Toxicological Profile For Perfluoroalkyls

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Toxicological Profile for Perfluoroalkyls

Author :
Publisher :
ISBN 13 :
Total Pages : 412 pages
Book Rating : 4.:/5 (9 download)

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Download or read book Toxicological Profile for Perfluoroalkyls written by and published by . This book was released on 2009 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This toxicological profile for perfluoroalkyls was prepared consistent with guidelines developed by the Agency for Toxic Substances and Disease Registry (ATSDR) and the Environmental Protection Agency (EPA) for the preparation of toxicological profiles. The original guidelines were published in the Federal Register on April 17, 1987. While Perfluoroalkyls are not found on the ATSDR list of Priority Hazardous Substances, ATSDR has determined that a profile for these substances was necessary because data indicate that some perfluoroalkyls are found in the blood of the U.S. general population and in the environment. The agency also determined that it was important to characterize the current available information regarding the health effects from exposure in order to support and inform public health responses and activities by ATSDR and other." -- p. v

Toxicological Profile for Perfluoroalkyls

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Publisher :
ISBN 13 :
Total Pages : 993 pages
Book Rating : 4.:/5 (125 download)

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Download or read book Toxicological Profile for Perfluoroalkyls written by and published by . This book was released on 2021 with total page 993 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicological Profile for Perfluoroalkyls: Draft for Public Comment

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Download or read book Toxicological Profile for Perfluoroalkyls: Draft for Public Comment written by and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Draft Toxicological Profile for Perfluoroalkyls

Author :
Publisher :
ISBN 13 :
Total Pages : 364 pages
Book Rating : 4.:/5 (819 download)

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Download or read book Draft Toxicological Profile for Perfluoroalkyls written by and published by . This book was released on 2009 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances

Author : Jamie C. DeWitt
Publisher : Humana Press
ISBN 13 : 3319155180
Total Pages : 500 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances by : Jamie C. DeWitt

Download or read book Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances written by Jamie C. DeWitt and published by Humana Press. This book was released on 2015-04-14 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. This book includes chapters on human and wildlife exposure/body burdens, reviews of metabolism and toxicological effects by organ system/developmental stage and aspects of PFAS toxicity that are driving PFAS research and regulatory oversight. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances provide critical assessments of the most controversial topics surrounding toxicological evaluation of PFASs to give readers an expert perspective on the issues. Emphasis is placed on the integration of modes and mechanisms of action with functional endpoints that are relevant to human and wildlife health. This book will be a useful resource for toxicologists, environmental chemists, risk assessors and researchers with an interest in the class of compounds known as perfluoroalkyl and polyfluoroalkyl substances.

Perfluoroalkyl Substances in the Environment

Author : David M. Kempisty
Publisher : CRC Press
ISBN 13 : 0429945035
Total Pages : 498 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Perfluoroalkyl Substances in the Environment by : David M. Kempisty

Download or read book Perfluoroalkyl Substances in the Environment written by David M. Kempisty and published by CRC Press. This book was released on 2018-08-06 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Per- and polyfluorinated alkyl substances (PFAS), often referred to as per- (and poly) fluorinated compounds (PFCs), have been used for years in many everyday3⁄4 and some lifesaving3⁄4 products. However, their use has been linked to adverse health effects in humans, a problem compounded by their persistence in the environment. This book discusses the various challenges of PFAS in our environment today, including their historical use as well as their chemical and toxicological properties. It also presents robust discussion of analytical challenges and special considerations in sampling. The work goes on to give practical recommendations for dealing with these compounds in today's dynamic regulatory landscape and includes several chapters on various remediation techniques. Key Features: Comprehensive overview of per- and polyfluorinated alkyl substances (PFAS) historical use and chemical/physical properties which help us understand their persistence, transport, and transformation pathways in the environment In-depth analysis of PFAS toxicology Detailed descriptions of conventional and state-of-the-art remediation technologies Practical recommendations for dealing with PFAS in a dynamic regulatory landscape Robust discussion of important sampling and analytical considerations Perfluoroalkyl Substances in the Environment: Theory, Practice, and Innovation explores the challenges across the topical areas of regulation and management, toxicology, environmental remediation, and analytical sampling and analysis.Readers will find this text helpful in understanding complexities associated with PFAS and informing management strategies to effectively protect this and future generations.

Mammalian Toxicology

Author : Mohamed Abou-Donia
Publisher : John Wiley & Sons
ISBN 13 : 1119940419
Total Pages : 716 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Mammalian Toxicology by : Mohamed Abou-Donia

Download or read book Mammalian Toxicology written by Mohamed Abou-Donia and published by John Wiley & Sons. This book was released on 2015-05-04 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mammalian Toxicology surveys chemical agents and examines how such chemicals impact on human health, emphasizing the importance in minimizing environmental exposure to chemical and physical hazards in our homes, communities and workplaces through such media as contaminated water, soil and air. Starting with the basic principles on a wide range of toxic agents, this textbook describes how they enter the body, their mechanisms of action once inside, and strategies for diagnosis, prevention and treatment. Topics covered include: General principles of toxicology: pharmacological and toxicological principles underpinning the study of toxicology, risk assessments and mechanisms of cell death Disposition: routes of chemical exposures, entry into the body and various tissues, storage, metabolic biotransformation and elimination, with examples from various toxicants. Toxic agents: the occurrences, disposition in the body, health effects, toxic mechanisms, antidotes and treatments of a range of agents including pesticides, metals, solvents, gases, nanomaterials, food components and additives, pharmaceuticals, drugs of abuse, natural toxins, endocrine disruptors, radiation, and warfare weapons. Toxic effects: including neurotoxicity, developmental toxicity, immunotoxicity, teratogenecity, male and female reproductive toxicity, mutagenecity, carcinogenicity, pulmonary toxicity, cardiovascular toxicity, hepatotoxicity, gastrointestinal toxicity and cardiovascular toxicity Toxicology and society: epidemiological studies of chemical-induced diseases in human populations, and a vision for toxicology in the 21st century. Mammalian Toxicology is an essential primer for students of toxicology, biochemistry, biology, medicine and chemistry. It is also appropriate for professional toxicologists in research or regulatory affairs, and anyone who needs to understand the adverse effects of toxic agents on the human body.

The cost of inaction

Author : Gretta Goldenman
Publisher : Nordic Council of Ministers
ISBN 13 : 9289360658
Total Pages : 194 pages
Book Rating : 4.2/5 (893 download)

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Book Synopsis The cost of inaction by : Gretta Goldenman

Download or read book The cost of inaction written by Gretta Goldenman and published by Nordic Council of Ministers. This book was released on 2019-03-17 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: PFAS (per and polyfluoroalkylsubstances) are known to be extremely difficult to degrade in the environment and to be bioaccumulative and toxic. Exposure to PFAS is suspected to increase the risk of adverse health effects, such as impacts on the thyroid gland, the liver, fat metabolism and the immune system. This study estimates the socioeconomic costs that may result from impacts on human health and the environment from the use of PFAS. Better awareness of the costs and problems associated with PFAS exposure will assist decision-makers and the general public to make more efficient and timely risk management decisions. Findings indicate that the costs are substantial, with annual health-related costs estimated to 2.8 – 4.6 billion EUR for the Nordic countries and 52 – 84 billion EUR for all EEA countries. Overall non-health costs are estimated at 46 million – 11 billion EUR for the Nordic countries.Upon request the excel spreadsheets used for the monetarisation and valuation in this report can also be provided along with a guidance on how to use the estimation of costs for value transfer. Please contact any of the consultants or members of the steering group from the Swedish Chemicals Agency or the Danish Environmental Protection Agency if you are interested in receiving these excel spreadsheets.

Emerging Contaminants Handbook

Author : Caitlin H. Bell
Publisher : CRC Press
ISBN 13 : 1351665073
Total Pages : 439 pages
Book Rating : 4.3/5 (516 download)

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Book Synopsis Emerging Contaminants Handbook by : Caitlin H. Bell

Download or read book Emerging Contaminants Handbook written by Caitlin H. Bell and published by CRC Press. This book was released on 2019-01-15 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term "emerging contaminants" and its multiple variants has come to refer to unregulated compounds discovered in the environment that are also found to represent a potential threat to human and ecological receptors. Such contaminants create unique and considerable challenges as the push to address them typically outpaces the understanding of their toxicity, their need for regulation, their occurrence, and techniques for treating the environmental media they affect. With these challenges in mind, this handbook serves as a primer regarding the topic of emerging contaminants, with current and practical information to help support the goal of protection where they are encountered. Features Explores the definition, identification, and life cycle of emerging contaminants. Reviews current information on sources, toxicology, regulation, and new tools for characterization and treatment of: 1,4-Dioxane (mature in its emerging contaminant life cycle) Per- and polyfluoroalkyl substances (PFASs; a newer group of emerging contaminant) Hexavalent chromium (former emerging contaminant with evolving science) 1,2,3-Trichloropropane (progressing in its emerging contaminant life cycle) Provides thoughts on opportunities in managing emerging contaminants to help balance uncertainty, compress life cycle, and optimize outcomes.

Toxicological Profile for Bromomethane

Author :
Publisher :
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicological Profile for Bromomethane by :

Download or read book Toxicological Profile for Bromomethane written by and published by . This book was released on 1992 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Polyfluorinated Chemicals and Transformation Products

Author : Thomas P. Knepper
Publisher : Springer Science & Business Media
ISBN 13 : 3642218717
Total Pages : 183 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Polyfluorinated Chemicals and Transformation Products by : Thomas P. Knepper

Download or read book Polyfluorinated Chemicals and Transformation Products written by Thomas P. Knepper and published by Springer Science & Business Media. This book was released on 2011-09-21 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to their unparalleled effectiveness and efficiency, polyfluorinated chemicals (PFC) have become essential in numerous technical applications. However, many PFCs brought to market show limited biodegradability, and their environmental persistence combined with toxic and bioaccumulative potential have become a matter of concern in some instances. This volume highlights the synthesis of PFCs, focusing on substances with improved application and environmental properties, which are a challenge for synthetic chemists. Further, modern mass spectrometric techniques for the detection and identification of biotransformation products of PFCs are described. The sorption and leaching behavior of PFC in soil is also addressed in order to predict their fate in the environment. Several contributions discuss the monitoring of PFCs in European surface, ground and drinking waters, treatment options for PFC removal from drinking water, occurrence in food, and the human biomonitoring of PFCs.

Perfluoroalkyl Substances

Author : Bruno Améduri
Publisher : Royal Society of Chemistry
ISBN 13 : 1839165685
Total Pages : 651 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Perfluoroalkyl Substances by : Bruno Améduri

Download or read book Perfluoroalkyl Substances written by Bruno Améduri and published by Royal Society of Chemistry. This book was released on 2022-08-15 with total page 651 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title provides a balanced overview of the field, from basic synthesis through to applications, why some current PFASs are and may remain the right substance for the job, as well as addressing the challenges and alternatives.

Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS)

Author : Mark S. Johnson
Publisher : CRC Press
ISBN 13 : 1000375889
Total Pages : 122 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) by : Mark S. Johnson

Download or read book Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) written by Mark S. Johnson and published by CRC Press. This book was released on 2021-04-22 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding Risk to Wildlife from Exposures to Per- and Polyfluorinated Alkyl Substances (PFAS) provides the most recent summary of toxicity data relevant to mammals, birds, reptiles, and amphibians, and provides values for use in risk assessment applications. Predicting the bioaccumulation of PFAS in terrestrial wildlife (including humans) has proven to be extremely complex. As a group, PFAS act differently than traditional non-ionic organic molecules, where PFAS can break down and reform, whereas some are demonstrated to be extremely persistent. Where sufficient data are provided, this book establishes toxicity reference values (TRVs), which are derived to assist in characterizing environmental sources of contamination and making risk-based decisions. Features: Provides toxicity reference values (TRVs) for vertebrates (mammals, birds, amphibians) for PFAS, where sufficient data are available, and includes objective supporting background information. Assigns a level of confidence to each TRV to provide the risk assessor with an understanding of the relative uncertainty associated with each value. Presents toxicity data in the formats of scatter diagrams and tables for quick review and assessment. Provides TRVs relevant for screening and decision making This book serves as a useful aid for risk assessors and managers in those industries that have sites contaminated with PFAS, consultants tasked with evaluating risks at such sites, and staff at regulatory agencies at various governmental levels, who need to know how much contamination is considered safe for wildlife. It will also appeal to researchers with an interest in filling the gaps in the current toxicological data for PFAS exposure.

Toxicological Profile for 1,3-butadiene

Author :
Publisher :
ISBN 13 :
Total Pages : 142 pages
Book Rating : 4.3/5 (91 download)

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Download or read book Toxicological Profile for 1,3-butadiene written by and published by . This book was released on 1992 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Indoor Air Quality

Author : Hermann Fromme
Publisher : Springer Nature
ISBN 13 : 303140078X
Total Pages : 587 pages
Book Rating : 4.0/5 (314 download)

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Book Synopsis Indoor Air Quality by : Hermann Fromme

Download or read book Indoor Air Quality written by Hermann Fromme and published by Springer Nature. This book was released on 2023-11-29 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive and detailed overview of indoor pollution, covering the main contaminants in the indoor environment – air and dust, the health aspects of exposure, and different possibilities for a risk assessment. The book outlines the chemical substances and physical and biological factors that occur more frequently indoors, which are of health significance, or for which only limited information on their occurrence indoors is available to date. It also provides guidance to identify where problems may arise in the future and where data is missing for a valid exposure and risk assessment as well as for consequent risk management. Written by a highly recognized and experienced medical expert in the field, the book starts with an introduction to the indoor environment, including topics such as indoor environmental quality and health, indoor climate, sampling of indoor pollutants, and measures to improve indoor air quality. The author then delves into the fundamentals of exposure assessment and special exposure indoor situations, followed by in-depth coverage of the health aspects, and indoor air occurrence of several substances such as volatile organic compounds, very volatile organic compounds, semi-volatile organic compounds, and particulate matters and fibers. Particular attention is given to bioaerosols like mold, microbial volatile organic compounds, mycotoxins, and viruses. Readers will also find chapters devoted to the main health aspects and indoor occurrence of inorganic gases, radon and metals, and smoking. The book closes with a chapter on risk assessment, in which readers will learn more about the basics of risk assessment, key points and processes of a health evaluation, and guidance for assessing indoor air contamination. This book is a unique compilation of the current worldwide exposure situation in private and public indoor spaces, and an important reference for researchers that are willing to assess the rising burden of disease and potential causes behind degraded indoor air quality. Scientists, students, and policymakers interested in the fields of medicine and environmental sciences will understand the appeal of this book.

Toxicological Profile for Trichloroethylene

Author :
Publisher :
ISBN 13 :
Total Pages : 340 pages
Book Rating : 4.:/5 (321 download)

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Download or read book Toxicological Profile for Trichloroethylene written by and published by . This book was released on 1997 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Emerging Contaminants in the Environment

Author : Hemen Sarma
Publisher : Elsevier
ISBN 13 : 032385981X
Total Pages : 713 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Emerging Contaminants in the Environment by : Hemen Sarma

Download or read book Emerging Contaminants in the Environment written by Hemen Sarma and published by Elsevier. This book was released on 2022-01-08 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging Contaminants in the Environment: Challenges and Sustainable Practices covers all aspects of emerging contaminants in the environment, from basic understanding to different types of emerging contaminants and how these threaten organisms, their environmental fate studies, detection methods, and sustainable practices of dealing with contaminants. Emerging contaminant remediation is a pressing need due to the ever-increasing pollution in the environment, and it has gained a lot of scientific and public attention due to its high effectiveness and sustainability. The discussions in the book on the bioremediation of these contaminants are covered from the perspective of proven technologies and practices through case studies and real-world data. One of the main benefits of this book is that it summarizes future challenges and sustainable solutions. It can, therefore, become an effective guide to the elimination (through sustainable practices) of emerging contaminants. At the back of these explorations on sustainable bioremediation of emerging contaminants lies the set of 17 goals articulated by the United Nations in its 2030 Agenda for Sustainable Development, adopted by all its member states. This book provides academics, researchers, students, and practitioners interested in the detection and elimination of emerging contaminants from the environment, with the latest advances by leading experts in emerging contaminants the field of environmental sciences. Covers most aspects of the most predominant emerging contaminants in the environment, including in soil, air, and water Describes the occurrence of these contaminants, the problems they cause, and the sustainable practices to deal with the contaminants Includes data from case studies to provide real-world examples of sustainable practices and emerging contaminant remediation