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Tumor Budding In Colorectal Cancer
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Book Synopsis Tumor Budding in Colorectal Cancer by : Tadahiko Masaki
Download or read book Tumor Budding in Colorectal Cancer written by Tadahiko Masaki and published by Nova Publishers. This book was released on 2006 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumour "budding", which is focused on in this book, is generally defined as an isolated single cancer cell or a cluster composed of a very small number of undifferentiated cancer cells in the stroma of the actively invasive front. The correlation of tumour budding with clinical outcome in colorectal cancer was first reported in the 1980s by Japanese surgeons. Since then, the clinical usefulness of this finding in colorectal cancer has been recognised in many countries. Its usefulness has been clarified not only as a prognostic factor and a potential parameter for a grading system, but also as an indicator for therapeutic decision making. Recently, more objective evaluation of tumour budding has been advocated, and the underlying mechanisms of tumour budding formation have been investigated at the molecular level. In this book, tumour budding in colorectal cancer is discussed from various perspectives. This book provides useful information for all investigators trying to deepen their understanding of colorectal cancer and develop evidence-based therapeutic strategies.
Book Synopsis Surgical Management of Advanced Pelvic Cancer by : Desmond C. Winter
Download or read book Surgical Management of Advanced Pelvic Cancer written by Desmond C. Winter and published by John Wiley & Sons. This book was released on 2021-11-01 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: An innovative guide to the practice of pelvic exenterative surgery for the management of advanced pelvic neoplasms Exenterative surgery plays an important role in the management of advanced pelvic cancer. However, while a large body of evidence regarding outcomes following pelvic exenteration now exists, practical strategies and management options remain unclear. Surgical Management of Advanced Pelvic Cancer addresses this problem by assembling world-leaders in the field to provide insights into the latest techniques and best practices. It includes detailed coverage of: Surgical anatomy Operative approaches and exenterative techniques Reconstruction options Current evidence on survival and quality of life outcomes Featuring essential information for those managing patients with advanced pelvic neoplasms, Surgical Management of Advanced Pelvic Cancer consolidates the latest data and practical advice in one indispensable guide.
Book Synopsis Metastasis of Colorectal Cancer by : Nicole Beauchemin
Download or read book Metastasis of Colorectal Cancer written by Nicole Beauchemin and published by Springer. This book was released on 2012-10-13 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer is the third most common cancer worldwide, and in many parts of the western world, it is the second leading cause of cancer-related deaths. This book covers colon cancer metastasis from the most fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, cell adhesion, natures of liver metastasis, angiogenesis and lymphangiogenesis, inflammatory response, prognostic markers, sentinel node and staging, and finally diagnosis and treatment. Each chapter has been contributed by leaders in the field. A key feature is that it connects with a large readership including students, fundamentalists and clinicians. Another specific feature of the book is that the chapters are written in a didactic and illustrative fashion. These characteristics coupled with the choice of the topics and authors, makes this book a reference in the field. It represents an essential acquisition for medical libraries, clinicians as well as medical and graduate students.
Book Synopsis Deep Learning in Medical Image Analysis by : Gobert Lee
Download or read book Deep Learning in Medical Image Analysis written by Gobert Lee and published by Springer Nature. This book was released on 2020-02-06 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents cutting-edge research and applications of deep learning in a broad range of medical imaging scenarios, such as computer-aided diagnosis, image segmentation, tissue recognition and classification, and other areas of medical and healthcare problems. Each of its chapters covers a topic in depth, ranging from medical image synthesis and techniques for muskuloskeletal analysis to diagnostic tools for breast lesions on digital mammograms and glaucoma on retinal fundus images. It also provides an overview of deep learning in medical image analysis and highlights issues and challenges encountered by researchers and clinicians, surveying and discussing practical approaches in general and in the context of specific problems. Academics, clinical and industry researchers, as well as young researchers and graduate students in medical imaging, computer-aided-diagnosis, biomedical engineering and computer vision will find this book a great reference and very useful learning resource.
Book Synopsis Digital Pathology by : Constantino Carlos Reyes-Aldasoro
Download or read book Digital Pathology written by Constantino Carlos Reyes-Aldasoro and published by Springer. This book was released on 2019-07-03 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 15th European Congress on Digital Pathology, ECDP 2019, held in Warwick, UK in April 2019. The 21 full papers presented in this volume were carefully reviewed and selected from 30 submissions. The congress theme will be Accelerating Clinical Deployment, with a focus on computational pathology and leveraging the power of big data and artificial intelligence to bridge the gaps between research, development, and clinical uptake.
Book Synopsis Colorectal Cancer by : Valeria Barresi
Download or read book Colorectal Cancer written by Valeria Barresi and published by . This book was released on 2022 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer is one of the most common malignancies worldwide, and the pathogenesis of this neoplasm is probably one of the most studied. The knowledge obtained over time has led to the development of screening and early diagnosis systems, allowing a significant reduction in the incidence of this neoplasm. However, what is currently known probably represents only the tip of the iceberg of the biology of this tumor. It was recently shown that the gut microbiota may contribute to colorectal cancerogenesis. In addition, several novel targeted therapies are now applied to patients with colorectal carcinoma. Nonetheless, several questions are still unanswered. Could the modulation of the gut microbiota modify the risk of tumor progression or the efficacy of therapies? Are there any predictive biomarkers of the risk of tumor progression or the efficacy of target therapies? Is metastatic colorectal cancer one or more diseases? This book collects a series of scientific articles reflecting part of the state of the art regarding colorectal cancer, seeking to answer these questions.
Download or read book Tumor Deposits written by Sulen Sarioglu and published by Springer. This book was released on 2018-01-09 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the morphology, possible mechanisms of formation, and clinical relevance of tumor deposits (TDs) in different organs and parts of the body. It also describes the diagnostic features that are currently available for TDs and discusses the prognostic impact of TDs. The poor prognostic and predictive values of TDs were found to be as strong as distant metastasis in different series. TDs, best characterized by colorectal cancer, are irregular discrete tumor masses that are discontinuous from the leading edge of the tumor. However, even in colorectal cancers, the place of TDs in tumor staging (tumor, lymph node and distant metastasis categories) remains controversial. This book presents the possible mechanisms of TD formation, including neurotrophic and angiotrophic extravascular migratory metastasis, in comparison with the well-known mechanisms of metastasis. It also shows that TDs were identified in esophageal, gastric, salivary gland, head and neck, and breast carcinomas. The possible mechanisms leading to the frequent association of TDs and peritoneal carcinomatosis are discussed. This is a valuable resource for pathologists, oncologists, and surgeons who are looking for detailed information on the latest scientific insights into the pathology and prognostic implications of TDs.
Book Synopsis Prognostic Factors in Cancer by : Paul Hermanek
Download or read book Prognostic Factors in Cancer written by Paul Hermanek and published by Springer Verlag. This book was released on 1995 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Tumor Stroma written by Jai Prakash and published by CRC Press. This book was released on 2022-01-27 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The identification of the role of tumor stroma—the tissue in the surroundings of cancer cells—in cancer development, progression, and metastasis has revolutionized the fields of cancer biology as well as cancer therapeutics. This book provides a comprehensive overview of this rapidly-evolving field including tumor stroma biology, therapeutic targets, molecular imaging, and advanced tumor stroma in vitro models. The book will serve as a handbook for graduate students, postgraduate researchers, pharmaceutical scientists, and biomedical engineers.
Book Synopsis Tumor Vascularization by : Domenico Ribatti
Download or read book Tumor Vascularization written by Domenico Ribatti and published by Academic Press. This book was released on 2020-01-07 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a valuable source for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in tumor progression and blood vessels.
Book Synopsis Endoscopic Management of Colorectal T1(SM) Carcinoma by : Shinji Tanaka
Download or read book Endoscopic Management of Colorectal T1(SM) Carcinoma written by Shinji Tanaka and published by Springer. This book was released on 2019-07-26 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the latest information on diagnosis and treatment strategies for colorectal T1(SM) carcinoma including endoscopic resection, and pathologic diagnosis and treatment following resection. Due to constant advances, the curative phase after the endoscopic resection of carcinomas has extended, shifting the endpoints of diagnosis and treatment strategies. This book thoroughly summarizes the latest findings, explained with the help of abundant color figures, and will serve as a basis for further discussions and advances in this field. Endoscopic Management of Colorectal T1(SM) Carcinoma offers a valuable resource for colonoscopists, colorectal surgeons, and pathologists at all levels. The readers will discover diverse perspectives, provided by the contributing authors, and extensive discussions that are analyzed from Asian perspectives, which often differ from those found in Western texts.
Book Synopsis Lymphatic Metastasis and Sentinel Lymphonodectomy by : Peter Schlag
Download or read book Lymphatic Metastasis and Sentinel Lymphonodectomy written by Peter Schlag and published by Springer Science & Business Media. This book was released on 2000 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume gives a general summary of the current understanding of lymphatic metastasis and the possibilities of more specific detection of lymph node metastasis. It describes in detail the procedure of sentinel lymph node detection in urogenital tumors, neck and thyroid tumors, malignant melanoma, gastric and colorectal cancer and tumors of the breast. The potential and limitations of this new method are discussed. This book provides comprehensive insight into a both clinically and scientifically important new field which is bringing about a marked improvement in the treatment of malignant tumors.
Book Synopsis TNM Staging Atlas with Oncoanatomy by : Philip Rubin
Download or read book TNM Staging Atlas with Oncoanatomy written by Philip Rubin and published by Lippincott Williams & Wilkins. This book was released on 2013-01-30 with total page 1486 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Second Edition of TNM Staging Atlas with Oncoanatomy has been updated to include all new cancer staging information from the Seventh Edition of the AJCC Cancer Staging Manual. The atlas presents cancer staging in a highly visual rapid-reference format, with clear full-color diagrams and TNM stages by organ site. The illustrations are three-dimensional, three-planar cross-sectional presentations of primary anatomy and regional nodal anatomy. They show the anatomic features identifiable on physical and/or radiologic examination and the anatomic extent of cancer spread which is the basis for staging. A color code indicates the spectrum of cancer progression at primary sites (T) and lymph node regions (N). The text then rapidly reviews metastatic spread patterns and their incidence. For this edition, CT or MRI images have been added to all site-specific chapters to further detail cancer spread and help plan treatment. Staging charts have been updated to reflect changes in AJCC guidelines, and survival curves from AJCC have been added.
Book Synopsis MicroRNAs in Cancer by : Cesar Lopez-Camarillo
Download or read book MicroRNAs in Cancer written by Cesar Lopez-Camarillo and published by CRC Press. This book was released on 2013-02-22 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: MicroRNA (miRNA) biology is a cutting-edge topic in basic as well as biomedical research. This is a specialized book focusing on the current understanding of the role of miRNAs in the development, progression, invasion, and metastasis of diverse types of cancer. It also reviews their potential for applications in cancer diagnosis, prognosis, and th
Book Synopsis Modern Immunohistochemistry by : Peiguo Chu
Download or read book Modern Immunohistochemistry written by Peiguo Chu and published by Cambridge University Press. This book was released on 2014-02-27 with total page 1179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the publication of the first edition of this best-selling book in 2009, the field of immunohistochemistry has advanced significantly. Fully updated to reflect the latest developments in the field, Modern Immunohistochemistry, Second Edition, is a practical guide to all the important diagnostic markers in each organ system. Concise text is supplemented by over 1,100 high-quality colour images and algorithms. The new edition features even more summary tables, highlighting the key points of differential immunophenotypic panels. A new, expanded introduction explains the basic principles of immunohistochemistry, and chapters have been updated to incorporate predictive/prognostic markers and the latest WHO classifications. All chapters are written by the same expert authors, providing a consistent, engaging style throughout and avoiding contradictory advice. An essential text for residents, this is also an extremely valuable resource for practitioners in anatomic pathology wishing to familiarise themselves with diagnostic markers at a quick glance.
Book Synopsis Colorectal Cancer Biology by : Rajunor Ettarh
Download or read book Colorectal Cancer Biology written by Rajunor Ettarh and published by IntechOpen. This book was released on 2012-02-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer is a common disease, affecting millions worldwide and represents a global health problem. Effective therapeutic solutions and control measures for the disease will come from the collective research efforts of clinicians and scientists worldwide. This book presents the current status of the strides being made to understand the fundamental scientific basis of colorectal cancer. It provides contributions from scientists, clinicians and investigators from 20 different countries. The four sections of this volume examine the evidence and data in relation to genes and various polymorphisms, tumor microenvironment and infections associated with colorectal cancer. An increasingly better appreciation of the complex inter-connected basic biology of colorectal cancer will translate into effective measures for management and treatment of the disease. Research scientists and investigators as well as clinicians searching for a good understanding of the disease will find this book useful.
Book Synopsis Physics of Cancer by : Claudia Mierke
Download or read book Physics of Cancer written by Claudia Mierke and published by Iph001. This book was released on 2018-10-24 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.