Trace Analysis By Ms Ms On A Double Focussing Mass Spectrometer

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Trace Analysis by MS/MS on a Double Focussing Mass Spectrometer

Author : V. T. Borrett
Publisher :
ISBN 13 : 9780642123008
Total Pages : 8 pages
Book Rating : 4.1/5 (23 download)

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Book Synopsis Trace Analysis by MS/MS on a Double Focussing Mass Spectrometer by : V. T. Borrett

Download or read book Trace Analysis by MS/MS on a Double Focussing Mass Spectrometer written by V. T. Borrett and published by . This book was released on 1987 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in mass spectrometry - mass spectrometry (ms/ms) indicate that this techniques has a number of advantages over conventional methods for identification and trace analysis of organic materials (1). The method involves detection of fragment or daughter ions which arise from spontaneous or collisionally activated decomposition of parent ions in a field free region of the spectrometer. The main advantages are the additional information provided in the form of generic relationships between ions in the mass spectrum and the high specificity which can be achieved. In many cases, data obtained by ms/ms is sufficient to differentiate between isomeric structures. Although the ion intensity observed by ms/ms methods is considerably lower than with conventional MS, the reduction in 'chemical noise' is generally sufficient to allow detection of compounds at low levels by direct mixture analysis.

Trace Analysis By Mass Spectrometry

Author : Arthur J. Ahearn
Publisher : Elsevier
ISBN 13 : 0323140734
Total Pages : 475 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Trace Analysis By Mass Spectrometry by : Arthur J. Ahearn

Download or read book Trace Analysis By Mass Spectrometry written by Arthur J. Ahearn and published by Elsevier. This book was released on 2012-12-02 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: Trace Analysis by Mass Spectrometry deals with trace analysis of solids and liquids by mass spectrometric techniques. Topics include the physics and techniques of electrical discharge ion sources, transmission of ions through double focusing mass spectrometers, and detection and measurement of ions by ion-sensitive plates. The ion sources used are principally electrical discharge type sources. This book is comprised of 14 chapters. The first several chapters focus on the basic physics of electrical discharge ion sources, double focusing mass spectrometry, and the measurement of arrays of mass resolved ion beams by electrical detection methods and with ion sensitive emulsions. The discussion then shifts to the problem of obtaining the chemical composition of the recorded mass resolved ion sample and relating this composition to that of the original sample. The chapters that follow describe specific techniques for analyzing special samples such as insulators, powders, microsamples, biological materials, reactive and low melting point substances, radioactive materials, and gases in solids. The remaining chapters include the use of laser ion sources in the analysis of solids and the analysis of surfaces particularly with sputter ion sources. This book will be of interest to students and practitioners of physics and chemistry.

Trace Quantitative Analysis by Mass Spectrometry

Author : Robert K. Boyd
Publisher : John Wiley & Sons
ISBN 13 : 1119964393
Total Pages : 1179 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Trace Quantitative Analysis by Mass Spectrometry by : Robert K. Boyd

Download or read book Trace Quantitative Analysis by Mass Spectrometry written by Robert K. Boyd and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 1179 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a serious introduction to the subject of mass spectrometry, providing the reader with the tools and information to be well prepared to perform such demanding work in a real-life laboratory. This essential tool bridges several subjects and many disciplines including pharmaceutical, environmental and biomedical analysis that are utilizing mass spectrometry: Covers all aspects of the use of mass spectrometry for quantitation purposes Written in textbook style to facilitate understanding of this topic Presents fundamentals and real-world examples in a ‘learning-though-doing’ style

Principles and Applications of Clinical Mass Spectrometry

Author : Nader Rifai
Publisher : Elsevier
ISBN 13 : 0128160640
Total Pages : 218 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Principles and Applications of Clinical Mass Spectrometry by : Nader Rifai

Download or read book Principles and Applications of Clinical Mass Spectrometry written by Nader Rifai and published by Elsevier. This book was released on 2018-06-26 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of mass spectrometers, and sample preparation for analysis; the second half outlines the main applications of this technology within clinical laboratory settings, including determination of small molecules and peptides, as well as pathogen identification. A thorough yet succinct guide to using mass spectrometry technology in the clinical laboratory, Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is an essential resource for chemists, pharmaceutical and biotech researchers, certain government agencies, and standardization groups. Provides concrete examples of the main applications of mass spectrometry technology Describes current capabilities of the LC- and MS-based analytical methods Details methods for successful analytical work in the field

Opportunities to Improve Airport Passenger Screening with Mass Spectrometry

Author : Committee on Assessment of Security Technologies for Transportation
Publisher : National Academies Press
ISBN 13 : 9780309092401
Total Pages : 35 pages
Book Rating : 4.0/5 (924 download)

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Book Synopsis Opportunities to Improve Airport Passenger Screening with Mass Spectrometry by : Committee on Assessment of Security Technologies for Transportation

Download or read book Opportunities to Improve Airport Passenger Screening with Mass Spectrometry written by Committee on Assessment of Security Technologies for Transportation and published by National Academies Press. This book was released on 2004-05-26 with total page 35 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protection of the traveling public from terrorist threats involving explosives is a major goal of the Transportation Security Administration (TSA). For 20 years, the TSA (and the Federal Aviation Administration before it) have been investing in technologies to meet that goal. To support that activity, the TSA has asked the NRC to assess a variety of technological opportunities for offering such protection. The NRC is approaching this assignment by issuing a series of reports on chosen technology applications. This is the first of that series and presents an assessment of mass spectrometry for enhanced trace detection (ETD) of chemicals contained in explosives. The report describes limitations of trace detection in general and the current technologies in particular. It then presents a discussion of the potential for mass spectrometry to improve EDT including challenges faced by such a system, recommendations for starting a program to take advantage of mass spectrometry, and recommendations for a phased implementation plan.

Analyzing Biomolecular Interactions by Mass Spectrometry

Author : Jeroen Kool
Publisher : John Wiley & Sons
ISBN 13 : 3527334645
Total Pages : 402 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Analyzing Biomolecular Interactions by Mass Spectrometry by : Jeroen Kool

Download or read book Analyzing Biomolecular Interactions by Mass Spectrometry written by Jeroen Kool and published by John Wiley & Sons. This book was released on 2015-05-04 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomics and interactomics. The third and final part discusses other important technologies frequently employed in interaction studies, such as biosensors and microarrays. For pharmaceutical, analytical, protein, environmental and biochemists, as well as those working in pharmaceutical and analytical laboratories.

Two Dimensional Mass Spectrometric Separation and Identification of Complex Mixtures

Author : F. W. McLafferty
Publisher :
ISBN 13 :
Total Pages : 6 pages
Book Rating : 4.:/5 (227 download)

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Book Synopsis Two Dimensional Mass Spectrometric Separation and Identification of Complex Mixtures by : F. W. McLafferty

Download or read book Two Dimensional Mass Spectrometric Separation and Identification of Complex Mixtures written by F. W. McLafferty and published by . This book was released on 1982 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new technique of tandem mass spectrometry (MS/MS) has been investigated, in particular for the analysis of complex organic mixtures for trace components. Applicability, limitations, and improvements studied include those involving sensitivity, specificity, accuracy, speed, and identification of unknown components. The technique has been applied to important problems in targeted compound analysis, targeted class analysis, molecular structure determination, and unimolecular ion decomposition mechanisms. A unique tandem double-focusing mass spectrometer has been constructed, improved, and applied to these research problems. (Author).

Applications of Mass Spectrometry to Trace Analysis

Author : Sergio Facchetti
Publisher : Elsevier Science & Technology
ISBN 13 :
Total Pages : 340 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Applications of Mass Spectrometry to Trace Analysis by : Sergio Facchetti

Download or read book Applications of Mass Spectrometry to Trace Analysis written by Sergio Facchetti and published by Elsevier Science & Technology. This book was released on 1982 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Interpretation of MS-MS Mass Spectra of Drugs and Pesticides

Author : Wilfried M. A. Niessen
Publisher : John Wiley & Sons
ISBN 13 : 1119294258
Total Pages : 799 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Interpretation of MS-MS Mass Spectra of Drugs and Pesticides by : Wilfried M. A. Niessen

Download or read book Interpretation of MS-MS Mass Spectra of Drugs and Pesticides written by Wilfried M. A. Niessen and published by John Wiley & Sons. This book was released on 2017-01-09 with total page 799 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of the interpretation of LC–MS–MS mass spectra of 1300 drugs and pesticides Provides a general discussion on the fragmentation of even-electron ions (protonated and deprotonated molecules) in both positive-ion and negative-ion modes This is the reference book for the interpretation of MS–MS mass spectra of small organic molecules Covers related therapeutic classes of compounds such as drugs for cardiovascular diseases, psychotropic compounds, drugs of abuse and designer drugs, antimicrobials, among many others Covers general fragmentation rule as well as specific fragmentation pathways for many chemical functional groups Gives an introduction to MS technology, mass spectral terminology, information contained in mass spectra, and to the identification strategies used for different types of unknowns

Principles of Forensic Toxicology

Author : Barry Levine
Publisher : Amer. Assoc. for Clinical Chemistry
ISBN 13 : 9781890883874
Total Pages : 406 pages
Book Rating : 4.8/5 (838 download)

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Book Synopsis Principles of Forensic Toxicology by : Barry Levine

Download or read book Principles of Forensic Toxicology written by Barry Levine and published by Amer. Assoc. for Clinical Chemistry. This book was released on 2003 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Determination of Trace Elements

Author : Zeev B. Alfassi
Publisher : John Wiley & Sons
ISBN 13 : 3527615768
Total Pages : 622 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Determination of Trace Elements by : Zeev B. Alfassi

Download or read book Determination of Trace Elements written by Zeev B. Alfassi and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: The best way to determine trace elements! This easy-to-use handbook guides the reader through the maze of all modern analytical operations. Each method is described by an expert in the field. The book highlights the advantages and disadvantages of individual techniques and enables pharmacologists, environmentalists, material scientists, and food industry to select a judicious procedure for their trace element analysis.

Organic Trace Analysis

Author : Reinhard Nießner
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110441152
Total Pages : 370 pages
Book Rating : 4.1/5 (14 download)

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Book Synopsis Organic Trace Analysis by : Reinhard Nießner

Download or read book Organic Trace Analysis written by Reinhard Nießner and published by Walter de Gruyter GmbH & Co KG. This book was released on 2017-08-07 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Organic Trace Analysis" presents the basics of trace analysis, from sample preparation to the measurement: Students are introduced to statistical evaluation, quality control technologies, sampling and preparation of organic traces, as well as to enrichment and separation of samples. Spectroscopic techniques as chromatography, capillary electrophoresis, mass spectrometry, and receptor-based bioanalysis are presented in detail.

Mass Spectrometry in Medicinal Chemistry

Author : Klaus Wanner
Publisher : John Wiley & Sons
ISBN 13 : 352761091X
Total Pages : 460 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Mass Spectrometry in Medicinal Chemistry by : Klaus Wanner

Download or read book Mass Spectrometry in Medicinal Chemistry written by Klaus Wanner and published by John Wiley & Sons. This book was released on 2007-06-27 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug design and analysis of multiple ligand-target interactions. The ready reference opens with a general introduction to the use of mass spectrometry in pharmaceutical screening, followed by a detailed description of recently developed analytical systems for use in the pharmaceutical laboratory. Applications range from simple binding assays to complex screens of biological activity and systems containing multiple targets or ligands -- all highly relevant techniques in the early stages in drug discovery, from target characterization to hit and lead finding.

Mass Spectrometry

Author : Edmond de Hoffmann
Publisher : Wiley
ISBN 13 : 9780471485650
Total Pages : 420 pages
Book Rating : 4.4/5 (856 download)

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Book Synopsis Mass Spectrometry by : Edmond de Hoffmann

Download or read book Mass Spectrometry written by Edmond de Hoffmann and published by Wiley. This book was released on 2001-10-10 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offers a complete overview of the principles, theories and key applications of modern mass spectrometry in this introductory textbook. Following on from the highly successful first edition, this edition is extensively updated including new techniques and applications. All instrumental aspects of mass spectrometry are clearly and concisely described; sources, analysers and detectors. * Revised and updated * Numerous examples and illustrations are combined with a series of exercises to help encourage student understanding * Includes biological applications, which have been significantly expanded and updated * Also includes coverage of ESI and MALDI

Liquid Chromatography

Author : Salvatore Fanali
Publisher : Elsevier
ISBN 13 : 0128093447
Total Pages : 840 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Liquid Chromatography by : Salvatore Fanali

Download or read book Liquid Chromatography written by Salvatore Fanali and published by Elsevier. This book was released on 2017-06-23 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liquid Chromatography: Applications, Second Edition,is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their knowledge of the wide variety of applications in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more. This second edition addresses these new developments with updated chapters from the most expert researchers in the field. Emphasizes the integration of chromatographic methods and sample preparation Explains how liquid chromatography is used in different industrial sectors Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making

Scientific and Technical Aerospace Reports

Author :
Publisher :
ISBN 13 :
Total Pages : 1020 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Scientific and Technical Aerospace Reports by :

Download or read book Scientific and Technical Aerospace Reports written by and published by . This book was released on 1988 with total page 1020 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Inorganic Mass Spectrometry

Author : Sabine Becker
Publisher : John Wiley & Sons
ISBN 13 : 9780470517208
Total Pages : 514 pages
Book Rating : 4.5/5 (172 download)

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Book Synopsis Inorganic Mass Spectrometry by : Sabine Becker

Download or read book Inorganic Mass Spectrometry written by Sabine Becker and published by John Wiley & Sons. This book was released on 2008-02-28 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing an exhaustive review of this topic, Inorganic Mass Spectrometry: Principles and Applications provides details on all aspects of inorganic mass spectrometry, from a historical overview of the topic to the principles and functions of mass separation and ion detection systems. Offering a comprehensive treatment of inorganic mass spectrometry, topics covered include: Recent developments in instrumentation Developing analytical techniques for measurements of trace and ultratrace impurities in different materials This broad textbook in inorganic mass spectrometry, presents the most important mass spectrometric techniques used in all fields of analytical chemistry. By covering recent developments and advances in all fields of inorganic mass spectrometry, this text provides researchers and students with information to answer any questions on this topic as well as providing the basic fundamentals for understanding this potentially complex, but increasingly relevant subject.