Technical Report on Toxicology and Carcinogenesis Studies of Cumene (CAS No. 98-82-8) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)

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Publisher : DIANE Publishing
ISBN 13 : 1437914543
Total Pages : 206 pages
Book Rating : 4.4/5 (379 download)

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Book Synopsis Technical Report on Toxicology and Carcinogenesis Studies of Cumene (CAS No. 98-82-8) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) by : P. C. Chan

Download or read book Technical Report on Toxicology and Carcinogenesis Studies of Cumene (CAS No. 98-82-8) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) written by P. C. Chan and published by DIANE Publishing. This book was released on 2009-09 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cumene is produced in a modified Friedel-Crafts reaction process. Cumene is the principal chemical used in the production of phenol and acetone. Cumene is used: as a thinner; as a constituent of some petroleum-based solvents; in gasoline blending, diesel fuel, and high-octane aviation fuel; and as a raw material for peroxides and oxidation catalysts. Because cumene is a good solvent for fats and resins, it has been suggested as a replacement for benzene in many industrial applications. Cumene occurs naturally in petroleum and in a variety of foodstuffs. Cumene was nominated for study because of its high production volume, presence in gasoline and other fuels, potential for human exposure, and lack of existing carcinogenecity test data. Illus.

Toxicology and Carcinogenesis Studies of Decalin

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Publisher :
ISBN 13 : 9780756749453
Total Pages : 315 pages
Book Rating : 4.7/5 (494 download)

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Book Synopsis Toxicology and Carcinogenesis Studies of Decalin by : P. C. Chan

Download or read book Toxicology and Carcinogenesis Studies of Decalin written by P. C. Chan and published by . This book was released on 2005-08 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Decalin is used as an industrial solvent for naphthalene, fats, resins, oils, & waxes. It is also used in lacquers, paints, & varnishes; shoe polishes & floor waxes; & motor fuels & lubricants. Other applications include use as a paint thinner & remover, a patent fuel in stoves, a high-density fuel in submarine-launched cruise missile systems, & in stain removal & cleaning machinery. Decalin was nominated for study by the Nat. Cancer Institute because of its chemical structure, its potential for consumer exposure, & a lack of adequate testing of the chemical. Illustrations.

Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances

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Publisher : World Health Organization
ISBN 13 :
Total Pages : 696 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 1999 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allyl isothiocyanate; ortho-Anisidine; Atrazine; Butyl benzyl phthalate; Chloroform; Chlorothalonil;Cyclamates;Dichlorobenzenes;Hexachlorobutadiene; Hexachloroethane; d-Limonene; Melamine; Methyl tert-butyl ether; Nitrilotriaceticacid andits salts;Paracetamol; ortho-Phenylphenol and its sodium salt; Potassium bromate ;Quercetin; Saccharin and its salts;Simazine

Cancer Risk Assessment

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Publisher : John Wiley & Sons
ISBN 13 : 1118035127
Total Pages : 727 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Cancer Risk Assessment by : Ching-Hung Hsu

Download or read book Cancer Risk Assessment written by Ching-Hung Hsu and published by John Wiley & Sons. This book was released on 2010-12-08 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a weight-of-the-evidence approach, cancer risk assessment indentifies hazards, determines dose-response relationships, and assesses exposure to characterize the true risk. This book focuses on the quantitative methods for conducting chemical cancer risk assessments for solvents, metals, mixtures, and nanoparticles. It links these to the basic toxicology and biology of cancer, along with the impacts on regulatory guidelines and standards. By providing insightful perspective, Cancer Risk Assessment helps researchers develop a discriminate eye when it comes to interpreting data accurately and separating relevant information from erroneous.

Technical Report Series

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Publisher :
ISBN 13 :
Total Pages : 208 pages
Book Rating : 4.:/5 (9 download)

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Book Synopsis Technical Report Series by :

Download or read book Technical Report Series written by and published by . This book was released on 2011 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Proctor and Hughes' Chemical Hazards of the Workplace

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Publisher : John Wiley & Sons
ISBN 13 : 9780471268833
Total Pages : 808 pages
Book Rating : 4.2/5 (688 download)

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Book Synopsis Proctor and Hughes' Chemical Hazards of the Workplace by : Gloria J. Hathaway

Download or read book Proctor and Hughes' Chemical Hazards of the Workplace written by Gloria J. Hathaway and published by John Wiley & Sons. This book was released on 2014-12-03 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: The indispensable resource for health professionals on potentially unsafe chemicals--now fully updated Proctor and Hughes' Chemical Hazards of the Workplace, Fifth Edition provides a comprehensive reference text for health professionals who need toxicology data on chemicals that may be encountered in various work settings. Building on the success of the Fourth Edition-already a standard text-this new edition updates and revises the more than 600 entries of that text, and also adds monographs on new compounds. Introductory chapters cover toxicological concepts, clinical manifestations of exposure, the diagnosis of occupational disease, and industrial hygiene aspects of chemical exposures. The rest of the text consists of more than 625 alphabetically arranged entries on individual compounds, each of which includes: * Chemical formula * CAS number * 2003 ACGIH (American Conference of Government Industrial Hygienists) threshold limit value * Synonyms * Physical properties * Sources of exposure * Routes of exposure * Toxicological data The toxicological data includes both acute and chronic effects, especially as related to any known exposure levels. The data emphasizes human studies and cases over animal data whenever sufficient information is available, and addresses any known carcinogenic, mutagenic, fetotoxic, or other reproductive effects. Clinical information is presented in a succinct narrative form to aid in understanding. Easy to use, in-depth, and comprehensive, Proctor and Hughes' Chemical Hazards of the Workplace, Fifth Edition offers occupational health physicians, nurses, industrial hygienists, and other safety professionals an invaluable and up-to-date resource.

Toxicological Profile for Polycyclic Aromatic Hydrocarbons

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Publisher :
ISBN 13 :
Total Pages : 500 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicological Profile for Polycyclic Aromatic Hydrocarbons by :

Download or read book Toxicological Profile for Polycyclic Aromatic Hydrocarbons written by and published by . This book was released on 1995 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Carcinogens and Anticarcinogens in the Human Diet

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Publisher : National Academies Press
ISBN 13 : 0309053919
Total Pages : 434 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Carcinogens and Anticarcinogens in the Human Diet by : National Research Council

Download or read book Carcinogens and Anticarcinogens in the Human Diet written by National Research Council and published by National Academies Press. This book was released on 1996-03-12 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.

Nongenotoxic Carcinogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 3662030225
Total Pages : 279 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Nongenotoxic Carcinogenesis by : A. Cockburn

Download or read book Nongenotoxic Carcinogenesis written by A. Cockburn and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: "What is a nongenotoxic carcinogen?" This question recurred through out the Ernst Schering Research Foundation Workshop on nongeno toxic carcinogenesis, underlining the complexity of the topic. The clarity of the view that all carcinogens act by mutating DNA, origin ally advocated by Bruce Ames nearly 20 years ago, has been clouded by the increasing numbers of compounds which are not genotoxic but which nevertheless can cause cancer. There is an urgent need to in crease our understanding of these compounds so that their risks can be evaluated realistically and decisions made from a position of knowl edge and strength, rather than in fear of the unknown. A nongenotoxic carcinogen can be defined as a compound which causes cancer, but which does not cause damage to DNA as its primary biological activity. This negative definition covers a range of carci nogens acting through a variety of mechanisms. Such chemicals often produce tumours only in a single organ species, and there are a few common locations which are affected most often. For example, in male rats, certain carcinogens bind to az globulin to form a complex which 11 accumulates in the kidney tubular cells, which is followed by necrosis and compensatory cell proliferation leading the neoplasia. Other com mon mechanisms include hormonal imbalance resulting in thyroid tu mours or peroxisome proliferation resulting in liver cancer. These and other examples are studied in some detail in the papers of this book.

NTP, Current Directions and Evolving Strategies

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Publisher :
ISBN 13 :
Total Pages : 90 pages
Book Rating : 4.:/5 (9 download)

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Book Synopsis NTP, Current Directions and Evolving Strategies by : National Toxicology Program (U.S.)

Download or read book NTP, Current Directions and Evolving Strategies written by National Toxicology Program (U.S.) and published by . This book was released on 2001 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Annual Plan for Fiscal Year ...

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Publisher :
ISBN 13 :
Total Pages : 984 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Annual Plan for Fiscal Year ... by : National Toxicology Program (U.S.)

Download or read book Annual Plan for Fiscal Year ... written by National Toxicology Program (U.S.) and published by . This book was released on 1991 with total page 984 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Patty's Toxicology, 6 Volume Set

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Publisher : John Wiley & Sons
ISBN 13 : 0470410817
Total Pages : 5872 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Patty's Toxicology, 6 Volume Set by : Eula Bingham

Download or read book Patty's Toxicology, 6 Volume Set written by Eula Bingham and published by John Wiley & Sons. This book was released on 2012-07-31 with total page 5872 pages. Available in PDF, EPUB and Kindle. Book excerpt: Featuring the improved format used in the 5th edition, this updated set presents, in logical groupings, comprehensive toxicological data for industrial compounds, including CAS numbers, physical and chemical properties, exposure limits, and biological tolerance values for occupational exposures, making it essential for toxicologists and industrial hygienists. This edition has about 40% new authors who have brought a new and international perspective to interpreting industrial toxicology, and discusses new subjects such as nanotechnology, flavorings and the food industry, reactive chemical control to comprehensive chemical policy, metalworking fluids, and pharmaceuticals.

Environmental Health Perspectives

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Publisher :
ISBN 13 :
Total Pages : 1520 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Environmental Health Perspectives by :

Download or read book Environmental Health Perspectives written by and published by . This book was released on 2000 with total page 1520 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicological Profile for Dichlorobenzenes

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Publisher :
ISBN 13 :
Total Pages : 500 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicological Profile for Dichlorobenzenes by : United States. Agency for Toxic Substances and Disease Registry

Download or read book Toxicological Profile for Dichlorobenzenes written by United States. Agency for Toxic Substances and Disease Registry and published by . This book was released on 2006 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt:

National Cancer Institute Carcinogenesis Technical Report Series

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Publisher :
ISBN 13 :
Total Pages : 174 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis National Cancer Institute Carcinogenesis Technical Report Series by :

Download or read book National Cancer Institute Carcinogenesis Technical Report Series written by and published by . This book was released on 1976 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicology of the Kidney

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Publisher : CRC Press
ISBN 13 : 9780881678857
Total Pages : 588 pages
Book Rating : 4.6/5 (788 download)

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Book Synopsis Toxicology of the Kidney by : Jerry B. Hook

Download or read book Toxicology of the Kidney written by Jerry B. Hook and published by CRC Press. This book was released on 1993-06-30 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition provides a synthesis of recent research on the mechanisms of chemically-induced kidney injury. The text includes a review of current concepts of clinical nephrotoxicity and renal failure, and mechanisms of specific classes of nephrotoxic drugs and environmental chemicals.

Government Reports Announcements & Index

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Publisher :
ISBN 13 :
Total Pages : 1020 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis Government Reports Announcements & Index by :

Download or read book Government Reports Announcements & Index written by and published by . This book was released on 1986-07 with total page 1020 pages. Available in PDF, EPUB and Kindle. Book excerpt: