Time Course And Transmitter Release At The Frog Neuromuscular Junction

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Pharmacology of Neurotransmitter Release

Author : Thomas C. Südhof
Publisher : Springer Science & Business Media
ISBN 13 : 3540748059
Total Pages : 582 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Pharmacology of Neurotransmitter Release by : Thomas C. Südhof

Download or read book Pharmacology of Neurotransmitter Release written by Thomas C. Südhof and published by Springer Science & Business Media. This book was released on 2007-12-07 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been known for half a century that neurotransmitters are released in preformed quanta, that the quanta represent transmitter-storing vesicles, and that release occurs by exocytosis. The focus of this book is twofold. In the first part, the molecular events of exocytosis are analysed. In the second part of the book, the presynaptic receptors for endogenous chemical signals are presented that make neurotransmitter release a highly regulated process.

Anesthetic Pharmacology

Author : Alex S. Evers
Publisher : Cambridge University Press
ISBN 13 : 1139497022
Total Pages : 2902 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Anesthetic Pharmacology by : Alex S. Evers

Download or read book Anesthetic Pharmacology written by Alex S. Evers and published by Cambridge University Press. This book was released on 2011-03-10 with total page 2902 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Basic Neurochemistry

Author : R. Wayne Albers
Publisher : Academic Press
ISBN 13 : 0080959016
Total Pages : 1121 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Basic Neurochemistry by : R. Wayne Albers

Download or read book Basic Neurochemistry written by R. Wayne Albers and published by Academic Press. This book was released on 2011-11-02 with total page 1121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Neurochemistry, Eighth Edition, is the updated version of the outstanding and comprehensive classic text on neurochemistry. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from intracellular trafficking, stem cells, adult neurogenesis, regeneration, and lipid messengers. It contains expanded coverage of all major neurodegenerative and psychiatric disorders, including the neurochemistry of addiction, pain, and hearing and balance; the neurobiology of learning and memory; sleep; myelin structure, development, and disease; autism; and neuroimmunology. - Completely updated text with new authors and material, and many entirely new chapters - Over 400 fully revised figures in splendid color - 61 chapters covering the range of cellular, molecular and medical neuroscience - Translational science boxes emphasizing the connections between basic and clinical neuroscience - Companion website at http://elsevierdirect.com/companions/9780123749475

Basic Neurochemistry

Author : George J. Siegel
Publisher : Lippincott Raven
ISBN 13 :
Total Pages : 1216 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Basic Neurochemistry by : George J. Siegel

Download or read book Basic Neurochemistry written by George J. Siegel and published by Lippincott Raven. This book was released on 1999 with total page 1216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Illustrations by Lorie M. Gavulic, MFA Sponsored by the American Society for Neurochemistry.

Electrodiagnosis in Diseases of Nerve and Muscle

Author : Jun Kimura
Publisher : Oxford University Press
ISBN 13 : 0199738688
Total Pages : 1177 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Electrodiagnosis in Diseases of Nerve and Muscle by : Jun Kimura

Download or read book Electrodiagnosis in Diseases of Nerve and Muscle written by Jun Kimura and published by Oxford University Press. This book was released on 2013-10 with total page 1177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for clinicians who perform electrodiagnostic procedures as an extension of their clinical examination, and for neurologists and physiatrists who are interested in neuromuscular disorders and noninvasive electrodiagnostic methods, particularly those practicing electromyography (EMG) this book provides a comprehensive review of most peripheral nerve and muscle diseases, including specific techniques and locations for performing each test.

Neurotransmitter Release

Author : Hugo J. Bellen
Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 466 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Neurotransmitter Release by : Hugo J. Bellen

Download or read book Neurotransmitter Release written by Hugo J. Bellen and published by Oxford University Press, USA. This book was released on 1999 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with background information on neurotransmitter release. Emphasis is placed on the rationale by which proteins are assigned specific functions rather than just providing facts about function.

Fatigue

Author : Patricia A. Pierce
Publisher : Springer Science & Business Media
ISBN 13 : 1489910166
Total Pages : 540 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Fatigue by : Patricia A. Pierce

Download or read book Fatigue written by Patricia A. Pierce and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes the current state of our knowledge on the neurobiology of muscle fatigue, with consideration also given to selected integrative cardiorespiratory mechanisms. Our charge to the authors of the various chapters was twofold: to provide a systematic review of the topic that could serve as a balanced reference text for practicing health-care professionals, teaching faculty, and pre-and postdoctoral trainees in the biomedi cal sciences; and to stimulate further experimental and theoretical work on neurobiology. Key issues are addressed in nine interrelated areas: fatigue of single muscle fibers, fatigue at the neuromuscular junction, fatigue of single motor units, metabolic fatigue studied with nuclear magnetic resonance, fatigue of the segmental motor system, fatigue involving suprasegmental mechanisms, the task dependency of fatigue mechanisms, integrative (largely cardiorespiratory) systems issues, and fatigue of adapted systems (due to aging, under-and overuse, and pathophysiology). The product is a volume that provides compre of processes that operate from the forebrain to the contractile proteins.

Calcium, Neuronal Function and Transmitter Release

Author : Rami Rahamimoff
Publisher : Springer Science & Business Media
ISBN 13 : 146132307X
Total Pages : 617 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Calcium, Neuronal Function and Transmitter Release by : Rami Rahamimoff

Download or read book Calcium, Neuronal Function and Transmitter Release written by Rami Rahamimoff and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: This symposium entitled Calcium, Neuronal Function and Transmitter Re lease, was in the framework of the regional meeting of the International Union of Physiological Sciences, that took place in Jerusalem between August 26-31, 1984. The symposium dealt with the role of calcium ions in regulation of a large number of important processes in modern neurobiology, from molecular and cellular points of view. In this context, we consider heart and most cells as 'honorary neurons'. The meeting was comprised of lectures and quite intense discussions. We hope that the transcription of the discussions which follow the articles will give the reader a feeling of the intense, but pleasant atmosphere that per vaded during this symposium. It is our pleasure to thank Mrs. Miriam Silber, the assistant editor of this book, for her hard work in transcribing the discussions, retyping large portions of the book, and getting the approval of the authors. We express our thanks to Dr. Halina Meiri and Dr. Simona Ginsburg for their editorial assis tance. The unfailing help of Ms. Rachel Klein and Ms. Shoshana Wineberg is greatly appreciated. xxvii SECTION 1 CALCIUM CHANNELS, TRANSPORTERS & CALCIUM REGULATED CHANNELS EFFECTS OF TEMPERATURE ON SINGLE CHANNEL AND WHOLE CELL Ca CURRENTS A. M. BROWN, D. L. KUNZE, H.D. LUX AND D. L. WILSON INTRODUCTION Calcium tall currents have a large,fast component which Is not detectable when the currents are turned on or acti vated from the completely rested state (Brown et aI, 1983).

The Squid Giant Synapse

Author : Rodolfo Riascos Llinás
Publisher :
ISBN 13 : 9780195116526
Total Pages : 234 pages
Book Rating : 4.1/5 (165 download)

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Book Synopsis The Squid Giant Synapse by : Rodolfo Riascos Llinás

Download or read book The Squid Giant Synapse written by Rodolfo Riascos Llinás and published by . This book was released on 1999 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: The squid giant synapse is the single most important model for investigating the transmitter release mechanism in chemical junctions. This unique book, by a leading expert in the field, gives a concise overview of all that has been learned about synaptic transmission in this superb model system. It covers in detail the biophysics of the voltage-dependent calcium currents, calcium concentration microdomains, and much of the molecular basis for the triggering of the secretory event. Ideal for graduate and undergraduate courses, the book includes PC and Macintosh versions of two programs for simulating and manipulating any aspect of synaptic transmission. One program is a modeling tool designed for working neuroscientists, and the other teaches the basic principles of synaptic transmission by allowing students to alter the parameters, essentially without limits, and see the effects on the action potential over time. Anyone studying this central topic of neuroscience will find this book an invaluable resource.

Neuromuscular Junction

Author : R.E.M. Bowden
Publisher : Springer Science & Business Media
ISBN 13 : 3642454763
Total Pages : 758 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Neuromuscular Junction by : R.E.M. Bowden

Download or read book Neuromuscular Junction written by R.E.M. Bowden and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: Has the neuromuscular junction been over-exposed or is it perhaps already a closed book? I asked myself this at a recent International Congress when an American colleague complained that the Journal of Physiology had articles on nothing but the neuromuscular junction, while another colleague asked why I was editing a volume on a subject about which everything was already known. It is worrying to think that these views may be shared by other people. I hope that this volume will convince my two colleagues and other readers that the neuromuscular junction is very much alive and continues to attract the interest of many workers from a variety of fields; strange as it may seem, the synapse between a motor nerve ending and muscle fibre, with its relatively simple architecture, is one of the most inter esting sites in the body-I do hope we have done it justice. The various chapters of this volume present a cross section of knowledge as viewed by a group of 13 individuals, actively engaged in research. Multi-author volumes such as this are frequently criticised on the grounds that chapters or sec tions overlap. I believe that such criticium is only valid where the overlap is repetitious. Where it results in the reader having available discussions of material from differing stand-points, overlap becomes a valuable feature of this type of publication.

Neurotransmitter Release and Its Modulation

Author : David A. Powis
Publisher : Cambridge University Press
ISBN 13 : 9780521446167
Total Pages : 382 pages
Book Rating : 4.4/5 (461 download)

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Book Synopsis Neurotransmitter Release and Its Modulation by : David A. Powis

Download or read book Neurotransmitter Release and Its Modulation written by David A. Powis and published by Cambridge University Press. This book was released on 1995-08-24 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: A uniquely comprehensive and integrated account of neurotransmitter modulation. Suitable for neuroscientists and non-specialists alike.

Frog Neurobiology

Author : R. Llinas
Publisher : Springer Science & Business Media
ISBN 13 : 3642663168
Total Pages : 1056 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Frog Neurobiology by : R. Llinas

Download or read book Frog Neurobiology written by R. Llinas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1056 pages. Available in PDF, EPUB and Kindle. Book excerpt: In review, the amount of information available on the morphological and func tional properties of the frog nervous system is very extensive indeed and in certain areas is the only available source of information in vertebrates. Further more, much of the now classical knowledge in neurobiology was originally ob tained and elaborated in depth in this vertebrate. To cite only a few examples, studies of nerve conduction, neuromuscular transmission, neuronal integration, sense organs, development, and locomotion have been developed with great detail in the frog and in conjunction provide the most complete holistic descrip tion of any nervous system. Added to the above considerations, the ease with which these animals may be maintained (both as adults and during development) and the advantage of their lower cost as compared with other vertebrate forms make the frog one of the most important laboratory animals in neurobiology. With these thoughts in mind, we decided to compile this volume. Our goal in doing so was to assemble as much as possible of the information available on frog neurobiology and to have the different topics covered by authorities in each of the fields represented. To keep the handbook restricted to one volume, we found it necessary to omit the large field of amphibian muscle neurobiology, which has already been summarized in various other publications.

International Review of Neurobiology

Author :
Publisher : Academic Press
ISBN 13 : 0080857620
Total Pages : 433 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis International Review of Neurobiology by :

Download or read book International Review of Neurobiology written by and published by Academic Press. This book was released on 1986-12-17 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: International Review of Neurobiology

The Laboratory Computer

Author : John Dempster
Publisher : Academic Press
ISBN 13 : 9780122095511
Total Pages : 372 pages
Book Rating : 4.0/5 (955 download)

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Book Synopsis The Laboratory Computer by : John Dempster

Download or read book The Laboratory Computer written by John Dempster and published by Academic Press. This book was released on 2001-07-10 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Laboratory Computer: A Practical Guide for Physiologists and Neuroscientists introduces the reader to both the basic principles and the actual practice of recording physiological signals using the computer. It describes the basic operation of the computer, the types of transducers used to measure physical quantities such as temperature and pressure, how these signals are amplified and converted into digital form, and the mathematical analysis techniques that can then be applied. It is aimed at the physiologist or neuroscientist using modern computer data acquisition systems in the laboratory, providing both an understanding of how such systems work and a guide to their purchase and implementation. The key facts and concepts that are vital for the effective use of computer data acquisition systems A unique overview of the commonly available laboratory hardware and software, including both commercial and free software A practical guide to designing one's own or choosing commercial data acquisition hardware and software

Intercellular Communication in the Nervous System

Author : Robert Malenka
Publisher : Academic Press
ISBN 13 : 0123785723
Total Pages : 777 pages
Book Rating : 4.1/5 (237 download)

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Book Synopsis Intercellular Communication in the Nervous System by : Robert Malenka

Download or read book Intercellular Communication in the Nervous System written by Robert Malenka and published by Academic Press. This book was released on 2010-05-22 with total page 777 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intercellular communication is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their environment is the basis of growth and development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, diabetes, and neurological and psychiatric disorders. There is substantial drug development concentrating on this and intercellular communication is the basis of much of neuropharmacology. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be yielded. Neurotransmitters/receptors, synaptic structure and organization, gap junctions, neurotrophic factors and neuropeptides are all explored in this volume, as are the ways in which signaling controls neuroendocrinology, neuroimmunology and neuropharmacology. Intercellular Communication in the Nervous System provides a valuable desk reference for all scientists who consider signaling. - Chapters offer impressive scope with topics addressing neurotransmitters/receptors, synaptic structure and organization, neuropeptides, gap junctions, neuropharmacology and more - Richly illustrated in full color with over 200 figures - Contributors represent the most outstanding scholarship in the field, with each chapter providing fully vetted and reliable expert knowledge

Encyclopedia of Neuroscience, Volume 1

Author : Larry R. Squire
Publisher : Academic Press
ISBN 13 : 0080963935
Total Pages : 12505 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Encyclopedia of Neuroscience, Volume 1 by : Larry R. Squire

Download or read book Encyclopedia of Neuroscience, Volume 1 written by Larry R. Squire and published by Academic Press. This book was released on 2009-06-12 with total page 12505 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Encyclopedia of the Neuroscience explores all areas of the discipline in its focused entries on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. Each article is written by an expert in that specific domain and peer reviewed by the advisory board before acceptance into the encyclopedia. Each article contains a glossary, introduction, a reference section, and cross-references to other related encyclopedia articles. Written at a level suitable for university undergraduates, the breadth and depth of coverage will appeal beyond undergraduates to professionals and academics in related fields.

The Fly Neuromuscular Junction: Structure and Function

Author : Vivian Budnik
Publisher : Elsevier
ISBN 13 : 0080469132
Total Pages : 421 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis The Fly Neuromuscular Junction: Structure and Function by : Vivian Budnik

Download or read book The Fly Neuromuscular Junction: Structure and Function written by Vivian Budnik and published by Elsevier. This book was released on 2006-11-02 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Drosophila larval neuromuscular junction (NMJ) has become one of the most powerful model systems to ask key neurobiological questions. This synapse is unparalleled by its accessibility, its simplicity, and the ability to manipulate genes important for synapse development and function. Its synapses have properties shared by many organisms including humans. The vast majority of genes that when mutated cause congenital disorders of the nervous system in humans, are present in the fruit fly genome, and fly models of human disorders are available. Thus, this preparation is a powerful tool to understand the normal function of these genes. This book reviews outstanding work by recognized leaders in the fields of Drosophila cellular neurogenetics including developmental neurobiology, mechanisms of synaptic function, and experience dependent changes at synapses. The book also includes step-by-step protocols to study the cellular biology of the NMJ, making it a vital resource for researchers beginning their investigations with this system, for those who are training students and postdoctoral fellows in this area, or simply as a general reference material for neuroscientists and neuroscience professors in general.* Provides a synthesis of the main topics in modern neurogenetics* Includes step-by-step protocols for the use of the Drosophila NMJ system in neurobiology lab research* Offers genetic approaches to study synapse development and function*