Thermodynamics Of Pharmaceutical Systems

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Thermodynamics of Pharmaceutical Systems

Author : Kenneth A. Connors
Publisher : John Wiley & Sons
ISBN 13 : 0470567511
Total Pages : 379 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Thermodynamics of Pharmaceutical Systems by : Kenneth A. Connors

Download or read book Thermodynamics of Pharmaceutical Systems written by Kenneth A. Connors and published by John Wiley & Sons. This book was released on 2010-01-22 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed for pharmacy students Now updated for its Second Edition, Thermodynamics of Pharmaceutical Systems provides pharmacy students with a much-needed introduction to the mathematical intricacies of thermodynamics in relation to practical laboratory applications. Designed to meet the needs of the contemporary curriculum in pharmacy schools, the text makes these connections clear, emphasizing specific applications to pharmaceutical systems including dosage forms and newer drug delivery systems. Students and practitioners involved in drug discovery, drug delivery, and drug action will benefit from Connors' and Mecozzi's authoritative treatment of the fundamentals of thermodynamics as well as their attention to drug molecules and experimental considerations. They will appreciate, as well, the significant revisions to the Second Edition. Expanding the book's scope and usefulness, the new edition: Explores in greater depth topics most relevant to the pharmacist such as drug discovery and drug delivery, supramolecular chemistry, molecular recognition, and nanotechnologies Moves the popular review of mathematics, formerly an appendix, to the front of the book Adds new textual material and figures in several places, most notably in the chapter treating noncovalent chemical interactions Two new appendices provide ancillary material that expands on certain matters bordering the subject of classical thermodynamics Thermodynamics need not be a mystery nor confined to the realm of mathematical theory. Thermodynamics of Pharmaceutical Systems, Second Edition demystifies for students the profound thermodynamic applications in the laboratory while also serving as a handy resource for practicing researchers.

Thermodynamics of Pharmaceutical Systems

Author : Kenneth A. Connors
Publisher : John Wiley & Sons
ISBN 13 : 0471461393
Total Pages : 358 pages
Book Rating : 4.4/5 (714 download)

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Book Synopsis Thermodynamics of Pharmaceutical Systems by : Kenneth A. Connors

Download or read book Thermodynamics of Pharmaceutical Systems written by Kenneth A. Connors and published by John Wiley & Sons. This book was released on 2003-04-02 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies of thermodynamics often fail to demonstrate how the mathematical intricacies of the subject relate to practical laboratory applications. Thermodynamics of Pharmaceutical Systems makes these connections clear, emphasizing specific applications to pharmaceutical systems in a study created specifically for contemporary curriculums at colleges of pharmacy. Students investigating drug discovery, drug delivery, and drug action will benefit from Kenneth Connors's authoritative treatment of the fundamentals of thermodynamics as well as his attention to drug molecules and experimental considerations. An extensive appendix that reviews the mathematics needed to master the pharmacy curriculum proves an invaluable reference. Connors divides his one-of-a-kind text into three sections: Basic Thermodynamics, Thermodynamics of Physical Processes, and Thermodynamics of Chemical Processes; chapters include: * Energy and the First Law of Thermodynamics * The Entropy Concept * Phase Transformations * Solubility * Acid-Base Equilibria * Noncovalent Binding Equilibria Thermodynamics need not be a mystery nor be confined to the realm of mathematical theory. Thermodynamics of Pharmaceutical Systems introduces students of pharmacy to the profound thermodynamic applications in the laboratory while also serving as a handy resource for practicing researchers.

Chemical Engineering in the Pharmaceutical Industry

Author : Mary T. am Ende
Publisher : John Wiley & Sons
ISBN 13 : 111928550X
Total Pages : 1435 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Chemical Engineering in the Pharmaceutical Industry by : Mary T. am Ende

Download or read book Chemical Engineering in the Pharmaceutical Industry written by Mary T. am Ende and published by John Wiley & Sons. This book was released on 2019-04-08 with total page 1435 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products.

Drug-Receptor Thermodynamics

Author : Robert B. Raffa
Publisher : Wiley
ISBN 13 : 9780471720423
Total Pages : 0 pages
Book Rating : 4.7/5 (24 download)

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Book Synopsis Drug-Receptor Thermodynamics by : Robert B. Raffa

Download or read book Drug-Receptor Thermodynamics written by Robert B. Raffa and published by Wiley. This book was released on 2001-06-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug-Receptor Thermodynamics is the first book to provide in depth coverage of principles and applications of thermodynamic drug-receptor interactions. The book starts from familiar points, making thermodynamics accessible to anyone interested in how drugs work. The ideas presented cover general principles as well as laying the groundwork for new ways of examining drug action. * covers an area of increasing interest and relevance in the field of drug design and discovery * excellent explanation of why thermodynamics is at the heart of drug action * contributions from many of the worlds leading experts in the field Anyone interested in drug receptor interaction will find something of use in this book. It will be of particular relevance for pharmacologists, health science researchers and medicinal chemists.

Chemical Thermodynamics for Industry

Author : Trevor M Letcher
Publisher : Royal Society of Chemistry
ISBN 13 : 184755041X
Total Pages : 294 pages
Book Rating : 4.8/5 (475 download)

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Book Synopsis Chemical Thermodynamics for Industry by : Trevor M Letcher

Download or read book Chemical Thermodynamics for Industry written by Trevor M Letcher and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Thermodynamics for Industry presents the latest developments in applied thermodynamics and highlights the role of thermodynamics in the chemical industry. Written by leading experts in the field, Chemical Thermodynamics for Industry covers the latest developments in traditional areas such as calorimetry, microcalorimetry, transport properties, crystallization, adsorption, electrolyte systems and transport fuels, It highlights newly established areas such as multiphase modeling, reactive distillation, non-equilibrium thermodynamics and spectro-calorimetry. It also explores new ways of treating old technologies as well as new and potentially important areas such as ionic liquids, new materials, ab-initia quantum chemistry, nano-particles, polymer recycling, clathrates and the economic value of applied thermodynamics. This book is aimed not only at those working in a specific area of chemical thermodynamics but also at the general chemist, the prospective researcher and those involved in funding chemical research.

Pharmaceutical Amorphous Solid Dispersions

Author : Ann Newman
Publisher : John Wiley & Sons
ISBN 13 : 1118455207
Total Pages : 502 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis Pharmaceutical Amorphous Solid Dispersions by : Ann Newman

Download or read book Pharmaceutical Amorphous Solid Dispersions written by Ann Newman and published by John Wiley & Sons. This book was released on 2015-03-09 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a roadmap from early to late stages of drug development, this book overviews amorphous solid dispersion technology – a leading platform to deliver poorly water soluble drugs, a major hurdle in today’s pharmaceutical industry. • Helps readers understand amorphous solid dispersions and apply techniques to particular pharmaceutical systems • Covers physical and chemical properties, screening, scale-up, formulation, drug product manufacture, intellectual property, and regulatory considerations • Has an appendix with structure and property information for polymers commonly used in drug development and with marketed drugs developed using the amorphous sold dispersion approach • Addresses global regulatory issues including USA regulations, ICH guidelines, and patent concerns around the world

Chemical Engineering in the Pharmaceutical Industry

Author : David J. am Ende
Publisher : John Wiley & Sons
ISBN 13 : 1118088107
Total Pages : 1431 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Chemical Engineering in the Pharmaceutical Industry by : David J. am Ende

Download or read book Chemical Engineering in the Pharmaceutical Industry written by David J. am Ende and published by John Wiley & Sons. This book was released on 2011-03-10 with total page 1431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with various unique elements in the drug development process within chemical engineering science and pharmaceutical R&D. The book is intended to be used as a professional reference and potentially as a text book reference in pharmaceutical engineering and pharmaceutical sciences. Many of the experimental methods related to pharmaceutical process development are learned on the job. This book is intended to provide many of those important concepts that R&D Engineers and manufacturing Engineers should know and be familiar if they are going to be successful in the Pharmaceutical Industry. These include basic analytics for quantitation of reaction components– often skipped in ChE Reaction Engineering and kinetics books. In addition Chemical Engineering in the Pharmaceutical Industry introduces contemporary methods of data analysis for kinetic modeling and extends these concepts into Quality by Design strategies for regulatory filings. For the current professionals, in-silico process modeling tools that streamline experimental screening approaches is also new and presented here. Continuous flow processing, although mainstream for ChE, is unique in this context given the range of scales and the complex economics associated with transforming existing batch-plant capacity. The book will be split into four distinct yet related parts. These parts will address the fundamentals of analytical techniques for engineers, thermodynamic modeling, and finally provides an appendix with common engineering tools and examples of their applications.

Polymorphism in the Pharmaceutical Industry

Author : Rolf Hilfiker
Publisher : John Wiley & Sons
ISBN 13 : 3527697853
Total Pages : 618 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Polymorphism in the Pharmaceutical Industry by : Rolf Hilfiker

Download or read book Polymorphism in the Pharmaceutical Industry written by Rolf Hilfiker and published by John Wiley & Sons. This book was released on 2019-01-04 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Polymorphism in the Pharmaceutical Industry - Solid Form and Drug Development" highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus on quality by design (QbD) concepts. It covers all important issues by way of case studies, ranging from properties and crystallization, via thermodynamics, analytics and theoretical modelling right up to patent issues. As such, the book underscores the importance of solid-state chemistry within chemical and pharmaceutical development. It emphasizes why solid-state issues are important, the approaches needed to avoid problems and the opportunities offered by solid-state properties. The authors include true polymorphs as well as solvates and hydrates, while providing information on physicochemical properties, crystallization thermodynamics, quantum-mechanical modelling, and up-scaling. Important analytical tools to characterize solid-state forms and to quantify mixtures are summarized, and case studies on solid-state development processes in industry are also provided. Written by acknowledged experts in the field, this is a high-quality reference for researchers, project managers and quality assurance managers in pharmaceutical, agrochemical and fine chemical companies as well as for academics and newcomers to organic solid-state chemistry.

Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics

Author : Patrick Augustijns
Publisher : Springer Science & Business Media
ISBN 13 : 0387691545
Total Pages : 462 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics by : Patrick Augustijns

Download or read book Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics written by Patrick Augustijns and published by Springer Science & Business Media. This book was released on 2007-08-06 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solvent systems are integral to drug development and pharmaceutical technology. This single topic encompasses numerous allied subjects running the gamut from recrystallization solvents to biorelevant media. The goal of this contribution to the AAPS Biotechnology: Pharmaceutical Aspects series is to generate both a practical handbook as well as a reference allowing the reader to make effective decisions concerning the use of solvents and solvent systems. To this end, the monograph was created by inviting recognized experts from a number of fields to author relevant sections. Specifically, 15 chapters have been designed covering the theoretical background of solubility, the effect of ionic equilibria and pH on solubilization, the use of solvents to effect drug substance crystallization and polymorph selection, the use of solvent systems in high throughput screening and early discovery, solvent use in preformulation, the use of solvents in bio-relevant dissolution and permeation experiments, solvents and their use as toxicology vehicles, solubilizing media and excipients in oral and parenteral formulation development, specialized vehicles for protein formulation and solvent systems for topical and pulmonary drug administration. The chapters are organized such that useful decision trees are included together with the scientific underpinning for their application. In addition, trends in the use of solvent systems and a balance of current views make this monograph useful to both the novice and experienced researcher and to scientists at all developmental stages from early discovery to late pharmaceutical operations.

Lectures in Classical Thermodynamics with an Introduction to Statistical Mechanics

Author : Daniel Blankschtein
Publisher : Springer Nature
ISBN 13 : 3030491986
Total Pages : 758 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Lectures in Classical Thermodynamics with an Introduction to Statistical Mechanics by : Daniel Blankschtein

Download or read book Lectures in Classical Thermodynamics with an Introduction to Statistical Mechanics written by Daniel Blankschtein and published by Springer Nature. This book was released on 2021-03-15 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook facilitates students’ ability to apply fundamental principles and concepts in classical thermodynamics to solve challenging problems relevant to industry and everyday life. It also introduces the reader to the fundamentals of statistical mechanics, including understanding how the microscopic properties of atoms and molecules, and their associated intermolecular interactions, can be accounted for to calculate various average properties of macroscopic systems. The author emphasizes application of the fundamental principles outlined above to the calculation of a variety of thermodynamic properties, to the estimation of conversion efficiencies for work production by heat interactions, and to the solution of practical thermodynamic problems related to the behavior of non-ideal pure fluids and fluid mixtures, including phase equilibria and chemical reaction equilibria. The book contains detailed solutions to many challenging sample problems in classical thermodynamics and statistical mechanics that will help the reader crystallize the material taught. Class-tested and perfected over 30 years of use by nine-time Best Teaching Award recipient Professor Daniel Blankschtein of the Department of Chemical Engineering at MIT, the book is ideal for students of Chemical and Mechanical Engineering, Chemistry, and Materials Science, who will benefit greatly from in-depth discussions and pedagogical explanations of key concepts. Distills critical concepts, methods, and applications from leading full-length textbooks, along with the author’s own deep understanding of the material taught, into a concise yet rigorous graduate and advanced undergraduate text; Enriches the standard curriculum with succinct, problem-based learning strategies derived from the content of 50 lectures given over the years in the Department of Chemical Engineering at MIT; Reinforces concepts covered with detailed solutions to illuminating and challenging homework problems.

Nonequilibrium Thermodynamics

Author : Yasar Demirel
Publisher : Newnes
ISBN 13 : 0444595813
Total Pages : 792 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Nonequilibrium Thermodynamics by : Yasar Demirel

Download or read book Nonequilibrium Thermodynamics written by Yasar Demirel and published by Newnes. This book was released on 2013-12-16 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural phenomena consist of simultaneously occurring transport processes and chemical reactions. These processes may interact with each other and may lead to self-organized structures, fluctuations, instabilities, and evolutionary systems. Nonequilibrium Thermodynamics, Third Edition emphasizes the unifying role of thermodynamics in analyzing the natural phenomena. This third edition updates and expands on the first and second editions by focusing on the general balance equations for coupled processes of physical, chemical, and biological systems. The new edition contains a new chapter on stochastic approaches to include the statistical thermodynamics, mesoscopic nonequilibrium thermodynamics, fluctuation theory, information theory, and modeling the coupled biochemical systems in thermodynamic analysis. This new addition also comes with more examples and practice problems. Informs and updates on all the latest developments in the field Contributions from leading authorities and industry experts A useful text for seniors and graduate students from diverse engineering and science programs to analyze some nonequilibrium, coupled, evolutionary, stochastic, and dissipative processes Highlights fundamentals of equilibrium thermodynamics, transport processes and chemical reactions Expands the theory of nonequilibrium thermodynamics and its use in coupled transport processes and chemical reactions in physical, chemical, and biological systems Presents a unified analysis for transport and rate processes in various time and space scales Discusses stochastic approaches in thermodynamic analysis including fluctuation and information theories Has 198 fully solved examples and 287 practice problems An Instructor Resource containing the Solution Manual can be obtained from the author: [email protected]

Thermodynamics of Solutions

Author : Eli Ruckenstein
Publisher : Springer Science & Business Media
ISBN 13 : 1441904409
Total Pages : 349 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Thermodynamics of Solutions by : Eli Ruckenstein

Download or read book Thermodynamics of Solutions written by Eli Ruckenstein and published by Springer Science & Business Media. This book was released on 2009-06-17 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book consists of a number of papers regarding the thermodynamics and structure of multicomponent systems that we have published during the last decade. Even though they involve different topics and different systems, they have something in common which can be considered as the “signature” of the present book. First, these papers are concerned with “difficult” or very nonideal systems, i. e. systems with very strong interactions (e. g. , hyd- gen bonding) between components or systems with large differences in the partial molar v- umes of the components (e. g. , the aqueous solutions of proteins), or systems that are far from “normal” conditions (e. g. , critical or near-critical mixtures). Second, the conventional th- modynamic methods are not sufficient for the accurate treatment of these mixtures. Last but not least, these systems are of interest for the pharmaceutical, biomedical, and related ind- tries. In order to meet the thermodynamic challenges involved in these complex mixtures, we employed a variety of traditional methods but also new methods, such as the fluctuation t- ory of Kirkwood and Buff and ab initio quantum mechanical techniques. The Kirkwood-Buff (KB) theory is a rigorous formalism which is free of any of the - proximations usually used in the thermodynamic treatment of multicomponent systems. This theory appears to be very fruitful when applied to the above mentioned “difficult” systems.

Pharmaceutical Nanotechnology

Author : Costas Demetzos
Publisher : Springer
ISBN 13 : 9811007918
Total Pages : 203 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Pharmaceutical Nanotechnology by : Costas Demetzos

Download or read book Pharmaceutical Nanotechnology written by Costas Demetzos and published by Springer. This book was released on 2016-05-11 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook explains the fundamental aspects of nanotechnology and fills the gap between bio-inspired nanotechnological systems and functionality of living organisms, introducing new insights to their physicochemical, biophysical and thermodynamic behaviour. Addressed to all those involved in recent advances in pharmaceutics, this book is divided in three major parts: Part A refers to the physicochemical and thermodynamics aspects of nanosystems, wherein their biophysical behaviour is correlated with that of the cells of living organisms; Part B refers to the application of nanotechnology in imaging, diagnostics and therapeutics; Part C is focused on issues regarding safety and nanotoxicity of nanosystems, and the regulatory framework that surrounds these. The text promotes the concept that biophysics, thermodynamics and nanotechnology are considered to be emerging tools that, when approached within regulatory boundaries, provide new and integrated knowledge for the production of new medicines. In 2018, Prof. Demetzos was honored with an award by the Order of Sciences of the Academy of Athens for his scientific contribution in Pharmaceutical Nanotechnology.

Chemical Engineering in the Pharmaceutical Industry

Author : David J. am Ende
Publisher : John Wiley & Sons
ISBN 13 : 1119285860
Total Pages : 1172 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Chemical Engineering in the Pharmaceutical Industry by : David J. am Ende

Download or read book Chemical Engineering in the Pharmaceutical Industry written by David J. am Ende and published by John Wiley & Sons. This book was released on 2019-04-23 with total page 1172 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the development and manufacturing of pharmaceutical products written for professionals in the industry, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry is a practical book that highlights chemistry and chemical engineering. The book’s regulatory quality strategies target the development and manufacturing of pharmaceutically active ingredients of pharmaceutical products. The expanded second edition contains revised content with many new case studies and additional example calculations that are of interest to chemical engineers. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The active pharmaceutical ingredients book puts the focus on the chemistry, chemical engineering, and unit operations specific to development and manufacturing of the active ingredients of the pharmaceutical product. The drug substance operations section includes information on chemical reactions, mixing, distillations, extractions, crystallizations, filtration, drying, and wet and dry milling. In addition, the book includes many applications of process modeling and modern software tools that are geared toward batch-scale and continuous drug substance pharmaceutical operations. This updated second edition: Contains 30new chapters or revised chapters specific to API, covering topics including: manufacturing quality by design, computational approaches, continuous manufacturing, crystallization and final form, process safety Expanded topics of scale-up, continuous processing, applications of thermodynamics and thermodynamic modeling, filtration and drying Presents updated and expanded example calculations Includes contributions from noted experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduate students, and professionals in the field of pharmaceutical sciences and manufacturing, the second edition of Chemical Engineering in the Pharmaceutical Industryf ocuses on the development and chemical engineering as well as operations specific to the design, formulation, and manufacture of drug substance and products.

Using Aspen Plus in Thermodynamics Instruction

Author : Stanley I. Sandler
Publisher : John Wiley & Sons
ISBN 13 : 1118996917
Total Pages : 372 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Using Aspen Plus in Thermodynamics Instruction by : Stanley I. Sandler

Download or read book Using Aspen Plus in Thermodynamics Instruction written by Stanley I. Sandler and published by John Wiley & Sons. This book was released on 2015-04-06 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: A step-by-step guide for students (and faculty) on the use of Aspen in teaching thermodynamics • Easily-accessible modern computational techniques opening up new vistas in teaching thermodynamics A range of applications of Aspen Plus in the prediction and calculation of thermodynamic properties and phase behavior using the state-of-the art methods • Encourages students to develop engineering insight by doing repetitive calculations with changes in parameters and/or models • Calculations and application examples in a step-by-step manner designed for out-of-classroom self-study • Makes it possible to easily integrate Aspen Plus into thermodynamics courses without using in-class time • Stresses the application of thermodynamics to real problems

Thermodynamics of Biochemical Reactions

Author : Robert A. Alberty
Publisher : John Wiley & Sons
ISBN 13 : 0471623555
Total Pages : 409 pages
Book Rating : 4.4/5 (716 download)

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Book Synopsis Thermodynamics of Biochemical Reactions by : Robert A. Alberty

Download or read book Thermodynamics of Biochemical Reactions written by Robert A. Alberty and published by John Wiley & Sons. This book was released on 2005-01-28 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ein Lehr- und Handbuch der Thermodynamik biochemischer Reaktionen mit modernen Beispielen und umfangreichen Hinweisen auf die Originalliteratur. - Schwerpunkt liegt auf Stoffwechsel und enzymkatalysierten Reaktionen - Grundlagen der Thermodynamik (z. B. chemisches Gleichgewicht) werden anschaulich abgehandelt - zu den speziellen Themen gehören Reaktionen in Matrices, Komplexbildungsgleichgewichte und Ligandenbindung, Phasengleichgewichte, Redoxreaktionen, Kalorimetrie

Transport Processes in Pharmaceutical Systems

Author : Gordon L. Amidon
Publisher : CRC Press
ISBN 13 : 0824746325
Total Pages : 746 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Transport Processes in Pharmaceutical Systems by : Gordon L. Amidon

Download or read book Transport Processes in Pharmaceutical Systems written by Gordon L. Amidon and published by CRC Press. This book was released on 1999-11-24 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cutting-edge reference clearly explains pharmaceutical transport phenomena, demonstrating applications ranging from drug or nutrient uptake into vesicle or cell suspensions, drug dissolution and absorption across biological membranes, whole body kinetics, and drug release from polymer reservoirs and matrices to heat and mass transport in freeze-drying and hygroscopicity. Focuses on practical applications of drug delivery from a physical and mechanistic perspective, highlighting biological systems. Written by more than 30 international authorities in the field, Transport Processes in Pharmaceutical Systems discusses the crucial relationship between the transport process and thermodynamic factors analyzes the dynamics of diffusion at liquid-liquid, liquid-solid, and liquid-cultured cell interfaces covers prodrug design for improving membrane transport addresses the effects of external stimuli in altering some natural and synthetic polymer matrices examines properties of hydrogels, including synthesis, swelling degree, swelling kinetics, permeability, biocompatibility, and biodegradability presents mass transfer of drugs and pharmacokinetics based on mass balance descriptions and more! Containing over 1000 references and more than 1100 equations, drawings, photographs, micrographs, and tables, Transport Processes in Pharmaceutical Systems is a must-read resource for research pharmacists, pharmaceutical scientists and chemists, chemical engineers, physical chemists, and upper-level undergraduate and graduate students in these disciplines.