Translational Neurosonology

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Translational Neurosonology

Author : A. Alonso
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 331802791X
Total Pages : 130 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Translational Neurosonology by : A. Alonso

Download or read book Translational Neurosonology written by A. Alonso and published by Karger Medical and Scientific Publishers. This book was released on 2014-12-16 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic ultrasound has become an elementary tool for evaluating cerebrovascular diseases and plays a prominent role in routine clinical practice. Many publications attempt to cover the continuous progress of its diagnostic and even therapeutic applications. However, the impact ultrasound has made in recent years in the fields of animal studies and human research is less well known. This publication provides an overview on exciting current attempts in neurological diseases, ranging from experimental approaches to established imaging modes ready to be incorporated into the routine of daily practice. The first part of the book concentrates on basic principles of neurosonology and focuses on contrast imaging, specific ultrasound contrast agents and safety aspects. The following chapters deal with different vascular ultrasound applications, allowing an optimized characterization of atherosclerotic disease and monitoring of cerebral autoregulation. In addition, the role of parenchymal ultrasound imaging in cerebrovascular diseases and movement disorders is illustrated. The final chapters look at promising new therapeutic approaches implementing ultrasound although they are still no more than experimental. The book can be highly recommended to clinical neurologists with good knowledge in clinical ultrasound who wish to gain a compact and updated insight into the plethora of capabilities of neurosonology in the future.

Translational Neuroscience

Author : Edgar Garcia-Rill
Publisher : John Wiley & Sons
ISBN 13 : 047096071X
Total Pages : 176 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Translational Neuroscience by : Edgar Garcia-Rill

Download or read book Translational Neuroscience written by Edgar Garcia-Rill and published by John Wiley & Sons. This book was released on 2012-02-07 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational research looks to take the latest innovations made in the laboratory setting to translate findings into effective and sustainable medical interventions and improved preventative measures. Funding support is increasingly tied to practical healthcare outcomes, with this trend likely only to increase in coming years, Translational Neuroscience: A Guide to a Successful Program, is a timely guide to developing research programs that bring translational advances to the forefront. Translational Neuroscience provides practical information from scientists with first-hand experience in developing a cutting-edge translational facility. The book opens with chapters that provide guidance to organizing a center for translational science. Chapters look at topics ranging from mentoring and career planning for clinician scientists to improving the design of core facilities and addressing infrastructure needs. The second half of the book provides valuable case studies of translational neuroscience in action, with examples ranging from using to transcranial magnetic stimulation to studies on drug abuse and telemedicine applications. The final chapter looks to the future of basic science research, how academic health centers can be reorganized, and how future generations of translational neuroscientists can be trained. Translational Neuroscience provides a blueprint to developing an innovative and successful translational research program. Deans, department chairs, academic health center administrators, and researchers will find this guide useful for drafting programs in translational research and avoiding costly pitfalls. While grounded in examples from basic neuroscience research, this book will be a useful tool to all scientists looking to develop centers of translational science across research disciplines.

Conn's Translational Neuroscience

Author : P. Michael Conn
Publisher : Academic Press
ISBN 13 : 0128025964
Total Pages : 778 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Conn's Translational Neuroscience by : P. Michael Conn

Download or read book Conn's Translational Neuroscience written by P. Michael Conn and published by Academic Press. This book was released on 2016-09-28 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conn’s Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn’s Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance Features contributions from leading global basic and clinical investigators in the field Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes Relates and translates the current science to the understanding of neurological disorders and their treatment

Translational Neuroscience

Author : Mark H. Tuszynski
Publisher : Springer
ISBN 13 : 148997654X
Total Pages : 584 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Translational Neuroscience by : Mark H. Tuszynski

Download or read book Translational Neuroscience written by Mark H. Tuszynski and published by Springer. This book was released on 2016-03-08 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Neuroscience offers a far-reaching and insightful series of perspectives on the effort to bring potentially revolutionary new classes of therapies to the clinic, thereby transforming the treatment of human nervous system disorders. Great advances in the fields of basic neuroscience, molecular biology, genomics, gene therapy, cell therapy, stem cell biology, information technology, neuro devices, rehabilitation and others over the last 20 years have generated unprecedented opportunities to treat heretofore untreatable disorders of the nervous system. This book provides a wide-ranging yet detailed sample of many of these efforts, together with the methods for pursuing clinical translation and assessing clinical outcomes. Among the topics covered are Alzheimer’s disease, Parkinson’s disease, stroke, multiple sclerosis, epilepsy, motor neuron disease, pain, inborn errors of metabolism, brain tumors, spinal cord injury, neuroprosthetics, rehabilitation and clinical trial design/consideration. Translational Neuroscience is aimed at basic neuroscientists, translational neuroscientists and clinicians who seek to gain a perspective on the nature and promise of translational therapies in the current era. Both students and established professionals will benefit from the content.

Translational Neuroscience

Author : Karoly Nikolich
Publisher : MIT Press
ISBN 13 : 0262329867
Total Pages : 319 pages
Book Rating : 4.2/5 (623 download)

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Book Synopsis Translational Neuroscience by : Karoly Nikolich

Download or read book Translational Neuroscience written by Karoly Nikolich and published by MIT Press. This book was released on 2015-08-21 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experts from academia and industry discuss how to create a new, more effective translational neuroscience drawing on novel technology and recent discoveries. Today, translational neuroscience faces significant challenges. Available therapies to treat brain and nervous system disorders are extremely limited and dated, and further development has effectively ceased. Disinvestment by the private sector occurred just as promising new technologies in genomics, stem cell biology, and neuroscience emerged to offer new possibilities. In this volume, experts from both academia and industry discuss how novel technologies and reworked translation concepts can create a more effective translational neuroscience. The contributors consider such topics as using genomics and neuroscience for better diagnostics and biomarker identification; new approaches to disease based on stem cell technology and more careful use of animal models; and greater attention to human biology and what it will take to make new therapies available for clinical use. They conclude with a conceptual roadmap for an effective and credible translational neuroscience—one informed by a disease-focused knowledge base and clinical experience. Contributors Tobias M. Böckers, Thomas Bourgeron, Karl Broich, Nils Brose, Bruce N. Cuthbert, Ilka Diester, Gül Dölen, Guoping Feng, Richard Frackowiak, Raquel E. Gur, Stephan Heckers, Franz Hefti, David M. Holtzman, Steven E. Hyman, Nancy Ip, Cynthia Joyce, Tobias Kaiser, Edward H. Koo, Walter J. Koroshetz, Katja S. Kroker, Robert C. Malenka, Isabelle Mansuy, Eliezer, Masliah, Yuan Mei, Andreas Meyer-Lindenberg, Lennart Mucke, Pierluigi Nicotera, Karoly Nikolich, Michael J. Owen, Menelas N. Pangalos, Alvaro Pascual-Leone, Joel S. Perlmutter, Trevor W. Robbins, Lee L. Rubin, Akira Sawa, Mareike Schnaars, Bernd Sommer, Maria Grazia Spillantini, Laura Spinney, Matthew W. State, Marius Wernig

NEUROTHERAPEUTICS IN THE ERA OF TRANSLATIONAL MEDICINE.

Author : RICHARD A. SMITH
Publisher : Elsevier
ISBN 13 : 0323907261
Total Pages : 518 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis NEUROTHERAPEUTICS IN THE ERA OF TRANSLATIONAL MEDICINE. by : RICHARD A. SMITH

Download or read book NEUROTHERAPEUTICS IN THE ERA OF TRANSLATIONAL MEDICINE. written by RICHARD A. SMITH and published by Elsevier. This book was released on 2021 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Progress in Translational Neuroimaging: Integrating Pathways, Systems and Phenomenology in Neurology and Psychiatry

Author : Drozdstoy Stoyanov
Publisher : Frontiers Media SA
ISBN 13 : 2889639541
Total Pages : 175 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Progress in Translational Neuroimaging: Integrating Pathways, Systems and Phenomenology in Neurology and Psychiatry by : Drozdstoy Stoyanov

Download or read book Progress in Translational Neuroimaging: Integrating Pathways, Systems and Phenomenology in Neurology and Psychiatry written by Drozdstoy Stoyanov and published by Frontiers Media SA. This book was released on 2020-08-21 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Translational Neuroimaging

Author : Robert A. McArthur
Publisher : Academic Press
ISBN 13 : 0123869978
Total Pages : 463 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Translational Neuroimaging by : Robert A. McArthur

Download or read book Translational Neuroimaging written by Robert A. McArthur and published by Academic Press. This book was released on 2012-10-05 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment combines the experience of academic, clinical and industrial neuroimagers in a unique collaborative approach to provide an integrated perspective of the use of small animal and human brain imaging in developing and validating translational models and biomarkers for the study and treatment of neuropsychiatric disorders. Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment examines the translational role of neuroimaging in model development from preclinical animal models, to human experimental medicine, and finally to clinical studies. The focus of this book is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This book covers methodical issues in human and animal neuroimaging translational research as well as detailed applied examples of the use of neuroimaging in neuropsychiatric disorders and the development of drugs for their treatment. Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment appeals to non-clinical and clinical neuroscientists working in and studying neuropsychiatric disorders and their treatment as well as providing the novice researcher or researcher outside of his/her expertise the opportunity to understand the background of translational research and the use of imaging in this field. Provides a background to translational research and the use of brain imaging in neuropsychiatric disorders Critical discussion of the potential and limitations of neuroimaging as a translational tool for identifying and validating biomarkers Identifies cross species neurosystems and common endpoints necessary to help accelerate CNS drug discovery and development for the treatment of neuropsychiatric disorders

Translational Medicine in CNS Drug Development

Author : George G. Nomikos
Publisher : Academic Press
ISBN 13 : 0128031646
Total Pages : 458 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Translational Medicine in CNS Drug Development by : George G. Nomikos

Download or read book Translational Medicine in CNS Drug Development written by George G. Nomikos and published by Academic Press. This book was released on 2019-06-18 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Medicine in CNS Drug Development, Volume 29, is the first book of its kind to offer a comprehensive overview of the latest developments in translational medicine and biomarker techniques. With extensive coverage on all aspects of biomarkers and personalized medicine, and numerous chapters devoted to the best strategies for developing drugs that target specific disorders, this book presents an essential reference for researchers in neuroscience and pharmacology who need the most up-to-date techniques for the successful development of drugs to treat central nervous system disorders. Despite increases in the number of individuals suffering from CNS-related disorders, the development and approval of drugs for their treatment have been hampered by inefficiencies in advancing compounds from preclinical discovery to the clinic. However, in the past decades, game-changing strides have been made in our understanding of the pathophysiology of CNS disorders and the relationship of drug exposure in plasma and CNS to pharmacodynamic measures in both animals and humans. Includes comprehensive coverage of biomarker tools and the role of personalized medicine in CNS drug development Discusses strategies for drug development for a full range of CNS indications, with particular attention to neuropsychiatric and neurocognitive disorders Includes chapters written by international experts from industry and academia

Translational Neuroscience

Author : James Elmer Barrett
Publisher :
ISBN 13 : 9781139514804
Total Pages : 366 pages
Book Rating : 4.5/5 (148 download)

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Book Synopsis Translational Neuroscience by : James Elmer Barrett

Download or read book Translational Neuroscience written by James Elmer Barrett and published by . This book was released on 2012 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive analysis of translational neuroscience, covering all major areas of psychiatry, neurology and neurodevelopmental disorders.

Manual of Neurosonology

Author : László Csiba
Publisher : Cambridge University Press
ISBN 13 : 1316688267
Total Pages : 333 pages
Book Rating : 4.3/5 (166 download)

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Book Synopsis Manual of Neurosonology by : László Csiba

Download or read book Manual of Neurosonology written by László Csiba and published by Cambridge University Press. This book was released on 2016-04-28 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurosonology is non-invasive, portable, and has excellent temporal resolution, making it a valuable and increasingly popular tool for the diagnosis and monitoring of neurological conditions when compared to other imaging techniques. This guide looks beyond the use of neurovascular ultrasound in stroke to encompass a wide range of other neurological diseases and emergencies. It offers a practical approach to the examination of patients, interpretation of ultrasound studies, and the application of neurosonology to the development of management and treatment strategies. Each chapter incorporates a thorough and clear procedural methodology alongside scanning tips for trainees; this step-by-step approach is further enhanced by example images and focused diagnostic questions. Authored and edited by international experts, this practical manual of neurosonology is an invaluable resource for neurologists, neurosurgeons, intensivists, radiologists and ultrasonographers.

Procedural Manual of Neurosonology

Author : Jose C. Navarro
Publisher : Cambridge Scholars Publishing
ISBN 13 : 1527535975
Total Pages : 153 pages
Book Rating : 4.5/5 (275 download)

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Book Synopsis Procedural Manual of Neurosonology by : Jose C. Navarro

Download or read book Procedural Manual of Neurosonology written by Jose C. Navarro and published by Cambridge Scholars Publishing. This book was released on 2019-06-13 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by several stroke neurosonology experts in Asia, this volume brings together the diverse experiences and skills of a number of leading practitioners in the field. In addition to detailing the ‘science’ behind various neurosonological evaluations, it documents the ‘art’ of performing these tests and provides representative cases encountered in neurovascular laboratories and day-to-day clinical practice. This book will serve as a reference point for sonographers and interpreting neurologists, particularly with regards to transcranial Doppler and cervical duplex examinations.

Neurosonology and Neuroimaging of Stroke

Author : Jose M. Valdueza
Publisher : Thieme
ISBN 13 : 1604060794
Total Pages : 401 pages
Book Rating : 4.6/5 (4 download)

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Book Synopsis Neurosonology and Neuroimaging of Stroke by : Jose M. Valdueza

Download or read book Neurosonology and Neuroimaging of Stroke written by Jose M. Valdueza and published by Thieme. This book was released on 2011-01-01 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for this book:An excellent textbook accompanied by high quality illustrations illustrating clinical applications, [and the] advantages and limitations of ultrasound examinations of the central nervous system.--RAD MagazineNeurosonology and Neuroimaging of Stroke is a comprehensive reference for the diagnosis and management of cerebrovascular disease using neurosonology. Divided into two main parts, the book opens with an in-depth overview of the fundamental principles of neurosonology. It describes ultrasound anatomy, examination techniques, the essential technical concepts for clinical applications, as well as the pathogenesis of stroke and vascular pathology. The second part of the book presents 30 cases of various levels of difficulty. For each case, the book provides concise descriptions of clinical presentation, initial neuroradiological findings, suspected diagnosis, the angiological questions, and final diagnosis. Each case concludes with a detailed discussion, enabling the clinician to gain a solid understanding of the diagnosed disease and the angiologic questions arising from the case. Features: Practical discussion of 30 clinical scenarios thoroughly prepares the clinician for the range of frequently encountered problems Consistent presentation aids rapid reference to cases of interest More than 750 high-quality illustrations, including full-color Doppler images Nearly 100 video clips on the accompanying MediaCenter web page demonstrate anatomy, imaging concepts, and select cases included in the book A reference and casebook in a single volume, Neurosonology and Neuroimaging of Strokeis ideal for clinicians seeking to optimize care for patients by enhancing their knowledge of this important diagnostic tool.

Neurosonology and Neuroimaging of Stroke

Author : José Manuel Valdueza
Publisher : Thieme
ISBN 13 : 3132579939
Total Pages : 1777 pages
Book Rating : 4.1/5 (325 download)

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Book Synopsis Neurosonology and Neuroimaging of Stroke by : José Manuel Valdueza

Download or read book Neurosonology and Neuroimaging of Stroke written by José Manuel Valdueza and published by Thieme. This book was released on 2017-01-25 with total page 1777 pages. Available in PDF, EPUB and Kindle. Book excerpt: HIGHLY COMMENDED by the BMA Medical Book Awards for Neurology! Neurosonology and Neuroimaging of Stroke: A Comprehensive Reference Neurosonology is a first-line modality in the diagnosis and management of cerebrovascular disease and especially of stroke. In this new edition of Neurosonology and Neuroimaging of Stroke, this noninvasive, realtime imaging method has been given expanded coverage, particularly for its clinical utility. As in the first edition, the new edition offers both a clear overview of the principles of neurosonology and a casebook exploring critical cerebrovascular problems. Ultrasound anatomy, technical aspects of clinical application, and the advantages and limitations of ultrasound are reviewed and contrasted to conventional, magnetic resonance, and computed tomography angiography. Forty-five selected cases from the authors' extensive collections at Charite - Universitatsmedizin Berlin and the Center of Neurology in Bad Segeberg, Germany, are then discussed. The patient histories and working diagnoses are followed by detailed assessments of the extra- and intracranial color-coded duplex sonographic findings and additional diagnostic procedures. The relevant clinical aspects are presented in a compact, comprehensible way, and for the majority of the cases videos are available in the Thieme MediaCenter, providing further in-depth understanding of the full potential of the method. Features: Complete extra- and intracranial arterial and venous ultrasound examination New techniques: ultrasound fusion imaging, ultrafast ultrasound, contrast application More than 1,300 high-quality illustrations, including full-color duplex images Fifteen newly selected cases on conditions such as subarachnoid hemorrhage and dural fistula, as well as rare stroke causes including sickle cell disease and reversible cerebral vasoconstriction syndrome Revision of many cases from the first edition More than 60 new video clips (for a total of 130) available at the Thieme MediaCenter, bringing ultrasound anatomy and challenging cases to your monitor! Neurosonology and Neuroimaging of Stroke, Second Edition, offers neurologists, neuroradiologists, and all physicians treating patients with cerebrovascular disease an authoritative introduction and guide to this powerful diagnostic tool.

The Right Therapy for Neurological Disorders

Author : E. Beghi
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318058653
Total Pages : 180 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis The Right Therapy for Neurological Disorders by : E. Beghi

Download or read book The Right Therapy for Neurological Disorders written by E. Beghi and published by Karger Medical and Scientific Publishers. This book was released on 2016-07-26 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most neurological disorders are chronic and aging-related. With the increase of life expectancy their incidence and prevalence will grow in the decades to come, which in turn will increase the load on medical and social systems worldwide. There is thus a desperate need for successful preventive and therapeutic measures based on randomized clinical trials (RTCs) conducted by independent organizations. This book provides a compendium relating most of the principles of reliable RTCs to specific neurological diseases. Contributed by specialized neurologists, the articles touch on important aspects of RCTs with a clear critical approach, highlighting their limitations as well as giving recommendations for their planning and conducting to address the variable genotypic and phenotypic aspects of neurological conditions. Consideration is also given to combining the clinical impact of the study results with patients’ values and the interests of pharmaceutical companies. Neurologists involved in clinical trials will certainly benefit from this book, which should become a basic text for all neurological courses dealing with evidence-based neurology.

War Neurology

Author : L. Tatu
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318056065
Total Pages : 253 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis War Neurology by : L. Tatu

Download or read book War Neurology written by L. Tatu and published by Karger Medical and Scientific Publishers. This book was released on 2016-04-04 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in the history of neurological science has increased significantly during the last decade, but the significance of war has been overlooked in related research. In contrast, this book highlights war as a factor of progress in neurological science. Light is shed on this little-known topic through accounts given by neurologists in war, experiences of soldiers suffering from neurological diseases, and chapters dedicated to neurology in total and contemporary war. Written by experts, the contributions in this book focus on the Napoleonic Wars, the American Civil War, the Franco-Prussian War of 1870, World Wars I and II, and recent conflicts such as Vietnam or Afghanistan. Comprehensive yet concise and accessible, this book serves as a fascinating read for neurologists, neurosurgeons, psychiatrists, historians, and anyone else interested in the history of neurology.

New Insights in Intracerebral Hemorrhage

Author : K. Toyoda
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318055972
Total Pages : 208 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis New Insights in Intracerebral Hemorrhage by : K. Toyoda

Download or read book New Insights in Intracerebral Hemorrhage written by K. Toyoda and published by Karger Medical and Scientific Publishers. This book was released on 2015-11-13 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: The age-standardized mortality rate for hemorrhagic stroke has decreased worldwide over the past two decades, but incidence, number of deaths, and lost disability-adjusted life-years (DALY) continue to increase. Moreover, hemorrhagic stroke occurs half as frequently globally as ischemic stroke, but causes significantly more deaths and lost DALY. Milestone studies of the past decade - STICH, FAST, and INTERACT2 - indicate the importance of hyperacute care for intracerebral hemorrhage; despite this, there is to date no established strategy for patients analogous to reperfusion therapy for ischemic stroke. This book, written by world-renowned experts, covers all current topics related to the diagnosis and management of intracerebral hemorrhage. It will contribute to an improved understanding of current and future aspects concerning optimal management of patients. This is a comprehensive, up-to-date resource for neurologists, neurosurgeons and trainees.