Topological Data Analysis For Genomics And Evolution

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Topological Data Analysis for Genomics and Evolution

Author : Raul Rabadan
Publisher : Cambridge University Press
ISBN 13 : 1108757499
Total Pages : 522 pages
Book Rating : 4.1/5 (87 download)

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Book Synopsis Topological Data Analysis for Genomics and Evolution by : Raul Rabadan

Download or read book Topological Data Analysis for Genomics and Evolution written by Raul Rabadan and published by Cambridge University Press. This book was released on 2019-12-19 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology has entered the age of Big Data. A technical revolution has transformed the field, and extracting meaningful information from large biological data sets is now a central methodological challenge. Algebraic topology is a well-established branch of pure mathematics that studies qualitative descriptors of the shape of geometric objects. It aims to reduce comparisons of shape to a comparison of algebraic invariants, such as numbers, which are typically easier to work with. Topological data analysis is a rapidly developing subfield that leverages the tools of algebraic topology to provide robust multiscale analysis of data sets. This book introduces the central ideas and techniques of topological data analysis and its specific applications to biology, including the evolution of viruses, bacteria and humans, genomics of cancer, and single cell characterization of developmental processes. Bridging two disciplines, the book is for researchers and graduate students in genomics and evolutionary biology as well as mathematicians interested in applied topology.

Topological Data Analysis for Genomics and Evolution

Author : Raul Rabadan
Publisher : Cambridge University Press
ISBN 13 : 1107159547
Total Pages : 521 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis Topological Data Analysis for Genomics and Evolution by : Raul Rabadan

Computational Topology for Data Analysis

Author : Tamal Krishna Dey
Publisher : Cambridge University Press
ISBN 13 : 1009103199
Total Pages : 456 pages
Book Rating : 4.0/5 (91 download)

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Book Synopsis Computational Topology for Data Analysis by : Tamal Krishna Dey

Download or read book Computational Topology for Data Analysis written by Tamal Krishna Dey and published by Cambridge University Press. This book was released on 2022-03-10 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topological data analysis (TDA) has emerged recently as a viable tool for analyzing complex data, and the area has grown substantially both in its methodologies and applicability. Providing a computational and algorithmic foundation for techniques in TDA, this comprehensive, self-contained text introduces students and researchers in mathematics and computer science to the current state of the field. The book features a description of mathematical objects and constructs behind recent advances, the algorithms involved, computational considerations, as well as examples of topological structures or ideas that can be used in applications. It provides a thorough treatment of persistent homology together with various extensions – like zigzag persistence and multiparameter persistence – and their applications to different types of data, like point clouds, triangulations, or graph data. Other important topics covered include discrete Morse theory, the Mapper structure, optimal generating cycles, as well as recent advances in embedding TDA within machine learning frameworks.

Adaptive Evolution of Genes and Genomes

Author : Austin L. Hughes
Publisher : Oxford University Press, USA
ISBN 13 : 9780195116267
Total Pages : 286 pages
Book Rating : 4.1/5 (162 download)

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Book Synopsis Adaptive Evolution of Genes and Genomes by : Austin L. Hughes

Download or read book Adaptive Evolution of Genes and Genomes written by Austin L. Hughes and published by Oxford University Press, USA. This book was released on 1999 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: It will be an invaluable tool for anyone interested or working in molecular or evolutionary biology, and for those studying the implications of our rapidly increasing knowledge of the genomes of organisms."--BOOK JACKET.

Topological Data Analysis with Applications

Author : Gunnar Carlsson
Publisher : Cambridge University Press
ISBN 13 : 1108838650
Total Pages : 233 pages
Book Rating : 4.1/5 (88 download)

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Book Synopsis Topological Data Analysis with Applications by : Gunnar Carlsson

Statistical Theory and Methods for Evolutionary Genomics

Author : Xun Gu
Publisher : OUP Oxford
ISBN 13 : 0199213267
Total Pages : 272 pages
Book Rating : 4.1/5 (992 download)

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Book Synopsis Statistical Theory and Methods for Evolutionary Genomics by : Xun Gu

Download or read book Statistical Theory and Methods for Evolutionary Genomics written by Xun Gu and published by OUP Oxford. This book was released on 2010-11-04 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summarises the statistical framework of evolutionary genomics, and illustrates how statistical modelling and testing can enhance our understanding of functional genomic evolution.

Essentials of Topology with Applications

Author : Steven G. Krantz
Publisher : CRC Press
ISBN 13 : 1420089757
Total Pages : 422 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Essentials of Topology with Applications by : Steven G. Krantz

Download or read book Essentials of Topology with Applications written by Steven G. Krantz and published by CRC Press. This book was released on 2009-07-28 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brings Readers Up to Speed in This Important and Rapidly Growing AreaSupported by many examples in mathematics, physics, economics, engineering, and other disciplines, Essentials of Topology with Applications provides a clear, insightful, and thorough introduction to the basics of modern topology. It presents the traditional concepts of topological

Bioinformatics and Human Genomics Research

Author : Diego A. Forero
Publisher : CRC Press
ISBN 13 : 1000405672
Total Pages : 374 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Bioinformatics and Human Genomics Research by : Diego A. Forero

Download or read book Bioinformatics and Human Genomics Research written by Diego A. Forero and published by CRC Press. This book was released on 2021-12-22 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in human and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide expression studies and genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.

First Concepts of Topology

Author : William G. Chinn
Publisher : MAA
ISBN 13 : 0883856182
Total Pages : 170 pages
Book Rating : 4.8/5 (838 download)

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Book Synopsis First Concepts of Topology by : William G. Chinn

Download or read book First Concepts of Topology written by William G. Chinn and published by MAA. This book was released on 1966 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 150 problems and solutions.

The Bunyaviridae

Author : Richard M. Elliott
Publisher : Springer Science & Business Media
ISBN 13 : 1489913645
Total Pages : 351 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis The Bunyaviridae by : Richard M. Elliott

Download or read book The Bunyaviridae written by Richard M. Elliott and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this comprehensive reference, leading researchers examine the biology, molecular biology, and diseases of the Bunyaviridae, and provide up-to-date information on the genetic characterization and variations of this virus group. Chapters deal with the molecular biology of five genera: Bunyavirus, Hantavirus, Nairovirus, Phlebovirus, and Tospovirus. Chapters examine Bunyaviridae assembly and intracelluar protein transport as well as Bunyaviridae genetics. Contributors discuss the Bunyaviridae diseases, including the hantavirus pulmonary syndrome.

Bioinformatics and Data Analysis in Microbiology

Author : Özlem Taştan Bishop
Publisher : Caister Academic Press Limited
ISBN 13 : 9781908230393
Total Pages : 0 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Bioinformatics and Data Analysis in Microbiology by : Özlem Taştan Bishop

Download or read book Bioinformatics and Data Analysis in Microbiology written by Özlem Taştan Bishop and published by Caister Academic Press Limited. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides invaluable, up-to-date, and detailed information on bioinformatics data analysis with applications to microbiology. Includes useful bioinformatics tools, links to some wet-lab techniques, and explains different approaches to tackle a problem. It also covers challenges, limitations, applications and future trends.

Keywords in Evolutionary Biology

Author : Evelyn Fox Keller
Publisher : Harvard University Press
ISBN 13 : 9780674503137
Total Pages : 434 pages
Book Rating : 4.5/5 (31 download)

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Book Synopsis Keywords in Evolutionary Biology by : Evelyn Fox Keller

Download or read book Keywords in Evolutionary Biology written by Evelyn Fox Keller and published by Harvard University Press. This book was released on 1992 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: In science, more than elsewhere, a word is expected to mean what it says, nothing more, nothing less. But scientific discourse is neither different nor separable from ordinary language--meanings are multiple, ambiguities ubiquitous. Keywords in Evolutionary Biology grapples with this problem in a field especially prone to the confusion engendered by semantic imprecision. Written by historians, philosophers, and biologists--including, among others, Stephen Jay Gould, Diane Paul, John Beatty, Robert Richards, Richard Lewontin, David Sloan Wilson, Peter Bowler, and Richard Dawkins--these essays identify and explicate those terms in evolutionary biology which, though commonly used, are plagues by multiple concurrent and historically varying meanings. By clarifying these terms in their many guises, the editors Evelyn Fox Keller and Elisabeth Lloyd hope to focus attention on major scholarly problems in the field--problems sometimes obscured, sometimes reveals, and sometimes even created by the use of such equivocal words. "Competition," "adaptation," and "fitness," for instance, are among the terms whose multiple meaning have led to more than merely semantic debates in evolutionary biology. Exploring the complexity of keywords and clarifying their role in prominent issues in the field, this book will prove invaluable to scientists and philosophers trying to come to terms with evolutionary theory; it will also serve as a useful guide to future research into the way in which scientific language works.

Introduction to Topology

Author : Tej Bahadur Singh
Publisher : Springer
ISBN 13 : 9811369542
Total Pages : 452 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Introduction to Topology by : Tej Bahadur Singh

Download or read book Introduction to Topology written by Tej Bahadur Singh and published by Springer. This book was released on 2019-05-17 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topology is a large subject with several branches, broadly categorized as algebraic topology, point-set topology, and geometric topology. Point-set topology is the main language for a broad range of mathematical disciplines, while algebraic topology offers as a powerful tool for studying problems in geometry and numerous other areas of mathematics. This book presents the basic concepts of topology, including virtually all of the traditional topics in point-set topology, as well as elementary topics in algebraic topology such as fundamental groups and covering spaces. It also discusses topological groups and transformation groups. When combined with a working knowledge of analysis and algebra, this book offers a valuable resource for advanced undergraduate and beginning graduate students of mathematics specializing in algebraic topology and harmonic analysis.

Neural Networks and Genome Informatics

Author : C.H. Wu
Publisher : Elsevier
ISBN 13 : 9780080537375
Total Pages : 220 pages
Book Rating : 4.5/5 (373 download)

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Book Synopsis Neural Networks and Genome Informatics by : C.H. Wu

Download or read book Neural Networks and Genome Informatics written by C.H. Wu and published by Elsevier. This book was released on 2012-12-02 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive reference in the field of neural networks and genome informatics. The tutorial of neural network foundations introduces basic neural network technology and terminology. This is followed by an in-depth discussion of special system designs for building neural networks for genome informatics, and broad reviews and evaluations of current state-of-the-art methods in the field. This book concludes with a description of open research problems and future research directions.

Topological Data Analysis with Applications

Author : Gunnar Carlsson
Publisher : Cambridge University Press
ISBN 13 : 1108983944
Total Pages : 234 pages
Book Rating : 4.1/5 (89 download)

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Book Synopsis Topological Data Analysis with Applications by : Gunnar Carlsson

Download or read book Topological Data Analysis with Applications written by Gunnar Carlsson and published by Cambridge University Press. This book was released on 2021-12-16 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: The continued and dramatic rise in the size of data sets has meant that new methods are required to model and analyze them. This timely account introduces topological data analysis (TDA), a method for modeling data by geometric objects, namely graphs and their higher-dimensional versions: simplicial complexes. The authors outline the necessary background material on topology and data philosophy for newcomers, while more complex concepts are highlighted for advanced learners. The book covers all the main TDA techniques, including persistent homology, cohomology, and Mapper. The final section focuses on the diverse applications of TDA, examining a number of case studies drawn from monitoring the progression of infectious diseases to the study of motion capture data. Mathematicians moving into data science, as well as data scientists or computer scientists seeking to understand this new area, will appreciate this self-contained resource which explains the underlying technology and how it can be used.

Fundamentals of Topology

Author : Benjamin T. Sims
Publisher :
ISBN 13 :
Total Pages : 198 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Fundamentals of Topology by : Benjamin T. Sims

Download or read book Fundamentals of Topology written by Benjamin T. Sims and published by . This book was released on 1976 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bayesian Phylogenetics

Author : Ming-Hui Chen
Publisher : CRC Press
ISBN 13 : 1466500794
Total Pages : 398 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Bayesian Phylogenetics by : Ming-Hui Chen

Download or read book Bayesian Phylogenetics written by Ming-Hui Chen and published by CRC Press. This book was released on 2014-05-27 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering a rich diversity of models, Bayesian phylogenetics allows evolutionary biologists, systematists, ecologists, and epidemiologists to obtain answers to very detailed phylogenetic questions. Suitable for graduate-level researchers in statistics and biology, Bayesian Phylogenetics: Methods, Algorithms, and Applications presents a snapshot of current trends in Bayesian phylogenetic research. Encouraging interdisciplinary research, this book introduces state-of-the-art phylogenetics to the Bayesian statistical community and, likewise, presents state-of-the-art Bayesian statistics to the phylogenetics community. The book emphasizes model selection, reflecting recent interest in accurately estimating marginal likelihoods. It also discusses new approaches to improve mixing in Bayesian phylogenetic analyses in which the tree topology varies. In addition, the book covers divergence time estimation, biologically realistic models, and the burgeoning interface between phylogenetics and population genetics.