Theory And Applications Of Nonparenteral Nanomedicines

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Theory and Applications of Nonparenteral Nanomedicines

Author : Prashant Kesharwani
Publisher : Academic Press
ISBN 13 : 0128204672
Total Pages : 542 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Theory and Applications of Nonparenteral Nanomedicines by : Prashant Kesharwani

Download or read book Theory and Applications of Nonparenteral Nanomedicines written by Prashant Kesharwani and published by Academic Press. This book was released on 2020-09-12 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theory and Applications of Nonparenteral Nanomedicines presents thoroughly analysed data and results regarding the potential of nanomedicines conceived by diverse non-parenteral routes. In the context of nanotechnology-based approaches, various routes such as oral, pulmonary, transdermal, delivery and local administration of nanomedicine have been utilized for the delivery of nanomedicine. This book discusses the non-parenteral application of nanomedicine, its regulatory implications, application of mucus penetrating nanocarrier, and detailed chapters on development of nanomedicines developed for drug delivery by various route. Beginning with a brief introduction to the non-parenteral delivery of nanomedicine and the safety and regulatory implications of the nanoformulations, further chapters discuss the physiology of the biological barriers, the specificity of the nanocarriers as well as their multiple applications. Theory and Applications of Nonparenteral Nanomedicines helps clinical researchers, researchers working in pharmaceutical industries, graduate students, and anyone working in the development of non-parenteral nanomedicines to understand the recent progress in the design and development of nanoformulations compatible with non-parenteral applications. Contains a comprehensive review of non-parenteral nanomedicines Provides analysis of non-parenteral methods of nanomedicines including regulatory implications and future applications Explores a wide range of promising approaches for non-parenteral drug delivery using the latest advancement in nanomedicine written by experts in industry and academia

Emerging Nanomedicines for Diabetes Mellitus Theranostics

Author : Michael K Danquah
Publisher : Elsevier
ISBN 13 : 0323853978
Total Pages : 282 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Emerging Nanomedicines for Diabetes Mellitus Theranostics by : Michael K Danquah

Download or read book Emerging Nanomedicines for Diabetes Mellitus Theranostics written by Michael K Danquah and published by Elsevier. This book was released on 2022-04-09 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging Nanomedicines for Diabetes Mellitus Theranostics provides readers with information on the development of efficacious nanomedicines as potential theranostic agents for diabetes. The book discusses the application of various novel nanomaterials and nanocomposites for targeted delivery of insulin, glucose sensing, including nano-tattoos as glucose monitors, biosynthesized nanoparticles for diabetes treatment, and pre-clinical and clinical assays to evaluate the efficacy of nanomedicines for diabetes treatment. This is an important references source for materials scientists, pharmaceutical scientists and biomedical engineers who want to increase their understanding of how nanotechnology is being used to improve diabetes treatment. Diabetes has emerged as one of the most common diseases associated with lifestyle choices in the modern world, with significant mortality rates. Conventional treatment methods mainly involve insulin-based therapies. However, insulin therapy possesses several limitations such as weight gain and hypoglycemia. Thus, advanced research in nanomedicine is targeting the development of new and improved diagnostics and treatment methods for diabetes. Explores the significance of nanomaterials and nanocomposites for the controlled delivery of insulin and effective diagnosis of diabetes Assesses the efficacy of novel nano-tattoos as an emerging glucose monitoring system and the potential of biosynthesized nanoparticles as pharmaceutical ingredients for diabetes treatment Describes various pre-clinical and clinical assays to evaluate the toxicity of nanomedicines, along with methods to mitigate the challenges associated with effective diabetes therapy via the use of nanorobots, nanoformulations and smartphone-based technologies

Nanomaterials and Nanotechnology in Medicine

Author : Visakh P. M.
Publisher : John Wiley & Sons
ISBN 13 : 1119558034
Total Pages : 580 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Nanomaterials and Nanotechnology in Medicine by : Visakh P. M.

Download or read book Nanomaterials and Nanotechnology in Medicine written by Visakh P. M. and published by John Wiley & Sons. This book was released on 2022-09-13 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: NANOMATERIALS AND NANOTECHNOLOGY IN MEDICINE A comprehensive introduction to nanomaterials and their application in the field of medicine The use of nanotechnology and nanomaterials more generally is an emerging field that has generated a lot of interest in the last few years. To this point, there have been few books that deal with the recent advances in nanomaterials or nanocomposites in the medical discipline. Intended as a one-stop reference, Nanomaterials and Nanotechnology in Medicine provides the reader with the most-up-to-date and comprehensive exploration of the field of nanomedicine. The scope of the topic is huge, with nano applications in every medical specialization—from diagnostics to pharmaceuticals, from biological therapies to surgical devices, and from regenerative therapies to gene therapy. As such, this volume provides the most comprehensive coverage of this intriguing field of study. Nanomaterials and Nanotechnology in Medicine readers will also find: An application-oriented book dedicated towards helping researchers find solutions to both fundamental and applied problems Chapters written by leading researchers from industry, academy, government, and private research institutions across the globe Nanomaterials and Nanotechnology in Medicine is a useful reference for medical doctors, medical practitioners, post-doctoral research fellows, senior graduate students, and medical libraries.

Nanomedicine-Based Approaches for the Treatment of Dementia

Author : Umesh Gupta
Publisher : Academic Press
ISBN 13 : 0323859062
Total Pages : 320 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Nanomedicine-Based Approaches for the Treatment of Dementia by : Umesh Gupta

Download or read book Nanomedicine-Based Approaches for the Treatment of Dementia written by Umesh Gupta and published by Academic Press. This book was released on 2022-10-11 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomedicine-Based Approaches for the Treatment of Dementia explores a wide range of promising approaches for the diagnosis and treatment of dementia. The book begins with introductory sections on dementia and brain ailments that are followed by further chapters that discuss detailed information about challenges of drug delivery across the blood-brain barrier as well as the current status. This book helps readers design and develop novel drug delivery systems and devices for the treatment of dementia that take advantage of recent advances in nanomedical technologies. Numerous drug delivery systems have been developed recently for dementia. Unfortunately, most of them are ineffective since dementia is not a single disease. It is an umbrella term for several neurodegenerative conditions which alter brain functions. Due to this, there is an urgent need for innovative technologies/nano drug delivery systems to improve the targeting and delivery of therapeutic as well as diagnostic agents specifically for treating dementia. Explores promising approaches for the diagnosis and treatment of dementia Discusses advances in cutting-edge nanomedical technologies Focuses on the design, synthesis and application of nanocarriers in drug delivery

Therapeutic Nanocarriers in Cancer Treatment: Challenges and Future Perspective

Author : Neeraj Mishra
Publisher : Bentham Science Publishers
ISBN 13 : 9815080512
Total Pages : 421 pages
Book Rating : 4.8/5 (15 download)

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Book Synopsis Therapeutic Nanocarriers in Cancer Treatment: Challenges and Future Perspective by : Neeraj Mishra

Download or read book Therapeutic Nanocarriers in Cancer Treatment: Challenges and Future Perspective written by Neeraj Mishra and published by Bentham Science Publishers. This book was released on 2023-03-06 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology has revolutionized cancer diagnosis and therapy through targeted drug delivery. Advances in protein engineering and materials science have led to the development of nanocarriers (NCs), which have helped overcome the challenges faced during conventional cancer treatment. These nanocarriers serve as an efficient transport module for drugs. Nano-drug delivery has emerged as a promising technology that results in early detection and better treatment of various cancers. The approved nanoparticles currently used in cancer treatment strategies include liposomes, dendrimers, polyplexes, solid lipid nano-carriers, etc. These nanocarriers can potentially provide a quick, safe, and cost-effective method in cancer therapy and management. This book presents thirteen chapters that cover cancer nanotherapeutics for various cancers. The reference covers lung, breast, cervical, ovarian, colon, prostate, and head and neck cancers. Each chapter reviews advanced data from existing and ongoing clinical research and major regulatory considerations. A list of scientific references for further reading supplements every chapter. Readers will be able to understand recent advances and challenges faced by researchers in cancer nanomedicine. This reference book will greatly benefit undergraduate and postgraduate students, oncologists, pharmacists, and researchers involved in nanomedicine and nano-drug delivery.

Advancements in Controlled Drug Delivery Systems

Author : Verma, Shekhar
Publisher : IGI Global
ISBN 13 : 1799889092
Total Pages : 395 pages
Book Rating : 4.7/5 (998 download)

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Book Synopsis Advancements in Controlled Drug Delivery Systems by : Verma, Shekhar

Download or read book Advancements in Controlled Drug Delivery Systems written by Verma, Shekhar and published by IGI Global. This book was released on 2022-03-25 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: The many drawbacks of conventional dosage forms and delivery systems are overcome by designing and developing controlled release drug delivery systems, and pharmaceutical and other scientists have carried out extensive and intensive investigations in the field to explore their applications. A controlled-release drug formulation can improve product efficacy and extend patent protection. As controlled drug delivery systems continue to play a vital role in delivering various types of therapeutic agents in a controlled manner, researchers are only just scratching the surface of their full potential. Advancements in Controlled Drug Delivery Systems supplies information on translating the physicochemical properties of drugs into drug delivery systems, explores how drugs are administered via various routes, and discusses recent advancements in the fabrication and development of controlled drug delivery systems. It also underlines the methodology of controlled drug delivery system preparation and the significance, disadvantages, detailed classifications, and relevant examples. Covering topics such as machine learning and oral-controlled drug delivery, this book is ideal for pharmacists, healthcare professionals, researchers, academicians, research centers, health units, students, and pharmaceutical and scientific laboratories.

Stimuli-Responsive Nanocarriers

Author : Virendra Gajbhiye
Publisher : Academic Press
ISBN 13 : 0323859046
Total Pages : 485 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Stimuli-Responsive Nanocarriers by : Virendra Gajbhiye

Download or read book Stimuli-Responsive Nanocarriers written by Virendra Gajbhiye and published by Academic Press. This book was released on 2022-01-04 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stimuli-Responsive Nanocarriers: Recent Advances in Tailor-Made Therapeutics compiles dispersed knowledge into a complete and comprehensive source to help researchers understand and progress stimuli-responsive nanocarriers. The book contains recent advancements made in the field of stimuli-responsive nanocarriers with their application in controlled drug delivery against various diseases. It focuses on the design, mechanism, construction, therapeutic application and future challenges of stimuli-responsive nanocarriers which will help new researchers in designing next generation tailor-made advanced therapeutics. Finally, the book covers future aspects and challenges present in the route of development of stimuli responsive nanocarriers for disease therapeutics. Various recent advances and biomedical applications assembled in this book will guide scientists on how to design and develop novel controlled drug release systems. Provides comprehensive knowledge of basic design, mechanism and construction of nanocarrier based stimuli-responsive drug releases Explores various nanocarriers characteristically used in the development of stimuli-responsive drug release systems Envisages future opportunities, challenges and implementation of nanocarrier based stimuli-responsive drug release systems in disease therapeutics

Nanotechnology and Regenerative Medicine

Author : Maria H. Santana
Publisher : Academic Press
ISBN 13 : 0323904327
Total Pages : 615 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Nanotechnology and Regenerative Medicine by : Maria H. Santana

Download or read book Nanotechnology and Regenerative Medicine written by Maria H. Santana and published by Academic Press. This book was released on 2022-11-24 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Cell niches are present in several human body tissues as a dynamic microenvironment essential to modulate stem cells’ behavior in health, under injury, and in regenerative processes. The interplay between stem cells and their niche is necessary for sustaining tissues. The extracellular matrix (ECM) is the crucial component of the stem cell. It defines the architectural space, physical binding to the cell membrane, and interactions with the neighborhood cells and supports physical stress. Domains with nano or micrometric sizes define the surface and topology of the ECM, mediating cell interactions and macrophage recruitment to injured sites. Over the last two decades, the integration of biomedicine with other engineering and biomaterial sciences promoted the development of nanotechnology and regenerative medicine toward mimicking the specialized stem cell niches to treat diseases with less invasive and efficient therapies. Innovative approaches in nanotechnology, such as targeting the immunological system, transporting drugs across blood–brain/BBB and blood–retinal barriers/BRB, directing active moiety to specific disease location/organs, encapsulation of multiple components, and promoting signalization and pathway-specific surfaces for cell interactions and growth, are indeed promising. On the other side, developments of biomaterial scaffolds to mimic the cell niches for interactions with stem cells in vitro or in vivo have tremendous potential. The three-dimensional printing technology offers a base for a wide array of applications, for example, developing tissue constructs, mimetic organs, organoids, and organ-on-a-chip, thus avoiding the differences between animal model species and humans. Aiming closer to the natural environments, fresh autologous products from the blood, such as platelet-rich plasma (PRP), contain platelets and leukocytes, providing growth factors, cytokines, and proteins for the resident stem cells in the stages of regeneration. PRP also provides pain relief, reducing disabilities in elderly or diseased people. This book brings thought-provoking multidisciplinary topics on the diverse aspects of basic and applied sciences. The prime focus of the compilation is to understand the challenges researchers encounter in combining nanotechnology and regenerative medicine, ultimately integrating both disciplines for the benefit of the patient and offering them a ray of hope to be cured. Presents multi-disciplined knowledge on bench-to-bedside application of nanotechnology in regenerative medicines Highlights the fundamentals, frontiers, limitations, and challenges faced by regenerative medicines Exhibits synergy of biotechnology, nanomedicine, biomedicine, chemical-material engineering, pharmaceutical technology, and applied medical sciences in success of regenerative medicines

Biosystems, Biomedical & Drug Delivery Systems

Author : Shrikaant Kulkarni
Publisher : Springer Nature
ISBN 13 : 9819725968
Total Pages : 376 pages
Book Rating : 4.8/5 (197 download)

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Book Synopsis Biosystems, Biomedical & Drug Delivery Systems by : Shrikaant Kulkarni

Download or read book Biosystems, Biomedical & Drug Delivery Systems written by Shrikaant Kulkarni and published by Springer Nature. This book was released on with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nanopharmacology and Nanotoxicology: Clinical Implications and Methods

Author : Elham Ahmadian
Publisher : Bentham Science Publishers
ISBN 13 : 9815079700
Total Pages : 288 pages
Book Rating : 4.8/5 (15 download)

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Book Synopsis Nanopharmacology and Nanotoxicology: Clinical Implications and Methods by : Elham Ahmadian

Download or read book Nanopharmacology and Nanotoxicology: Clinical Implications and Methods written by Elham Ahmadian and published by Bentham Science Publishers. This book was released on 2023-05-31 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains key concepts and applications of nanotechnology in clinical medicine and pharmacology. The chapters have been contributed by experts and provide a broad perspective about the current and future developments in pharmacology, toxicology, cell biology, and materials science. The book is divided into 2 main sections. The first section concerns nanobiotechnology for human health including gastrointestinal disease, kidney diseases, pulmonary disorders, reproductive system, COVID-19, and cancer. The second section is devoted to toxicological aspects of nanomaterials which involve toxicological assessments of nanotherapeutics and potential solutions for nanotoxicology. Key Features - Emphasizes the high degree of interdisciplinary research in pharmacology, toxicology and nanoscience - Summarizes the results of theoretical, methodological, and practical studies in different medical subspecialties - includes special topics such as novel nanotoxicology assessment methods and nano vaccines - Includes references for further reading

Aptamers Engineered Nanocarriers for Cancer Therapy

Author : Prashant Kesharwani
Publisher : Woodhead Publishing
ISBN 13 : 0323855768
Total Pages : 558 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Aptamers Engineered Nanocarriers for Cancer Therapy by : Prashant Kesharwani

Download or read book Aptamers Engineered Nanocarriers for Cancer Therapy written by Prashant Kesharwani and published by Woodhead Publishing. This book was released on 2022-09-25 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aptamers Engineered Nanocarriers for Cancer Therapy details the selection technologies, biological characteristics, and clinical uses of aptamer-based nano agents for cancer therapeutics. The book helps facilitate speedy solutions for some of the problems pertaining to the manufacture of nano-aptamers – such as toxicity, thermal stability, cost efficiency, tumor penetration and blood stability. Key chapters cover cell-SELEX technology for aptamer selection, mechanisms of multi-drug resistance of cancer, the relevance of aptamers as anticancer therapies, as well as the broad range of aptamer-functionalized nanostructures available. This book provides exciting insights into this relatively new approach to cancer therapeutics, and will be of interest to materials scientists, biomedical engineers, molecular biologists, biochemists and clinical scientists, with a focus on cancer therapy. Reviews the mechanisms behind multi-drug resistance (MDR) in cancer and how aptamer-mediated novel therapeutic agents and strategies can facilitate MDR reversal Covers a range of aptamers engineered nanostructures, including PLGA nanoparticles, silica nanoparticles, quantum dots, nucleic acid aptamers, and more Discusses the challenges associated with using aptamers as cancer therapeutics and how this translates into clinical use

MEMS and Microfluidics in Healthcare

Author : Koushik Guha
Publisher : Springer Nature
ISBN 13 : 9811987149
Total Pages : 251 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis MEMS and Microfluidics in Healthcare by : Koushik Guha

Download or read book MEMS and Microfluidics in Healthcare written by Koushik Guha and published by Springer Nature. This book was released on 2023-03-13 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book introduces the research significance of biomedical instrumentation and discusses micro-fabrication techniques utilized for biomedical devices. This book primarily focuses on the reader enlightenment on MEMS medical devices by introducing all the diagnostic devices and treatment tools at one place. The book covers in-depth technical works and general introductions to the devices such that the book can reach technical as well as non-technical readers.

Handbook of Bioplastics and Biocomposites Engineering Applications

Author : Inamuddin
Publisher : John Wiley & Sons
ISBN 13 : 1119160154
Total Pages : 692 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Handbook of Bioplastics and Biocomposites Engineering Applications by : Inamuddin

Download or read book Handbook of Bioplastics and Biocomposites Engineering Applications written by Inamuddin and published by John Wiley & Sons. This book was released on 2022-11-21 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Bioplastics and Biocomposites Engineering Applications The 2nd edition of this successful Handbook explores the extensive and growing applications made with bioplastics and biocomposites for the packaging, automotive, biomedical, and construction industries. Bioplastics are materials that are being researched as a possible replacement for petroleum-based traditional plastics to make them more environmentally friendly. They are made from renewable resources and may be naturally recycled through biological processes, conserving natural resources and reducing CO2 emissions. The 30 chapters in the Handbook of Bioplastics and Biocomposites Engineering Applications discuss a wide range of technologies and classifications concerned with bioplastics and biocomposites with their applications in various paradigms including the engineering segment. Chapters cover the biobased materials; recycling of bioplastics; biocomposites modeling; various biomedical and engineering-based applications including optical devices, smart materials, cosmetics, drug delivery, clinical, electrochemical, industrial, flame retardant, sports, packaging, disposables, and biomass. The different approaches to sustainability are also treated. Audience The Handbook will be of central interest to engineers, scientists, and researchers who are working in the fields of bioplastics, biocomposites, biomaterials for biomedical engineering, biochemistry, and materials science. The book will also be of great importance to engineers in many industries including automotive, biomedical, construction, and food packaging.

Targeted Drug Delivery

Author : Yogeshwar Bachhav
Publisher : John Wiley & Sons
ISBN 13 : 3527827870
Total Pages : 468 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Targeted Drug Delivery by : Yogeshwar Bachhav

Download or read book Targeted Drug Delivery written by Yogeshwar Bachhav and published by John Wiley & Sons. This book was released on 2022-10-24 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: Targeted Drug Delivery Novel approaches in targeted drug delivery for both small molecule and biopharmaceutical drugs Targeted Drug Delivery explores a new frontier in drug research that has become a focus for developing novel medications. The work discusses a wide range of approaches for targeting small molecules as well as peptide and macromolecular drugs, from prodrugs to drug conjugates to drug carriers and devices, helping readers to stay up to date on the latest developments in the field. The following key topics are addressed: Antibody conjugates, prodrugs, and suicide gene therapeutics Protac technology for selectively degrading target proteins Delivery of nucleic acid drugs Novel drug carriers, such as liposomes, vesicles, and nanoparticles Unmet medical needs for which there is a large market potential, such as viral infections and cancer For chemists, pharmacologists, and professionals in the wider pharmaceutical industry, Targeted Drug Delivery is a comprehensive guide on how to solve the greatest challenge in treating many diseases: delivering a pharmaceutically active substance to the target tissue in the body.

Ionotropic Cross-Linking of Biopolymers

Author : Amit Kumar Nayak
Publisher : Elsevier
ISBN 13 : 0323996701
Total Pages : 742 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Ionotropic Cross-Linking of Biopolymers by : Amit Kumar Nayak

Download or read book Ionotropic Cross-Linking of Biopolymers written by Amit Kumar Nayak and published by Elsevier. This book was released on 2024-04-15 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ionotropic Cross-Linking of Biopolymers: Applications in Drug Delivery provides in-depth insights and presents the latest advances in ionotropic cross-linked biopolymeric systems for drug delivery and related applications. Sections introduce the fundamentals of ionotropic cross-linking of biopolymers, including mechanisms, chemistry, cross-linking methods and gelation. Additional content delves into ionotropically cross-linked biopolymers based on a range of sources, including alginate, pectinate, carboxymethyl cellulose, gellan gum, chitosan, carboxymethylated gums, plant polysaccharide blends, and synthetic polymer blends. This is followed by a section focusing on ionotropically cross-linked biopolymeric systems, such as polymeric nanoparticles, microparticles, beads, and reinforced matrices. The last part of the book explores specific advanced drug delivery applications, before considering future opportunities and challenges in the field. This is a valuable resource for researchers and advanced students across polymer science, biomaterials, biomedicine, pharmaceutics, biotechnology, and chemistry, as well as scientists and R&D personnel working in pharmacy, drug delivery, and materials for biomedicine. Explains chemistry, mechanisms, preparation methods and applications of biopolymeric systems Covers a range of biopolymer sources, including alginate, pectinate, gellan gum, chitosan, and others Guides the reader to cutting-edge applications in drug delivery, drug release, cell delivery and tissue engineering

Concepts and Models for Drug Permeability Studies

Author : Bruno Sarmento
Publisher : Elsevier
ISBN 13 : 0443155119
Total Pages : 708 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Concepts and Models for Drug Permeability Studies by : Bruno Sarmento

Download or read book Concepts and Models for Drug Permeability Studies written by Bruno Sarmento and published by Elsevier. This book was released on 2024-02-23 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concepts and Models for Drug Permeability Studies: Cell and Tissue Based in Vitro Culture Models, Second Edition, summarizes the most important developments in in vitro models for predicting the permeability of drugs. This book is structured around three different approaches, summarizing the most recent achievements regarding models comprising (i) immortalized cells with an intrinsic ability to grow as monolayers when seeded in permeable supports, (ii) primary cells isolated from living organisms and directly cultured as barrier monolayers, and (iii) tissue-based models constructed with cell lines and extracellular matrix that resembles the tridimensional structure of mucosae and other biological membranes, or animal/patient-derived tissues. Each model is covered in detail, including the protocol of generation and application for specific drugs/drug delivery systems. The equivalence between in vitro cell and tissue models and in vivo conditions is discussed, highlighting how each model may provisionally resemble different drug absorption route. Chapters included in the first edition were updated with relevant data published in recent years, while four new chapters were included to reflect new emerging directions and trends in drug permeability models. Concepts and Models for Drug Permeability Studies: Cell and Tissue Based in Vitro Culture Models, Second Edition, is a critical reference for drug discovery and drug formulation scientists interested in delivery systems intended for the administration of drugs through mucosal routes and other important tissue barriers (e.g. the BBB). Researchers studying mucosal biology can use this book to familiarize themselves and exploit the synergic effect of mucosal delivery systems and biomolecules. Summarizes the current advances in the use of permeability models in drug transport Covers the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, renal, skin, and blood–brain barrier in vitro models. Includes case studies to facilitate understanding of various concepts in computer-aided applications Updates in the second edition include organ-on-chip devices, 3D advanced models (multiple layered tissues, organoids, etc.), and multicompartmentalized tissue models

Epithelial Cell Culture

Author : Mario Baratta
Publisher : Springer Nature
ISBN 13 : 107163609X
Total Pages : 191 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Epithelial Cell Culture by : Mario Baratta

Download or read book Epithelial Cell Culture written by Mario Baratta and published by Springer Nature. This book was released on 2024-01-23 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Back Cover Copy This second edition volume expands on the previous edition with in-depth discussions on the rapid advancements in epithelial cell biology, and the cutting-edge research and techniques used by researchers in the field. The chapters in this book cover topics such as detailed methodologies applicable to epithelial cells derived from primates, pigs, bovines, and laboratory animals; the manipulation and differentiation of epithelial cells; and epithelial cell models in the gastroenteric system in human medicine and nutrition. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Epithelial Cell Culture: Methods and Protocols, Second Edition is a valuable resource for researchers in the scientific community, educators, and students who are interested in unraveling the complexities of epithelial cell biology, cultivating curiosity, and inspiring the next generation of groundbreaking research.