The Vertebrate Neuromuscular Junction

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Publisher :
ISBN 13 :
Total Pages : 464 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Vertebrate Neuromuscular Junction by : Miriam M. Salpeter

Download or read book The Vertebrate Neuromuscular Junction written by Miriam M. Salpeter and published by . This book was released on 1987 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Functional Ultrastructure

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Publisher : Springer Science & Business Media
ISBN 13 : 3211993908
Total Pages : 366 pages
Book Rating : 4.2/5 (119 download)

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Book Synopsis Functional Ultrastructure by : Margit Pavelka

Download or read book Functional Ultrastructure written by Margit Pavelka and published by Springer Science & Business Media. This book was released on 2010-07-16 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: The period between 1950 and 1980 were the golden unique insights into how pathological processes affect years of transmission electron microscopy and produced cell organization. a plethora of new information on the structure of cells This information is vital to current work in which that was coupled to and followed by biochemical and the emphasis is on integrating approaches from functional studies. TEM was king and each micrograph proteomics, molecular biology, genetics, genomics, of a new object produced new information that led to molecular imaging and physiology and pathology to novel insights on cell and tissue organization and their understand cell functions and derangements in disease. functions. The quality of data represented by the images In this current era, there is a growing tendency to of cell and tissues had been perfected to a very high level substitut e modern light microscopic techniques for by the great microscopists of that era including Palade, electron microscopy, because it is less technically Porter, Fawcett, Sjostrand, Rhodin and many others. At demanding and is more readily available to researchers- present, the images that we see in leading journals for This atlas reminds us that the information obtained by the most part do not reach the same technical level and electron microscopy is invaluable and has no substitute.

Neuroscientific Foundations of Anesthesiology

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Publisher : Oxford University Press
ISBN 13 : 0190453303
Total Pages : 296 pages
Book Rating : 4.1/5 (94 download)

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Book Synopsis Neuroscientific Foundations of Anesthesiology by : George A. Mashour

Download or read book Neuroscientific Foundations of Anesthesiology written by George A. Mashour and published by Oxford University Press. This book was released on 2011-10-05 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although the perioperative care of patients by anesthesiologists draws on diverse clinical skills, the principles of anesthesiology and pain management are rooted in the neurosciences. The Neuroscientific Foundations of Anesthesiology thoroughly examines the anesthetic modulation of the central, peripheral, and autonomic nervous systems and will help redefine anesthesiology as a fundamentally neuroscientific field. The book is organized by sections, with each focusing on a different part of the nervous system. State-of-the-art chapters written by thought-leaders in anesthesiology and neuroscience provide a novel and invaluable resource.

The Sticky Synapse

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Publisher : Springer Science & Business Media
ISBN 13 : 0387927085
Total Pages : 451 pages
Book Rating : 4.3/5 (879 download)

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Book Synopsis The Sticky Synapse by : Michael Hortsch

Download or read book The Sticky Synapse written by Michael Hortsch and published by Springer Science & Business Media. This book was released on 2009-06-07 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The molecular mechanisms, which are responsible for the functional differences between the various types of neuronal synapses, have become one of the central themes of modern neurobiology. It is becoming increasingly clear that a misregulation of synaptogenesis and synaptic remodeling and dysfunctional neuronal synapses are at the heart of several human diseases, both neurological disorders and psychiatric conditions. As synapses present specialized cellular junctions between neurons and their target cells, it may not come as a surprise that neural cell adhesion molecules (CAMs) are of special importance for the genesis and the maintenance of synaptic connections. Genes encoding adhesive molecules make up a significant portion of the human genome, and neural CAMs even have been postulated to be a major factor in the evolution of the human brain. These are just some of the many reasons why we thought a book on neural CAMs and their role in establishing and maintaining neuronal synapses would be highly appropriate for summarizing our current state of knowledge. Without question, over the near future, additional adhesive proteins will join the ranks of synaptic CAMs and our knowledge, and how these molecules enable neurons and their targets to communicate effectively will grow.

Myasthenia Gravis and Related Disorders

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Publisher : Springer Science & Business Media
ISBN 13 : 1592593410
Total Pages : 397 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Myasthenia Gravis and Related Disorders by : Henry J. Kaminski

Download or read book Myasthenia Gravis and Related Disorders written by Henry J. Kaminski and published by Springer Science & Business Media. This book was released on 2002-10-03 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: An international panel of expert clinicians and leading scientists comprehensively review the clinical and basic science of this disease and its relatives, including acquired neuromytonia and Lambert-Eaton syndrome. For the clinician, the book describes the wide range of signs and symptoms that make these diseases difficult to diagnose, review in depth the available diagnostic methods and their limitations, offer practical treatment recommendations based on years of experience, and discuss several promising treatments now emerging. For the basic scientist, the text illuminates neuromuscular structure and function, describes in detail the acetylcholine receptor (the central target of pathology in myasthenia gravis), and illuminates the autoimmune pathogenesis.

Anesthetic Pharmacology

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Publisher : Cambridge University Press
ISBN 13 : 1139497022
Total Pages : 2902 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Anesthetic Pharmacology by : Alex S. Evers

Download or read book Anesthetic Pharmacology written by Alex S. Evers and published by Cambridge University Press. This book was released on 2011-03-10 with total page 2902 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Disorders of Voluntary Muscle

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Publisher : Cambridge University Press
ISBN 13 : 9780521650625
Total Pages : 800 pages
Book Rating : 4.6/5 (56 download)

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Book Synopsis Disorders of Voluntary Muscle by : George Karpati

Download or read book Disorders of Voluntary Muscle written by George Karpati and published by Cambridge University Press. This book was released on 2001-07-12 with total page 800 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rewritten and redesigned, this remains the one essential text on the diseases of skeletal muscle.

Neuromuscular Function and Disorders

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Publisher : Butterworth-Heinemann
ISBN 13 :
Total Pages : 382 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Neuromuscular Function and Disorders by : Alan J. McComas

Download or read book Neuromuscular Function and Disorders written by Alan J. McComas and published by Butterworth-Heinemann. This book was released on 1977 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuromuscular Function and Disorders focuses on the various processes underlying disordered neuromuscular function. Topics covered include the nature of membrane defects in myotonia and familial periodic paralysis; the disorder of neuromuscular transmission responsible for myasthenia gravis and the various pseudo-myasthenic syndromes; and the disorders of Schwann cell function which cause demyelination. This book is comprised of 28 chapters divided into two sections and begins with a discussion on the normal anatomy and physiology of peripheral nerve and muscle. Included in the first section a ...

Neuromuscular Junctions in Drosophila

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Publisher : Academic Press
ISBN 13 : 9780080857770
Total Pages : 289 pages
Book Rating : 4.8/5 (577 download)

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Book Synopsis Neuromuscular Junctions in Drosophila by :

Download or read book Neuromuscular Junctions in Drosophila written by and published by Academic Press. This book was released on 1999-04-29 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuromuscular Junctions in Drosophila gathers the main contributions that research using the fruit fly Drosophila melanogaster has made in the area of synapse development, synapse physiology, and excitability of muscles and nerve cells. The chapters in this book represent a synthesis of major advances in our understanding of neuronal development and synaptic physiology, which have been obtained using the above approach. This book is directed to the general neuroscience audience: researchers, instructors, graduate students, and advanced undergraduates who are interested in the mechanisms of synapse development and physiology. However, the book will also be a valuable resource for those that use the fruit fly as a model system in their laboratories. Key Features * Synthesizes the genetic approaches used to study synaptic development and function at the neuromuscular junction, using flies as a model system * Covers major recent advances in muscle development, pathfinding, synapse maturation and plasticity, exo- and endocytosis, and ion channel function * Written in clear language that is easily understandable to readers not already familiar with fruit fly research * Includes numerous diagrams and extensive reference lists

Vertebrate Motoneurons

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Publisher : Springer Nature
ISBN 13 : 3031071670
Total Pages : 403 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Vertebrate Motoneurons by : Michael J. O'Donovan

Download or read book Vertebrate Motoneurons written by Michael J. O'Donovan and published by Springer Nature. This book was released on 2022-09-06 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide a comprehensive and timely review of new findings in motoneuron research. Recent findings have revealed that motoneurons are more complex and have more extensive functions than previously imagined. Some of the molecular and genetic pathways that orchestrate the development of motoneurons have been discovered, as have the mechanisms responsible for the selective innervation of muscles by specific pools of motoneurons. These novel findings are revolutionizing ideas about the function of motoneurons and have important implications for motoneuron disease. Chapters from several of the foremost figures in the field are included in this book and will emphasize how basic science is the engine driving the discovery of novel treatments for degenerative motoneuron diseases. Cutting edge developments in the use of pluripotent stem cells to correct motoneuron disease will be also be covered. This book would be useful to students of basic motoneuron physiology, locomotor behavior and motor control. This book would also be of interest to professional neuroscientists, neurologists, and neurosurgeons.

The Peripheral Nervous System

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Publisher : Springer Science & Business Media
ISBN 13 : 1461586992
Total Pages : 536 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis The Peripheral Nervous System by : John Hubbard

Download or read book The Peripheral Nervous System written by John Hubbard and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: The peripheral nervous system is usually defined as the cranial nerves, spinal nerves, and peripheral ganglia which lie outside the brain and spinal cord. To describe the structure and function of this system in one book may have been possible last century. Today, only a judicious selection is possible. It may be fairly claimed that the title of this book is not misleading, for in keeping the text within bounds only accounts of olfaction, vision, audition, and vestibular function have been omitted, and as popularly understood these topics fall into the category of special senses. This book contains a comprehensive treatment of the structure and function of peripheral nerves (including axoplasmic flow and trophic func tions); junctional regions in the autonomic and somatic divisions of the peripheral nervous system; receptors in skin, tongue, and deeper tissues; and the integrative role of ganglia. It is thus a handbook of the peripheral nervous system as it is usually understood for teaching purposes. The convenience of having this material inside one set of covers is already proven, for my colleagues were borrowing parts of the text even while the book was in manuscript. It is my belief that lecturers will find here the information they need, while graduate students will be able to get a sound yet easily read account of results of research in their area. JOHN 1. HUBBARD vii Contents SECTION I-PERIPHERAL NERVE Chapter 1 Peripheral Nerve Structure 3 Henry deF. Webster 3 1. Introduction .

The Fly Neuromuscular Junction: Structure and Function

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Publisher : Elsevier
ISBN 13 : 0080469132
Total Pages : 424 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis The Fly Neuromuscular Junction: Structure and Function by : Vivian Budnik

Download or read book The Fly Neuromuscular Junction: Structure and Function written by Vivian Budnik and published by Elsevier. This book was released on 2006-11-02 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Drosophila larval neuromuscular junction (NMJ) has become one of the most powerful model systems to ask key neurobiological questions. This synapse is unparalleled by its accessibility, its simplicity, and the ability to manipulate genes important for synapse development and function. Its synapses have properties shared by many organisms including humans. The vast majority of genes that when mutated cause congenital disorders of the nervous system in humans, are present in the fruit fly genome, and fly models of human disorders are available. Thus, this preparation is a powerful tool to understand the normal function of these genes. This book reviews outstanding work by recognized leaders in the fields of Drosophila cellular neurogenetics including developmental neurobiology, mechanisms of synaptic function, and experience dependent changes at synapses. The book also includes step-by-step protocols to study the cellular biology of the NMJ, making it a vital resource for researchers beginning their investigations with this system, for those who are training students and postdoctoral fellows in this area, or simply as a general reference material for neuroscientists and neuroscience professors in general. * Provides a synthesis of the main topics in modern neurogenetics * Includes step-by-step protocols for the use of the Drosophila NMJ system in neurobiology lab research * Offers genetic approaches to study synapse development and function *

The Synapse: In Development, Health, and Disease

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Publisher : Elsevier Science
ISBN 13 : 9780762302222
Total Pages : 0 pages
Book Rating : 4.3/5 (22 download)

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Book Synopsis The Synapse: In Development, Health, and Disease by : B.W. Festoff

Download or read book The Synapse: In Development, Health, and Disease written by B.W. Festoff and published by Elsevier Science. This book was released on 1997-05-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume came out of discussions with Professeur Michel Fardeau my long-time colleague in Paris and now Directeur of the Institut de Myologie at the Hopital Pitie-Salpetriere there, and Professeur Emeritus Rene Couteaux, Universite de Paris VI. During my sabbatical year 1994-95, as Professeur de L'Academie des Sciences and Chaire Elf Aquitaine in Paris, Professeur Couteaux and I had a number of discussions, centering on the development of the field of synaptology from his perspective as one who had experienced many of the significant advances during his active professional career. Following these discussions, my colleagues, Daniel Hantai in Paris, and Bruce Citron in Kansas City, and I began to contact scientists in various areas of current synapse research. The result in this volume which seeks to incorporate studies in development, maintenance, and disease states. The foreword by Professeur Couteaux is a remarkable personal journey through the beginnings of this field up to the present day. Professeur Couteaux has continued to be active in his own research on the neuromuscular synapse to this day.

Muscle Development in Drosophilia

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Publisher : Springer Science & Business Media
ISBN 13 : 9780387300535
Total Pages : 224 pages
Book Rating : 4.3/5 (5 download)

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Book Synopsis Muscle Development in Drosophilia by : Helen Sink

Download or read book Muscle Development in Drosophilia written by Helen Sink and published by Springer Science & Business Media. This book was released on 2006-02-02 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: The different aspects of muscle development are considered from cellular, molecular and genetic viewpoints, and the text is supported by black/white and color illustrations. The book will appeal to those studying muscle development and muscle biology in any organism.

A Study of Miniature Endplate Current Generation at the Vertebrate Neuromuscular Jucntion Using Electrophysiology and Monte Carlo Simulation

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Publisher :
ISBN 13 :
Total Pages : 526 pages
Book Rating : 4.E/5 ( download)

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Book Synopsis A Study of Miniature Endplate Current Generation at the Vertebrate Neuromuscular Jucntion Using Electrophysiology and Monte Carlo Simulation by : Thomas M. Bartol

Download or read book A Study of Miniature Endplate Current Generation at the Vertebrate Neuromuscular Jucntion Using Electrophysiology and Monte Carlo Simulation written by Thomas M. Bartol and published by . This book was released on 1992 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Electromyography and Neuromuscular Disorders E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 1455744735
Total Pages : 663 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Electromyography and Neuromuscular Disorders E-Book by : David C. Preston

Download or read book Electromyography and Neuromuscular Disorders E-Book written by David C. Preston and published by Elsevier Health Sciences. This book was released on 2012-12-01 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnose neuromuscular disorders more quickly and accurately with Electromyography and Neuromuscular Disorders: Clinical-Electrophysiologic Correlations, 3rd Edition! State-of-the-art guidance helps you correlate electromyographic and clinical findings and use the latest EMG techniques to their fullest potential. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Successfully correlate electrodiagnostic findings with key clinical findings for more confident diagnoses. Clearly see how to apply what you’ve learned with abundant case studies throughout the book. Obtain relevant clinical guidance quickly and easily with an accessible, easy-to-read writing style that’s both comprehensive and easy to understand. Ensure correct EMG needle placement and avoid neurovascular injuries by referring to more than 65 detailed, cross-sectional anatomy drawings. Diagnose many newly defined genetic neuromuscular conditions based on their electrodiagnostic presentation. Stay up to date with must-know information on iatrogenic complications of electrodiagnostic studies. Visualize key concepts more easily with a brand-new full-color design, new artwork, and new photographs. Access Electromyography and Neuromuscular Disorders online, fully searchable, at www.expertconsult.com, along with more than 70 videos that allow you to see and hear the EMG waveforms discussed in the text, as well as a convenient "test yourself" module.

Spinal Muscular Atrophy

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Publisher : Academic Press
ISBN 13 : 0128036869
Total Pages : 506 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Spinal Muscular Atrophy by : Charlotte J Sumner

Download or read book Spinal Muscular Atrophy written by Charlotte J Sumner and published by Academic Press. This book was released on 2016-10-24 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spinal Muscular Atrophy: Disease Mechanisms and Therapy provides the latest information on a condition that is characterized by motoneuron loss and muscle atrophy, and is the leading genetic cause of infant mortality. Since the identification of the gene responsible for SMA in 1995, there have been important advances in the basic understanding of disease mechanisms, and in therapeutic development. This book provides a comprehensive accounting of recent advances in basic and clinical research that covers SMA clinical features and standards of care, multifaceted aspects of SMN protein functions and SMA disease pathology, various animal models, and biomarkers, as well as current therapeutic development. This title is ideal for graduate students/postdocs and principal investigators who are already in the SMA field and need to keep updated on recent findings and approaches, and for those who are new to, or would like to join, the field. Likewise, users will find an excellent source of reading for biotech/pharma scientists, clinical researchers, and practitioners, regulators, and patients and their advocacy organizations. Furthermore, this book is a handy reference for researchers and clinicians who may want to apply the research strategies and therapeutic approaches in SMA to other rare diseases. Provides comprehensive, up-to-date reviews by leading investigators on diverse topics of SMA, including clinical features and patient care, SMN genetics and protein functions, animal models, disease pathology and mechanisms, biomarkers, current therapeutic development, and the role of non-profit organizations in therapeutic development Written to bridge multiple disciplines and promote better communications among basic scientists, clinical researchers, and health care providers on the latest developments in SMA Includes outstanding questions and perspectives for future investigations and key references for additional detailed study