology, both new and existing biotechnological techniques are developed an applied to organisms from marine sources. For marine biotechnology, bioprocess engineering represents the link between discovery and commercialization.The diversity of marine life points to a myriad of new bioproducts waiting to be discovered and developed commercially.The volume begins to bridge the gap between the isolation of products from marine organisms in the laboratory and industrial applications by focusing on the bioprocess-engineering aspects. Reviews and recent developments in product discovery, bio-energy production, cultivation of marine organisms, scale up and product recovery are presented.This publication should ensure that the engineering aspects of marine biotechnology will receive further attention in the future. Exploration of new bioproducts from the ocean should be followed up by a sustainable exploitation of these valuable resources.
Book Synopsis Putting Biotechnology to Work by : National Research Council
Download or read book Putting Biotechnology to Work written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability of the United States to sustain a dominant global position in biotechnology lies in maintaining its primacy in basic life-science research and developing a strong resource base for bioprocess engineering and bioproduct manufacturing. This book examines the status of bioprocessing and biotechnology in the United States; current bioprocess technology, products, and opportunities; and challenges of the future and what must be done to meet those challenges. It gives recommendations for action to provide suitable incentives to establish a national program in bioprocess-engineering research, development, education, and technology transfer.
Download or read book Virus filtration written by Kurt Brorson and published by . This book was released on 2008 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Principles Of Bioseparations Engineering by : Raja Ghosh
Download or read book Principles Of Bioseparations Engineering written by Raja Ghosh and published by World Scientific Publishing Company. This book was released on 2006-10-23 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioseparations engineering deals with the scientific and engineering principles involved in large-scale separation and purification of biological products. It is a key component of most chemical engineering/biotechnology/bioprocess engineering programmes. This book discusses the underlying principles of bioseparations engineering written from the perspective of an undergraduate course. It covers membrane based bioseparations in much more detail than some of the other books on bioseparations engineering. Based largely on the lecture notes the author developed to teach the course, this book is especially suitable for use as an undergraduate level textbook, as most other textbooks are targeted at graduate students.
Book Synopsis Validation of Pharmaceutical Processes by : James P. Agalloco
Download or read book Validation of Pharmaceutical Processes written by James P. Agalloco and published by CRC Press. This book was released on 2007-09-25 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised and updated to reflect the significant advances in pharmaceutical production and regulatory expectations, this third edition of Validation of Pharmaceutical Processes examines and blueprints every step of the validation process needed to remain compliant and competitive. The many chapters added to the prior compilation examine va
Download or read book Membrane Filtration written by Greg Foley and published by Cambridge University Press. This book was released on 2013-07-04 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on the application of membranes in an engineering context, this hands-on computational guide makes previously challenging problems routine. It formulates problems as systems of equations solved with MATLAB, encouraging active learning through worked examples and end-of-chapter problems. The detailed treatments of dead-end filtration include novel approaches to constant rate filtration and filtration with a centrifugal pump. The discussion of crossflow microfiltration includes the use of kinetic and force balance models. Comprehensive coverage of ultrafiltration and diafiltration processes employs both limiting flux and osmotic pressure models. The effect of fluid viscosity on the mass transfer coefficient is explored in detail, the effects of incomplete rejection on the design and analysis of ultrafiltration and diafiltration are analysed, and quantitative treatments of reverse osmosis and nanofiltration process analysis and design are explored. Includes a chapter dedicated to the modelling of membrane fouling.
Book Synopsis Bioprocess Engineering by : Bjorn K. Lydersen
Download or read book Bioprocess Engineering written by Bjorn K. Lydersen and published by John Wiley & Sons. This book was released on 1994-04-18 with total page 837 pages. Available in PDF, EPUB and Kindle. Book excerpt: Divided into four sections, the first and third reflect the fact that there are two types of equipment required in the plant--one in which the actual product is synthesized or processed such as the fermentor, centrifuge and chromatographic columns; and the other that supplies support for the facility or process including air conditioning, water and waste systems. Part two describes such components as pumps, filters and valves not limited to a certain type of equipment. Lastly, it covers planning and designing the entire facility along with requirements for containment and validation of the process.
