Biophysics And Biochemistry Of Protein Aggregation: Experimental And Theoretical Studies On Folding, Misfolding, And Self-assembly Of Amyloidogenic Peptides

Download Biophysics And Biochemistry Of Protein Aggregation: Experimental And Theoretical Studies On Folding, Misfolding, And Self-assembly Of Amyloidogenic Peptides PDF Online Free

Author :
Publisher : World Scientific
ISBN 13 : 9813202394
Total Pages : 327 pages
Book Rating : 4.8/5 (132 download)

DOWNLOAD NOW!


Book Synopsis Biophysics And Biochemistry Of Protein Aggregation: Experimental And Theoretical Studies On Folding, Misfolding, And Self-assembly Of Amyloidogenic Peptides by : Jian-min Yuan

Download or read book Biophysics And Biochemistry Of Protein Aggregation: Experimental And Theoretical Studies On Folding, Misfolding, And Self-assembly Of Amyloidogenic Peptides written by Jian-min Yuan and published by World Scientific. This book was released on 2017-06-02 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews current research on the important processes involved in neurodegenerative diseases (e.g. Alzheimer's disease) and the peptides and proteins involved in the amyloidogenic processes. It covers the design and developments of anti-amyloid inhibitors, and gives readers a fundamental understanding of the underlying oligomerization and aggregation processes of these diseases from both computational and experimental points of view.

Recent Developments In Theoretical Studies Of Proteins

Download Recent Developments In Theoretical Studies Of Proteins PDF Online Free

Author :
Publisher : World Scientific
ISBN 13 : 9814500720
Total Pages : 411 pages
Book Rating : 4.8/5 (145 download)

DOWNLOAD NOW!


Book Synopsis Recent Developments In Theoretical Studies Of Proteins by : Ron Elber

Download or read book Recent Developments In Theoretical Studies Of Proteins written by Ron Elber and published by World Scientific. This book was released on 1996-10-16 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experts provide a unique and broad perspective of the theoretical tools available today to analyze protein structure and function. Topics at the frontier of computational biophysics, such as dynamics and thermodynamics of proteins, reaction path studies, optimization techniques, analytical theories of protein folding, sequence alignment algorithms and electrostatics of proteins are discussed in a pedagogical and complete way. Those entering the field will find the book to be a useful introduction. It will also serve as a complementary text to existing ones that focus on just one of the above subjects.

Proteins

Download Proteins PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 9780471529774
Total Pages : 282 pages
Book Rating : 4.5/5 (297 download)

DOWNLOAD NOW!


Book Synopsis Proteins by : Charles L. Brooks

Download or read book Proteins written by Charles L. Brooks and published by John Wiley & Sons. This book was released on 1991-01-16 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presenting a wide-ranging view of current developments in protein research, the papers in this collection, each written by highly regarded experts in the field, examine various aspects of protein structure, functions, dynamics, and experimentation. Topics include dynamical simulation methods, the biological role of atom fluctuations, protein folding, influences on protein dynamics, and a variety of analytical techniques, such as X-ray diffraction, vibrational spectroscopy, photodissociation and rebinding kinetics. This is part of a series devoted to providing general information on a wide variety of topics in chemical physics in order to stimulate new research and to serve as a text for beginners in a particular area of chemical physics.

Biomedical Index to PHS-supported Research

Download Biomedical Index to PHS-supported Research PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 1060 pages
Book Rating : 4.:/5 (319 download)

DOWNLOAD NOW!


Book Synopsis Biomedical Index to PHS-supported Research by :

Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1990 with total page 1060 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Protein Folding Kinetics

Download Protein Folding Kinetics PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3662039664
Total Pages : 197 pages
Book Rating : 4.6/5 (62 download)

DOWNLOAD NOW!


Book Synopsis Protein Folding Kinetics by : Bengt Nölting

Download or read book Protein Folding Kinetics written by Bengt Nölting and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: First methods book which includes many detailed descriptions Absolutely needed and thus timely for the scientific community Comprises 15% more content and includes the mentioned special features

Protein Folding, Evolution and Design

Download Protein Folding, Evolution and Design PDF Online Free

Author :
Publisher : IOS Press
ISBN 13 : 9781586031695
Total Pages : 364 pages
Book Rating : 4.0/5 (316 download)

DOWNLOAD NOW!


Book Synopsis Protein Folding, Evolution and Design by : Eugene I. Shakhnovich

Download or read book Protein Folding, Evolution and Design written by Eugene I. Shakhnovich and published by IOS Press. This book was released on 2001 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents the results of broad, interdisciplinary effort to study proteins in physical and evolutionary perpective. Among authors are physicists, computational, chemists, crystallographers and evolutionary biologists. Experimental and theoretical developments from molecules to cells are presented, providing a broad picture of modern biophysical chemistry.

Research Awards Index

Download Research Awards Index PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 776 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Research Awards Index by :

Download or read book Research Awards Index written by and published by . This book was released on 1989 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Automata, Languages and Programming

Download Automata, Languages and Programming PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3540485236
Total Pages : 726 pages
Book Rating : 4.5/5 (44 download)

DOWNLOAD NOW!


Book Synopsis Automata, Languages and Programming by : Jiri Wiedermann

Download or read book Automata, Languages and Programming written by Jiri Wiedermann and published by Springer. This book was released on 2003-07-31 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 26th International Colloquium on Automata, Languages and Programming, ICALP'99, held in Prague, Czech Republic, in July 1999. The 56 revised full papers presented were carefully reviewed and selected from a total of 126 submissions; also included are 11 inivited contributions. Among the topics addressed are approximation algorithms, algebra and circuits, concurrency, semantics and rewriting, process algebras, graphs, distributed computing, logic of programs, sorting and searching, automata, nonstandard computing, regular languages, combinatorial optimization, automata and logics, string algorithms, and applied logics.

Current Topics in Computational Molecular Biology

Download Current Topics in Computational Molecular Biology PDF Online Free

Author :
Publisher : MIT Press
ISBN 13 : 9780262100922
Total Pages : 570 pages
Book Rating : 4.1/5 (9 download)

DOWNLOAD NOW!


Book Synopsis Current Topics in Computational Molecular Biology by : Tao Jiang

Download or read book Current Topics in Computational Molecular Biology written by Tao Jiang and published by MIT Press. This book was released on 2002 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: A survey of current topics in computational molecular biology. Computational molecular biology, or bioinformatics, draws on the disciplines of biology, mathematics, statistics, physics, chemistry, computer science, and engineering. It provides the computational support for functional genomics, which links the behavior of cells, organisms, and populations to the information encoded in the genomes, as well as for structural genomics. At the heart of all large-scale and high-throughput biotechnologies, it has a growing impact on health and medicine. This survey of computational molecular biology covers traditional topics such as protein structure modeling and sequence alignment, and more recent ones such as expression data analysis and comparative genomics. It combines algorithmic, statistical, database, and AI-based methods for studying biological problems. The book also contains an introductory chapter, as well as one on general statistical modeling and computational techniques in molecular biology. Each chapter presents a self-contained review of a specific subject. Not for sale in China, including Hong Kong.

The Physics of Complex Systems

Download The Physics of Complex Systems PDF Online Free

Author :
Publisher : IOS Press
ISBN 13 : 9781586034450
Total Pages : 648 pages
Book Rating : 4.0/5 (344 download)

DOWNLOAD NOW!


Book Synopsis The Physics of Complex Systems by : Franco Mallamace

Download or read book The Physics of Complex Systems written by Franco Mallamace and published by IOS Press. This book was released on 2004 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is widely known that complex systems and complex materials comprise a major interdisciplinary scientific field that draws on mathematics, physics, chemistry, biology, and medicine as well as such social sciences as economics. The role of statistical physics in this new field has been expanding. Statistical physics has shown how phenomena and processes in different research areas that have long been assumed to be unrelated can have a common description. Through the application of statistical physics, methods developed for studying order phenomena in simple systems and processes have been generalized to more complex systems. This volume focuses on recent advances and perspectives in the physics of complex systems and provides both an overview of the field and a more detailed examination of the new ideas and unsolved problems that are currently attracting the attention of researchers. This book should be a useful reference work for anyone interested in this area, whether beginning graduate student or advanced research professional. It provides up-to-date reviews on cutting-edge topics compiled by leading authorities and is designed to both broaden the reader's competence within their own field and encourage the exploration of new problems in related fields.

Multiscale Approaches to Protein Modeling

Download Multiscale Approaches to Protein Modeling PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 144196889X
Total Pages : 360 pages
Book Rating : 4.4/5 (419 download)

DOWNLOAD NOW!


Book Synopsis Multiscale Approaches to Protein Modeling by : Andrzej Kolinski

Download or read book Multiscale Approaches to Protein Modeling written by Andrzej Kolinski and published by Springer Science & Business Media. This book was released on 2010-10-13 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book gives a comprehensive review of the most advanced multiscale methods for protein structure prediction, computational studies of protein dynamics, folding mechanisms and macromolecular interactions. It approaches span a wide range of the levels of coarse-grained representations, various sampling techniques and variety of applications to biomedical and biophysical problems. This book is intended to be used as a reference book for those who are just beginning their adventure with biomacromolecular modeling but also as a valuable source of detailed information for those who are already experts in the field of biomacromolecular modeling and in related areas of computational biology or biophysics.

Structural Biology in Drug Discovery

Download Structural Biology in Drug Discovery PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118900502
Total Pages : 1437 pages
Book Rating : 4.1/5 (189 download)

DOWNLOAD NOW!


Book Synopsis Structural Biology in Drug Discovery by : Jean-Paul Renaud

Download or read book Structural Biology in Drug Discovery written by Jean-Paul Renaud and published by John Wiley & Sons. This book was released on 2020-01-09 with total page 1437 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biology in Drug Discovery: Methods, Techniques, and Practices describes principles, methods, applications, and emerging paradigms of structural biology as a tool for more efficient drug development. Coverage includes successful examples, academic and industry insights, novel concepts, and advances in a rapidly evolving field. The combined chapters, by authors writing from the frontlines of structural biology and drug discovery, give readers a valuable reference and resource that: Presents the benefits, limitations, and potentiality of major techniques in the field such as X-ray crystallography, NMR, neutron crystallography, cryo-EM, mass spectrometry and other biophysical techniques, and computational structural biology Includes detailed chapters on druggability, allostery, complementary use of thermodynamic and kinetic information, and powerful approaches such as structural chemogenomics and fragment-based drug design Emphasizes the need for the in-depth biophysical characterization of protein targets as well as of therapeutic proteins, and for a thorough quality assessment of experimental structures Illustrates advances in the field of established therapeutic targets like kinases, serine proteinases, GPCRs, and epigenetic proteins, and of more challenging ones like protein-protein interactions and intrinsically disordered proteins

Thermodynamics and Kinetics of Drug Binding

Download Thermodynamics and Kinetics of Drug Binding PDF Online Free

Author :
Publisher : John Wiley & Sons
ISBN 13 : 352733582X
Total Pages : 360 pages
Book Rating : 4.5/5 (273 download)

DOWNLOAD NOW!


Book Synopsis Thermodynamics and Kinetics of Drug Binding by : György Keserü

Download or read book Thermodynamics and Kinetics of Drug Binding written by György Keserü and published by John Wiley & Sons. This book was released on 2015-08-17 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors.

The SAGE Encyclopedia of Theory in Science, Technology, Engineering, and Mathematics

Download The SAGE Encyclopedia of Theory in Science, Technology, Engineering, and Mathematics PDF Online Free

Author :
Publisher : SAGE Publications
ISBN 13 : 1483347710
Total Pages : 1057 pages
Book Rating : 4.4/5 (833 download)

DOWNLOAD NOW!


Book Synopsis The SAGE Encyclopedia of Theory in Science, Technology, Engineering, and Mathematics by : James Mattingly

Download or read book The SAGE Encyclopedia of Theory in Science, Technology, Engineering, and Mathematics written by James Mattingly and published by SAGE Publications. This book was released on 2022-09-21 with total page 1057 pages. Available in PDF, EPUB and Kindle. Book excerpt: The SAGE Encyclopedia of Theory is a landmark work that examines theory in general and the broad split between the "hard" and "soft" sciences, a split that is being re-examined as approaches to scientific questions become increasingly multidisciplinary.

Frontiers in Protein and Peptide Sciences

Download Frontiers in Protein and Peptide Sciences PDF Online Free

Author :
Publisher : Bentham Science Publishers
ISBN 13 : 160805862X
Total Pages : 311 pages
Book Rating : 4.6/5 (8 download)

DOWNLOAD NOW!


Book Synopsis Frontiers in Protein and Peptide Sciences by : Ben Dunn

Download or read book Frontiers in Protein and Peptide Sciences written by Ben Dunn and published by Bentham Science Publishers. This book was released on 2014-07-28 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Protein and Peptide Sciences is a book series focused on leading-edge research on the structure, physical properties, and functions of proteins and peptides. Authors of contributions in this series have updated their work with new experimental data and references following their initial research. Each volume highlights a number of important topics in current research in the field of protein and peptide chemistry and molecular biology, including membrane proteins and their interactions with ligands, computational methods, and proteins in disease and biotechnology. The series is essential reading for protein chemists and researchers seeking the latest information about protein and peptide research.

Nuclease Methods and Protocols

Download Nuclease Methods and Protocols PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1592592333
Total Pages : 521 pages
Book Rating : 4.5/5 (925 download)

DOWNLOAD NOW!


Book Synopsis Nuclease Methods and Protocols by : Catherine H. Schein

Download or read book Nuclease Methods and Protocols written by Catherine H. Schein and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nucleases, enzymes that restructure or degrade nucleic acid polymers, are vital to the control of every area of metabolism. They range from “housekeeping” enzymes with broad substrate ranges to extremely specific tools (1). Many types of nucleases are used in lab protocols, and their commercial and clinical uses are expanding. The purpose of Nuclease Methods and Protocols is to introduce the reader to some we- characterized protein nucleases, and the methods used to determine their activity, structure, interaction with other molecules, and physiological role. Each chapter begins with a mini-review on a specific nuclease or a nuclease-related theme. Although many chapters cover several topics, they were arbitrarily divided into five parts: Part I, “Characterizing Nuclease Activity,” includes protocols and assays to determine general (processive, distributive) or specific mechanisms. Methods to assay nuclease products, identify cloned nucleases, and determine their physiological role are also included here. Part II, “Inhibitors and Activators of Nucleases,” summarizes assays for measuring the effects of other proteins and small molecules. Many of these inhibitors have clinical relevance. Part III, “Relating Nuclease Structure and Function,” provides an overview of methods to determine or model the 3-D structure of nucleases and their complexes with substrates and inhibitors. A 3-D structure can greatly aid the rational design of nucleases and inhibitors for specific purposes. Part IV, “Nucleases in the Clinic,” summarizes assays and protocols suitable for use with t- sues and for nuclease based therapeutics.

Research Grants Index

Download Research Grants Index PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 1132 pages
Book Rating : 4.3/5 ( download)

DOWNLOAD NOW!


Book Synopsis Research Grants Index by : National Institutes of Health (U.S.). Division of Research Grants

Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1967 with total page 1132 pages. Available in PDF, EPUB and Kindle. Book excerpt: